Alexandra Kovach, MD

Associate Professor of Clinical Pathology

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Publications

  • Development of second genetically distinct T-lymphoblastic leukemia in a pediatric patient Pediatr Blood Cancer. 2024 Aug; 71(8):e31050. . View in PubMed
  • IKZF1PLUS alterations contribute to outcome disparities in Hispanic/Latino children with B-lymphoblastic leukemia Pediatr Blood Cancer. 2024 Jul; 71(7):e30996. . View in PubMed
  • A de novo germline RUNX1 variant preceding development of concurrent T-lymphoblastic leukemia and myelodysplastic syndrome Leuk Lymphoma. 2024 May 11; 1-5. . View in PubMed
  • An Exome Capture-Based RNA-Sequencing Assay for Genome-Wide Identification and Prioritization of Clinically Important Fusions in Pediatric Tumors J Mol Diagn. 2024 Feb; 26(2):127-139. . View in PubMed
  • Maturational dyssynchrony in benign B-cell precursors following lymphocyte depleting chemotherapy: A potential pitfall for B-lymphoblastic leukemia minimal/measurable residual disease (MRD) flow cytometry analysis Cytometry B Clin Cytom. 2024 03; 106(2):138-141. . View in PubMed
  • Concordance of Next-Generation Sequencing and Multiparametric Flow Cytometry Methods for Detecting Measurable Residual Disease in Adult Acute Lymphoblastic Leukemia: Optimizing Prediction of Clinical Outcomes From a Single-Center StudyClin Lymphoma Myeloma Leuk. 2024 03; 24(3):e59-e66. e2. . View in PubMed
  • Transcriptome Sequencing Allows Comprehensive Genomic Characterization of Pediatric B-Acute Lymphoblastic Leukemia in an Academic Clinical Laboratory J Mol Diagn. 2024 Jan; 26(1):49-60. . View in PubMed
  • B-cell acute lymphoblastic leukemia and juvenile xanthogranuloma in a patient with ETV6 thrombocytopenia and leukemia predisposition syndrome: novel clinical presentation and perspective Haematologica. 2023 Nov 30. . View in PubMed
  • Updates on lymphoblastic leukemia/lymphoma classification and minimal/measurable residual disease analysis Semin Diagn Pathol. 2023 Nov; 40(6):457-471. . View in PubMed
  • Correction: “The 5th edition of The World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms” Leukemia2022 Jul;36(7):1720-1748. Leukemia. 2023 Sep; 37(9):1944-1951. . View in PubMed
  • Significant Variability in the Identification and Reporting of Band Neutrophils by Participants Enrolled in the College of American Pathologists Proficiency Testing Program: Time for a Change Arch Pathol Lab Med. 2023 Aug 28. . View in PubMed
  • Spontaneous remission of acute lymphoblastic leukemia: A series of nine cases and a review of literature Int J Lab Hematol. 2023 Aug; 45(4):489-495. . View in PubMed
  • Modern Classification and Management of Pediatric B-cell Leukemia and Lymphoma Surg Pathol Clin. 2023 Jun; 16(2):249-266. . View in PubMed
  • Efficacy and safety of FLAG-IDA as front-line therapy in de novo paediatric acute myeloid leukaemia population Br J Haematol. 2023 07; 202(1):e3-e6. . View in PubMed
  • Preinfusion factors impacting relapse immunophenotype following CD19 CAR T cells Blood Adv. 2023 02 28; 7(4):575-585. . View in PubMed
  • Outcomes of patients with blastoid and pleomorphic variant mantle cell lymphoma Blood Adv. 2023 12 26; 7(24):7393-7401. . View in PubMed
  • Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Sternberg Cells Blood Cancer Discov. 2023 05 01; 4(3):208-227. . View in PubMed
  • The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms Leukemia. 2022 07; 36(7):1720-1748. . View in PubMed
  • Survival of pediatric Hodgkin lymphoma patients treated with doxorubicin, bleomycin, vincristine, etoposide, prednisone, and cyclophosphamide (ABVE-PC) versus doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) at a single institution Pediatr Blood Cancer. 2022 05; 69(5):e29601. . View in PubMed
  • Acute myeloid leukemia with t(X;6)9p11;q23);MYB-GATA1 and female sex: GATA1 insufficiency may be insufficient for pathogenesis Cancer Genet. 2022 01; 260-261:37-40. . View in PubMed
  • Blinatumomab Nonresponse and High-Disease Burden Are Associated With Inferior Outcomes After CD19-CAR for B-ALL J Clin Oncol. 2022 03 20; 40(9):932-944. . View in PubMed
  • Characterization of PAX5 intragenic tandem multiplication in pediatric B-lymphoblastic leukemia by optical genome mapping Blood Adv. 2022 06 14; 6(11):3343-3346. . View in PubMed
  • Pediatric hematolymphoid pathology in the gastrointestinal tract Semin Diagn Pathol. 2021 Jul; 38(4):31-37. . View in PubMed
  • BCR-ABL1-like B-Lymphoblastic Leukemia/Lymphoma with FOXP1-ABL1 Rearrangement: Comprehensive Laboratory Identification Allowing Tyrosine Kinase Inhibitor Use Lab Med. 2019 Oct 10; 50(4):401-405. . View in PubMed
  • Ectopic Fetal Hepatic Tissue in the Placenta Int J Gynecol Pathol. 2019 Sep; 38(5):426-429. . View in PubMed
  • Molecular and Cytogenetic Education in Hematopathology Fellowship Am J Clin Pathol. 2019 09 09; 152(4):438-445. . View in PubMed
  • R-CHOP versus dose-adjusted R-EPOCH in frontline management of primary mediastinal B-cell lymphoma: a multi-centre analysis Br J Haematol. 2018 02; 180(4):534-544. . View in PubMed
  • Fibrin-associated EBV-positive Large B-Cell Lymphoma: An Indolent Neoplasm With Features Distinct From Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation Am J Surg Pathol. 2017 Mar; 41(3):299-312. . View in PubMed
  • Prognostic Significance of Residual Acute Myeloid Leukemia in Bone Marrow Samples Taken Prior to Allogeneic Hematopoietic Cell Transplantation Am J Clin Pathol. 2017 Jan 01; 147(1):50-59. . View in PubMed
  • Diffuse large B-cell lymphoma with concurrent high MYC and BCL2 expression shows evidence of active B-cell receptor signaling by quantitative immunofluorescence PLoS One. 2017; 12(2):e0172364. . View in PubMed
  • Can computed tomography distinguish thymoma, lymphoma, thymic hyperplasia, and thymic cysts? Eur J Radiol. 2015 Mar; 84(3):524-533.. View in PubMed
  • Molecular classification of MYC-driven B-cell lymphomas by targeted gene expression profiling of fixed biopsy specimens J Mol Diagn. 2015 Jan; 17(1):19-30. . View in PubMed