Keck School Faculty

Ling Shao, MD, PhD
Ling Shao, MD, PhD
Assistant Professor of Medicine
Medicine
HMR 2011 Zonal Avenue Off Campus Los Angeles
Dr. Shao's major areas of research interest are inflammatory bowel disease, intestinal epithelial cells, inflammation and immunology. His major area of research interest is the role that intestinal epithelial cells play in the pathogenesis of inflammatory bowel disease. Specifically, he studies how genetics, the immune system, and the microbiome may influence epithelial wound healing, but also predisposes patients to developing colon cancer. He also studies the underlying immune mechanisms of why patients develop resistance to certain medications used to treat inflammatory bowel disease.

Dr. Shao earned his medical degree from The Mount Sinai School of Medicine. He then performed his residency at University of California, San Francisco, and then stayed on to complete a Gastroenterology Fellowship.

Division of Gastroenterology and Liver Diseases, USC: GI Fellows Teaching Award, 2015

Inflammatory Bowel Disease Working Group: The Inflammatory Bowel Disease Working Group Fellowship Award, 2012

The Arnold P. Gold Foundation: The Arnold P. Gold Humanism Honor Society, 2006

The Mount Sinai School of Medicine: The Mount Sinai Student Council Teamwork Award, 2006

The Jeffrey Modell Foundation: The Jeffrey Modell Foundation Award, 2005

The Mount Sinai School of Medicine: The Mount Sinai Graduate School Service Award, 2003

A20 and ABIN-1 synergistically preserve intestinal epithelial cell survival J Exp Med. 2018 Jun 21. . View in PubMed

A20 regulates canonical wnt-signaling through an interaction with RIPK4 PLoS One. 2018; 13(5):e0195893. . View in PubMed

Isolated Ileocolonic Histoplasmosis in an HIV-Negative Patient Dig Dis Sci. 2017 Aug; 62(8):2201-2202. . View in PubMed

Planar microdevices for enhanced in vivo retention and oral bioavailability of poorly permeable drugs Adv Healthc Mater. 2014 Oct; 3(10):1648-54. . View in PubMed

A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis PLoS One. 2013; 8(5):e62223. . View in PubMed

Expression of nonclassical class I molecules by intestinal epithelial cells Inflamm Bowel Dis. 2007 Mar; 13(3):298-307. . View in PubMed

Immunomodulatory roles of the carcinoembryonic antigen family of glycoproteins Ann N Y Acad Sci. 2006 Aug; 1072:194-209. . View in PubMed

Further evidence that ribavirin interacts with eIF4E RNA. 2005 Dec; 11(12):1762-6. . View in PubMed

Non-classical MHC class I molecules on intestinal epithelial cells: mediators of mucosal crosstalk Immunol Rev. 2005 Aug; 206:160-76. . View in PubMed

Activation of CD8+ regulatory T cells by human placental trophoblasts J Immunol. 2005 Jun 15; 174(12):7539-47. . View in PubMed

Defects in CD8+ regulatory T cells in the lamina propria of patients with inflammatory bowel disease J Immunol. 2005 May 01; 174(9):5814-22. . View in PubMed

Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap Proc Natl Acad Sci U S A. 2004 Dec 28; 101(52):18105-10. . View in PubMed

Activation of a unique population of CD8(+) T cells by intestinal epithelial cells Ann N Y Acad Sci. 2004 Dec; 1029:22-35. . View in PubMed

Treatment of disease through oral tolerance Discov Med. 2004 Oct; 4(23):338-43. . View in PubMed

The use of oral tolerance in the therapy of chronic inflammatory/autoimmune diseases J Pediatr Gastroenterol Nutr. 2004 Jun; 39 Suppl 3:S746-7. . View in PubMed

Therapeutic potential of oral tolerance Nat Rev Immunol. 2004 Jun; 4(6):407-19. . View in PubMed

The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells Gastroenterology. 2004 May; 126(5):1347-57. . View in PubMed

Neurologic consequences of HIV infection in the era of HAART AIDS Patient Care STDS. 2003 Oct; 17(10):509-18. . View in PubMed

Intestinal heat shock protein 110 regulates expression of CD1d on intestinal epithelial cells J Clin Invest. 2003 Sep; 112(5):745-54. . View in PubMed

Impaired regulation of HLA-DR expression in human immunodeficiency virus-infected monocytes Clin Diagn Lab Immunol. 2002 Jul; 9(4):739-46. . View in PubMed

The role of epithelial cells in immune regulation in the gut Semin Immunol. 2001 Jun; 13(3):163-76. . View in PubMed

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