Holly Ann Muir, MD

Chair and Professor, Department of Anesthesiology

Vladimir Zelman, MD, PhD, Professor and Chair in Anesthesiology

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Holly Muir, MD, earned her medical doctorate from Dalhousie University in Halifax, Nova Scotia, where she also completed her residency training in anesthesia. Following her residency, she matriculated to University of Pennsylvania to pursue a fellowship in obstetric anesthesia and then returned to Halifax where she served on the faculty at Dalhousie. There, she served as the residency program director, the provincial QI director for anesthesia and the chief of the obstetrics service for the IWK Hospital. She was recruited to the Duke University School of Medicine in 1998 to serve as chief of the Division of Women’s Anesthesia. In 2003, she was invited to serve as the vice chair of clinical operations and medical director of perioperative services.

In January 2017, Muir was named chair of the Department of Anesthesiology at the Keck School of Medicine of USC.


  • Oxidative stress in critical care and vitamins supplement therapy: “a beneficial care enhancing” Eur Rev Med Pharmacol Sci. 2019 Sep; 23(17):7703-7712. . View in PubMed
  • Non-infarctual ST elevation and acute cardiopulmonary failure in carbon monoxide poisoning: a case report Eur Rev Med Pharmacol Sci. 2019 Aug; 23(16):7128-7134. . View in PubMed
  • Front Public Health. 2017; 5:78. . View in PubMed
  • Teaching neuraxial anesthesia techniques for obstetric care in a Ghanaian referral hospital: achievements and obstacles Anesth Analg. 2015 Jun; 120(6):1317-22. . View in PubMed
  • A prospective evaluation of the incidence of adverse events in nurse-administered moderate sedation guided by sedation scores or Bispectral Index Anesth Analg. 2014 Jul; 119(1):43-48. . View in PubMed
  • A retrospective assessment of the incidence of respiratory depression after neuraxial morphine administration for postcesarean delivery analgesia Anesth Analg. 2013 Dec; 117(6):1368-70. . View in PubMed
  • Pharmacologic intervention for managing uterine atony and related maternal hemorrhage: what is the most effective drug dose? Can J Anaesth. 2013 Nov; 60(11):1047-53.. View in PubMed
  • A double-blind, placebo-controlled trial of four fixed rate infusion regimens of phenylephrine for hemodynamic support during spinal anesthesia for cesarean delivery Anesth Analg. 2010 Nov; 111(5):1221-9. . View in PubMed
  • A survey of the management of spinal-induced hypotension for scheduled cesarean delivery Int J Obstet Anesth. 2009 Oct; 18(4):356-61. . View in PubMed
  • Multidisciplinary management of placenta percreta complicated by embolic phenomena Int J Obstet Anesth. 2008 Jul; 17(3):262-6. . View in PubMed
  • Brief report: a randomized controlled trial of Synera versus lidocaine for epidural needle insertion in labouring parturients Can J Anaesth. 2008 Mar; 55(3):168-71. . View in PubMed
  • The management of Cesarean delivery in a parturient with paroxysmal nocturnal hemoglobinuria complicated by severe preeclampsia Can J Anaesth. 2007 Aug; 54(8):646-51. . View in PubMed
  • Critical arrhythmia associated with pulmonary artery catheterization in a parturient with severe pulmonary hypertension Can J Anaesth. 2007 Jun; 54(6):486-7. . View in PubMed
  • Use of a modifier reduces inconsistency in the American Society of Anesthesiologists Physical Status Classification in parturients Anesth Analg. 2006 Apr; 102(4):1231-3. . View in PubMed
  • Reversible nitrous oxide myelopathy and a polymorphism in the gene encoding 5,10-methylenetetrahydrofolate reductase Br J Anaesth. 2006 Feb; 96(2):222-5. . View in PubMed
  • Tracheal intubation without muscle relaxants for caesarean section in patients with spinal muscular atrophy Int J Obstet Anesth. 2005 Oct; 14(4):366-7. . View in PubMed
  • Perioperative anesthetic management for Cesarean section of a parturient with gestational diabetes insipidus Can J Anaesth. 2005 Aug-Sep; 52(7):733-6. . View in PubMed
  • Single-dose, sustained-release epidural morphine in the management of postoperative pain after elective cesarean delivery: results of a multicenter randomized controlled study Anesth Analg. 2005 Apr; 100(4):1150-1158. . View in PubMed
  • Dural ectasia: a likely cause of inadequate spinal anaesthesia in two parturients with Marfan’s syndrome Br J Anaesth. 2005 Apr; 94(4):500-4. . View in PubMed
  • Intrathecal morphine for analgesia after postpartum bilateral tubal ligation Anesth Analg. 2005 Jan; 100(1):239-243. . View in PubMed
  • A multicenter randomized controlled trial comparing patient-controlled epidural with intravenous analgesia for pain relief in labor Anesth Analg. 2004 Nov; 99(5):1532-1538. . View in PubMed
  • Is the minimum local analgesic concentration method robust enough? Anesthesiology. 2004 Aug; 101(2):550; author reply 550-1.. View in PubMed
  • Anesthesia for cesarean section in a patient with spinal muscular atrophy J Clin Anesth. 2004 May; 16(3):217-9. . View in PubMed
  • A multicenter, randomized, controlled trial comparing bupivacaine with ropivacaine for labor analgesia Anesthesiology. 2003 Jun; 98(6):1431-5. . View in PubMed
  • Anesthetic management of a ventilator-dependent parturient with the King-Denborough syndrome Can J Anaesth. 2003 Jun-Jul; 50(6):589-92. . View in PubMed
  • Effectiveness of nurses as providers of birth labor support in North American hospitals: a randomized controlled trial JAMA. 2002 Sep 18; 288(11):1373-81. . View in PubMed
  • New techniques and drugs for epidural labor analgesia Semin Perinatol. 2002 Apr; 26(2):99-108. . View in PubMed
  • Comparison of epidural anaesthesia with ropivacaine 05% and bupivacaine 0. 5% for caesarean section. Can J Anaesth. 1998 Nov; 45(11):1066-71. . View in PubMed
  • The unanticipated difficult airway with recommendations for management Can J Anaesth. 1998 Aug; 45(8):757-76. . View in PubMed
  • Does epidural analgesia during labour affect the neonate? Curr Opin Anaesthesiol. 1998 Jun; 11(3):271-3.. View in PubMed
  • Double-blind comparison of epidural ropivacaine 025% and bupivacaine 0. 25%, for the relief of childbirth pain. Can J Anaesth. 1997 Jun; 44(6):599-604. . View in PubMed
  • Continuous epidural ropivacaine 02% for analgesia after lower abdominal surgery. Anesth Analg. 1997 Apr; 84(4):784-90. . View in PubMed