Faculty

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Andrew F. Ippoliti, MD
Professor of Clinical Medicine
Medicine
IRD 709 2020 Zonal Avenue Health Sciences Campus Los Angeles

Overview

Dr. Ippoliti has extensive experience in gastroenterology and is a well-known expert both nationally and locally. He previously was on the faculty at the David Geffen School of Medicine at UCLA where he rose to a professor in clinical medicine. Later he joined the faculty at Cedars-Sinai Medical Center and was the associate chief of gastroenterology for over a decade. He has now moved to the Keck Medicine of USC in the same capacity.

He has been involved in the training of many of the gastroenterologists practicing in the Los Angeles area and sees many second opinion consultations from them. He is known nationally as a key thought leader in inflammatory bowel disease and in gastroesophageal reflux disease. He has served on many advisory boards and has lectured at medical centers around the country and abroad.

Publications

Outcomes with Anti-Tumour Necrosis Factor-Alpha Therapy and Serology in Patients with Denovo Crohn's Disease After Ileal Pouch Anal Anastomosis. J Crohns Colitis. 2017 Jan; 11(1):77-83. View in: PubMed

Microgeographic Proteomic Networks of the Human Colonic Mucosa and Their Association With Inflammatory Bowel Disease. Cell Mol Gastroenterol Hepatol. 2016 Sep; 2(5):567-583. View in: PubMed

Outcomes with Anti-Tumour Necrosis Factor-Alpha Therapy and Serology in Patients with Denovo Crohn's Disease After Ileal Pouch Anal Anastomosis. J Crohns Colitis. 2016 Jul 27. View in: PubMed

Perianal Crohn's Disease is Associated with Distal Colonic Disease, Stricturing Disease Behavior, IBD-Associated Serologies and Genetic Variation in the JAK-STAT Pathway. Inflamm Bowel Dis. 2016 Apr; 22(4):862-9. View in: PubMed

Nonbloody Diarrhea but Not Significant Weight Loss at Diagnosis Is Associated with the Development of Denovo Crohn's Disease After Ileal Pouch-anal Anastomosis for Ulcerative Colitis. Inflamm Bowel Dis. 2016 Mar; 22(3):654-61. View in: PubMed

Colectomy with Permanent End Ileostomy Is More Cost-Effective than Ileal Pouch-Anal Anastomosis for Crohn's Colitis. Dig Dis Sci. 2016 Feb; 61(2):550-9. View in: PubMed

Ocular Manifestations in Inflammatory Bowel Disease Are Associated with Other Extra-intestinal Manifestations, Gender, and Genes Implicated in Other Immune-related Traits. J Crohns Colitis. 2016 Jan; 10(1):43-9. View in: PubMed

Combined Immunosuppression Impairs Immunogenicity to Tetanus and Pertussis Vaccination Among Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis. 2015 Aug; 21(8):1754-60. View in: PubMed

The impact of preoperative serum anti-TNFa therapy levels on early postoperative outcomes in inflammatory bowel disease surgery. Ann Surg. 2015 Mar; 261(3):487-96. View in: PubMed

Pyoderma Gangrenosum among Patients with Inflammatory Bowel Disease: A Descriptive Cohort Study. J Cutan Med Surg. 2015 Mar-Apr; 19(2):125-31. View in: PubMed

Pyoderma Gangrenosum among Patients with Inflammatory Bowel Disease: A Descriptive Cohort Study. J Cutan Med Surg. 2015 Mar; 19(2):125-31. View in: PubMed

Pyoderma Gangrenosum among Patients with Inflammatory Bowel Disease: A Descriptive Cohort Study. J Cutan Med Surg. 2014 Oct; 18(5):361. View in: PubMed

Antibiotics for Treatment of Clostridium difficile Infection in Hospitalized Patients with Inflammatory Bowel Disease. Antimicrob Agents Chemother. 2014 Sep; 58(9):5054-9. View in: PubMed

Clinical, serologic, and genetic factors associated with pyoderma gangrenosum and erythema nodosum in inflammatory bowel disease patients. Inflamm Bowel Dis. 2014 Mar; 20(3):525-33. View in: PubMed

Multidimensional prognostic risk assessment identifies association between IL12B variation and surgery in Crohn's disease. Inflamm Bowel Dis. 2013 Jul; 19(8):1662-70. View in: PubMed

Assessing health status in inflammatory bowel disease using a novel single-item numeric rating scale. Dig Dis Sci. 2013 May; 58(5):1313-21. View in: PubMed

A modular organization of the human intestinal mucosal microbiota and its association with inflammatory bowel disease. PLoS One. 2013; 8(11):e80702. View in: PubMed

Surgical outcome of ileal pouch-anal anastomosis when used intentionally for well-defined Crohn's disease. Inflamm Bowel Dis. 2013 Jan; 19(1):30-6. View in: PubMed

Colorectal cancer screening and surveillance in Crohn's colitis. J Crohns Colitis. 2012 Sep; 6(8):824-9. View in: PubMed

Does preoperative immunosuppression influence unplanned hospital readmission after surgery in patients with Crohn's disease? Dis Colon Rectum. Does preoperative immunosuppression influence unplanned hospital readmission after surgery in patients with Crohn's disease? Dis Colon Rectum. 2012 May; 55(5):563-8. View in: PubMed

Host-microbe relationships in inflammatory bowel disease detected by bacterial and metaproteomic analysis of the mucosal-luminal interface. Inflamm Bowel Dis. 2012 Mar; 18(3):409-17. View in: PubMed

Variants in ZNF365 isoform D are associated with Crohn's disease. Gut. 2011 Aug; 60(8):1060-7. View in: PubMed

A metaproteomic approach to study human-microbial ecosystems at the mucosal luminal interface. PLoS One. 2011; 6(11):e26542. View in: PubMed

Genetic predictors of medically refractory ulcerative colitis. Inflamm Bowel Dis. 2010 Nov; 16(11):1830-40. View in: PubMed

Combination of innate and adaptive immune alterations increased the likelihood of fibrostenosis in Crohn's disease. Inflamm Bowel Dis. 2010 Aug; 16(8):1279-85. View in: PubMed

New clinical method for distinguishing D-IBS from other gastrointestinal conditions causing diarrhea: the LA/IBS diagnostic strategy. Dig Dis Sci. 2010 Jan; 55(1):145-9. View in: PubMed

Immunosuppression impairs response to pneumococcal polysaccharide vaccination in patients with inflammatory bowel disease. Am J Gastroenterol. 2010 Jan; 105(1):148-54. View in: PubMed

Capsule endoscopy in patients with Crohn's disease: diagnostic yield and safety. Gastrointest Endosc. 2010 Jan; 71(1):121-7. View in: PubMed

A prospective evaluation of the long-term outcome of ileal pouch-anal anastomosis in patients with inflammatory bowel disease-unclassified and indeterminate colitis. Dis Colon Rectum. 2009 May; 52(5):872-8. View in: PubMed

Esophageal perforation from a metal screw and plate. Gastrointest Endosc. 2009 Apr; 69(4):948; discussion 948-9. View in: PubMed

High-frequency haplotypes in the X chromosome locus TLR8 are associated with both CD and UC in females. Inflamm Bowel Dis. 2009 Mar; 15(3):321-7. View in: PubMed

Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study. Nat Genet. 2009 Feb; 41(2):216-20. View in: PubMed

IL23R haplotypes provide a large population attributable risk for Crohn's disease. Inflamm Bowel Dis. 2008 Sep; 14(9):1185-91. View in: PubMed

Both preoperative perinuclear antineutrophil cytoplasmic antibody and anti-CBir1 expression in ulcerative colitis patients influence pouchitis development after ileal pouch-anal anastomosis. Clin Gastroenterol Hepatol. 2008 May; 6(5):561-8. View in: PubMed

Family history and serology predict Crohn's disease after ileal pouch-anal anastomosis for ulcerative colitis. Dis Colon Rectum. 2008 Jan; 51(1):100-8. View in: PubMed

Hepatotoxicity of 6-mercaptopurine (6-MP) and Azathioprine (AZA) in adult IBD patients. Am J Gastroenterol. 2007 Nov; 102(11):2488-94. View in: PubMed

Does infliximab influence surgical morbidity of ileal pouch-anal anastomosis in patients with ulcerative colitis? Dis Colon Rectum. Does infliximab influence surgical morbidity of ileal pouch-anal anastomosis in patients with ulcerative colitis? Dis Colon Rectum. 2007 Nov; 50(11):1747-53. View in: PubMed

Mucormycosis presenting as recurrent gastric perforation in a patient with Crohn's disease on glucocorticoid, 6-mercaptopurine, and infliximab therapy. Dig Dis Sci. 2007 Sep; 52(9):2078-81. View in: PubMed

A prospective multivariate analysis of clinical factors associated with pouchitis after ileal pouch-anal anastomosis. Clin Gastroenterol Hepatol. 2007 Aug; 5(8):952-8; quiz 887. View in: PubMed

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet. 2007 May; 39(5):596-604. View in: PubMed

Predicting a change in diagnosis from ulcerative colitis to Crohn's disease: a nested, case-control study. Clin Gastroenterol Hepatol. 2007 May; 5(5):602-8; quiz 525. View in: PubMed

Anti-flagellin (CBir1) phenotypic and genetic Crohn's disease associations. Inflamm Bowel Dis. 2007 May; 13(5):524-30. View in: PubMed

NOD2 variants and antibody response to microbial antigens in Crohn's disease patients and their unaffected relatives. Gastroenterology. 2007 Feb; 132(2):576-86. View in: PubMed

Antibodies to I2 predict clinical response to fecal diversion in Crohn's disease. Inflamm Bowel Dis. 2006 Dec; 12(12):1122-30. View in: PubMed

Patients with inflammatory bowel disease are at risk for vaccine-preventable illnesses. Am J Gastroenterol. 2006 Aug; 101(8):1834-40. View in: PubMed

Familial expression of anti-Escherichia coli outer membrane porin C in relatives of patients with Crohn's disease. Gastroenterology. 2006 Apr; 130(4):1078-85. View in: PubMed

Elevated platelet count before ileal pouch-anal anastomosis for ulcerative colitis is associated with the development of chronic pouchitis. Am Surg. 2005 Oct; 71(10):821-6. View in: PubMed

Randomized trial of argon plasma coagulation vs. multipolar electrocoagulation for ablation of Barrett's esophagus. Gastrointest Endosc. 2005 Feb; 61(2):232-40. View in: PubMed

Safety and efficacy of adalimumab (D2E7) in Crohn's disease patients with an attenuated response to infliximab. Am J Gastroenterol. 2005 Jan; 100(1):75-9. View in: PubMed

A pilot study of adalimumab in infliximab-allergic patients. Inflamm Bowel Dis. 2004 Jul; 10(4):333-8. View in: PubMed

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