Keck School Faculty

Gere S Dizerega, MD
Gere S Dizerega, MD
Professor of Research Obstetrics & Gynecology
Obstetrics & Gynecology
LRB 1321 N. Mission Road Off Campus Los Angeles
Dr. diZerega continues to perform research in the area of etiology of pelvic adhesions and prevention of pelvic adhesions following surgical procedures in the female pelvis. In 2000-2001 Dr. diZerega performed research to determine the efficacy of a new agent to prevent adhesions after surgical procedures in the female pelvis. Efficacy and safety of 4% 120 dextran solution was studies in 20 subjects.

Pharmacokinetic Profile of Inhaled Submicron Particle Paclitaxel (NanoPac®) in a Rodent Model J Aerosol Med Pulm Drug Deliv. 2018 Oct 25. . View in PubMed

Development of a guinea pig cutaneous radiation injury model using low penetrating X-rays Int J Radiat Biol. 2016 08; 92(8):434-43. . View in PubMed

Effect of combined radiation injury on cell death and inflammation in skin Apoptosis. 2015 Jul; 20(7):892-906. . View in PubMed

NorLeu3-Angiotensin (1-7) [DSC127] as a Therapy for the Healing of Diabetic Foot Ulcers Adv Wound Care (New Rochelle). 2015 Jun 01; 4(6):339-345. . View in PubMed

A phase I study of intraperitoneal nanoparticulate paclitaxel (Nanotax®) in patients with peritoneal malignancies Cancer Chemother Pharmacol. 2015 May; 75(5):1075-87. . View in PubMed

Angiotensin 1 - 7 stimulation of platelet recovery Expert Opin Investig Drugs. 2014 Apr; 23(4):551-9. . View in PubMed

Angiotensin-(1-7) synergizes with colony-stimulating factors in hematopoietic recovery Cancer Chemother Pharmacol. 2013 Dec; 72(6):1235-45. . View in PubMed

Contribution of the Local RAS to Hematopoietic Function: A Novel Therapeutic Target Front Endocrinol (Lausanne). 2013 Oct 23; 4:157. . View in PubMed

Pharmacodynamic stimulation of thrombogenesis by angiotensin (1-7) in recurrent ovarian cancer patients receiving gemcitabine and platinum-based chemotherapy Cancer Chemother Pharmacol. 2013 Apr; 71(4):965-72. . View in PubMed

Effects of combined radiation and burn injury on the renin-angiotensin system Wound Repair Regen. 2013 Jan-Feb; 21(1):131-40. . View in PubMed

NorLeu3-A(1-7) stimulation of diabetic foot ulcer healing: results of a randomized, parallel-group, double-blind, placebo-controlled phase 2 clinical trial Wound Repair Regen. 2012 Jul-Aug; 20(4):482-90. . View in PubMed

Accelerated hematopoietic recovery with angiotensin-(1-7) after total body radiation Int J Radiat Biol. 2012 Jun; 88(6):466-76. . View in PubMed

Angiotensin-(1-7) administration reduces oxidative stress in diabetic bone marrow Endocrinology. 2012 May; 153(5):2189-97. . View in PubMed

Basal levels of CD34 positive cells in peripheral blood differ between individuals and are stable for 18 months Cytometry B Clin Cytom. 2012 Jan; 82(1):18-25. . View in PubMed

Accelerated healing of diabetic wounds by NorLeu(3)-angiotensin (1-7) Expert Opin Investig Drugs. 2011 Nov; 20(11):1575-81. . View in PubMed

Gynaecological endoscopic evaluation of 4% icodextrin solution: a European, multicentre, double-blind, randomized study of the efficacy and safety in the reduction of de novo adhesions after laparoscopic gynaecological surgery Hum Reprod. 2011 Aug; 26(8):2015-27. . View in PubMed

Adept (icodextrin 4% solution) reduces adhesions after laparoscopic surgery for adhesiolysis: a double-blind, randomized, controlled study Fertil Steril. 2007 Nov; 88(5):1413-26. . View in PubMed

A modern biomaterial for adhesion prevention J Biomed Mater Res B Appl Biomater. 2007 Apr; 81(1):239-50. . View in PubMed

Clinical evaluation of endometriosis and differential response to surgical therapy with and without application of Oxiplex/AP* adhesion barrier gel Fertil Steril. 2007 Mar; 87(3):485-9. . View in PubMed

Expression of intracellular filament, collagen, and collagenase genes in diabetic and normal skin after injury Wound Repair Regen. 2006 May-Jun; 14(3):298-305. . View in PubMed

Phase I/II dose escalation study of angiotensin 1-7 [A(1-7)] administered before and after chemotherapy in patients with newly diagnosed breast cancer Cancer Chemother Pharmacol. 2006 May; 57(5):559-68. . View in PubMed

Effect of NorLeu3-A(1-7) on scar formation over time after full-thickness incision injury in the rat Wound Repair Regen. 2005 May-Jun; 13(3):309-17. . View in PubMed

Clinical evaluation of a viscoelastic gel for reduction of adhesions following gynaecological surgery by laparoscopy in Europe Hum Reprod. 2005 Feb; 20(2):514-20. . View in PubMed

Histological evaluation of the effects of angiotensin peptides on wound repair in diabetic mice Exp Dermatol. 2003 Dec; 12(6):784-90. . View in PubMed

Effects of intraperitoneal 4% icodextrin solution on the healing of bowel anastomoses and laparotomy incisions in rabbits Colorectal Dis. 2003 Jul; 5(4):324-30. . View in PubMed

Acceleration of healing, reduction of fibrotic scar, and normalization of tissue architecture by an angiotensin analogue, NorLeu3-A(1-7) Plast Reconstr Surg. 2003 Mar; 111(3):1195-206. . View in PubMed

Effect of angiotensin II and angiotensin(1-7) on hematopoietic recovery after intravenous chemotherapy Cancer Chemother Pharmacol. 2003 Feb; 51(2):97-106. . View in PubMed

Accelerated recovery from irradiation injury by angiotensin peptides Cancer Chemother Pharmacol. 2002 May; 49(5):403-11. . View in PubMed

A randomized, controlled pilot study of the safety and efficacy of 4% icodextrin solution in the reduction of adhesions following laparoscopic gynaecological surgery Hum Reprod. 2002 Apr; 17(4):1031-8. . View in PubMed

Peritoneal repair and post-surgical adhesion formation Hum Reprod Update. 2001 Nov-Dec; 7(6):547-55. . View in PubMed

Development of angiotensin (1-7) as an agent to accelerate dermal repair Wound Repair Regen. 2001 May-Jun; 9(3):238-47. . View in PubMed

Development of a novel glucose polymer solution (icodextrin) for adhesion prevention: pre-clinical studies Hum Reprod. 2000 Aug; 15(8):1764-72. . View in PubMed

Angiotensin II increases host resistance to peritonitis Clin Diagn Lab Immunol. 2000 Jul; 7(4):635-40. . View in PubMed

Effect of oxiplex* films (PEO/CMC) on adhesion formation and reformation in rabbit models and on peritoneal infection in a rat model Fertil Steril. 2000 Apr; 73(4):831-8. . View in PubMed

A new model for experimental tendon adhesions in the chicken Ann Plast Surg. 2000 Feb; 44(2):205-10. . View in PubMed

Effect of angiotensin II on hematopoietic progenitor cell proliferation Stem Cells. 2000; 18(4):287-94. . View in PubMed

Angiotensin II improves random-flap viability in a rat model Ann Plast Surg. 1999 Mar; 42(3):313-9. . View in PubMed

Clinical evaluation of 05% ferric hyaluronate adhesion prevention gel for the reduction of adhesions following peritoneal cavity surgery: open-label pilot study. Hum Reprod. 1998 Jun; 13(6):1480-5. . View in PubMed

Evaluation of polyethylene glycol/polylactic acid films in the prevention of adhesions in the rabbit adhesion formation and reformation sidewall models Fertil Steril. 1998 Mar; 69(3):403-8. . View in PubMed

Histologic alterations in dermal repair after thermal injury effects of topical angiotensin II J Burn Care Rehabil. 1997 Sep-Oct; 18(5):381-8. . View in PubMed

Expression of cyclin protein after thermal skin injury in a guinea pig model J Burn Care Rehabil. 1997 Jul-Aug; 18(4):292-8. . View in PubMed

Clinical problem of intraperitoneal postsurgical adhesion formation following general surgery and the use of adhesion prevention barriers Surg Clin North Am. 1997 Jun; 77(3):671-88. . View in PubMed

Acceleration of dermal tissue repair by angiotensin II Wound Repair Regen. 1997 Apr-Jun; 5(2):175-83. . View in PubMed

Biochemical events in peritoneal tissue repair Eur J Surg Suppl. 1997; (577):10-6. . View in PubMed

Alterations of angiotensin II Receptor levels in sutured wounds in rat skin J Invest Surg. 1996 Nov-Dec; 9(6):447-53. . View in PubMed

Alterations of angiotensin II receptor levels in full-thickness excisional wounds in rat skin Wound Repair Regen. 1996 Jul-Sep; 4(3):363-7. . View in PubMed

Adhesion controversies: pelvic pain as a cause of adhesions, crystalloids in preventing them J Reprod Med. 1996 Jan; 41(1):19-26. . View in PubMed

Comparative efficacy of nonsteroidal anti-inflammatory drugs and anti-thromboxane agents in a rabbit adhesion-prevention model J Invest Surg. 1995 May-Jun; 8(3):187-94. . View in PubMed

Is peritoneal closure necessary? Obstet Gynecol Surv. 1994 Dec; 49(12):817-22.. View in PubMed

Modulation of postsurgical cell infiltration and fibrinolytic activity by tolmetin in two species J Surg Res. 1994 Apr; 56(4):314-25. . View in PubMed

Contemporary adhesion prevention Fertil Steril. 1994 Feb; 61(2):219-35. . View in PubMed

Efficacy of tolmetin sodium for adhesion prevention in rabbit and rat models J Surg Res. 1994 Jan; 56(1):67-71. . View in PubMed

Modulation of cytotoxic activity of resident macrophages by postsurgical macrophages J Surg Res. 1993 Oct; 55(4):397-403. . View in PubMed

Peritoneal lavage fluid protease levels after in vivo administration of tolmetin in hyaluronic acid J Surg Res. 1993 Oct; 55(4):451-6. . View in PubMed

Function of peritoneal exudate cells after abdominal surgery J Invest Surg. 1993 Jan-Feb; 6(1):9-23. . View in PubMed

Modulation of peritoneal re-epithelialization by postsurgical macrophages J Surg Res. 1992 Nov; 53(5):542-8. . View in PubMed

In vivo administration of tolmetin in hyaluronic acid modulates protease levels in postsurgical macrophage-conditioned media J Invest Surg. 1992 Oct-Dec; 5(4):285-96. . View in PubMed

Modulation of postsurgical macrophage function by early postsurgical polymorphonuclear leukocytes J Surg Res. 1992 Sep; 53(3):245-50. . View in PubMed

Enhanced follicle regulatory protein levels accompany reinitiation of ovulatory function after parturition Am J Obstet Gynecol. 1992 Jul; 167(1):158-62. . View in PubMed

Effects of interleukin-1 (IL-1) on postsurgical macrophage secretion of protease and protease inhibitor activities J Surg Res. 1992 Jan; 52(1):71-8. . View in PubMed

Effect of tolmetin sodium dihydrate on adhesion formation by intraperitoneal administration of antineoplastic agents Cancer Chemother Pharmacol. 1992; 29(3):248-51. . View in PubMed

Inhibition of postsurgical adhesions in a standardized rabbit model: IIIntraperitoneal treatment with heparin. Int J Fertil. 1991 Sep-Oct; 36(5):296-301. . View in PubMed

Immunocytochemical localization of follicle regulatory-protein (FRP) in testis Anat Rec. 1991 Sep; 231(1):101-6. . View in PubMed

Inhibition of postsurgical adhesions in a standardized rabbit model: intraperitoneal treatment with tissue plasminogen activator Int J Fertil. 1991 May-Jun; 36(3):172-7. . View in PubMed

Differential steroid and gonadotropin response by individual tertiary porcine follicles in vitroPossible physiologic role of atretic follicles. Biol Reprod. 1991 Mar; 44(3):461-8. . View in PubMed

Kinetics of interleukin-1 and tumor necrosis factor secretion by rabbit macrophages recovered from the peritoneal cavity after surgery J Invest Surg. 1991; 4(2):141-51. . View in PubMed

Adhesion reformation: reduction by the use of Interceed (TC7) plus heparin J Gynecol Surg. 1991; 7(1):1-6. . View in PubMed

Inhibition of postsurgical adhesions by liposomes containing nonsteroidal antiinflammatory drugs Int J Fertil. 1990 Sep-Oct; 35(5):315-20. . View in PubMed

Cytotoxic effects of cyclophosphamide in the mouse seminiferous epithelium: DNA flow cytometric and morphometric analysis Fundam Appl Toxicol. 1990 Jul; 15(1):44-52. . View in PubMed

Follicle regulatory protein: a novel marker for granulosa cell cancer patients Gynecol Oncol. 1990 Jun; 37(3):381-7. . View in PubMed

Granulosa cells from pig follicles of different sizes demonstrate maturational differences in their steroidogenic responses to FSH, calcium ionophore A23187, and phorbol diester J Reprod Fertil. 1990 May; 89(1):181-91. . View in PubMed

Intraperitoneal tolmetin prevents postsurgical adhesion formation in rabbits Int J Fertil. 1990 Jan-Feb; 35(1):40-5. . View in PubMed

Local regulatory factors controlling folliculogenesis in pigs J Reprod Fertil Suppl. 1990; 40:151-61. . View in PubMed

Concentrations of follicle regulatory protein, steroids and gonadotrophins in antral fluids from women stimulated with metrodin and hCG J Reprod Fertil. 1990 Jan; 88(1):389-97. . View in PubMed

Alteration of follicular steroid secretion and thecal morphology after in-vitro exposure of individual pig follicles to follicle regulatory protein J Reprod Fertil. 1989 Sep; 87(1):133-40. . View in PubMed

Kinetics of interleukin-1 secretion by murine macrophages recovered from the peritoneal cavity after surgery J Surg Res. 1989 Aug; 47(2):178-82. . View in PubMed

Intragonadal regulation of follicular maturation Endocr Rev. 1989 May; 10(2):205-29. . View in PubMed

Flow cytometric quantification of rat spermatogenic cells after hypophysectomy and gonadotropin treatment Biol Reprod. 1989 Mar; 40(3):623-34. . View in PubMed

Modulation of proline and glucosamine incorporation into tissue repair cells by peritoneal macrophages J Surg Res. 1989 Feb; 46(2):166-71. . View in PubMed

Mitogenic and protein synthetic activity of tissue repair cells: control by the postsurgical macrophage J Invest Surg. 1989; 2(2):169-80. . View in PubMed

Inhibition of ovarian cancer cell proliferation in vivo and incorporation of 3H-thymidine in vitro after follicle regulatory protein administration Obstet Gynecol. 1989 Jan; 73(1):66-74. . View in PubMed

Incorporation of thymidine by fibroblasts: evidence for complex regulation by postsurgical macrophages J Surg Res. 1988 Nov; 45(5):460-6. . View in PubMed

DNA flow cytometric analysis of mouse seminiferous epithelium Cytometry. 1988 Sep; 9(5):456-62. . View in PubMed

Localization of follicle regulatory protein in the porcine ovary J Histochem Cytochem. 1988 Jun; 36(6):589-95. . View in PubMed

Angiogenic, mitogenic, and chemotactic activity of human follicular fluid Am J Obstet Gynecol. 1988 May; 158(5):1207-14. . View in PubMed

Effects of tolmetin sodium dihydrate on normal and postsurgical peritoneal cell function Int J Immunopharmacol. 1988; 10(2):111-9. . View in PubMed

A postulated role for follicle regulatory protein in follicle selection Prog Clin Biol Res. 1988; 267:201-26. . View in PubMed

Effects of follicle regulatory protein on thecal aromatase and 3 beta-hydroxysteroid dehydrogenase activity in medium- and large-sized pig follicles J Reprod Fertil. 1988 Jan; 82(1):163-71. . View in PubMed

Mediation of post-surgical wound healing by macrophages Prog Clin Biol Res. 1988; 266:273-90. . View in PubMed

Plasminogen activator secretion in the rat seminiferous epithelium after hypophysectomy and gonadotropin treatment Arch Androl. 1988; 20(3):219-27. . View in PubMed

Development of an enzyme-linked immunoassay for follicle regulatory protein Prog Clin Biol Res. 1988; 285:221-36. . View in PubMed

Modulation of fibroblast proliferation by postsurgical macrophages J Surg Res. 1987 Dec; 43(6):513-20. . View in PubMed

Alteration of follicle regulatory protein levels in human reproductive disorders: anovulation Obstet Gynecol. 1987 Aug; 70(2):157-62. . View in PubMed

A postulated role for naturally occurring aromatase inhibitors in follicle selection J Steroid Biochem. 1987; 27(1-3):375-83. . View in PubMed

A model for sidewall adhesions in the rabbit: reduction by an absorbable barrier Microsurgery. 1987; 8(4):197-200. . View in PubMed

Levels of follicle regulatory protein in regular menstruating and amenorrheic patients Adv Exp Med Biol. 1987; 219:721-6. . View in PubMed

Adhesion reduction in the rabbit uterine horn model using an absorbable barrier, TC-7 J Reprod Med. 1987 Jan; 32(1):17-20. . View in PubMed

Ibuprofen inhibition of postsurgical adhesion formation: a time and dose response biochemical evaluation in rabbits J Surg Res. 1984 Feb; 36(2):115-24. . View in PubMed

Biochemical evaluation of postsurgical wound repair: prevention of intraperitoneal adhesion formation with ibuprofen J Surg Res. 1983 Mar; 34(3):219-26. . View in PubMed

Oxiplex reduces leg pain, back pain, and associated symptoms after lumbar discectomy Spine (Phila Pa 1976). 2012 Apr 15; 37(8):631-41. . View in PubMed

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