Keck School Faculty

Lori Walker, MD
Lori Walker, MD
Clinical Assistant Professor of Family Medicine (Practitioner)
Family Medicine
ESH 244 University Park Campus Los Angeles
Lori Walker, MD received her medical degree from the Charles R. Drew University of California, Los Angeles. She served her residency in Internal Medicine at the Martin Luther King Hospital and is board-certified in Internal Medicine. She is a member of the American College of Physicians.

Increased myocyte calcium sensitivity in end-stage pediatric dilated cardiomyopathy Am J Physiol Heart Circ Physiol. 2019 Dec 01; 317(6):H1221-H1230. . View in PubMed

Intense Light-Mediated Circadian Cardioprotection via Transcriptional Reprogramming of the EndotheliumCell Rep. 2019 Aug 06; 28(6):1471-1484. e11. . View in PubMed

The right ventricular fibroblast secretome drives cardiomyocyte dedifferentiation PLoS One. 2019; 14(8):e0220573. . View in PubMed

LAMP-2B regulates human cardiomyocyte function by mediating autophagosome-lysosome fusion Proc Natl Acad Sci U S A. 2019 01 08; 116(2):556-565. . View in PubMed

Glucagon-like peptide-1 receptor antagonism impairs basal exercise capacity and vascular adaptation to aerobic exercise training in rats Physiol Rep. 2018 07; 6(13):e13754. . View in PubMed

Exercise and Pharmacology as Medicine for Cardiovascular Diseases: From Bench to Bedside and Back Exerc Sport Sci Rev. 2018 01; 46(1):2-3. . View in PubMed

Marijuana use and short-term outcomes in patients hospitalized for acute myocardial infarction PLoS One. 2018; 13(7):e0199705. . View in PubMed

Interleukin-19 is cardioprotective in dominant negative cyclic adenosine monophosphate response-element binding protein-mediated heart failure in a sex-specific manner World J Cardiol. 2017 Aug 26; 9(8):673-684. . View in PubMed

Genetic ablation of interleukin-18 does not attenuate hypobaric hypoxia-induced right ventricular hypertrophy Am J Physiol Lung Cell Mol Physiol. 2016 Mar 15; 310(6):L542-50. . View in PubMed

Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth muscle differentiation Nat Commun. 2016 Mar 04; 7:10830. . View in PubMed

Differential Mitochondrial Adaptation in Primary Vascular Smooth Muscle Cells from a Diabetic Rat Model Oxid Med Cell Longev. 2016; 2016:8524267. . View in PubMed

High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling Nat Commun. 2015 Sep 10; 6:8243. . View in PubMed

Differential Tissue-Specific Function of Adora2b in Cardioprotection J Immunol. 2015 Aug 15; 195(4):1732-43. . View in PubMed

Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunction Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15; 308(2):L158-67. . View in PubMed

Characterization and validation of new tools for measuring site-specific cardiac troponin I phosphorylation J Immunol Methods. 2014 Jan 31; 403(1-2):66-71. . View in PubMed

Contractile protein phosphorylation predicts human heart disease phenotypes Am J Physiol Heart Circ Physiol. 2013 Jun 15; 304(12):H1644-50. . View in PubMed

The right ventricle: biologic insights and response to disease: updated Curr Cardiol Rev. 2013 Feb 01; 9(1):73-81. . View in PubMed

Serendipitous discovery of a novel protein signaling mechanism in heart failure Biochem Biophys Res Commun. 2012 May 11; 421(3):431-5. . View in PubMed

Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia Nat Med. 2012 Apr 15; 18(5):774-82. . View in PubMed

Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism Circ Res. 2012 Mar 02; 110(5):739-48. . View in PubMed

Temporal expression of miRNAs and mRNAs in a mouse model of myocardial infarction Physiol Genomics. 2011 Oct 06; 43(19):1087-95. . View in PubMed

Biochemical and myofilament responses of the right ventricle to severe pulmonary hypertension Am J Physiol Heart Circ Physiol. 2011 Sep; 301(3):H832-40. . View in PubMed

Protein kinase A changes calcium sensitivity but not crossbridge kinetics in human cardiac myofibrils Am J Physiol Heart Circ Physiol. 2011 Jul; 301(1):H138-46. . View in PubMed

Incomplete recovery of myocyte contractile function despite improvement of myocardial architecture with left ventricular assist device support Circ Heart Fail. 2011 Jul; 4(4):425-32. . View in PubMed

Tissue procurement strategies affect the protein biochemistry of human heart samples J Muscle Res Cell Motil. 2011 Mar; 31(5-6):309-14. . View in PubMed

Stage-specific changes in myofilament protein phosphorylation following myocardial infarction in mice J Mol Cell Cardiol. 2010 Jun; 48(6):1180-6. . View in PubMed

Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation J Biol Chem. 2009 Feb 20; 284(8):5097-106. . View in PubMed

The right ventricle: biologic insights and response to disease Curr Cardiol Rev. 2009 Jan; 5(1):22-8. . View in PubMed

Partial replacement of cardiac troponin I with a non-phosphorylatable mutant at serines 43/45 attenuates the contractile dysfunction associated with PKCepsilon phosphorylation J Mol Cell Cardiol. 2006 Apr; 40(4):465-73. . View in PubMed

Depressed cardiac myofilament function in human diabetes mellitus Am J Physiol Heart Circ Physiol. 2005 Dec; 289(6):H2478-83. . View in PubMed

Protein kinase Cepsilon overexpression alters myofilament properties and composition during the progression of heart failure Circ Res. 2004 Aug 20; 95(4):424-32. . View in PubMed

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