Keck School Faculty

Ararat Chakhoyan

Ararat Chakhoyan

Assistant Professor of Research Physiology & Neuroscience
Medicine
1501 San Pablo St. Health Sciences Campus Los Angeles

Editorial for "MRI-Based Investigation of Association Between Cerebrovascular Structural Alteration and White Matter Hyperintensity Induced by High Blood Pressure" J Magn Reson Imaging. 2021 11; 54(5):1527-1528. . View in PubMed

Simultaneous Mapping of Vasculature, Hypoxia, and Proliferation Using Dynamic Susceptibility Contrast MRI, 18F-FMISO PET, and 18F-FLT PET in Relation to Contrast Enhancement in Newly Diagnosed Glioblastoma J Nucl Med. 2021 10; 62(10):1349-1356. . View in PubMed

APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline Nature. 2020 05; 581(7806):71-76. . View in PubMed

Multiparametric MR-PET Imaging Predicts Pharmacokinetics and Clinical Response to GDC-0084 in Patients with Recurrent High-Grade Glioma Clin Cancer Res. 2020 07 01; 26(13):3135-3144. . View in PubMed

pH-weighted amine chemical exchange saturation transfer echoplanar imaging (CEST-EPI) as a potential early biomarker for bevacizumab failure in recurrent glioblastoma J Neurooncol. 2019 May; 142(3):587-595. . View in PubMed

Probabilistic independent component analysis of dynamic susceptibility contrast perfusion MRI in metastatic brain tumors Cancer Imaging. 2019 Mar 18; 19(1):14. . View in PubMed

Association between Tumor Acidity and Hypervascularity in Human Gliomas Using pH-Weighted Amine Chemical Exchange Saturation Transfer Echo-Planar Imaging and Dynamic Susceptibility Contrast Perfusion MRI at 3T AJNR Am J Neuroradiol. 2019 06; 40(6):979-986. . View in PubMed

pH-weighted molecular MRI in human traumatic brain injury (TBI) using amine proton chemical exchange saturation transfer echoplanar imaging (CEST EPI) Neuroimage Clin. 2019; 22:101736. . View in PubMed

Validation of vessel size imaging (VSI) in high-grade human gliomas using magnetic resonance imaging, image-guided biopsies, and quantitative immunohistochemistry Sci Rep. 2019 02 26; 9(1):2846. . View in PubMed

Metabolic characterization of human IDH mutant and wild type gliomas using simultaneous pH- and oxygen-sensitive molecular MRI Neuro Oncol. 2019 09 06; 21(9):1184-1196. . View in PubMed

18F-FDOPA PET and MRI characteristics correlate with degree of malignancy and predict survival in treatment-naïve gliomas: a cross-sectional study J Neurooncol. 2018 Sep; 139(2):399-409. . View in PubMed

Mono-exponential, diffusion kurtosis and stretched exponential diffusion MR imaging response to chemoradiation in newly diagnosed glioblastoma J Neurooncol. 2018 Sep; 139(3):651-659. . View in PubMed

Simultaneous pH-sensitive and oxygen-sensitive MRI of human gliomas at 3 T using multi-echo amine proton chemical exchange saturation transfer spin-and-gradient echo echo-planar imaging (CEST-SAGE-EPI) Magn Reson Med. 2018 11; 80(5):1962-1978. . View in PubMed

Improved Spatiotemporal Resolution of Dynamic Susceptibility Contrast Perfusion MRI in Brain Tumors Using Simultaneous Multi-Slice Echo-Planar Imaging AJNR Am J Neuroradiol. 2018 01; 39(1):43-45. . View in PubMed

Post-chemoradiation volumetric response predicts survival in newly diagnosed glioblastoma treated with radiation, temozolomide, and bevacizumab or placebo Neuro Oncol. 2018 10 09; 20(11):1525-1535. . View in PubMed

Volumetric response quantified using T1 subtraction predicts long-term survival benefit from cabozantinib monotherapy in recurrent glioblastoma Neuro Oncol. 2018 09 03; 20(10):1411-1418. . View in PubMed

Diffusion MRI Phenotypes Predict Overall Survival Benefit from Anti-VEGF Monotherapy in Recurrent Glioblastoma: Converging Evidence from Phase II Trials Clin Cancer Res. 2017 Oct 01; 23(19):5745-5756. . View in PubMed

Imaging of brain oxygenation with magnetic resonance imaging: A validation with positron emission tomography in the healthy and tumoural brain J Cereb Blood Flow Metab. 2017 Jul; 37(7):2584-2597. . View in PubMed

Carbogen-induced increases in tumor oxygenation depend on the vascular status of the tumor: A multiparametric MRI study in two rat glioblastoma models J Cereb Blood Flow Metab. 2017 Jun; 37(6):2270-2282. . View in PubMed

FMISO-PET-derived brain oxygen tension maps: application to glioblastoma and less aggressive gliomas Sci Rep. 2017 08 31; 7(1):10210. . View in PubMed

Imaging Modalities to Assess Oxygen Status in Glioblastoma Front Med (Lausanne). 2015; 2:57. . View in PubMed

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