Keck School Faculty

Gregory Idos, MD
Gregory Idos, MD
Assistant Professor of Clinical Medicine
IRD 708 Off Campus Los Angeles
Having trained in Boston at Brigham and Women’s Hospital and Dana Farber Cancer Center under the direction of national experts, Dr. Idos has an extensive background in caring for patients with hereditary colorectal cancer syndromes, notably Lynch Syndrome and familial adenomatous polyposis (FAP). Currently, he works with Stephen Gruber MD, PhD, MPH, Director of USC Norris Comprehensive Cancer Center, as part of the Norris Cancer Genetics Clinic. The Cancer Genetics Clinic specializes in care for persons with a personal or family history of cancer who may benefit from genetic testing and counseling to understand and manage their risk of cancer.

In addition, Dr. Idos’ research interest is focused on the study of gastrointestinal cancer and cancer chemoprevention. Currently, he directs studies aimed at understanding the use of genetic information for the overall risk reduction and prevention of cancer.

Brigham and Women's Hospital, Harvard Medical School: Fellowship Teaching Award, 2009-2010

LAC+USC Medical Center: Senior Resident of the Year, 2008-2009

LAC+USC Medical Center: Intern of the Year, 2006-2007

Howard Hughes Medical Institute: Undergraduate Research Fellow, 1998-1999

A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice Nat Commun. 2019 Dec 12; 10(1):5681. . View in PubMed

Novel Circulating Tumor Cell Assay for Detection of Colorectal Adenomas and Cancer Clin Transl Gastroenterol. 2019 Oct; 10(10):e00088. . View in PubMed

Publisher Correction: Shared heritability and functional enrichment across six solid cancers Nat Commun. 2019 Sep 23; 10(1):4386. . View in PubMed

Novel Common Genetic Susceptibility Loci for Colorectal Cancer J Natl Cancer Inst. 2019 Feb 01; 111(2):146-157. . View in PubMed

Discovery of common and rare genetic risk variants for colorectal cancer Nat Genet. 2019 01; 51(1):76-87. . View in PubMed

Shared heritability and functional enrichment across six solid cancers Nat Commun. 2019 01 25; 10(1):431. . View in PubMed

When Should Patients Undergo Genetic Testing for Hereditary Colon Cancer Syndromes? Clin Gastroenterol Hepatol. 2018 02; 16(2):181-183.. View in PubMed

Cytidine monophosphate N-acetylneuraminic acid synthetase enhances invasion of human triple-negative breast cancer cells Onco Targets Ther. 2018; 11:6827-6838. . View in PubMed

Patient communication of cancer genetic test results in a diverse population Transl Behav Med. 2018 01 29; 8(1):85-94. . View in PubMed

DNA mismatch repair deficiency and hereditary syndromes in Latino patients with colorectal cancer Cancer. 2017 Oct 01; 123(19):3732-3743. . View in PubMed

Mental Illness Is Not Associated with Adherence to Colorectal Cancer Screening: Results from the California Health Interview Survey Dig Dis Sci. 2017 01; 62(1):224-234. . View in PubMed

Increased yield of actionable mutations using multi-gene panels to assess hereditary cancer susceptibility in an ethnically diverse clinical cohort Cancer Genet. 2016 Apr; 209(4):130-7. . View in PubMed

A novel BAP1 mutation is associated with melanocytic neoplasms and thyroid cancer Cancer Genet. 2016 Mar; 209(3):75-81. . View in PubMed

Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci Nat Commun. 2015 Oct 26; 6:8739. . View in PubMed

Genome-wide association study of colorectal cancer identifies six new susceptibility loci Nat Commun. 2015 Jul 07; 6:7138. . View in PubMed

Genetic markers of malignant transformation in intraductal papillary mucinous neoplasm of the pancreas: a meta-analysis Pancreas. 2012 Nov; 41(8):1195-205. . View in PubMed

Protein partners of C/EBPepsilon Exp Hematol. 2004 Dec; 32(12):1173-81. . View in PubMed

RARbeta2 is a candidate tumor suppressor gene in myelofibrosis with myeloid metaplasia Oncogene. 2004 Oct 14; 23(47):7846-53. . View in PubMed

Identification of interaction partners and substrates of the cyclin A1-CDK2 complex J Biol Chem. 2004 Aug 06; 279(32):33727-41. . View in PubMed

Successive increases in human cyclin A1 promoter activity during spermatogenesis in transgenic mice Int J Mol Med. 2003 Mar; 11(3):311-5. . View in PubMed

Cyclin A1 directly interacts with B-myb and cyclin A1/cdk2 phosphorylate B-myb at functionally important serine and threonine residues: tissue-specific regulation of B-myb function Blood. 2001 Apr 01; 97(7):2091-7. . View in PubMed

Cyclin E is the only cyclin-dependent kinase 2-associated cyclin that predicts metastasis and survival in early stage non-small cell lung cancer Cancer Res. 2001 Jan 15; 61(2):647-53. . View in PubMed

Methylation of the cyclin A1 promoter correlates with gene silencing in somatic cell lines, while tissue-specific expression of cyclin A1 is methylation independent Mol Cell Biol. 2000 May; 20(9):3316-29. . View in PubMed

c-myb transactivates the human cyclin A1 promoter and induces cyclin A1 gene expression Blood. 1999 Dec 15; 94(12):4255-62. . View in PubMed

Cloning of the cyclin A1 genomic structure and characterization of the promoter regionGC boxes are essential for cell cycle-regulated transcription of the cyclin A1 gene. J Biol Chem. 1999 Apr 16; 274(16):11220-8. . View in PubMed

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