Keck School Faculty

Lawrence R Menendez, MD
Lawrence R Menendez, MD
Professor of Clinical Orthopaedic Surgery
Orthopaedic Surgery
HC2 - 1520 San Pablo Street, #2000 Health Sciences Campus Los Angeles
Dr. Lawrence R Menendez is a Clinical Professor of Orthopaedic Surgery at the Keck Medical Center of USC where he specializes in the management of malignant and benign tumors of bone and soft tissue. He is one of only a handful of orthopaedic oncologists in Southern California who is experienced in performing complicated limb-sparing surgeries and other orthopaedic cancer techniques such as cryosurgery and radiofrequency ablation. Primary musculoskeletal cancers are rare. Dr. Menendez uses a coordinated, multidisciplinary approach to treatment with his colleagues from medical oncology, radiation oncology, nuclear medicine, radiology, surgical pathology, occupational and physical therapy and social services and pain management. Dr. Menendez is one of the most experienced orthopaedic oncologists in the nation and he has developed a special interest in the treatment of tumors of the pelvis and sacrum. A native of New Jersey, Dr. Menendez attended Middlebury College in Vermont and then received his medical degree from New York University School of Medicine where he was elected to the Alpha Omega Alpha Honor Society. He completed his surgical internship at Columbia Presbyterian Medical Center in New York City and his orthopaedic surgery residency at New York University Medical Center. After residency Dr. Menendez completed a fellowship in orthopaedic oncology at the University of Florida under the direction of Dr. William F Enneking. Dr. Menendez joined the faculty at USC in 1985 after his fellowship. Dr. Menendez has been involved in clinical research for over 27 years and is the author of numerous peer-reviewed research articles, book chapters and presentations. He has been invited to speak at universities both in the United States and abroad.

Pasadena Magazine: Top Doctor, 2017

Los Angeles Magazine: Super Doctor, 2016-2018

Castle Connolly: America's Top Doctors, 2016-2017

Castle Connolly: America's Top Doctors, 2016

Los Angeles Magazine: Super Doctor, 2016

Staging systems and nomograms in soft tissue sarcoma: outcome prediction by categorization or personalization? Chin Clin Oncol. 2019 Mar 06.. View in PubMed

Solid aneurysmal bone cyst of the humerus mimics metastasis or brown tumor Clin Imaging. 2018 Nov - Dec; 52:117-122. . View in PubMed

Giant cell tumor: rapid recurrence after cessation of long-term denosumab therapy Skeletal Radiol. 2015 Jul; 44(7):1027-31. . View in PubMed

Prognostic value of necrosis after neoadjuvant therapy for soft tissue sarcoma J Surg Oncol. 2015 Feb; 111(2):152-7. . View in PubMed

Early clinical and radiographic results of minimally invasive anterior approach hip arthroplasty Adv Orthop. 2014; 2014:954208. . View in PubMed

Clavicular eosinophilic granuloma causing adult shoulder pain Rare Tumors. 2013 Feb 11; 5(1):e8. . View in PubMed

Limb-sparing surgery for distal femoral and proximal tibial bone lesions: imaging findings with intraoperative correlation AJR Am J Roentgenol. 2013 Feb; 200(2):W193-203. . View in PubMed

Moving beyond response criteria: new measures of success in the treatment of sarcomas Curr Treat Options Oncol. 2012 Sep; 13(3):299-305. . View in PubMed

Endoprostheses last longer than intramedullary devices in proximal femur metastases Clin Orthop Relat Res. 2012 Mar; 470(3):684-91. . View in PubMed

A meta-analysis of osteosarcoma outcomes in the modern medical era Sarcoma. 2012; 2012:704872. . View in PubMed

A comparison of fine-needle aspiration, core biopsy, and surgical biopsy in the diagnosis of extremity soft tissue masses Clin Orthop Relat Res. 2010 Nov; 468(11):2992-3002. . View in PubMed

Modified Harrington reconstruction for advanced periacetabular metastatic disease J Surg Oncol. 2010 Feb 01; 101(2):170-4. . View in PubMed

Thermal ablation of osteoid osteoma: overview and step-by-step guide Radiographics. 2009 Nov; 29(7):2127-41. . View in PubMed

The linear cutting stapler may reduce surgical time and blood loss with muscle transection: a pilot study Clin Orthop Relat Res. 2009 Nov; 467(11):2859-64. . View in PubMed

Periacetabular reconstruction with a new endoprosthesis Clin Orthop Relat Res. 2009 Nov; 467(11):2831-7. . View in PubMed

En bloc shoulder resection with total shoulder prosthetic replacement: indications and imaging findings AJR Am J Roentgenol. 2008 Aug; 191(2):482-9. . View in PubMed

Reconstruction of type II pelvic resection with a new peri-acetabular reconstruction endoprosthesis J Bone Joint Surg Br. 2008 Mar; 90(3):371-6. . View in PubMed

Unusual locations for metastatic malignancy of the hand: a report of three cases J Surg Orthop Adv. 2008; 17(4):267-70. . View in PubMed

F-18 FDG PET and PET/CT evaluation of response to chemotherapy in bone and soft tissue sarcomas Clin Nucl Med. 2008 Jan; 33(1):8-13. . View in PubMed

Cryoablation and resection influences patient survival for soft tissue sarcomas: impact on survivorship and local recurrence Clin Orthop Relat Res. 2007 Jun; 459:174-81. . View in PubMed

Tumor necrosis has no prognostic value in neoadjuvant chemotherapy for soft tissue sarcoma Clin Orthop Relat Res. 2007 Feb; 455:219-24. . View in PubMed

Intercalary endoprosthetic reconstruction for diaphyseal bone tumours J Bone Joint Surg Br. 2006 Nov; 88(11):1487-91. . View in PubMed

Influence of cryosurgery on treatment outcome of low-grade chondrosarcoma Clin Orthop Relat Res. 2006 Oct; 451:201-7. . View in PubMed

18F-FDG PET and PET/CT for detection of pulmonary metastases from musculoskeletal sarcomas Nucl Med Commun. 2006 Oct; 27(10):795-802. . View in PubMed

Endoprosthetic reconstruction for neoplasms of the proximal femur Clin Orthop Relat Res. 2006 Sep; 450:46-51. . View in PubMed

Survivorship and clinical outcome of modular endoprosthetic reconstruction for neoplastic disease of the lower limb J Bone Joint Surg Br. 2006 Jun; 88(6):790-5. . View in PubMed

Concomitant vascular procedures for malignancies with vascular invasion Arch Surg. 2002 Aug; 137(8):901-6; discussion 906-7. . View in PubMed

The use of calcium sulfate in the treatment of benign bone lesionsA preliminary report. J Bone Joint Surg Am. 2001 Mar; 83(3):355-8. . View in PubMed

Cryosurgical ablation of soft tissue sarcomas: a phase I trial of feasibility and safety Cancer. 1999 Jul 01; 86(1):50-7. . View in PubMed

MRI evaluation of post-operative seromas in extremity soft tissue sarcomas Skeletal Radiol. 1999 May; 28(5):279-82. . View in PubMed

Methotrexate eluted from bone cement: effect on giant cell tumor of bone in vitro Clin Orthop Relat Res. 1996 Jul; (328):294-303. . View in PubMed

Preoperative CT localization and marking of osteoid osteoma: description of a new technique J Comput Assist Tomogr. 1996 Jul-Aug; 20(4):526-9. . View in PubMed

Kasabach-Merritt syndrome complicating treatment of a closed femoral fracture Clin Orthop Relat Res. 1995 Jul; (316):185-8. . View in PubMed

Case report 797: "Dedifferentiated" lipoma-like liposarcoma of soft tissue with focal transformation to high-grade "sclerosing" osteosarcoma Skeletal Radiol. 1993 Nov; 22(8):604-8. . View in PubMed

Serial thallium-201 scintigraphy in osteosarcomaCorrelation with tumor necrosis after preoperative chemotherapy. Clin Orthop Relat Res. 1993 Aug; (293):302-6. . View in PubMed

Reconstructive considerations for limb salvage surgery Orthop Clin North Am. 1993 Jul; 24(3):511-21. . View in PubMed

Thallium-201 scanning for the evaluation of osteosarcoma and soft-tissue sarcomaA study of the evaluation and predictability of the histological response to chemotherapy. J Bone Joint Surg Am. 1993 Apr; 75(4):526-31. . View in PubMed

Bone remodelling in the presence of chondrosarcoma: histomorphometry Acta Anat (Basel). 1993; 148(1):1-7. . View in PubMed

Synovial sarcomaA clinicopathologic study. Orthop Rev. 1992 Apr; 21(4):465-71. . View in PubMed

Limb salvage surgery for bone and soft tissue sarcomaA phase II pathologic study of preoperative intraarterial cisplatin. Cancer. 1991 Aug 15; 68(4):738-43. . View in PubMed

Malignant tumors of the upper extremity in children Orthop Rev. 1990 May; 19(5):411-7. . View in PubMed

Neurofibroma in a patient with von Recklinghausen's disease seen as a malignant schwannomaA case report. Clin Orthop Relat Res. 1990 May; (254):298-302. . View in PubMed

Fat embolism syndrome complicating intraarterial chemotherapy with cis-platinum Clin Orthop Relat Res. 1990 May; (254):294-7. . View in PubMed

Diaphyseal intraosseous ganglion Clin Orthop Relat Res. 1988 Feb; 227:310-2. . View in PubMed

Limited posterolateral surgical approach to the knee for excision of osteoid osteoma Clin Orthop Relat Res. 1987 Oct; (223):237-46. . View in PubMed

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