Keck School Faculty

Edward Lawrence Avol, MS
Edward Lawrence Avol, MS
Professor of Clinical Preventive Medicine;Division Chief, Environmental Health
Environmental Health
SSB 230C 2001 N. Soto Street Health Sciences Campus Los Angeles
Ed Avol is Professor of Clinical Preventive Medicine, with expertise in exposure assessment and acute/chronic respiratory and cardiovascular effects of airborne pollutants in populations at risk (including children, athletes, and subjects with compromised lung function). He was the Deputy Director of the Children's Health Study and is a key investigator in multiple ongoing investigations of the effects of environmental exposures on human health. He is the Director of the Spatial Exposure and Analytics Core (SEAC) in the NIEHS-supported Southern California Environmental Health Sciences Center, Director of the Population Resources Core of the FDA-sponsored Tobacco Research Center, and is a co-investigator on several NIH and regional studies to assess the association of air pollution with children's respiratory health. Professor Avol both teaches in and leads the undergraduate Environmental Health teaching track through the Health Promotion program at USC. He is also actively involved in community outreach efforts, particularly with regard to health and air quality issues associated with Los Angeles/Long Beach seaport operations and expansions.

Near-roadway air pollution exposure and altered fatty acid oxidation among adolescents and young adults - The interplay with obesity Environ Int. 2019 Jun 22; 130:104935. . View in PubMed

RISK EFFECTS OF NEAR-ROADWAY POLLUTANTS AND ASTHMA STATUS ON BRONCHITIC SYMPTOMS IN CHILDREN Environ Epidemiol. 2018 Jun; 2(2). . View in PubMed

Association of Changes in Air Quality With Bronchitic Symptoms in Children in California, 1993-2012 JAMA. 2016 Apr 12; 315(14):1491-501. . View in PubMed

Prenatal Air Pollution Exposures, DNA Methyl Transferase Genotypes, and Associations with Newborn LINE1 and Alu Methylation and Childhood Blood Pressure and Carotid Intima-Media Thickness in the Children's Health Study Environ Health Perspect. 2016 12; 124(12):1905-1912. . View in PubMed

Prenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults PLoS One. 2016; 11(3):e0150825. . View in PubMed

Association of improved air quality with lung development in children N Engl J Med. 2015 Mar 05; 372(10):905-13. . View in PubMed

Emissions reduction policies and recent trends in Southern California's ambient air quality J Air Waste Manag Assoc. 2015 Mar; 65(3):324-35. . View in PubMed

Could environmental exposures facilitate the incidence of addictive behaviors? Eval Health Prof. 2015 Mar; 38(1):53-8.. View in PubMed

Associations of children's lung function with ambient air pollution: joint effects of regional and near-roadway pollutants Thorax. 2014 Jun; 69(6):540-7. . View in PubMed

NOS1 methylation and carotid artery intima-media thickness in children Circ Cardiovasc Genet. 2014 Apr; 7(2):116-22. . View in PubMed

HDL anti-oxidant function associates with LDL level in young adults Atherosclerosis. 2014 Jan; 232(1):165-70. . View in PubMed

Response to letter regarding article, “Childhood air pollutant exposure and carotid artery intima–media thickness in young adults” Circulation. 2013 Jun 04; 127(22):e659. . View in PubMed

Birth weight and carotid artery intima-media thicknessJ Pediatr. 2013 May; 162(5):906-11. e1-2. . View in PubMed

Development of a regional-scale pollen emission and transport modeling framework for investigating the impact of climate change on allergic airway disease Biogeosciences. 2013 Mar 01; 10(3):3977-4023. . View in PubMed

Childhood air pollutant exposure and carotid artery intima-media thickness in young adults Circulation. 2012 Sep 25; 126(13):1614-20. . View in PubMed

Modeling the residential infiltration of outdoor PM(25) in the Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air). Environ Health Perspect. 2012 Jun; 120(6):824-30. . View in PubMed

Predictors of intra-community variation in air quality J Expo Sci Environ Epidemiol. 2012 Mar-Apr; 22(2):135-47. . View in PubMed

Parental stress increases the detrimental effect of traffic exposure on children's lung function Am J Respir Crit Care Med. 2011 Oct 01; 184(7):822-7. . View in PubMed

Residential traffic-related pollution exposures and exhaled nitric oxide in the children's health study Environ Health Perspect. 2011 Oct; 119(10):1472-7. . View in PubMed

Carotid artery intima-media thickness in college students: race/ethnicity matters Atherosclerosis. 2011 Aug; 217(2):441-6. . View in PubMed

Exhaled nitric oxide, susceptibility and new-onset asthma in the Children's Health Study Eur Respir J. 2011 Mar; 37(3):523-31. . View in PubMed

Childhood incident asthma and traffic-related air pollution at home and school Environ Health Perspect. 2010 Jul; 118(7):1021-6. . View in PubMed

Relationships of online exhaled, offline exhaled, and ambient nitric oxide in an epidemiologic survey of schoolchildren J Expo Sci Environ Epidemiol. 2009 Nov; 19(7):674-81. . View in PubMed

Global goods movement and the local burden of childhood asthma in southern California Am J Public Health. 2009 Nov; 99 Suppl 3:S622-8. . View in PubMed

Approach to estimating participant pollutant exposures in the Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air) Environ Sci Technol. 2009 Jul 01; 43(13):4687-93. . View in PubMed

In utero smoke exposure, glutathione S-transferase P1 haplotypes, and respiratory illness-related absence among schoolchildren Pediatrics. 2009 May; 123(5):1344-51. . View in PubMed

Respiratory symptoms following wildfire smoke exposure: airway size as a susceptibility factor Epidemiology. 2009 May; 20(3):451-9. . View in PubMed

Exhaled nitric oxide in a population-based study of southern California schoolchildren Respir Res. 2009 Apr 21; 10:28. . View in PubMed

Glutathione-S-transferase (GST) P1, GSTM1, exercise, ozone and asthma incidence in school children Thorax. 2009 Mar; 64(3):197-202. . View in PubMed

Glutathione S-transferase P1, maternal smoking, and asthma in children: a haplotype-based analysis Environ Health Perspect. 2008 Mar; 116(3):409-15. . View in PubMed

Ozone, oxidant defense genes, and risk of asthma during adolescence Am J Respir Crit Care Med. 2008 Feb 15; 177(4):388-95. . View in PubMed

Microsomal epoxide hydrolase, glutathione S-transferase P1, traffic and childhood asthma Thorax. 2007 Dec; 62(12):1050-7. . View in PubMed

Relationship between air pollution, lung function and asthma in adolescents Thorax. 2007 Nov; 62(11):957-63. . View in PubMed

Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort study Lancet. 2007 Feb 17; 369(9561):571-7. . View in PubMed

Dog ownership enhances symptomatic responses to air pollution in children with asthma Environ Health Perspect. 2006 Dec; 114(12):1910-5. . View in PubMed

Health effects of the 2003 Southern California wildfires on children Am J Respir Crit Care Med. 2006 Dec 01; 174(11):1221-8. . View in PubMed

Regular smoking and asthma incidence in adolescents Am J Respir Crit Care Med. 2006 Nov 15; 174(10):1094-100. . View in PubMed

Predicting residential ozone deficits from nearby traffic Sci Total Environ. 2006 Jun 15; 363(1-3):166-74. . View in PubMed

Associations of tumor necrosis factor G-308A with childhood asthma and wheezing Am J Respir Crit Care Med. 2006 May 01; 173(9):970-6. . View in PubMed

Mode of delivery is associated with asthma and allergy occurrences in children Ann Epidemiol. 2006 May; 16(5):341-6. . View in PubMed

Childhood asthma and exposure to traffic and nitrogen dioxide Epidemiology. 2005 Nov; 16(6):737-43. . View in PubMed

Air pollution exposure assessment for epidemiologic studies of pregnant women and children: lessons learned from the Centers for Children's Environmental Health and Disease Prevention Research Environ Health Perspect. 2005 Oct; 113(10):1447-54. . View in PubMed

Intercellular adhesion molecule-1 and childhood asthma Hum Genet. 2005 Sep; 117(5):476-84. . View in PubMed

Respiratory symptoms in relation to residential coal burning and environmental tobacco smoke among early adolescents in Wuhan, China: a cross-sectional study Environ Health. 2004 Dec 07; 3(1):14. . View in PubMed

Effects of ambient air pollutants on asthma medication use and wheezing among fourth-grade school children from 12 Southern California communities enrolled in The Children's Health Study Arch Environ Health. 2004 Oct; 59(10):505-14. . View in PubMed

Indoor allergens, asthma, and asthma-related symptoms among adolescents in Wuhan, China Ann Epidemiol. 2004 Sep; 14(8):543-50. . View in PubMed

Ambient endotoxin concentrations in PM10 from Southern California Environ Health Perspect. 2004 Apr; 112(5):583-8. . View in PubMed

Prospective study of air pollution and bronchitic symptoms in children with asthma Am J Respir Crit Care Med. 2003 Oct 01; 168(7):790-7. . View in PubMed

Breathless in Los Angeles: the exhausting search for clean air Am J Public Health. 2003 Sep; 93(9):1494-9. . View in PubMed

Obesity and the risk of newly diagnosed asthma in school-age children Am J Epidemiol. 2003 Sep 01; 158(5):406-15. . View in PubMed

Environmental tobacco smoke and absenteeism related to respiratory illness in schoolchildren Am J Epidemiol. 2003 May 15; 157(10):861-9. . View in PubMed

Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children Am J Respir Crit Care Med. 2002 Aug 15; 166(4):457-63. . View in PubMed

Association between air pollution and lung function growth in southern California children: results from a second cohort Am J Respir Crit Care Med. 2002 Jul 01; 166(1):76-84. . View in PubMed

Indoor risk factors for asthma in a prospective study of adolescents Epidemiology. 2002 May; 13(3):288-95. . View in PubMed

Asthma in exercising children exposed to ozone: a cohort study Lancet. 2002 Feb 02; 359(9304):386-91. . View in PubMed

Respiratory effects of relocating to areas of differing air pollution levels Am J Respir Crit Care Med. 2001 Dec 01; 164(11):2067-72. . View in PubMed

Family history and the risk of early-onset persistent, early-onset transient, and late-onset asthma Epidemiology. 2001 Sep; 12(5):577-83. . View in PubMed

Sex-specific effects of asthma on pulmonary function in children Am J Respir Crit Care Med. 2000 Nov; 162(5):1723-30. . View in PubMed

Association between air pollution and lung function growth in southern California children Am J Respir Crit Care Med. 2000 Oct; 162(4 Pt 1):1383-90. . View in PubMed

Quality of spirometry test performance in children and adolescents : experience in a large field study Chest. 2000 Sep; 118(3):665-71. . View in PubMed

Maternal smoking during pregnancy, environmental tobacco smoke exposure and childhood lung function Thorax. 2000 Apr; 55(4):271-6. . View in PubMed

Effect of spirometer temperature on FEV1 in a longitudinal epidemiological study Occup Environ Med. 1999 Oct; 56(10):718-20. . View in PubMed

Air pollution and bronchitic symptoms in Southern California children with asthma Environ Health Perspect. 1999 Sep; 107(9):757-60. . View in PubMed

A study of twelve Southern California communities with differing levels and types of air pollutionII. Effects on pulmonary function. Am J Respir Crit Care Med. 1999 Mar; 159(3):768-75. . View in PubMed

Initial field evaluation of the Harvard active ozone sampler for personal ozone monitoring J Expo Anal Environ Epidemiol. 1999 Mar-Apr; 9(2):143-9. . View in PubMed

A study of twelve Southern California communities with differing levels and types of air pollutionI. Prevalence of respiratory morbidity. Am J Respir Crit Care Med. 1999 Mar; 159(3):760-7. . View in PubMed

Acute effects of ambient ozone on asthmatic, wheezy, and healthy children Res Rep Health Eff Inst. 1998 May; (82):iii, 1-18; discussion 19-30. . View in PubMed

Chamber exposures of children to mixed ozone, sulfur dioxide, and sulfuric acid Arch Environ Health. 1997 May-Jun; 52(3):179-87. . View in PubMed

Short-term air pollution exposures and responses in Los Angeles area schoolchildren J Expo Anal Environ Epidemiol. 1996 Oct-Dec; 6(4):449-72. . View in PubMed

Effects of prolonged, repeated exposure to ozone, sulfuric acid, and their combination in healthy and asthmatic volunteers Am J Respir Crit Care Med. 1994 Aug; 150(2):431-40. . View in PubMed

Active and passive ozone samplers based on a reaction with a binary reagent Res Rep Health Eff Inst. 1994 Feb; (63):1-18; discussion 67-82. . View in PubMed

Determinants of the Spatial Distributions of Elemental Carbon and Particulate Matter in Eight Southern Californian Communities Atmos Environ (1994). 2014 Apr 01; 86:84-92. . View in PubMed

Comparing universal kriging and land-use regression for predicting concentrations of gaseous oxides of nitrogen (NOx) for the Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air) Atmos Environ (1994). 2011 Aug 01; 45(26):4412-4420. . View in PubMed

Exposures of older adults with chronic respiratory illness to nitrogen dioxideA combined laboratory and field study. Am Rev Respir Dis. 1992 Dec; 146(6):1480-6. . View in PubMed

Controlled exposures of volunteers to respirable carbon and sulfuric acid aerosols J Air Waste Manage Assoc. 1992 Jun; 42(6):770-6. . View in PubMed

Respiratory responses of young asthmatic volunteers in controlled exposures to sulfuric acid aerosol Am Rev Respir Dis. 1990 Aug; 142(2):343-8. . View in PubMed

Effect of exposures to ambient ozone on ventilatory lung function in children Am Rev Respir Dis. 1990 May; 141(5 Pt 1):1136-46. . View in PubMed

Responses to sulfur dioxide and exercise by medication-dependent asthmatics: effect of varying medication levels Arch Environ Health. 1990 Jan-Feb; 45(1):24-30. . View in PubMed

Experimental exposures of young asthmatic volunteers to 03 ppm nitrogen dioxide and to ambient air pollution. Toxicol Ind Health. 1989 Dec; 5(6):1025-34. . View in PubMed

Effect of droplet size on respiratory responses to inhaled sulfuric acid in normal and asthmatic volunteers Am Rev Respir Dis. 1989 Jul; 140(1):161-6. . View in PubMed

Acid fog: effects on respiratory function and symptoms in healthy and asthmatic volunteers Environ Health Perspect. 1989 Feb; 79:159-62. . View in PubMed

Repeated laboratory ozone exposures of volunteer Los Angeles residents: an apparent seasonal variation in response Toxicol Ind Health. 1988 Dec; 4(4):505-20. . View in PubMed

Effect of metaproterenol sulfate on mild asthmatics' response to sulfur dioxide exposure and exercise Arch Environ Health. 1988 Nov-Dec; 43(6):399-406. . View in PubMed

Respiratory dose-response study of normal and asthmatic volunteers exposed to sulfuric acid aerosol in the sub-micrometer size range Toxicol Ind Health. 1988 Jun; 4(2):173-84. . View in PubMed

Laboratory study of asthmatic volunteers exposed to nitrogen dioxide and to ambient air pollution Am Ind Hyg Assoc J. 1988 Apr; 49(4):143-9. . View in PubMed

Replicated dose-response study of sulfur dioxide effects in normal, atopic, and asthmatic volunteers Am Rev Respir Dis. 1987 Nov; 136(5):1127-34. . View in PubMed

Respiratory responses of exercising asthmatic volunteers exposed to sulfuric acid aerosol J Air Pollut Control Assoc. 1986 Dec; 36(12):1323-8. . View in PubMed

Dose-response study of asthmatic volunteers exposed to nitrogen dioxide during intermittent exercise Arch Environ Health. 1986 Sep-Oct; 41(5):292-6. . View in PubMed

A dose-response study of healthy, heavily exercising men exposed to ozone at concentrations near the ambient air quality standard Toxicol Ind Health. 1986 Jul; 2(1):99-112. . View in PubMed

Potential risks to human respiratory health from "acid fog": evidence from experimental studies of volunteers Environ Health Perspect. 1985 Nov; 63:57-61. . View in PubMed

Controlled exposure of volunteers with chronic obstructive pulmonary disease to nitrogen dioxide Arch Environ Health. 1985 Nov-Dec; 40(6):313-7. . View in PubMed

Respiratory effects of photochemical oxidant air pollution in exercising adolescents Am Rev Respir Dis. 1985 Sep; 132(3):619-22. . View in PubMed

Effects of exposure to 4 ppm nitrogen dioxide in healthy and asthmatic volunteers Arch Environ Health. 1985 Jul-Aug; 40(4):234-9. . View in PubMed

Effects of heat and humidity on the responses of exercising asthmatics to sulfur dioxide exposure Am Rev Respir Dis. 1985 Feb; 131(2):221-5. . View in PubMed

Comparative respiratory effects of ozone and ambient oxidant pollution exposure during heavy exercise J Air Pollut Control Assoc. 1984 Aug; 34(8):804-9. . View in PubMed

Asthmatics' responses to 6-hr sulfur dioxide exposures on two successive days Arch Environ Health. 1984 Jul-Aug; 39(4):313-9. . View in PubMed

Acute respiratory effects of Los Angeles smog in continuously exercising adults J Air Pollut Control Assoc. 1983 Nov; 33(11):1055-60. . View in PubMed

Laboratory evaluation of a disposable half-face mask for protection against ozone Am Rev Respir Dis. 1982 Nov; 126(5):818-21. . View in PubMed

Controlled exposures of human volunteers to sulfate aerosolsHealth effects and aerosol characterization. Am Rev Respir Dis. 1979 Aug; 120(2):319-27. . View in PubMed

A movable laboratory for controlled clinical studies of air pollution exposure J Air Pollut Control Assoc. 1979 Jul; 29(7):743-5. . View in PubMed

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