Hsiao Chuan Liu, PhD

Dr. Hsiao Chuan Liu’s research interests lie in acoustic radiation force-based optical coherence elastography technique, which explores micromechanics of tissues and scaffolds associated with various diseases and tissue engineering, ultrasound shear wave elastography, development of new optical & acoustic integrated system and algorithm, acoustic tweezers to study cellular biomechanical properties, wave theory and numerical simulations, and ultrasound & optical translational development to clinical applications.

• 23rd Annual USC Pathology Conference: Best Paper Award, 2020
• SPIE Medical Imaging: Cum Laude Poster Award, 2017
• University of Southern California: 4-year Global USC Fellowship, 2015
• Korean Society of Ultrasound in Medicine: International Grant Award, 2015
• Korean Society of Ultrasound in Medicine: Best Poster Award, 2014
• Korean Society of Ultrasound in Medicine: International Grant Award, 2014
• Korean Congress of Radiology: International Grant Award, 2012
• Korean Congress of Radiology: International Grant Award, 2011

• Acoustic radiation force-induced longitudinal shear wave for ultrasound-based viscoelastic evaluation Ultrasonics. 2024 Jun 22; 142:107389. . View in PubMed
• Wearable bioadhesive ultrasound shear wave elastography Sci Adv. 2024 Feb 09; 10(6):eadk8426. . View in PubMed
• Acoustic Force Elastography Microscopy IEEE Trans Biomed Eng. 2023 Mar; 70(3):841-852. . View in PubMed
• Measurement of wave propagation through a tube using dual transducers for elastography in arteries Phys Med Biol. 2022 Nov 11; 67(22). . View in PubMed
• Bioadhesive ultrasound for long-term continuous imaging of diverse organs Science. 2022 Jul 29; 377(6605):517-523. . View in PubMed
• In vitro and in vivo effects of AVA4746, a novel competitive antagonist of the ligand binding of VLA-4, in B-cell acute lymphoblastic leukemia Exp Ther Med. 2022 Jan; 23(1):47. . View in PubMed
• Evaluation of Robustness of Local Phase Velocity Imaging in Homogenous Tissue-Mimicking Phantoms Ultrasound Med Biol. 2021 Dec; 47(12):3514-3528. . View in PubMed
• Arsenic trioxide and all-trans retinoic acid in the treatment of children with newly diagnosed acute promyelocytic leukemia Leuk Lymphoma. 2021 May; 62(5):1267-1270. . View in PubMed
• Optical coherence viscometry Appl Phys Lett. 2021 Apr 19; 118(16):164102. . View in PubMed
• Characterizing thrombus with multiple red blood cell compositions by optical coherence tomography attenuation coefficient J Biophotonics. 2021 Mar; 14(3):e202000364. . View in PubMed
• Two-dimensional (2D) dynamic vibration optical coherence elastography (DV-OCE) for evaluating mechanical properties: a potential application in tissue engineering Biomed Opt Express. 2021 Mar 01; 12(3):1217-1235. . View in PubMed
• Characterizing blood clots using acoustic radiation force optical coherence elastography and ultrasound shear wave elastography Phys Med Biol. 2021 Jan 26; 66(3):035013. . View in PubMed
• Four-dimensional (4D) phase velocity optical coherence elastography in heterogeneous materials and biological tissue Biomed Opt Express. 2020 Jul 01; 11(7):3795-3817. . View in PubMed
• Fluid surface tension evaluation using capillary wave measurement with optical coherence tomography AIP Adv. 2020 May; 10(5):055121. . View in PubMed
• Acoustic radiation force optical coherence elastography for evaluating mechanical properties of soft condensed matters and its biological applications J Biophotonics. 2020 Mar; 13(3):e201960134. . View in PubMed
• Integrin Antibody Decreases Deformability of Patient-Derived Pre-B Acute Lymphocytic Leukemia Cells as Measured by High-Frequency Acoustic Tweezers J Ultrasound Med. 2020 Mar; 39(3):589-595. . View in PubMed
• Optical coherence tomography for evaluating capillary waves in blood and plasma Biomed Opt Express. 2020 Feb 01; 11(2):1092-1106. . View in PubMed
• Investigation of cell mechanics using single-beam acoustic tweezers as a versatile tool for the diagnosis and treatment of highly invasive breast cancer cell lines: an in vitro study Microsyst Nanoeng. 2020; 6:39. . View in PubMed
• Characterizing the Motility of Chemotherapeutics-Treated Acute Lymphoblastic Leukemia Cells by Time-Lapse Imaging Cells. 2020 06 16; 9(6). . View in PubMed
• Characterizing Deformability of Drug Resistant Patient-Derived Acute Lymphoblastic Leukemia (ALL) Cells Using Acoustic Tweezers Sci Rep. 2018 10 24; 8(1):15708. . View in PubMed
• Single-Beam Acoustic Trapping of Red Blood Cells and Polystyrene Microspheres in Flowing Red Blood Cell Saline and Plasma Suspensions Ultrasound Med Biol. 2017 04; 43(4):852-859. . View in PubMed
• Effects of CD49d-targeted antisense-oligonucleotide on a4 integrin expression and function of acute lymphoblastic leukemia cells: Results of in vitro and in vivo studies PLoS One. 2017; 12(11):e0187684. . View in PubMed
• Long-term secular trend of skeletal maturation of Taiwanese children between agricultural (1960s) and contemporary (after 2000s) generations using the Tanner-Whitehouse 3 (TW3) method J Pediatr Endocrinol Metab. 2013; 26(3-4):231-7. . View in PubMed
• Simplified radius, ulna, and short bone-age assessment procedure using grouped-Tanner-Whitehouse method Pediatr Int. 2011 Aug; 53(4):567-75. . View in PubMed
• Interrelationship of carpal angle and bone age in children of different generations: a retrospective study J Pediatr Endocrinol Metab. 2011; 24(11-12):1015-8. . View in PubMed
• A fuzzy-based growth model with principle component analysis selection for carpal bone-age assessment Med Biol Eng Comput. 2010 Jun; 48(6):579-88. . View in PubMed
• Turner syndrome phalangeal screening based on a two-stage linear regression concept Pediatr Int. 2009 Aug; 51(4):453-9. . View in PubMed
• Computer-aided diagnosis of peripheral soft tissue masses based on ultrasound imaging Comput Med Imaging Graph. 2009 Jul; 33(5):408-13. . View in PubMed

• Wiemels, Joseph
• Gaynon, Paul
• Bhojwani, Deepa
• Zhou, Qifa
• Orgel, Etan
• Kim, Yong-Mi
• de Smith, Adam