Keck School Faculty

Kinji Asahina, PhD
Kinji Asahina, PhD
Associate Professor of Research Pathology
MMR402 1333 San Pablo Street Health Sciences Campus Los Angeles

Moderate Alcohol Intake Promotes Pancreatic Ductal Adenocarcinoma Development in Mice Expressing Oncogenic Kras Am J Physiol Gastrointest Liver Physiol. 2019 Nov 25. . View in PubMed

Development of Capsular Fibrosis Beneath the Liver Surface in Humans and Mice Hepatology. 2019 Jun 17. . View in PubMed

Isolation of a unique hepatic stellate cell population expressing integrin a8 from embryonic mouse livers Dev Dyn. 2018 Jun; 247(6):867-881. . View in PubMed

Hepatic Prominin-1 expression is associated with biliary fibrosis Surgery. 2017 05; 161(5):1266-1272. . View in PubMed

Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers J Hepatol. 2016 May; 64(5):1137-1146. . View in PubMed

The Role of Mesothelial Cells in Liver Development, Injury, and Regeneration Gut Liver. 2016 Mar; 10(2):166-76. . View in PubMed

Role of TGF-ß signaling in differentiation of mesothelial cells to vitamin A-poor hepatic stellate cells in liver fibrosis Am J Physiol Gastrointest Liver Physiol. 2016 Feb 15; 310(4):G262-72. . View in PubMed

Activation of hepatic stellate cell in Pten null liver injury model Fibrogenesis Tissue Repair. 2016; 9:8. . View in PubMed

Myofibroblastic Conversion and Regeneration of Mesothelial Cells in Peritoneal and Liver Fibrosis Am J Pathol. 2015 Dec; 185(12):3258-73. . View in PubMed

MACS Isolation and Culture of Mouse Liver Mesothelial Cells Bio Protoc. 2015 Jul 05; 3(13). . View in PubMed

Expansion of prominin-1-expressing cells in association with fibrosis of biliary atresia Hepatology. 2014 Sep; 60(3):941-53. . View in PubMed

TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis J Clin Invest. 2014 Aug; 124(8):3566-78. . View in PubMed

Mesodermal mesenchymal cells give rise to myofibroblasts, but not epithelial cells, in mouse liver injury Hepatology. 2014 Jul; 60(1):311-22. . View in PubMed

Hepatic stellate cells in liver development, regeneration, and cancer J Clin Invest. 2013 May; 123(5):1902-10. . View in PubMed

Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver injury Proc Natl Acad Sci U S A. 2013 Feb 05; 110(6):2324-9. . View in PubMed

Hepatology. 2012 Apr; 55(4):1271-81. . View in PubMed

Hepatic stellate cell-derived delta-like homolog 1 (DLK1) protein in liver regeneration J Biol Chem. 2012 Mar 23; 287(13):10355-67. . View in PubMed

Hepatic stellate cells mediate differentiation of dendritic cells from monocytes J Med Dent Sci. 2012 Mar 13; 59(1):43-52. . View in PubMed

Morphogens and hepatic stellate cell fate regulation in chronic liver disease J Gastroenterol Hepatol. 2012 Mar; 27 Suppl 2:94-8. . View in PubMed

Hepatic stellate cell progenitor cells J Gastroenterol Hepatol. 2012 Mar; 27 Suppl 2:80-4. . View in PubMed

15th International Symposium on Cells of the Hepatic Sinusoid, 2010 Liver Int. 2011 Jul; 31(6):762-72. . View in PubMed

Epigenetic cell fate regulation of hepatic stellate cells Hepatol Res. 2011 Jul; 41(7):675-82. . View in PubMed

Septum transversum-derived mesothelium gives rise to hepatic stellate cells and perivascular mesenchymal cells in developing mouse liver Hepatology. 2011 Mar; 53(3):983-95. . View in PubMed

A novel method of mouse ex utero transplantation of hepatic progenitor cells into the fetal liver Biochem Biophys Res Commun. 2009 Apr 03; 381(2):276-82. . View in PubMed

Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development Hepatology. 2009 Mar; 49(3):998-1011. . View in PubMed

Effect of poly(N-vinyl-pyrrolidone)-block-poly(D,L-lactide) as coating agent on the opsonization, phagocytosis, and pharmacokinetics of biodegradable nanoparticles Biomacromolecules. 2009 Feb 09; 10(2):408-16. . View in PubMed

Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog Proc Natl Acad Sci U S A. 2009 Feb 03; 106(5):1548-53. . View in PubMed

Vascular endothelial growth factor promotes proliferation and function of hepatocyte-like cells in embryoid bodies formed from mouse embryonic stem cells J Hepatol. 2008 Jun; 48(6):962-73. . View in PubMed

Involvement of CCAAT/enhancer binding protein-beta (C/EBPbeta) in epigenetic regulation of mouse methionine adenosyltransferase 1A gene expression Int J Biochem Cell Biol. 2008; 40(9):1956-69. . View in PubMed

Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis Am J Physiol Gastrointest Liver Physiol. 2008 Jan; 294(1):G39-49. . View in PubMed

Hepatic progenitor cells in the mouse extrahepatic bile duct after a bile duct ligation Stem Cells Dev. 2007 Dec; 16(6):979-87. . View in PubMed

Developmental pluripotency-associated 4 (DPPA4) localized in active chromatin inhibits mouse embryonic stem cell differentiation into a primitive ectoderm lineage J Biol Chem. 2007 Nov 09; 282(45):33034-42. . View in PubMed

Characterization of vitamin A-storing cells in mouse fibrous kidneys using Cygb/STAP as a marker of activated stellate cells Arch Histol Cytol. 2007 Jul; 70(2):95-106. . View in PubMed

Twist relates to tubular epithelial-mesenchymal transition and interstitial fibrogenesis in the obstructed kidney J Histochem Cytochem. 2007 Jul; 55(7):661-73. . View in PubMed

Identification of vitamin A-free cells in a stellate cell-enriched fraction of normal rat liver as myofibroblasts Histochem Cell Biol. 2007 Feb; 127(2):161-74. . View in PubMed

Human cord blood cells transplanted into chronically damaged liver exhibit similar characteristics to functional hepatocytes Transplant Proc. 2007 Jan-Feb; 39(1):240-3. . View in PubMed

Embryonic stem cells: hepatic differentiation and regenerative medicine for the treatment of liver disease Curr Stem Cell Res Ther. 2006 May; 1(2):139-56. . View in PubMed

Multiplicative mononuclear small hepatocytes in adult rat liver: their isolation as a homogeneous population and localization to periportal zone Biochem Biophys Res Commun. 2006 Apr 21; 342(4):1160-7. . View in PubMed

Differential involvement of phosphatidylinositol 3-kinase-related protein kinases in hyperphosphorylation of replication protein A2 in response to replication-mediated DNA double-strand breaks Genes Cells. 2006 Mar; 11(3):237-46. . View in PubMed

Generation of hybrid hepatocytes by cell fusion from monkey embryoid body cells in the injured mouse liver Histochem Cell Biol. 2006 Mar; 125(3):247-57. . View in PubMed

Phosphorylation of histone H2AX at M phase in human cells without DNA damage response Biochem Biophys Res Commun. 2005 Oct 28; 336(3):807-12. . View in PubMed

Efficient in vivo xenogeneic retroviral vector-mediated gene transduction into human hepatocytes Hum Gene Ther. 2005 Oct; 16(10):1168-74. . View in PubMed

Enrichment of hepatocytes differentiated from mouse embryonic stem cells as a transplantable source Transplantation. 2005 Mar 15; 79(5):550-7. . View in PubMed

Isolation of hepatocyte-like cells from mouse embryoid body cells Transplant Proc. 2005 Jan-Feb; 37(1):299-300. . View in PubMed

Hepatocyte differentiation from embryonic stem cells and umbilical cord blood cells J Hepatobiliary Pancreat Surg. 2005; 12(3):196-202. . View in PubMed

Teratoma formation and hepatocyte differentiation in mouse liver transplanted with mouse embryonic stem cell-derived embryoid bodies Transplant Proc. 2005 Jan-Feb; 37(1):285-6. . View in PubMed

Expression of the liver-specific gene Cyp7a1 reveals hepatic differentiation in embryoid bodies derived from mouse embryonic stem cells Genes Cells. 2004 Dec; 9(12):1297-308. . View in PubMed

Near completely humanized liver in mice shows human-type metabolic responses to drugs Am J Pathol. 2004 Sep; 165(3):901-12. . View in PubMed

Characterization of human stellate cell activation-associated protein and its expression in human liver Biochim Biophys Acta. 2002 Sep 27; 1577(3):471-5. . View in PubMed

Pleiotrophin/heparin-binding growth-associated molecule as a mitogen of rat hepatocytes and its role in regeneration and development of liver Am J Pathol. 2002 Jun; 160(6):2191-205. . View in PubMed

Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells J Biol Chem. 2001 Jul 06; 276(27):25318-23. . View in PubMed

Developmentally and regionally regulated participation of epidermal cells in the formation of collagen lamella of anuran tadpole skin Dev Growth Differ. 2000 Dec; 42(6):571-80. . View in PubMed

Kdap, a novel gene associated with the stratification of the epithelium Gene. 2000 Oct 03; 256(1-2):19-27. . View in PubMed

Expression of genes of type I and type II collagen in the formation and development of the blastema of regenerating newt limb Dev Dyn. 1999 Sep; 216(1):59-71. . View in PubMed

Cell-type specific and thyroid hormone-dependent expression of genes of alpha1(I) and alpha2(I) collagen in intestine during amphibian metamorphosis Matrix Biol. 1999 Feb; 18(1):89-103. . View in PubMed

Cloning and characterization of the full length cDNA encoding alpha2 type I collagen of bullfrog Rana catesbeiana Gene. 1997 Jul 31; 194(2):283-9. . View in PubMed

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