Matthew Kirkpatrick, PhD

Matt Kirkpatrick, PhD is an Associate Professor of Research in the Department of Population and Public Health Sciences in the Keck School of Medicine at the University of Southern California. He is the PI of the Drug Use & Behavior Laboratory (DUB Lab), which uses behavioral pharmacology, Ecological Momentary Assessment, and survey methods to focus on how drugs – including stimulants, cannabis, alcohol, and tobacco – function in social contexts, with an emphasis on how friends and family influence which drugs an individual uses, how much they use, whether or not they develop problematic use, and—if they do—whether or not they’ll be successful at quitting.

Dr. Kirkpatrick earned his B.A. in Religious Studies at the University of North Carolina at Chapel Hill and Ph.D. in Psychology at Columbia University. Dr. Kirkpatrick completed postdoctoral training in neuropsychopharmacology at the University of Chicago.

• Oral Nicotine Gum Discussions on Twitter: Content Analysis Nicotine Tob Res. 2024 Mar 22; 26(4):503-507. . View in PubMed
• Effects of cannabis use on cigarette smoking cessation in LGBTQ+ individuals Psychol Addict Behav. 2024 Mar 14. . View in PubMed
• Assessing the public discourse on Twitter: Reactions to the JUUL e-cigarettes ban in the United States Tob Induc Dis. 2024; 22. . View in PubMed
• Characterizing Opioid Withdrawal Experiences and Consequences Among a Community Sample of People Who Use Opioids Subst Use Misuse. 2024; 59(6):886-894. . View in PubMed
• Adolescent and Parent Perceptions of Postoperative Opioid Use: A Qualitative, Thematic Analysis J Pediatr Surg. 2023 Dec 19. . View in PubMed
• Cartoon marketing exposure decreases perceived risks of e-cigarette use in adolescents Exp Clin Psychopharmacol. 2023 Dec; 31(6):1032-1038. . View in PubMed
• Nicotine deprivation amplifies attentional bias toward racial discrimination stimuli in African American adults who smoke cigarettes Exp Clin Psychopharmacol. 2023 Dec; 31(6):1023-1031. . View in PubMed
• Effect of a mindfulness training app on a cigarette quit attempt: an investigator-blinded, 58-county randomized controlled trial JNCI Cancer Spectr. 2023 Oct 31; 7(6). . View in PubMed
• The role of social variables in drug use and addiction Pharmacol Biochem Behav. 2023 Oct 05; 232:173656. . View in PubMed
• Dose-response effects of two nicotine salt formulations on electronic cigarette appeal and sensory attributes Tob Control. 2023 Jan 02. . View in PubMed
• Associations of DHEA(S) with negative and positive affect in people who smoke daily with elevated and low depression symptoms: A pilot laboratory study Addict Behav. 2023 11; 146:107801. . View in PubMed
• E-cigarette use and promotion by social media influencers during videogame play on Twitch Tob Control. 2023 07; 32(4):526-527. . View in PubMed
• Emotion regulation expectancies and smoking cessation factors: A daily diary study of California adults who smoke cigarettes during a practice quit attempt Drug Alcohol Depend. 2023 04 01; 245:109810. . View in PubMed
• Interactive associations between abstinence plans and romantic partner conflict and support with cigarette smoking Drug Alcohol Depend. 2023 02 01; 243:109756. . View in PubMed
• Implementation planning for equitable tobacco treatment services: a mixed methods assessment of contextual facilitators and barriers in a large comprehensive cancer center Transl Behav Med. 2023 08 11; 13(8):539-550. . View in PubMed
• Interactions between daily abstinence plans and approach/avoidance motivation on cigarette smoking in pre-quit smokers Exp Clin Psychopharmacol. 2022 Oct; 30(5):666-672. . View in PubMed
• Test of daily app-based mindfulness meditation preceding a planned smoking quit attempt date on abstinence: Protocol for a randomized controlled trial recruiting across the 58 counties of California Contemp Clin Trials. 2022 09; 120:106855. . View in PubMed
• Exposure to E-Cigarette Product Placement in Music Videos Is Associated With Vaping Among Young Adults Health Educ Behav. 2022 08; 49(4):639-646. . View in PubMed
• Recognition of cartoon-based e-cigarette-related marketing is associated with e-cigarette use among adolescents Addict Behav. 2022 07; 130:107312. . View in PubMed
• The impact of e-cigarette product place in music videos on susceptibility to use e-cigarettes among young adults: An experimental investigation Addict Behav. 2022 07; 130:107307. . View in PubMed
• Effects of cigarette abstinence on negative and positive affect by depression symptom levels: A lab study J Affect Disord. 2022 06 15; 307:163-170. . View in PubMed
• Ice Flavor-Related Discussions on Twitter: Content Analysis J Med Internet Res. 2022 11 30; 24(11):e41785. . View in PubMed
• Association of depression symptom level with smoking urges, cigarette withdrawal, and smoking reinstatement: A preliminary laboratory study Drug Alcohol Depend. 2022 03 01; 232:109267. . View in PubMed
• Social facilitation of alcohol subjective effects in adolescents: Associations with subsequent alcohol use Psychopharmacology (Berl). 2021 Mar; 238(3):887-897. . View in PubMed
• Impact of self-efficacy on daily intention to not smoke Addict Behav. 2021 07; 118:106877. . View in PubMed
• Developmental patterns of tobacco product and cannabis use initiation in high school Addiction. 2021 02; 116(2):382-393. . View in PubMed
• #FlavorsSaveLives: An Analysis of Twitter Posts Opposing Flavored E-cigarette Bans Nicotine Tob Res. 2021 08 04; 23(8):1431-1435. . View in PubMed
• Guidelines for Opioid Prescribing in Children and Adolescents After Surgery: An Expert Panel Opinion JAMA Surg. 2021 01 01; 156(1):76-90. . View in PubMed
• Concerns About Pediatric Opioid Prescribing Guidelines-Reply JAMA Surg. 2021 09 01; 156(9):892-893. . View in PubMed
• Factors associated with methamphetamine withdrawal symptoms among people who inject drugs Drug Alcohol Depend. 2021 06 01; 223:108702. . View in PubMed
• Topics of Nicotine-Related Discussions on Twitter: Infoveillance Study J Med Internet Res. 2021 06 07; 23(6):e25579. . View in PubMed
• Electronic Cigarette Product Placement and Imagery in Popular Music Videos Nicotine Tob Res. 2021 08 04; 23(8):1367-1372. . View in PubMed
• Subjective effects from the first cigarette of the day vary with precigarette affect in premenopausal female daily smokers Exp Clin Psychopharmacol. 2020 Jun; 28(3):299-305. . View in PubMed
• Effectiveness of transdermal nicotine patch in premenopausal female smokers is moderated by within-subject severity of negative affect and physical symptoms Psychopharmacology (Berl). 2020 Jun; 237(6):1737-1744. . View in PubMed
• Indirect Associations of Anxiety Sensitivity with Tobacco, Alcohol, and Other Drug Use Problems Through Emotional Disorder Symptoms in Adolescents Behav Med. 2020 Apr-Jun; 46(2):161-169. . View in PubMed
• Sex differences in the appeal of flavored e-cigarettes among young adult e-cigarette users Psychol Addict Behav. 2020 Mar; 34(2):303-307. . View in PubMed
• Sensory attributes of e-cigarette flavours and nicotine as mediators of interproduct differences in appeal among young adults Tob Control. 2020 11; 29(6):679-686. . View in PubMed
• E-cigarette device power moderates the effects of non-tobacco flavors and nicotine on product appeal in young adults Addict Behav. 2020 08; 107:106403. . View in PubMed
• Characterising KandyPens-related posts to Instagram: implications for nicotine and cannabis use Tob Control. 2020 07; 29(4):472-474. . View in PubMed
• Detection of acute 3,4-methylenedioxymethamphetamine (MDMA) effects across protocols using automated natural language processing Neuropsychopharmacology. 2020 04; 45(5):823-832. . View in PubMed
• Conceptualizing Health Behaviors as Acute Mood-Altering Agents: Implications for Cancer Control Cancer Prev Res (Phila). 2020 04; 13(4):343-350. . View in PubMed
• Content Analysis of Instagram Posts From 2019 With Cartoon-Based Marketing of e-Cigarette-Associated Products JAMA Pediatr. 2020 11 01; 174(11):1110-1112. . View in PubMed
• Subjective effects of combustible, vaporized, and edible cannabis: Results from a survey of adolescent cannabis users Drug Alcohol Depend. 2020 01 01; 206:107716. . View in PubMed
• Digital media use and subsequent cannabis and tobacco product use initiation among adolescents Drug Alcohol Depend. 2020 07 01; 212:108017. . View in PubMed
• Initial application of a human laboratory model for estimating the motivational substitutability of e-cigarettes for combustible cigarettes Exp Clin Psychopharmacol. 2019 Apr; 27(2):125-135. . View in PubMed
• Flavored E-cigarette Use and Progression of Vaping in Adolescents Pediatrics. 2019 11; 144(5). . View in PubMed
• Return of cartoon to market e-cigarette-related products Tob Control. 2019 09; 28(5):555-557. . View in PubMed
• Strategies to find audience segments on Twitter for e-cigarette education campaigns Addict Behav. 2019 04; 91:222-226. . View in PubMed
• Validation of a behavioral economic purchase task for assessing drug abuse liability Addict Biol. 2019 03; 24(2):303-314. . View in PubMed
• Cartoon-based e-cigarette marketing: Associations with susceptibility to use and perceived expectations of use Drug Alcohol Depend. 2019 08 01; 201:109-114. . View in PubMed
• Effects of non-tobacco flavors and nicotine on e-cigarette product appeal among young adult never, former, and current smokers Drug Alcohol Depend. 2019 10 01; 203:99-106. . View in PubMed
• Pain as a predictor and consequence of tobacco abstinence effects amongst African American smokers J Abnorm Psychol. 2018 Oct; 127(7):683-694. . View in PubMed
• Rewarding effects of physical activity predict sensitivity to the acute subjective effects of d-amphetamine in healthy volunteers J Psychopharmacol. 2018 03; 32(3):302-308. . View in PubMed
• Ovarian Hormones and Transdermal Nicotine Administration Independently and Synergistically Suppress Tobacco Withdrawal Symptoms and Smoking Reinstatement in the Human Laboratory Neuropsychopharmacology. 2018 03; 43(4):828-837. . View in PubMed
• Monitoring Tobacco Brand Websites to Understand Marketing Strategies Aimed at Tobacco Product Users and Potential Users Nicotine Tob Res. 2018 09 25; 20(11):1393-1400. . View in PubMed
• Anhedonia and Abstinence as Predictors of the Subjective Pleasantness of Positive, Negative, and Smoking-Related Pictures Nicotine Tob Res. 2017 Jun 01; 19(6):743-749. . View in PubMed
• Electronic cigarette retailers use Pokémon Go to market products Tob Control. 2017 12; 26(e2):e145-e147. . View in PubMed
• Impulsivity and history of behavioral addictions are associated with drug use in adolescents Addict Behav. 2017 11; 74:41-47. . View in PubMed
• Pharmacogenetics of stimulant abuse liability: association of CDH13 variant with amphetamine response in a racially-heterogeneous sample of healthy young adults Psychopharmacology (Berl). 2017 Jan; 234(2):307-315. . View in PubMed
• Effects of sweet flavorings and nicotine on the appeal and sensory properties of e-cigarettes among young adult vapers: Application of a novel methodology Drug Alcohol Depend. 2016 Nov 01; 168:176-180. . View in PubMed
• Transdiagnostic processes linking anxiety symptoms and substance use problems among adolescents J Addict Dis. 2016 Oct-Dec; 35(4):266-277. . View in PubMed
• Premenstrual symptoms and smoking-related expectancies Addict Behav. 2016 Jun; 57:38-41. . View in PubMed
• Asians compared to Whites show increased response to d-amphetamine on select subjective and cardiovascular measures Pharmacol Biochem Behav. 2016 May; 144:73-7. . View in PubMed
• Social contexts of momentary craving to smoke among Korean American emerging adults Addict Behav. 2016 May; 56:23-9. . View in PubMed
• Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium Behav Genet. 2016 Mar; 46(2):170-82. . View in PubMed
• Psychiatric comorbidity in adolescent electronic and conventional cigarette use J Psychiatr Res. 2016 Feb; 73:71-8. . View in PubMed
• Urinary and plasma oxytocin changes in response to MDMA or intranasal oxytocin administration Psychoneuroendocrinology. 2016 12; 74:92-100. . View in PubMed
• Oxytocin receptor gene variation predicts subjective responses to MDMA Soc Neurosci. 2016 12; 11(6):592-9. . View in PubMed
• Emotional traits predict individual differences in amphetamine-induced positive mood in healthy volunteers Psychopharmacology (Berl). 2016 Jan; 233(1):89-97. . View in PubMed
• Social Self-Control Is a Statistically Nonredundant Correlate of Adolescent Substance Use Subst Use Misuse. 2016 05 11; 51(6):788-94. . View in PubMed
• Diminished Alternative Reinforcement as a Mechanism Underlying Socioeconomic Disparities in Adolescent Substance Use Prev Med. 2015 Nov; 80:75-81. . View in PubMed
• Initial Validation of the Pleasure and Health Behavior Inventory – A Measure of Motivation to Engage in Health-damaging Behavior to Overcome Deficient Pleasure Am J Health Behav. 2015 Sep; 39(5):652-64. . View in PubMed
• Pharmacological, sensorimotor, and expectancy effects on tobacco withdrawal: a preliminary study Hum Psychopharmacol. 2015 Sep; 30(5):364-71. . View in PubMed
• Association of Electronic Cigarette Use With Initiation of Combustible Tobacco Product Smoking in Early Adolescence JAMA. 2015 Aug 18; 314(7):700-7. . View in PubMed
• Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder JAMA Psychiatry. 2015 Jul; 72(7):642-50. . View in PubMed
• Effects of acute doses of prosocial drugs methamphetamine and alcohol on plasma oxytocin levels J Clin Psychopharmacol. 2015 Jun; 35(3):308-12. . View in PubMed
• Prosocial effects of MDMA: A measure of generosity J Psychopharmacol. 2015 Jun; 29(6):661-8. . View in PubMed
• Intimate insight: MDMA changes how people talk about significant others J Psychopharmacol. 2015 Jun; 29(6):669-77. . View in PubMed
• MDMA: a social drug in a social context Psychopharmacology (Berl). 2015 Mar; 232(6):1155-63. . View in PubMed
• Examination of anxiety sensitivity and distress tolerance as transdiagnostic mechanisms linking multiple anxiety pathologies to alcohol use problems in adolescents Alcohol Clin Exp Res. 2015 Mar; 39(3):532-9. . View in PubMed
• MDMA effects consistent across laboratories Psychopharmacology (Berl). 2014 Oct; 231(19):3899-905. . View in PubMed
• Plasma oxytocin concentrations following MDMA or intranasal oxytocin in humans Psychoneuroendocrinology. 2014 Aug; 46:23-31. . View in PubMed
• ‘Ecstasy’ as a social drug: MDMA preferentially affects responses to emotional stimuli with social content Soc Cogn Affect Neurosci. 2014 Aug; 9(8):1076-81. . View in PubMed
• Effects of MDMA and Intranasal oxytocin on social and emotional processing Neuropsychopharmacology. 2014 Jun; 39(7):1654-63. . View in PubMed
• In the company of others: social factors alter acute alcohol effects Psychopharmacology (Berl). 2013 Nov; 230(2):215-26. . View in PubMed
• Intranasal substituted cathinone “bath salts” psychosis potentially exacerbated by diphenhydramine J Addict Med. 2013 May-Jun; 7(3):163-8. . View in PubMed
• Personality and the acute subjective effects of d-amphetamine in humans J Psychopharmacol. 2013 Mar; 27(3):256-64. . View in PubMed
• Comparison of intranasal methamphetamine and d-amphetamine self-administration by humans Addiction. 2012 Apr; 107(4):783-91. . View in PubMed
• Acute and residual interactive effects of repeated administrations of oral methamphetamine and alcohol in humans Psychopharmacology (Berl). 2012 Jan; 219(1):191-204. . View in PubMed
• A direct comparison of the behavioral and physiological effects of methamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) in humans Psychopharmacology (Berl). 2012 Jan; 219(1):109-22. . View in PubMed
• Zolpidem does not serve as reinforcer in humans subjected to simulated shift work Drug Alcohol Depend. 2010 Nov 01; 112(1-2):168-71. . View in PubMed
• Methamphetamine self-administration by humans subjected to abrupt shift and sleep schedule changes Psychopharmacology (Berl). 2009 May; 203(4):771-80. . View in PubMed
• Acute physiological and behavioral effects of intranasal methamphetamine in humans Neuropsychopharmacology. 2008 Jul; 33(8):1847-55. . View in PubMed
• Residual effects of intranasal methamphetamine on sleep, mood, and performance Drug Alcohol Depend. 2008 Apr 01; 94(1-3):258-62. . View in PubMed
• Effects of intranasal methamphetamine on metacognition of agency Psychopharmacology (Berl). 2008 Mar; 197(1):137-44. . View in PubMed

• Leventhal, Adam
• Barrington-Trimis, Jessica
• Unger, Jennifer
• Allem, Jon
• Sussman, Steven
• Lerman, Caryn
• Pang, Raina
• McConnell, Rob
• Pentz, Maryann
• Harlow, Alyssa