Eric James Kezirian
Vice Chair of the Caruso Department of Otolaryngology-Head & Neck Surgery
American Academy of Sleep Medicine: Fellow, 2014
American Academy of Otolaryngology - Head and Neck Surgery: Distinguished Service Award, 2013
American Academy of Otolaryngology - Head and Neck Surgery: Honor Award, 2008
University of Pennsylvania School of Medicine: Joel Gordon Miller Award, 1997
University of Pennsylvania: Alpha Omega Alpha, 1996
: Charles A. Lauffer Foundation Scholarship, 1995
Harvard College: Magna cum laude, 1992
: Rotary Foundation Ambassadorial Scholarship, 1992
Harvard College: Harvard College Scholarship, 1989-1992
Comparison of Free Flap Outcomes at a University Hospital versus County Hospital Setting for Head and Neck Reconstruction Int Arch Otorhinolaryngol. 2023 Apr; 27(2):e183-e190. . View in PubMed
International Consensus Statement on Obstructive Sleep Apnea Int Forum Allergy Rhinol. 2022 Sep 06. . View in PubMed
Comparison of Traditional Upper Airway Surgery and Upper Airway Stimulation for Obstructive Sleep Apnea Ann Otol Rhinol Laryngol. 2021 Apr; 130(4):370-376. . View in PubMed
Upper Airway Classification in Sleep Endoscopy Examinations using Convolutional Recurrent Neural Networks Annu Int Conf IEEE Eng Med Biol Soc. 2021 11; 2021:3957-3960. . View in PubMed
Wavelet-based CNN for Predicting PAP Adherence Using Overnight Polysomnography Recordings: a Pilot Study Annu Int Conf IEEE Eng Med Biol Soc. 2021 11; 2021:616-620. . View in PubMed
Altered regional cerebral blood flow in obstructive sleep apnea is associated with sleep fragmentation and oxygen desaturation J Cereb Blood Flow Metab. 2021 10; 41(10):2712-2724. . View in PubMed
Drug-Induced Sleep Endoscopy and Hypoglossal Nerve Stimulation Outcomes: A Multicenter Cohort Study Laryngoscope. 2021 07; 131(7):1676-1682. . View in PubMed
Transoral Robotic Surgery (TORS) Versus Non-TORS Tongue Resection for Obstructive Sleep Apnea Laryngoscope. 2021 05; 131(5):E1735-E1740. . View in PubMed
High-quality research is needed much more than commonly published (low-quality) meta-analyses J Clin Sleep Med. 2021 09 01; 17(9):1961-1962. . View in PubMed
Methodological Quality of Systematic Reviews and Meta-analyses Published in High-Impact Otolaryngology Journals Otolaryngol Head Neck Surg. 2020 Nov; 163(5):892-905. . View in PubMed
Laryngoscope. 2020 12; 130(12):E950. . View in PubMed
Results of the ADHERE upper airway stimulation registry and predictors of therapy efficacy Laryngoscope. 2020 05; 130(5):1333-1338. . View in PubMed
Making Sense of the Noise: Toward Rational Treatment for Obstructive Sleep Apnea Am J Respir Crit Care Med. 2020 12 01; 202(11):1503-1508. . View in PubMed
Perioperative Care of Patients With Obstructive Sleep Apnea Undergoing Upper Airway Surgery: A Review and Consensus Recommendations JAMA Otolaryngol Head Neck Surg. 2019 Aug 01; 145(8):751-760. . View in PubMed
Association between REM sleep and obstructive sleep apnea in obese and overweight adolescents Sleep Breath. 2019 Jun; 23(2):645-650. . View in PubMed
Safety and efficacy of sphenopalatine ganglion stimulation for chronic cluster headache: a double-blind, randomised controlled trial Lancet Neurol. 2019 12; 18(12):1081-1090. . View in PubMed
Previous Surgery and Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea Otolaryngol Head Neck Surg. 2019 11; 161(5):897-903. . View in PubMed
Upper Airway Stimulation Response in Older Adults with Moderate to Severe Obstructive Sleep Apnea Otolaryngol Head Neck Surg. 2019 10; 161(4):714-719. . View in PubMed
Drug-Induced Sleep Endoscopy and Surgical Outcomes: A Multicenter Cohort Study Laryngoscope. 2019 03; 129(3):761-770. . View in PubMed
Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry Eur Respir J. 2019 01; 53(1). . View in PubMed
Drug-Induced Sleep Endoscopy Findings in Supine vs Nonsupine Body Positions in Positional and Nonpositional Obstructive Sleep Apnea JAMA Otolaryngol Head Neck Surg. 2019 02 01; 145(2):159-165. . View in PubMed
Obstructive Sleep Apnea in Cardiovascular Disease: A Review of the Literature and Proposed Multidisciplinary Clinical Management Strategy J Am Heart Assoc. 2019 01 08; 8(1):e010440. . View in PubMed
Upper Airway Stimulation for Obstructive Sleep Apnea: Results from the ADHERE Registry Otolaryngol Head Neck Surg. 2018 08; 159(2):379-385. . View in PubMed
Poor sleep quality and insufficient sleep of a collegiate student-athlete population Sleep Health. 2018 06; 4(3):251-257. . View in PubMed
Hyoepiglottic ligament collagen and elastin fiber composition and changes associated with aging Laryngoscope. 2018 05; 128(5):1245-1248. . View in PubMed
Suspension Palatoplasty for Obstructive Sleep Apnea- A Preliminary Study Sci Rep. 2018 03 09; 8(1):4224. . View in PubMed
Application of drug-induced sleep endoscopy in patients treated with upper airway stimulation therapy World J Otorhinolaryngol Head Neck Surg. 2017 Jun; 3(2):92-96. . View in PubMed
Airflow Shape Is Associated With the Pharyngeal Structure Causing OSA Chest. 2017 09; 152(3):537-546. . View in PubMed
Sleep-disordered breathing in pediatric head and neck vascular malformations Laryngoscope. 2017 09; 127(9):2159-2164. . View in PubMed
National Database Analysis of Single-Level versus Multilevel Sleep Surgery Otolaryngol Head Neck Surg. 2017 05; 156(5):955-961. . View in PubMed
Advances in the Diagnosis of Obstructive Sleep Apnea: Drug-Induced Sleep Endoscopy Adv Otorhinolaryngol. 2017; 80:22-27. . View in PubMed
Drug-Induced Sleep Endoscopy Otolaryngol Clin North Am. 2016 Dec; 49(6):1359-1372. . View in PubMed
Acclimation settings with identical or similar sensation and functional thresholds Laryngoscope. 2016 09; 126 Suppl 7:S20-1. . View in PubMed
Society of Anesthesia and Sleep Medicine Guidelines on Preoperative Screening and Assessment of Adult Patients With Obstructive Sleep Apnea Anesth Analg. 2016 08; 123(2):452-73. . View in PubMed
Efficacy of Coblation Endoscopic Lingual Lightening in Multilevel Surgery for Obstructive Sleep Apnea JAMA Otolaryngol Head Neck Surg. 2016 05 01; 142(5):438-43. . View in PubMed
Coblation endoscopic lingual lightening (CELL) for obstructive sleep apnea Eur Arch Otorhinolaryngol. 2016 Jan; 273(1):231-6. . View in PubMed
A Pediatric Grading Scale for Lingual Tonsil Hypertrophy Otolaryngol Head Neck Surg. 2016 Jan; 154(1):171-4. . View in PubMed
Long-Term Cost-Effectiveness of Upper Airway Stimulation for the Treatment of Obstructive Sleep Apnea: A Model-Based Projection Based on the STAR Trial Sleep. 2015 May 01; 38(5):735-44. . View in PubMed
Does my tongue look fat? Sleep. 2014 Oct 01; 37(10):1583-4.. View in PubMed
Surgical Evaluation in Obstructive Sleep Apnea: Climbing the Steep Part of the Learning Curve JAMA Otolaryngol Head Neck Surg. 2014 Jun; 140(6):568. . View in PubMed
Management of obstructive sleep apnea in adults Ann Intern Med. 2014 Mar 04; 160(5):367. . View in PubMed
Hypoglossal nerve stimulation improves obstructive sleep apnea: 12-month outcomes J Sleep Res. 2014 Feb; 23(1):77-83. . View in PubMed
Oral tongue squamous cell carcinoma in young women: a matched comparison-do outcomes justify treatment intensity? ISRN Otolaryngol. 2014; 2014:529395.. View in PubMed
Pleomorphic adenoma of the major salivary glands: diagnostic utility of FNAB and MRI Laryngoscope. 2013 Dec; 123(12):3056-60. . View in PubMed
SKUP3: a major step forward in sleep surgery research Thorax. 2013 Sep; 68(9):801-2. . View in PubMed
Oral tongue squamous cell carcinoma in never-smokers: analysis of clinicopathologic characteristics and survival Otolaryngol Head Neck Surg. 2013 Jul; 149(1):89-96. . View in PubMed
Observer variation in drug-induced sleep endoscopy: experienced versus nonexperienced ear, nose, and throat surgeons Sleep. 2013 Jun 01; 36(6):947-53. . View in PubMed
What are the health risks of untreated snoring without obstructive sleep apnea? Laryngoscope. 2013 Jun; 123(6):1321-2.. View in PubMed
Snoring without OSA and health consequences: the jury is still out Sleep. 2013 Apr 01; 36(4):613. . View in PubMed
Obstructive sleep apnea during rapid eye movement sleep, daytime sleepiness, and quality of life in older men in Osteoporotic Fractures in Men (MrOS) Sleep Study J Clin Sleep Med. 2013 Mar 15; 9(3):191-8. . View in PubMed
Heterotopic ossification and delayed foreign body reaction after hyoid suspension for obstructive sleep apnea Otolaryngol Head Neck Surg. 2013 Mar; 148(3):527-8. . View in PubMed
Hypopharyngeal surgery in obstructive sleep apnea: practice patterns, perceptions, and attitudes Otolaryngol Head Neck Surg. 2012 Nov; 147(5):964-71. . View in PubMed
Comparison of drug-induced sleep endoscopy and lateral cephalometry in obstructive sleep apnea Laryngoscope. 2012 Nov; 122(11):2600-5. . View in PubMed
Drug-induced sleep endoscopy in persistent pediatric sleep-disordered breathing after adenotonsillectomy Arch Otolaryngol Head Neck Surg. 2012 Jul; 138(7):638-43. . View in PubMed
Hypoglossal nerve stimulation and airway changes under fluoroscopy Otolaryngol Head Neck Surg. 2012 Jun; 146(6):1017-22. . View in PubMed
Reliability and validity of the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale in older men J Gerontol A Biol Sci Med Sci. 2012 Apr; 67(4):433-9. . View in PubMed
Hyoid bone advancement for improving airway patency: cadaver study of a magnet-based system Otolaryngol Head Neck Surg. 2012 Mar; 146(3):491-6. . View in PubMed
Acute upper airway responses to hypoglossal nerve stimulation during sleep in obstructive sleep apnea Am J Respir Crit Care Med. 2012 Feb 15; 185(4):420-6. . View in PubMed
Validation of the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale in older black and white women Sleep Med. 2012 Jan; 13(1):36-42. . View in PubMed
Treatment of trigger-point hypersensitivity of gag reflex following surgical treatment of obstructive sleep apnea Otolaryngol Head Neck Surg. 2011 Dec; 145(6):1055-6. . View in PubMed
Treating obstructive sleep apnea with hypoglossal nerve stimulation Sleep. 2011 Nov 01; 34(11):1479-86. . View in PubMed
Drug-induced sleep endoscopy: the VOTE classification Eur Arch Otorhinolaryngol. 2011 Aug; 268(8):1233-1236. . View in PubMed
The effects of sleep extension on the athletic performance of collegiate basketball players Sleep. 2011 Jul 01; 34(7):943-50. . View in PubMed
Neck dissections in the United States from 2000 to 2006: volume, indications, and regionalization Head Neck. 2011 Jun; 33(6):768-73. . View in PubMed
Nonresponders to pharyngeal surgery for obstructive sleep apnea: insights from drug-induced sleep endoscopy Laryngoscope. 2011 Jun; 121(6):1320-6. . View in PubMed
Reporting results of obstructive sleep apnea syndrome surgery trials Otolaryngol Head Neck Surg. 2011 Apr; 144(4):496-9. . View in PubMed
Electrical stimulation of the hypoglossal nerve in the treatment of obstructive sleep apnea Sleep Med Rev. 2010 Oct; 14(5):299-305. . View in PubMed
Obstructive sleep apnea surgery practice patterns in the United States: 2000 to 2006 Otolaryngol Head Neck Surg. 2010 Sep; 143(3):441-7. . View in PubMed
Changes in obstructive sleep apnea severity, biomarkers, and quality of life after multilevel surgery Laryngoscope. 2010 Jul; 120(7):1481-8. . View in PubMed
Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions Respirology. 2010 May; 15(4):587-95. . View in PubMed
Interrater reliability of drug-induced sleep endoscopy Arch Otolaryngol Head Neck Surg. 2010 Apr; 136(4):393-7. . View in PubMed
Is there a vicious cycle between obstructive sleep apnea and laryngopharyngeal reflux disease? Med Hypotheses. 2009 Nov; 73(5):706-8.. View in PubMed
Test-retest reliability of drug-induced sleep endoscopy Otolaryngol Head Neck Surg. 2009 May; 140(5):646-51. . View in PubMed
Behavioral correlates of sleep-disordered breathing in older men Sleep. 2009 Feb; 32(2):253-61. . View in PubMed
Resting energy expenditure in adults with sleep disordered breathing Arch Otolaryngol Head Neck Surg. 2008 Dec; 134(12):1270-5. . View in PubMed
Behavioral correlates of sleep-disordered breathing in older women Sleep. 2007 Sep; 30(9):1181-8. . View in PubMed
Risk factors for serious complication after uvulopalatopharyngoplasty Arch Otolaryngol Head Neck Surg. 2006 Oct; 132(10):1091-8. . View in PubMed
Efficacy of small reconstruction plates in vascularized bone graft mandibular reconstruction Head Neck. 2006 Jul; 28(7):573-9. . View in PubMed
Hypopharyngeal surgery in obstructive sleep apnea: an evidence-based medicine review Arch Otolaryngol Head Neck Surg. 2006 Feb; 132(2):206-13. . View in PubMed
Incidence of complications in radiofrequency treatment of the upper airway Laryngoscope. 2005 Jul; 115(7):1298-304. . View in PubMed
Outcomes of hyoid suspension for the treatment of obstructive sleep apnea Arch Otolaryngol Head Neck Surg. 2005 May; 131(5):440-5. . View in PubMed
The impact of extended sleep on daytime alertness, vigilance, and mood Sleep Med. 2004 Sep; 5(5):441-8. . View in PubMed
Incidence of serious complications after uvulopalatopharyngoplasty Laryngoscope. 2004 Mar; 114(3):450-3. . View in PubMed
Introduction to cost analysis in facial plastic surgery Facial Plast Surg. 2002 May; 18(2):95-9. . View in PubMed
Accuracy of terminology and methodology in economic analyses in otolaryngology Otolaryngol Head Neck Surg. 2001 May; 124(5):496-502. . View in PubMed
Effects of compensation method on physician behaviors Am J Manag Care. 2001 Apr; 7(4):363-73. . View in PubMed
Cost and cost-effectiveness of universal screening for hearing loss in newborns Otolaryngol Head Neck Surg. 2001 Apr; 124(4):359-67. . View in PubMed
Imaging quiz case 3Cervical tuberculous lymphadenopathy (scrofula). Arch Otolaryngol Head Neck Surg. 2000 Dec; 126(12):15011504-5. . View in PubMed
Dr. Kezirian utilizes a wide array of procedures and the latest research, including his own, to provide his patients with the most appropriate, effective treatment plan. His research has addressed the most important questions in the field, including how surgeons should choose procedures, how well surgery works, and the development of new surgical techniques and novel therapies. This work has been supported by the National Institutes of Health and other organizations. Dr. Kezirian has led a number of major clinical trials, and he has many active research studies. He gives lectures frequently across the country and the world.
After graduating magna cum laude from Harvard College, he obtained a Master of Science degree from the University of Oxford and then received his medical degree from the University of Pennsylvania. During his residency training in otolaryngology-head and neck surgery at the University of Washington, Dr. Kezirian received a Master of Public Health degree. Following his fellowship in sleep surgery at Stanford University, he joined the faculty at the University of California, San Francisco. There Dr. Kezirian was the director of the Division of Sleep Surgery in the Department of Otolaryngology—Head and Neck Surgery prior to coming to USC.
Dr. Kezirian is Board-certified both in otolaryngology-head & neck surgery and sleep medicine.
More information about Dr. Kezirian's research and clinical work can be found on his website: www.sleep-doctor.com.
https://keck.usc.edu/otolaryngology/
