Keck School Faculty

Elaine Kaptein, MD
Elaine Kaptein, MD
Professor of Medicine (Part-Time)
Medicine
IRD 808 2020 Zonal Ave. Off Campus Los Angeles
A native of Saskatchewan, Canada, Dr. Kaptein began teaching at the Keck School of Medicine in the Endocrinology Division in 1977. She became a tenured Professor of Medicine in 1990, a position she currently holds. Dr. Kaptein is a distinguished member of the Western Society for Clinical Investigation, American Society of Nephrology, the Endocrine Society and the American Thyroid Association. An accomplished researcher and lecturer, Dr. Kaptein has been invited to speak on the topics of Endocrinology and Nephrology in such cities as Montreal, Milan, Tel Aviv, Jerusalem, Vienna and Rotterdam, to name a few.

Renal Organ System, Course Director: Teaching Award, Outstanding Year II Course, 2000

NIH: Grant R01 DK31431, 1984-1990

American College of Physicians: Fellow, 1981

NIH: General Clinical Research Center Physician Grant, 1980-1982

Royal College of Physicians of Canada : Fellow, 1978

University of Saskatchewan : Student Research Scholarship, 1969-1971

Relationship of inferior vena cava collapsibility to ultrafiltration volume achieved in critically ill hemodialysis patients Int J Nephrol Renovasc Dis. 2018; 11:195-209. . View in PubMed

Focused Real-Time Ultrasonography for Nephrologists Int J Nephrol. 2017; 2017:3756857. . View in PubMed

A systematic literature search and review of sodium concentrations of body fluids? . Clin Nephrol. 2016 10; 86(10):203-28.. View in PubMed

Is an isolated TSH elevation in chronic nonthyroidal illness "subclinical hypothyroidism"? J Clin Endocrinol Metab. 2014 Nov; 99(11):4015-26.. View in PubMed

Serum 25-hydroxyvitamin D deficiency; a risk factor for chronic kidney disease in ambulatory indigent patients Endocr Pract. 2014 Mar; 20(3):236-43. . View in PubMed

Vitamin D deficiency in urban indigent patients in Southern California Endocr Pract. 2013 May-Jun; 19(3):404-13. . View in PubMed

Thyroid hormones and their placental deiodination in normal and pre-eclamptic pregnancy Placenta. 2013 May; 34(5):395-400. . View in PubMed

Assessment of maximum weight change and duration of therapeutic effect for non-surgical treatment of obesity using an exponential model Eat Weight Disord. 2012 Dec; 17(4):e234-43. . View in PubMed

Low pleural fluid-to-serum glucose gradient indicates pleuroperitoneal communication in peritoneal dialysis patients: presentation of two cases and a review of the literature Nephrol Dial Transplant. 2012 Mar; 27(3):1212-9. . View in PubMed

Clinical review: Thyroid hormone therapy for postoperative nonthyroidal illnesses: a systematic review and synthesis J Clin Endocrinol Metab. 2010 Oct; 95(10):4526-34. . View in PubMed

Thyroid hormone therapy for obesity and nonthyroidal illnesses: a systematic review J Clin Endocrinol Metab. 2009 Oct; 94(10):3663-75. . View in PubMed

Comments regarding "Subclinical hyperthyroidism in cats: a spontaneous model of subclinical toxic nodular goiter in humans? ". Thyroid. 2008 Dec; 18(12):1339-40; author reply 1341.. View in PubMed

Induction of type 3 deiodinase activity in inflammatory cells of mice with chronic local inflammation Endocrinology. 2005 Dec; 146(12):5128-34. . View in PubMed

Assessing thyroid hormone status in a patient with thyroid disease and renal failure: from theory to practice Thyroid. 2004 May; 14(5):397-400. . View in PubMed

Dronerarone acts as a selective inhibitor of 3,5,3'-triiodothyronine binding to thyroid hormone receptor-alpha1: in vitro and in vivo evidence Endocrinology. 2003 Feb; 144(2):552-8. . View in PubMed

Sulfation of thyroid hormone and dopamine during human development: ontogeny of phenol sulfotransferases and arylsulfatase in liver, lung, and brain J Clin Endocrinol Metab. 2001 Jun; 86(6):2734-42. . View in PubMed

Radioiodine dosimetry in patients with end-stage renal disease receiving continuous ambulatory peritoneal dialysis therapy J Clin Endocrinol Metab. 2000 Sep; 85(9):3058-64. . View in PubMed

Characterization of the uridine diphosphate-glucuronosyltransferase-catalyzing thyroid hormone glucuronidation in man J Clin Endocrinol Metab. 2000 Aug; 85(8):2879-83. . View in PubMed

Cloning and characterization of type III iodothyronine deiodinase from the fish Oreochromis niloticus Endocrinology. 1999 Aug; 140(8):3666-73. . View in PubMed

Characterization of human iodothyronine sulfotransferases J Clin Endocrinol Metab. 1999 Apr; 84(4):1357-64. . View in PubMed

Diagnostic sonography of HIV-associated nephropathy: new observations and clinical correlation AJR Am J Roentgenol. 1998 Sep; 171(3):713-6. . View in PubMed

Ontogeny of iodothyronine deiodinases in human liver J Clin Endocrinol Metab. 1998 Aug; 83(8):2868-74. . View in PubMed

Characterization of a propylthiouracil-insensitive type I iodothyronine deiodinase Endocrinology. 1997 Dec; 138(12):5153-60. . View in PubMed

Characterization of iodothyronine sulfotransferase activity in rat liver Endocrinology. 1997 Dec; 138(12):5136-43. . View in PubMed

Expression of chicken hepatic type I and type III iodothyronine deiodinases during embryonic development Endocrinology. 1997 Dec; 138(12):5144-52. . View in PubMed

Effects of 5,5'-diphenylhydantoin on the metabolic pathway of thyroid hormone in rats Eur J Endocrinol. 1997 Mar; 136(3):324-9. . View in PubMed

Hormone-specific alterations of T4, T3, and reverse T3 metabolism with recent ethanol abstinence in humans Am J Physiol. 1997 Feb; 272(2 Pt 1):E191-200. . View in PubMed

Structure-activity relationships for thyroid hormone deiodination by mammalian type I iodothyronine deiodinases Endocrinology. 1997 Jan; 138(1):213-9. . View in PubMed

Gender-specific changes in thyroid hormone-glucuronidating enzymes in rat liver during short-term fasting and long-term food restriction Eur J Endocrinol. 1996 Oct; 135(4):489-97. . View in PubMed

Effects of long-term food reduction on the hypothalamus-pituitary-thyroid axis in male and female rats J Endocrinol. 1996 Aug; 150(2):169-78. . View in PubMed

Thyroid hormone metabolism and thyroid diseases in chronic renal failure Endocr Rev. 1996 Feb; 17(1):45-63. . View in PubMed

Effects of 5, 5'-diphenylhydantoin on the thyroid status in rats Eur J Endocrinol. 1996 Feb; 134(2):221-4. . View in PubMed

Different effects of continuous infusion of interleukin-1 and interleukin-6 on the hypothalamic-hypophysial-thyroid axis Endocrinology. 1994 Oct; 135(4):1336-45. . View in PubMed

Rapid glucuronidation of tri- and tetraiodothyroacetic acid to ester glucuronides in human liver and to ether glucuronides in rat liver Endocrinology. 1994 Sep; 135(3):1004-9. . View in PubMed

Thyroid hormone metabolismA comparative evaluation. Vet Clin North Am Small Anim Pract. 1994 May; 24(3):431-66. . View in PubMed

Thyroid function and deiodinase activities in rats with marginal iodine deficiency Biol Trace Elem Res. 1994 Mar; 40(3):237-46. . View in PubMed

Glucuronidation of thyroid hormone in rat liver: effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions Endocrinology. 1993 Nov; 133(5):2177-86. . View in PubMed

Clinical application of free thyroxine determinations Clin Lab Med. 1993 Sep; 13(3):653-72. . View in PubMed

Glucuronidation of thyroid hormone by human bilirubin and phenol UDP-glucuronyltransferase isoenzymes FEBS Lett. 1993 Jun 21; 324(3):358-60. . View in PubMed

Increased glucuronidation of thyroid hormone in hexachlorobenzene-treated rats Biochem Pharmacol. 1993 Feb 09; 45(3):627-31. . View in PubMed

Hyponatremia in hospitalized patients with the acquired immunodeficiency syndrome (AIDS) and the AIDS-related complex Am J Med. 1993 Feb; 94(2):169-74. . View in PubMed

Multiple UDP-glucuronyltransferases for the glucuronidation of thyroid hormone with preference for 3,3',5'-triiodothyronine (reverse T3) FEBS Lett. 1993 Jan 02; 315(1):65-8. . View in PubMed

Myocardial texture and cardiac calcification in uremia Miner Electrolyte Metab. 1993; 19(1):21-4. . View in PubMed

Thyroxine and triiodothyronine distribution and metabolism in thyroxine-replaced athyreotic dogs and normal humans Am J Physiol. 1993 Jan; 264(1 Pt 1):E90-100. . View in PubMed

Effects of prednisone on thyroxine and 3,5,3'-triiodothyronine metabolism in normal dogs Endocrinology. 1992 Mar; 130(3):1669-79. . View in PubMed

Compression of the left brachiocephalic vein by the innominate artery resulting in massive arm edema in a hemodialysis patient Am J Nephrol. 1992; 12(1-2):108-10. . View in PubMed

Differential expression and ciprofibrate induction of hepatic UDP-glucuronyltransferases for thyroxine and triiodothyronine in Fischer rats Biochem Pharmacol. 1991 Jul 05; 42(2):444-6. . View in PubMed

rT3 metabolism in patients with nephrotic syndrome and normal GFR compared with normal subjects Am J Physiol. 1991 Apr; 260(4 Pt 1):E641-50. . View in PubMed

Comparison of reverse triiodothyronine distribution and metabolism in normal dogs and humans Endocrinology. 1990 Apr; 126(4):2003-14. . View in PubMed

Separation of iodothyronines from iodinated metabolites in serum from reverse T3 tracer kinetic studies in man and dog: a comparison of two methods Horm Metab Res. 1989 Dec; 21(12):678-81. . View in PubMed

Thyroid hormone levels in the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex West J Med. 1989 Dec; 151(6):627-31. . View in PubMed

Alterations in 3,3'5'-triiodothyronine metabolism in response to propylthiouracil, dexamethasone, and thyroxine administration in man J Clin Invest. 1989 Nov; 84(5):1650-6. . View in PubMed

Metabolism of triiodothyronine in rat hepatocytes Endocrinology. 1989 Oct; 125(4):2187-97. . View in PubMed

Serum triiodothyronine sulfate in man measured by radioimmunoassay J Clin Endocrinol Metab. 1989 Sep; 69(3):552-6. . View in PubMed

Increased plasma 3,5,3'-triiodothyronine sulfate in rats with inhibited type I iodothyronine deiodinase activity, as measured by radioimmunoassay Endocrinology. 1989 Feb; 124(2):740-5. . View in PubMed

Amiodarone alters thyroxine transfer and distribution in humans Metabolism. 1988 Dec; 37(12):1107-13. . View in PubMed

Deiodination of thyroid hormone by human liver J Clin Endocrinol Metab. 1988 Jul; 67(1):17-24. . View in PubMed

The thyroid in end-stage renal disease Medicine (Baltimore). 1988 May; 67(3):187-97. . View in PubMed

The relation of thyroid indices in the critically ill patient to prognosis and nutritional factors Surg Gynecol Obstet. 1988 Mar; 166(3):223-8. . View in PubMed

Renal biopsy-related hemorrhage: frequency and comparison of CT and sonography J Comput Assist Tomogr. 1987 Nov-Dec; 11(6):1031-4. . View in PubMed

Thyroxine transfer and distribution in critical nonthyroidal illnesses, chronic renal failure, and chronic ethanol abuse J Clin Endocrinol Metab. 1987 Oct; 65(4):606-16. . View in PubMed

Diagnosis of hypothyroidism in patients with end-stage renal disease Am J Nephrol. 1987; 7(3):192-7. . View in PubMed

Acute hemodynamic effects of levothyroxine loading in critically ill hypothyroid patients Arch Intern Med. 1986 Apr; 146(4):662-6. . View in PubMed

Thyroid function in renal failure Contrib Nephrol. 1986; 50:64-72. . View in PubMed

Acute renal failure due to bilateral ureteral obstruction by metastases from breast cancer Nephron. 1986; 42(1):23-8. . View in PubMed

Thyroxine kinetics in nonthyroidal illnesses J Endocrinol Invest. 1986; 9 Suppl 4:37-46. . View in PubMed

Metabolic and hormonal factors as predictors of nitrogen retention in obese men consuming very low calorie diets Metabolism. 1985 Feb; 34(2):101-5. . View in PubMed

Relationship between the changes in serum thyroid hormone levels and protein status during prolonged protein supplemented caloric deprivation Clin Endocrinol (Oxf). 1985 Jan; 22(1):1-15. . View in PubMed

Inactivation and affinity-labeling of rat liver iodothyronine deiodinase with N-bromoacetyl-3,3',5-triiodothyronine Biochem Biophys Res Commun. 1984 Oct 30; 124(2):475-83. . View in PubMed

Serum thyroid hormone indexes in patients with primary hyperparathyroidism Arch Intern Med. 1984 Feb; 144(2):313-5. . View in PubMed

Peripheral tissue mechanism for maintenance of serum triiodothyronine values in a thyroxine-deficient state in man J Clin Invest. 1984 Feb; 73(2):570-5. . View in PubMed

Severe hyperuricemia in patients with volume depletion Am J Nephrol. 1984; 4(2):77-80. . View in PubMed

Hemodynamic effects of thyroid hormone Contrib Nephrol. 1984; 41:151-9. . View in PubMed

Alterations of serum reverse triiodothyronine and thyroxine kinetics in chronic renal failure: role of nutritional status, chronic illness, uremia, and hemodialysis Kidney Int Suppl. 1983 Dec; 16:S180-6. . View in PubMed

Serum reverse triiodothyronine and thyroxine kinetics in patients with chronic renal failure J Clin Endocrinol Metab. 1983 Jul; 57(1):181-9. . View in PubMed

Dynamics of serum thyrotropin and thyroid hormone changes in fasting J Clin Endocrinol Metab. 1983 May; 56(5):883-8. . View in PubMed

Influence of nonthyroidal illnesses on serum thyroid hormone indices in hyperthyroidism West J Med. 1983 May; 138(5):670-5. . View in PubMed

Electron radiography in the evaluation of solitary nodules in the thyroid gland AJR Am J Roentgenol. 1983 Feb; 140(2):398-9. . View in PubMed

Quiz of the month: chronic renal failure and hypothyroidism Am J Nephrol. 1983 Jan-Feb; 3(1):43, 50. . View in PubMed

Quiz of the month: nephrotic syndrome and altered thyroid hormone levels Am J Nephrol. 1983 Jan-Feb; 3(1):43, 50. . View in PubMed

Urinary immunoprecipitation method for estimation of thyroxine to triiodothyronine conversion in altered thyroid states J Clin Endocrinol Metab. 1982 Oct; 55(4):666-70. . View in PubMed

Relationship of altered thyroid hormone indices to survival in nonthyroidal illnesses Clin Endocrinol (Oxf). 1982 Jun; 16(6):565-74. . View in PubMed

Peripheral serum thyroxine, triiodothyronine and reverse triiodothyronine kinetics in the low thyroxine state of acute nonthyroidal illnessesA noncompartmental analysis. J Clin Invest. 1982 Mar; 69(3):526-35. . View in PubMed

Pattern of recovery of thyroid hormone indices associated with treatment of diabetes mellitus J Clin Endocrinol Metab. 1982 Feb; 54(2):362-6. . View in PubMed

Thyroid function in patients with nephrotic syndrome and normal renal function Am J Nephrol. 1982; 2(2):70-6. . View in PubMed

Thyroid hormone metabolism in renal diseases Contrib Nephrol. 1982; 33:122-35. . View in PubMed

Thyroxine metabolism in the low thyroxine state of critical nonthyroidal illnesses J Clin Endocrinol Metab. 1981 Oct; 53(4):764-71. . View in PubMed

Free thyroxine estimates in nonthyroidal illness: comparison of eight methods J Clin Endocrinol Metab. 1981 Jun; 52(6):1073-7. . View in PubMed

Hepatic thyroxine (T4) uptake as a mechanism for regulation of triiodothyronine (T3) generation in rat liver slices Life Sci. 1981 Apr 13-20; 28(15-16):1713-8. . View in PubMed

Alterations of thyroid hormone indices in acute renal failure and in acute critical illness with and without acute renal failure Am J Nephrol. 1981; 1(3-4):138-43. . View in PubMed

Intestinal calcium absorption in patients with hyperthyroidism J Clin Endocrinol Metab. 1980 Nov; 51(5):995-7. . View in PubMed

Modulation by thyroid status of the glucagon receptor-adenyl cyclase system in rat liver plasma membranes Endocrinology. 1980 Sep; 107(3):684-90. . View in PubMed

Effects of prolonged dopamine infusion on anterior pituitary function in normal males J Clin Endocrinol Metab. 1980 Sep; 51(3):488-91. . View in PubMed

Prolonged dopamine administration and thyroid hormone economy in normal and critically ill subjects J Clin Endocrinol Metab. 1980 Aug; 51(2):387-93. . View in PubMed

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