Keck School Faculty

Hisham Abdel-Azim, MD
Hisham Abdel-Azim, MD
Associate Professor of Pediatrics (Clinical Scholar)
CHL Mail Stop 62 Off Campus Los Angeles

Diagnosis, grading, and treatment recommendations for children, adolescents, and young adults with sinusoidal obstructive syndrome: an international expert position statement Lancet Haematol. 2019 Dec 06. . View in PubMed

Strategies to generate functionally normal neutrophils to reduce infection and infection-related mortality in cancer chemotherapy Pharmacol Ther. 2019 Dec; 204:107403. . View in PubMed

Maintenance Tyrosine Kinase Inhibitors Following Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Myelogenous Leukemia: A Center for International Blood and Marrow Transplant Research Study Biol Blood Marrow Transplant. 2019 Oct 25. . View in PubMed

Choice of conditioning regimens for bone marrow transplantation in severe aplastic anemia Blood Adv. 2019 Oct 22; 3(20):3123-3131. . View in PubMed

Integrin Antibody Decreases Deformability of Patient-Derived Pre-B Acute Lymphocytic Leukemia Cells as Measured by High-Frequency Acoustic Tweezers J Ultrasound Med. 2019 Oct 21. . View in PubMed

Impact of T Cell Dose on Outcome of T Cell-Replete HLA-Matched Allogeneic Peripheral Blood Stem Cell Transplantation Biol Blood Marrow Transplant. 2019 Sep; 25(9):1875-1883. . View in PubMed

Lower Graft-versus-Host Disease and Relapse Risk in Post-Transplant Cyclophosphamide-Based Haploidentical versus Matched Sibling Donor Reduced-Intensity Conditioning Transplant for Hodgkin Lymphoma Biol Blood Marrow Transplant. 2019 Sep; 25(9):1859-1868. . View in PubMed

Bacterial blood stream infections (BSIs), particularly post-engraftment BSIs, are associated with increased mortality after allogeneic hematopoietic cell transplantation Bone Marrow Transplant. 2019 Aug; 54(8):1254-1265. . View in PubMed

Outcomes of haploidentical vs matched sibling transplantation for acute myeloid leukemia in first complete remission Blood Adv. 2019 Jun 25; 3(12):1826-1836. . View in PubMed

GRFS and CRFS in alternative donor hematopoietic cell transplantation for pediatric patients with acute leukemia Blood Adv. 2019 May 14; 3(9):1441-1449. . View in PubMed

Survival Trends in Infants Undergoing Allogeneic Hematopoietic Cell Transplant JAMA Pediatr. 2019 May 01; 173(5):e190081. . View in PubMed

Outcomes after Second Hematopoietic Cell Transplantation in Children and Young Adults with Relapsed Acute Leukemia Biol Blood Marrow Transplant. 2019 02; 25(2):301-306. . View in PubMed

Comparative Analysis of Calcineurin Inhibitor-Based Methotrexate and Mycophenolate Mofetil-Containing Regimens for Prevention of Graft-versus-Host Disease after Reduced-Intensity Conditioning Allogeneic Transplantation Biol Blood Marrow Transplant. 2019 01; 25(1):73-85. . View in PubMed

Management guidelines for paediatric patients receiving chimeric antigen receptor T cell therapy Nat Rev Clin Oncol. 2019 01; 16(1):45-63. . View in PubMed

The impact of the graft-versus-leukemia effect on survival in acute lymphoblastic leukemia Blood Adv. 2019 02 26; 3(4):670-680. . View in PubMed

Impact of cytogenetic abnormalities on outcomes of adult Philadelphia-negative acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation: a study by the Acute Leukemia Working Committee of the Center for International Blood and Marrow Transplant Research Haematologica. 2019 09 26. . View in PubMed

Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008 J Exp Clin Cancer Res. 2018 Mar 27; 37(1):67. . View in PubMed

Country-Level Macroeconomic Indicators Predict Early Post-Allogeneic Hematopoietic Cell Transplantation Survival in Acute Lymphoblastic Leukemia: A CIBMTR Analysis Biol Blood Marrow Transplant. 2018 09; 24(9):1928-1935. . View in PubMed

Donor body mass index does not predict graft versus host disease following hematopoietic cell transplantation Bone Marrow Transplant. 2018 07; 53(7):932-937. . View in PubMed

Influence of Age on Acute and Chronic GVHD in Children Undergoing HLA-Identical Sibling Bone Marrow Transplantation for Acute Leukemia: Implications for Prophylaxis Biol Blood Marrow Transplant. 2018 03; 24(3):521-528. . View in PubMed

Donor Experiences of Second Marrow or Peripheral Blood Stem Cell Collection Mirror the First, but CD34+ Yields Are Less Biol Blood Marrow Transplant. 2018 01; 24(1):175-184. . View in PubMed

Characterizing Deformability of Drug Resistant Patient-Derived Acute Lymphoblastic Leukemia (ALL) Cells Using Acoustic Tweezers Sci Rep. 2018 10 24; 8(1):15708. . View in PubMed

B-cell differentiation and IL-21 response in IL2RG/JAK3 SCID patients after hematopoietic stem cell transplantation Blood. 2018 06 28; 131(26):2967-2977. . View in PubMed

SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery Blood. 2018 10 25; 132(17):1737-1749. . View in PubMed

Pre-B acute lymphoblastic leukemia expresses cell surface nucleolin as a 9-O-acetylated sialoglycoprotein Sci Rep. 2018 11 21; 8(1):17174. . View in PubMed

Outcomes following autologous hematopoietic stem cell transplant for patients with relapsed Wilms' tumor: a CIBMTR retrospective analysis Bone Marrow Transplant. 2017 Nov; 52(11):1549-1555. . View in PubMed

The PI3Kd Inhibitor Idelalisib Inhibits Homing in an in Vitro and in Vivo Model of B ALL Cancers (Basel). 2017 Sep 10; 9(9). . View in PubMed

Personalized Prognostic Risk Score for Long-Term Survival for Children with Acute Leukemia after Allogeneic Transplantation Biol Blood Marrow Transplant. 2017 Sep; 23(9):1523-1530. . View in PubMed

Humoral Immune Reconstitution Kinetics after Allogeneic Hematopoietic Stem Cell Transplantation in Children: A Maturation Block of IgM Memory B Cells May Lead to Impaired Antibody Immune Reconstitution Biol Blood Marrow Transplant. 2017 Sep; 23(9):1437-1446. . View in PubMed

Hematopoietic Stem Cell Transplantation Activity in Pediatric Cancer between 2008 and 2014 in the United States: A Center for International Blood and Marrow Transplant Research Report Biol Blood Marrow Transplant. 2017 Aug; 23(8):1342-1349. . View in PubMed

Phase I Study of Clofarabine and 2-Gy Total Body Irradiation as a Nonmyeloablative Preparative Regimen for Hematopoietic Stem Cell Transplantation in Pediatric Patients with Hematologic Malignancies: A Therapeutic Advances in Childhood Leukemia Consortium Study Biol Blood Marrow Transplant. 2017 Jul; 23(7):1134-1141. . View in PubMed

Role of aß T Cell Depletion in Prevention of Graft versus Host Disease Biomedicines. 2017 Jun 26; 5(3). . View in PubMed

Outcomes after Umbilical Cord Blood Transplantation for Myelodysplastic Syndromes Biol Blood Marrow Transplant. 2017 Jun; 23(6):971-979. . View in PubMed

GvHD after umbilical cord blood transplantation for acute leukemia: an analysis of risk factors and effect on outcomes Bone Marrow Transplant. 2017 Mar; 52(3):400-408. . View in PubMed

Clinical risks and healthcare utilization of hematopoietic cell transplantation for sickle cell disease in the USA using merged databases Haematologica. 2017 11; 102(11):1823-1832. . View in PubMed

Reply: T-Cell Acute Lymphoblastic Leukemia, Minimal Residual Disease, and Lymphocyte Recovery Pediatr Blood Cancer. 2016 May; 63(5):945. . View in PubMed

The incidence, mortality and timing of Pneumocystis jiroveci pneumonia after hematopoietic cell transplantation: a CIBMTR analysis Bone Marrow Transplant. 2016 Apr; 51(4):573-80. . View in PubMed

Transcriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacetylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B-cell Acute Lymphoblastic Leukemia J Biol Chem. 2016 Feb 19; 291(8):4004-18. . View in PubMed

Am80-GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia-associated infection and mortality EMBO Mol Med. 2016 11; 8(11):1340-1359. . View in PubMed

Human leukocyte antigen supertype matching after myeloablative hematopoietic cell transplantation with 7/8 matched unrelated donor allografts: a report from the Center for International Blood and Marrow Transplant Research Haematologica. 2016 10; 101(10):1267-1274. . View in PubMed

Infection Rates among Acute Leukemia Patients Receiving Alternative Donor Hematopoietic Cell Transplantation Biol Blood Marrow Transplant. 2016 09; 22(9):1636-1645. . View in PubMed

Outcomes of Allogeneic Hematopoietic Cell Transplantation in Children and Young Adults with Chronic Myeloid Leukemia: A CIBMTR Cohort Analysis Biol Blood Marrow Transplant. 2016 06; 22(6):1056-1064. . View in PubMed

Transplant Outcomes for Children with T Cell Acute Lymphoblastic Leukemia in Second Remission: A Report from the Center for International Blood and Marrow Transplant Research Biol Blood Marrow Transplant. 2015 Dec; 21(12):2154-2159. . View in PubMed

A prognostic model predicting autologous transplantation outcomes in children, adolescents and young adults with Hodgkin lymphoma Bone Marrow Transplant. 2015 Nov; 50(11):1416-23. . View in PubMed

Unrelated donor hematopoietic stem cell transplantation for the treatment of non-malignant genetic diseases: An alemtuzumab based regimen is associated with cure of clinical disease; earlier clearance of alemtuzumab may be associated with graft rejection Am J Hematol. 2015 Nov; 90(11):1021-6. . View in PubMed

End of induction minimal residual disease alone is not a useful determinant for risk stratified therapy in pediatric T-cell acute lymphoblastic leukemia Pediatr Blood Cancer. 2015 Nov; 62(11):2040-3. . View in PubMed

Analysis of the Effect of Race, Socioeconomic Status, and Center Size on Unrelated National Marrow Donor Program Donor Outcomes: Donor Toxicities Are More Common at Low-Volume Bone Marrow Collection Centers Biol Blood Marrow Transplant. 2015 Oct; 21(10):1830-8. . View in PubMed

Second Allogeneic Hematopoietic Cell Transplantation for Patients with Fanconi Anemia and Bone Marrow Failure Biol Blood Marrow Transplant. 2015 Oct; 21(10):1790-5. . View in PubMed

Graft versus tumor effect in the brain of a child with recurrent metastatic medulloblastoma Pediatr Blood Cancer. 2015 Sep; 62(9):1667-9. . View in PubMed

Improved outcomes associated with hematopoietic stem cell transplantation for patients with juvenile myelomonocytic leukemia Blood. 2015 Jul 23; 126(4):561-2. . View in PubMed

Transplantation Outcomes for Children with Hypodiploid Acute Lymphoblastic Leukemia Biol Blood Marrow Transplant. 2015 Jul; 21(7):1273-7. . View in PubMed

Low-dose total-body irradiation and alemtuzumab-based reduced-intensity conditioning regimen results in durable engraftment and correction of clinical disease among children with chronic granulomatous disease Pediatr Transplant. 2015 Jun; 19(4):408-12. . View in PubMed

B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3 Oncotarget. 2015 May 10; 6(13):11378-94. . View in PubMed

Successful bone marrow transplantation of an adolescent young adult female with pregnancy-associated aplastic anemia J Pediatr Hematol Oncol. 2015 May; 37(4):319-21. . View in PubMed

A survey of infectious disease clinical practices among pediatric blood and marrow transplant programs in the United States Pediatr Blood Cancer. 2015 Apr; 62(4):731-5. . View in PubMed

Cytotoxicity of CD56-positive lymphocytes against autologous B-cell precursor acute lymphoblastic leukemia cells Leukemia. 2015 Apr; 29(4):788-97. . View in PubMed

A reduced-toxicity regimen is associated with durable engraftment and clinical cure of nonmalignant genetic diseases among children undergoing blood and marrow transplantation with an HLA-matched related donor Biol Blood Marrow Transplant. 2015 Mar; 21(3):440-4. . View in PubMed

Potential of autologous NK cell therapy to eradicate leukemia: "Education is [not] the best provision for old age" -Aristotle Oncoimmunology. 2015 Feb; 4(2):e984549. . View in PubMed

Phosphoflow-Based Evaluation of Mek Inhibitors as Small-Molecule Therapeutics for B-Cell Precursor Acute Lymphoblastic Leukemia PLoS One. 2015; 10(9):e0137917. . View in PubMed

Obesity is associated with residual leukemia following induction therapy for childhood B-precursor acute lymphoblastic leukemia Blood. 2014 Dec 18; 124(26):3932-8. . View in PubMed

Bortezomib for effective treatment of a child with refractory autoimmune hemolytic anemia post allogeneic hematopoietic stem cell transplant Pediatr Blood Cancer. 2014 Dec; 61(12):2324-5. . View in PubMed

Overcoming psychosocial and developmental barriers to blood and marrow transplantation (BMT) in an adolescent/young adult (AYA) transgender patient with chronic myelogenous leukemia Pediatr Hematol Oncol. 2014 Nov; 31(8):765-7. . View in PubMed

Immunologic resolution of human chronic graft-versus-host disease Biol Blood Marrow Transplant. 2014 Oct; 20(10):1508-15. . View in PubMed

Effector-mediated eradication of precursor B acute lymphoblastic leukemia with a novel Fc-engineered monoclonal antibody targeting the BAFF-R Mol Cancer Ther. 2014 Jun; 13(6):1567-77. . View in PubMed

J Immunol. 2014 Jun 01; 192(11):5050-8. . View in PubMed

Transplantation for children with acute myeloid leukemia: a comparison of outcomes with reduced intensity and myeloablative regimens Blood. 2014 Mar 06; 123(10):1615-20. . View in PubMed

Galectin-3 in pre-B acute lymphoblastic leukemia Leukemia. 2013 Dec; 27(12):2385-8. . View in PubMed

ß-globin gene transfer to human bone marrow for sickle cell disease J Clin Invest. 2013 Jul 01. . View in PubMed

Circulating hematopoietic and endothelial progenitor cells in newborn infants: effects of gestational age, postnatal age and clinical stress in the first 3 weeks of life Early Hum Dev. 2013 Jun; 89(6):411-8. . View in PubMed

O-acetylated N-acetylneuraminic acid as a novel target for therapy in human pre-B acute lymphoblastic leukemia J Exp Med. 2013 Apr 08; 210(4):805-19. . View in PubMed

Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans Blood. 2012 Nov 01; 120(18):3635-46. . View in PubMed

Clinical and genetic heterogeneity in Omenn syndrome and severe combined immune deficiency Pediatr Transplant. 2009 Mar; 13(2):244-50. . View in PubMed

Pre- and post-natal treatment of hemophagocytic lymphohistiocytosis Pediatr Blood Cancer. 2009 Jan; 52(1):139-42. . View in PubMed

Expansion of multipotent and lymphoid-committed human progenitors through intracellular dimerization of Mpl Blood. 2008 Apr 15; 111(8):4064-74. . View in PubMed

Congenital bilateral upper eyelid coloboma J Perinatol. 2003 Mar; 23(2):166-7. . View in PubMed

Risk factors in intermediate and high-grade non-Hodgkin's lymphomas of adults: a need for a new staging system Anticancer Drugs. 1991 Aug; 2(4):383-8. . View in PubMed

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