Keck School Faculty

April W. Armstrong

April W. Armstrong

Professor of Dermatology (Clinical Scholar)
Associate Dean for Clinical Research
HC4 2000 1450 San Pablo Health Sciences Campus Los Angeles

International League of Dermatological Societies (ILDS): International Achievement Award, 2014

American Academy of Dermatology: President’s Award for Volunteerism in Telemedicine, 2011

Agency for Healthcare Research and Quality (AHRQ) : K08 Mentored Career Development Award, 2009-2013

Dermatology Foundation: Career Development Award in Health Care Policy , 2009

Women's Dermatologic Society: Academic Research Award, 2009

University of California Davis (funded through NIH): K12 Mentored Career Development Award, 2009

21st World Congress of Dermatology: Outstanding Clinical Research Award, 2007

American Telemedicine Association: Innovative Research Award in Teledermatology, 2006-2008

Harvard Medical School : Richard C. Cabot Prize for Excellence in Medical Education, 2004

Dupilumab improves patient-reported symptoms of atopic dermatitis, symptoms of anxiety and depression, and health-related quality of life in moderate-to-severe atopic dermatitis: analysis of pooled data from the randomized trials SOLO 1 and SOLO 2 J Dermatolog Treat. 2020 Sep; 31(6):606-614. . View in PubMed

A Randomized Placebo-Controlled Trial of Secukinumab on Aortic Vascular Inflammation in Moderate-to-Severe Plaque Psoriasis (VIP-S)J Invest Dermatol. 2020 Sep; 140(9):1784-1793. e2. . View in PubMed

Development of the Psoriasis Symptoms Scale (PSS) in patients with moderate-to-severe psoriasis: qualitative and quantitative analyses J Dermatolog Treat. 2020 Aug; 31(5):452-459. . View in PubMed

Brodalumab to the Rescue: Efficacy and Safety of Brodalumab in Patients with Psoriasis and Prior Exposure or Inadequate Response to Biologics Dermatol Ther (Heidelb). 2020 Aug; 10(4):615-621. . View in PubMed

Association Between the Mental Health of Patients With Psoriasis and Their Satisfaction With Physicians JAMA Dermatol. 2020 Jul 01; 156(7):754-762. . View in PubMed

Cost-effectiveness of tildrakizumab for the treatment of moderate-to-severe psoriasis in the United States J Dermatolog Treat. 2020 Jun 30; 1-9. . View in PubMed

Comparison of 2-Octylcyanoacrylate Versus 5-0 Fast-Absorbing Gut During Linear Wound Closures and the Effect on Wound Cosmesis Dermatol Surg. 2020 May; 46(5):628-634. . View in PubMed

Efficacy and Safety of Lebrikizumab, a High-Affinity Interleukin 13 Inhibitor, in Adults With Moderate to Severe Atopic Dermatitis: A Phase 2b Randomized Clinical Trial JAMA Dermatol. 2020 Apr 01; 156(4):411-420. . View in PubMed

Comparative cost-effectiveness of tildrakizumab and other commonly used treatments for moderate-to-severe psoriasis J Dermatolog Treat. 2020 Apr 01; 1-8. . View in PubMed

Dermatologists in social media: A study on top influencers, posts, and user engagement J Am Acad Dermatol. 2020 Mar 07. . View in PubMed

Comparison of Biologics and Oral Treatments for Plaque Psoriasis: A Meta-analysis JAMA Dermatol. 2020 Feb 05. . View in PubMed

Dermal suture only versus layered closure: A randomized, split wound comparative effectiveness trial J Am Acad Dermatol. 2019 Dec; 81(6):1346-1352. . View in PubMed

Differences in wage earnings between psoriasis patients on biologics versus those on oral therapies: a population-based study in the United States J Dermatolog Treat. 2019 Oct 10; 1-6. . View in PubMed

Achievement of the National Psoriasis Foundation Treatment Targets With Ixekizumab: Pooled Analyses From Four Clinical Studies J Am Acad Dermatol. 2019 Sep 25. . View in PubMed

Association between atopic dermatitis and conjunctivitis in adults: a population-based study in the United States J Dermatolog Treat. 2019 Sep 02; 1-5. . View in PubMed

J Dermatolog Treat. 2019 Sep 02; 1-7. . View in PubMed

Comparison of physical and mental functioning among moderate-to-severe psoriasis patients on biologic versus oral therapy Arch Dermatol Res. 2019 Aug; 311(6):453-460. . View in PubMed

An unusual spiculated presentation of follicular porokeratosis Dermatol Online J. 2019 Jul 15; 25(7). . View in PubMed

Effects of Online Care on Functional and Psychological Outcomes in Patients with Psoriasis: A Randomized Controlled Trial J Am Acad Dermatol. 2019 Jun 05. . View in PubMed

Economic burden of cutaneous infections in children and adults with atopic dermatitis Pediatr Dermatol. 2019 May; 36(3):303-310. . View in PubMed

Comparison of mental health outcomes among adults with psoriasis on biologic versus oral therapies: a population-based study J Dermatolog Treat. 2019 Mar; 30(2):135-140. . View in PubMed

Access to Dermatological Care with an Innovative Online Model for Psoriasis Management: Results from a Randomized Controlled Trial Telemed J E Health. 2019 07; 25(7):619-627. . View in PubMed

Anti-tumor necrosis factor agents in sarcoidosis: A systematic review of efficacy and safety Semin Arthritis Rheum. 2019 06; 48(6):1093-1104. . View in PubMed

Assessing Skin Biopsy Rates for Histologic Findings Indicative of Nonpathological Cutaneous Disease Dermatol Surg. 2019 05; 45(5):640-649. . View in PubMed

A provider global assessment quality measure for clinical practice for inflammatory skin disorders J Am Acad Dermatol. 2019 03; 80(3):823-828. . View in PubMed

Association Between Atopic Dermatitis and Suicidality: A Systematic Review and Meta-analysis JAMA Dermatol. 2019 02 01; 155(2):178-187. . View in PubMed

Comparison of Running Cutaneous Suture Spacing During Linear Wound Closures and the Effect on Wound Cosmesis of the Face and Neck: A Randomized Clinical Trial JAMA Dermatol. 2019 03 01; 155(3):321-326. . View in PubMed

Effect of Age of Onset of Psoriasis on Clinical Outcomes with Systemic Treatment in the Psoriasis Longitudinal Assessment and Registry (PSOLAR) Am J Clin Dermatol. 2018 Dec; 19(6):879-886. . View in PubMed

Achieving international consensus on the assessment of psoriatic arthritis in psoriasis clinical trials: an International Dermatology Outcome Measures (IDEOM) initiative Arch Dermatol Res. 2018 Nov; 310(9):701-710. . View in PubMed

J Dermatolog Treat. 2018 May; 29(3):295-299. . View in PubMed

Common and Not-So-Common Comorbidities of Psoriasis Semin Cutan Med Surg. 2018 Feb; 37(2S):S48-S51. . View in PubMed

Effect of 2 Psoriasis Treatments on Vascular Inflammation and Novel Inflammatory Cardiovascular Biomarkers: A Randomized Placebo-Controlled Trial Circ Cardiovasc Imaging. 2018 06; 11(6):e007394. . View in PubMed

Adverse Medical Conditions Across Treatment Options in Patients With Psoriasis: A Claims-Based Analysis J Drugs Dermatol 2018 11 01; 17(11):1211-1218. . View in PubMed

Are Your Patients Satisfied A Systematic Review of Treatment Satisfaction Measures in Psoriasis Dermatology. 2018; 234(5-6):157-165. . View in PubMed

Dietary Recommendations for Adults With Psoriasis or Psoriatic Arthritis From the Medical Board of the National Psoriasis Foundation: A Systematic Review JAMA Dermatol. 2018 08 01; 154(8):934-950. . View in PubMed

Characteristics of Medical Liability Claims Against Dermatologists From 1991 Through 2015 JAMA Dermatol. 2018 02 01; 154(2):160-166. . View in PubMed

Effectiveness of Online vs In-Person Care for Adults With Psoriasis: A Randomized Clinical Trial JAMA Netw Open. 2018 10 05; 1(6):e183062. . View in PubMed

Development and psychometric evaluation of the self-assessment of psoriasis symptoms (SAPS) - clinical trial and the SAPS - real world patient-reported outcomes J Dermatolog Treat. 2017 Sep; 28(6):505-514. . View in PubMed

Drivers of Healthcare Costs Among the Costliest Patients With Psoriasis Over Three Years in a United States Health Plan J Drugs Dermatol. 2017 Jul 01; 16(7):651-658. . View in PubMed

Assessing the overall benefit of a medication: cumulative benefit of secukinumab over time in patients with moderate-to-severe plaque psoriasis J Dermatolog Treat. 2017 May; 28(3):200-205. . View in PubMed

Efficacy and safety of guselkumab, an anti-interleukin-23 monoclonal antibody, compared with adalimumab for the treatment of patients with moderate to severe psoriasis with randomized withdrawal and retreatment: Results from the phase III, double-blind, placebo- and active comparator-controlled VOYAGE 2 trial J Am Acad Dermatol. 2017 Mar; 76(3):418-431. . View in PubMed

Direct-Access Online Care for the Management of Atopic Dermatitis: A Randomized Clinical Trial Examining Patient Quality of Life Telemed J E Health. 2017 09; 23(9):726-732. . View in PubMed

Defining Outcome Measures for Psoriasis: The IDEOM Report from the GRAPPA 2016 Annual Meeting J Rheumatol. 2017 05; 44(5):701-702. . View in PubMed

Benchmarking Care in Psoriatic Arthritis - The QUANTUM Report: A Report from the GRAPPA 2016 Annual Meeting J Rheumatol. 2017 05; 44(5):674-678. . View in PubMed

An update on psoriasis and metabolic syndrome: A meta-analysis of observational studies PLoS One. 2017; 12(7):e0181039. . View in PubMed

Antibiotic Resistance in Acne Treatment JAMA Dermatol. 2017 08 01; 153(8):810-811. . View in PubMed

Body Region Involvement and Quality of Life in Psoriasis: Analysis of a Randomized Controlled Trial of Adalimumab Am J Clin Dermatol. 2016 Dec; 17(6):691-699. . View in PubMed

Effect of a Pre-Treatment Educational Video in Improving Patient Satisfaction with 5-Fluorouracil Treatment for Actinic Keratoses: A Randomized Controlled Trial Dermatol Ther (Heidelb). 2016 Dec; 6(4):675-681. . View in PubMed

Adalimumab Treatment in Women With Moderate-to-Severe Hidradenitis Suppurativa from the Placebo-Controlled Portion of a Phase 2, Randomized, Double-Blind Study J Drugs Dermatol. 2016 Oct 01; 15(10):1192-1196. . View in PubMed

Comparative efficacy and incremental cost per responder of methotrexate versus apremilast for methotrexate-naïve patients with psoriasis J Am Acad Dermatol. 2016 Oct; 75(4):740-746. . View in PubMed

A Clinician's Guide to the Diagnosis and Treatment of Candidiasis in Patients with Psoriasis Am J Clin Dermatol. 2016 Aug; 17(4):329-36. . View in PubMed

Adalimumab Efficacy in Patients with Psoriasis Who Received or Did Not Respond to Prior Systemic Therapy: A Pooled Post Hoc Analysis of Results from Three Double-Blind, Placebo-Controlled Clinical Trials Am J Clin Dermatol. 2016 Feb; 17(1):79-86. . View in PubMed

Effect of Ixekizumab Treatment on Work Productivity for Patients With Moderate-to-Severe Plaque Psoriasis: Analysis of Results From 3 Randomized Phase 3 Clinical Trials JAMA Dermatol. 2016 06 01; 152(6):661-9. . View in PubMed

Dietary supplementation with Bifidobacterium longum subspinfantis (B. infantis) in healthy breastfed infants: study protocol for a randomised controlled trial. Trials. 2016 07 22; 17(1):340. . View in PubMed

A case of Kaposi sarcoma in an immunocompetent, heterosexual Irish man: a discussion of etiology and viral transmission Dermatol Online J. 2015 Oct 16; 21(10). . View in PubMed

Effectiveness of a novel interactive health care education tool on clinical outcomes and quality of life in acne patients: A randomized controlled pilot study J Dermatolog Treat. 2015 Oct; 26(5):435-9. . View in PubMed

Comparing cutaneous research funded by the US National Institutes of Health (NIH) with the US skin disease burdenJ Am Acad Dermatol. 2015 Sep; 73(3):383-91. e1. . View in PubMed

Effect of Automated Online Counseling on Clinical Outcomes and Quality of Life Among Adolescents With Acne Vulgaris: A Randomized Clinical Trial JAMA Dermatol. 2015 Sep; 151(9):970-5. . View in PubMed

Effect of Adhesive Strips and Dermal Sutures vs Dermal Sutures Only on Wound Closure: A Randomized Clinical Trial JAMA Dermatol. 2015 Aug; 151(8):862-7. . View in PubMed

Int J Dermatol. 2015 Jul; 54(7):807-16. . View in PubMed

Economic Burden of Psoriasis in the United States: A Systematic Review JAMA Dermatol. 2015 Jun; 151(6):651-8. . View in PubMed

Combining biologic therapies with other systemic treatments in psoriasis: evidence-based, best-practice recommendations from the Medical Board of the National Psoriasis Foundation JAMA Dermatol. 2015 Apr; 151(4):432-8. . View in PubMed

Effect of tonsillectomy on psoriasis: a systematic review J Am Acad Dermatol. 2015 Feb; 72(2):261-75. . View in PubMed

Comparing the effectiveness of automated online counseling to standard web-based education on improving acne knowledge: a randomized controlled trial Am J Clin Dermatol. 2015 Feb; 16(1):55-60. . View in PubMed

An evidence-based review of the mechanism of action, efficacy, and safety of biologic therapies in the treatment of psoriasis and psoriatic arthritis Curr Med Chem. 2015; 22(16):1930-42. . View in PubMed

Efficacy of photodynamic therapy vs other interventions in randomized clinical trials for the treatment of actinic keratoses: a systematic review and meta-analysis JAMA Dermatol. 2014 Dec; 150(12):1281-8. . View in PubMed

Comparative prevalence of complementary and alternative medicine use among outpatients in dermatology and primary care clinics JAMA Dermatol. 2014 Dec; 150(12):1363-5. . View in PubMed

Effect of appearance-based education compared with health-based education on sunscreen use and knowledge: a randomized controlled trial J Am Acad Dermatol. 2014 Apr; 70(4):665-669. . View in PubMed

Diet and nutrition in psoriasis: analysis of the National Health and Nutrition Examination Survey (NHANES) in the United States J Eur Acad Dermatol Venereol. 2014 Mar; 28(3):327-32. . View in PubMed

Antidrug antibodies in psoriasis: a systematic review Br J Dermatol. 2014 Feb; 170(2):261-73. . View in PubMed

Effects of biologic agents and other disease-modifying antirheumatic drugs on cardiovascular outcomes in psoriasis and psoriatic arthritis: a systematic review Curr Pharm Des. 2014; 20(4):500-12. . View in PubMed

Association between psoriasis and viral infections in the United States: focusing on hepatitis B, hepatitis C and human immunodeficiency virus J Eur Acad Dermatol Venereol. 2013 Oct; 27(10):1312-6. . View in PubMed

Anti-drug antibodies in psoriasis: a critical evaluation of clinical significance and impact on treatment response Expert Rev Clin Immunol. 2013 Oct; 9(10):949-58. . View in PubMed

Corticosteroids and wound healing: clinical considerations in the perioperative period Am J Surg. 2013 Sep; 206(3):410-7. . View in PubMed

Cardiovascular comorbidities of psoriasis and psoriatic arthritis: a report from the GRAPPA 2012 annual meeting J Rheumatol. 2013 Aug; 40(8):1434-7. . View in PubMed

Clinical manifestations of pediatric psoriasis: results of a multicenter study in the United States Pediatr Dermatol. 2013 Jul-Aug; 30(4):424-8. . View in PubMed

Access to health care in patients with psoriasis and psoriatic arthritis: data from National Psoriasis Foundation survey panels JAMA Dermatol. 2013 Jun; 149(6):717-21. . View in PubMed

Do TNF inhibitors reduce the risk of myocardial infarction in psoriasis patients? JAMA. 2013 May 15; 309(19):2043-4.. View in PubMed

Clinical and histologic diagnostic guidelines for psoriasis: a critical review Clin Rev Allergy Immunol. 2013 Apr; 44(2):166-72. . View in PubMed

Effect of nutrient supplementation on atopic dermatitis in children: a systematic review of probiotics, prebiotics, formula, and fatty acids JAMA Dermatol. 2013 Mar; 149(3):350-5. . View in PubMed

Crowdsourcing for data collection: a pilot study comparing patient-reported experiences and clinical trial data for the treatment of seborrheic dermatitis Skin Res Technol. 2013 Feb; 19(1):55-7. . View in PubMed

J Am Acad Dermatol. 2012 Dec; 67(6):1136-42. . View in PubMed

Congenital self-healing reticulohistiocytosis: concern for a poor prognosis Dermatol Online J. 2012 Oct 15; 18(10):2. . View in PubMed

Application of mobile teledermatology for skin cancer screening J Am Acad Dermatol. 2012 Oct; 67(4):576-81. . View in PubMed

Crowdsourcing in eczema research: a novel method of data collection J Drugs Dermatol. 2012 Oct; 11(10):1153-5. . View in PubMed

J Am Acad Dermatol. 2012 Sep; 67(3):357-62. . View in PubMed

Coronary artery disease in patients with psoriasis referred for coronary angiography Am J Cardiol. 2012 Apr 01; 109(7):976-80. . View in PubMed

Cost-effectiveness analysis of a patient-centered care model for management of psoriasis J Am Acad Dermatol. 2012 Apr; 66(4):563-70. . View in PubMed

Combination treatments for psoriasis: a systematic review and meta-analysis Arch Dermatol. 2012 Apr; 148(4):511-22. . View in PubMed

Crowdsourcing for research data collection in rosacea Dermatol Online J. 2012 Mar 15; 18(3):15. . View in PubMed

Advances in management of atopic dermatitis: new therapies and novel uses of existing treatments Semin Cutan Med Surg. 2012 Mar; 31(1):17-24. . View in PubMed

A review of health outcomes in patients with psoriasis Dermatol Clin. 2012 Jan; 30(1):61-72viii. . View in PubMed

Combination systemic therapies in psoriatic arthritis J Dermatolog Treat. 2011 Oct; 22(5):276-84. . View in PubMed

Angiogenesis and oxidative stress: common mechanisms linking psoriasis with atherosclerosis J Dermatol Sci. 2011 Jul; 63(1):1-9. . View in PubMed

Effects of video-based, online education on behavioral and knowledge outcomes in sunscreen use: a randomized controlled trial Patient Educ Couns. 2011 May; 83(2):273-7. . View in PubMed

Current state of acne treatment: highlighting lasers, photodynamic therapy, and chemical peels Dermatol Online J. 2011 Mar 15; 17(3):2. . View in PubMed

A pale version Am J Med. 2010 Sep; 123(9):802-4. . View in PubMed

A national survey to determine an optimal fourth year curriculum for dermatology candidates Dermatol Online J. 2009 Oct 15; 15(10):2. . View in PubMed

Digital imaging in dermatology: attitudes, behaviors, and innovations Skin Res Technol. 2009 Aug; 15(3):376-7. . View in PubMed

Economic evaluation of interactive teledermatology compared with conventional care Telemed J E Health. 2007 Apr; 13(2):91-9. . View in PubMed

Please visit Dr. Armstrong's research website:

Dr. April Armstrong is Associate Dean of Clinical Research at Keck School of Medicine at USC. She also serves as Director of Clinical Research for the Southern California Clinical and Translational Research Institute (SC CTSI). In the Department of Dermatology at USC, she serves as Vice Chair, Director of Clinical Trials and Outcomes Research, and Director of the Psoriasis Program.

Dr. Armstrong obtained her medical degree from Harvard Medical School and completed dermatology residency at the Harvard Dermatology Residency Program. She also obtained a Master of Public Health degree from Harvard School of Public Health. Prior to joining faculty at the University of Southern California, Dr. Armstrong served as Vice Chair, Director of Clinical Research, and Director of Psoriasis Program at dermatology departments at the University of California Davis and later at the University of Colorado.

For her research focus, Dr. Armstrong is particularly interested in the appropriate use of systemic agents, comparative effectiveness research, technology-enabled healthcare delivery, and comorbidities associated with inflammatory skin diseases. Dr. Armstrong has conducted studies examining how new therapies impact patients’ disease states, quality of life, and their access to medical care. She is also examining how technology-enabled healthcare delivery can be applied to manage patients with chronic dermatological diseases. She is a federally funded investigator with an extensive clinical trial experience, having led or collaborated on over 120 studies. She has authored over 150 peer-reviewed scientific publications and has been an editor for the top pharmacology textbook Principles of Pharmacology. Her work has been supported by the NIH, Patient-Centered Outcomes Research Institute (PCORI), the Agency for Healthcare Research and Quality (AHRQ), the Dermatology Foundation, and the National Psoriasis Foundation.

Dr. Armstrong has held multiple leadership positions at professional societies, serving as a Medical Board of the National Psoriasis Foundation, Councilor to the International Psoriasis Council, Steering Committee Member for Group for Research and Assessment of Psoriasis and Psoriatic Arthritis. Dr. Armstrong is Chair for Teledermatology SIG at the American Telemedicine Association. She also has served on multiple task forces and committees at the American Academy of Dermatology. Dr. Armstrong also has also served on the editorial boards of JAMA Dermatology, Journal of the American Academy of Dermatology, and Telemedicine and eHealth. She was also past President of Sacramento Valley Dermatologic Society.
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