Keck School Faculty

Lynda Diane Roman, MD
Lynda Diane Roman, MD
Associate Professor of Obstetrics & Gynecology;Division Chief, Gynecologic Oncology;Director, Gynecology Oncology Fellowship
Obstetrics & Gynecology
IRD 520 2020 Zonal Ave Off Campus Los Angeles
Dr. Roman completed her fellowship in gynecologic oncology at the MD Anderson Cancer Center in Houston, Texas in 1991. Presently, she serves as Director of the Division of Gynecologic Oncology at the University of Southern California, as well as the Director of Research and the Fellowship Program Director. Also, Dr. Roman is the co-director of the Lynne Cohen Preventive Cancer Care Clinic at the USC/Norris Cancer Center. she has recently been appointed to the governing council of the Society of Gynecologic Oncologists.

Characteristics and outcomes of reproductive-aged women with early-stage cervical cancer: trachelectomy vs hysterectomyAm J Obstet Gynecol. 2018 Nov; 219(5):461. e1-461. e18. . View in PubMed

Risk of metachronous ovarian cancer after ovarian conservation in young women with stage I cervical cancerAm J Obstet Gynecol. 2017 11; 217(5):580. e1-580. e10. . View in PubMed

Cervical conization of adenocarcinoma in situ: a predicting model of residual diseaseAm J Obstet Gynecol. 2014 Apr; 210(4):366. e1-366. e5. . View in PubMed

Association of statins, aspirin, and venous thromboembolism in women with endometrial cancer Gynecol Oncol. 2019 Jan 04. . View in PubMed

Survival outcome prediction in cervical cancer: Cox models versus deep-learning model Am J Obstet Gynecol. 2018 Dec 21. . View in PubMed

Association of tumor differentiation grade and survival of women with squamous cell carcinoma of the uterine cervix J Gynecol Oncol. 2018 Nov; 29(6):e91. . View in PubMed

Predictive Value of FDG PET/CT to Detect Lymph Node Metastases in Cervical Cancer Clin Nucl Med. 2018 Nov; 43(11):793-801. . View in PubMed

Trachelectomy for stage IB1 cervical cancer with tumor size >2 cm: trends and characteristics in the United States J Gynecol Oncol. 2018 Nov; 29(6):e85. . View in PubMed

Clinical utility of CA-125 in the management of uterine carcinosarcoma J Gynecol Oncol. 2018 Nov; 29(6):e88. . View in PubMed

Proposal for a Risk-Based Categorization of Uterine Carcinosarcoma Ann Surg Oncol. 2018 Nov; 25(12):3676-3684. . View in PubMed

Validity and prognostic significance of sperm protein 17 as a tumor biomarker for epithelial ovarian cancer: a retrospective study BMC Cancer. 2018 Oct 11; 18(1):970. . View in PubMed

Tumor-specific outcome of metachronous uterine malignancy after pelvic irradiation for cervical cancer Gynecol Oncol. 2018 Sep 06. . View in PubMed

Significance of Lymphovascular Space Invasion by the Sarcomatous Component in Uterine Carcinosarcoma Ann Surg Oncol. 2018 Sep; 25(9):2756-2766. . View in PubMed

Characterizing sarcoma dominance pattern in uterine carcinosarcoma: Homologous versus heterologous element Surg Oncol. 2018 Sep; 27(3):433-440. . View in PubMed

Efficacy of Modified Dose-dense Paclitaxel in Recurrent Cervical Cancer Am J Clin Oncol. 2018 Sep; 41(9):851-860. . View in PubMed

Adequate pelvic lymphadenectomy and survival of women with early-stage epithelial ovarian cancer J Gynecol Oncol. 2018 Sep; 29(5):e69. . View in PubMed

Predictive Value of FDG PET/CT to Detect Lymph Node Metastases in Cervical Cancer Clin Nucl Med. 2018 Aug 27. . View in PubMed

Characteristics and outcomes of reproductive-aged women with early-stage cervical cancer: trachelectomy versus hysterectomy Am J Obstet Gynecol. 2018 Aug 20. . View in PubMed

Proposal for a Risk-Based Categorization of Uterine Carcinosarcoma Ann Surg Oncol. 2018 Aug 13. . View in PubMed

Nivolumab use for BRCA gene mutation carriers with recurrent epithelial ovarian cancer: A case series Gynecol Oncol Rep. 2018 Aug; 25:98-101. . View in PubMed

Incidences and risk factors of metachronous vulvar, vaginal, and anal cancers after cervical cancer diagnosis Gynecol Oncol. 2018 Jul 24. . View in PubMed

Significance of Lymphovascular Space Invasion by the Sarcomatous Component in Uterine Carcinosarcoma Ann Surg Oncol. 2018 Jul 03. . View in PubMed

Trends and outcomes of women with synchronous endometrial and ovarian cancer Oncotarget. 2018 Jun 19; 9(47):28757-28771. . View in PubMed

A Phase I Clinical Trial of Guadecitabine and Carboplatin in Platinum-Resistant, Recurrent Ovarian Cancer: Clinical, Pharmacokinetic, and Pharmacodynamic Analyses Clin Cancer Res. 2018 May 15; 24(10):2285-2293. . View in PubMed

Adequate pelvic lymphadenectomy and survival of women with early-stage epithelial ovarian cancer J Gynecol Oncol. 2018 May 04. . View in PubMed

Significance of abnormal peritoneal cytology on survival of women with stage I-II endometrioid endometrial cancer Gynecol Oncol. 2018 Mar 12. . View in PubMed

Trends in single women with malignancy of the uterine cervix in United States J Gynecol Oncol. 2018 Mar; 29(2):e24. . View in PubMed

Trends of uterine carcinosarcoma in the United States J Gynecol Oncol. 2018 Mar; 29(2):e22. . View in PubMed

Fully sialylated alpha-chain of complement 4-binding protein (A2160): a novel prognostic marker for epithelial ovarian carcinoma Arch Gynecol Obstet. 2018 Mar; 297(3):749-756. . View in PubMed

Survival outcome of women with stage IV uterine carcinosarcoma who received neoadjuvant chemotherapy followed by surgery J Surg Oncol. 2018 Mar; 117(3):488-496. . View in PubMed

Reply Am J Obstet Gynecol. 2018 Feb; 218(2):264. . View in PubMed

Impact of lympho-vascular space invasion on tumor characteristics and survival outcome of women with low-grade serous ovarian carcinoma J Surg Oncol. 2018 Feb; 117(2):236-244. . View in PubMed

Significance of venous thromboembolism in women with uterine carcinosarcoma Gynecol Oncol. 2018 Feb; 148(2):267-274. . View in PubMed

Tumor-specific outcome of metachronous uterine malignancy after pelvic irradiation for cervical cancer Gynecol Oncol. 2018 11; 151(2):250-256. . View in PubMed

Incidences and risk factors of metachronous vulvar, vaginal, and anal cancers after cervical cancer diagnosis Gynecol Oncol. 2018 09; 150(3):501-508. . View in PubMed

Significance of abnormal peritoneal cytology on survival of women with stage I-II endometrioid endometrial cancer Gynecol Oncol. 2018 05; 149(2):301-309. . View in PubMed

Fully sialylated alpha-chain of complement 4-binding protein (A2160): a novel prognostic marker for epithelial ovarian carcinoma Arch Gynecol Obstet. 2018 03; 297(3):749-756. . View in PubMed

Trends of uterine carcinosarcoma in the United States J Gynecol Oncol. 2018 03; 29(2):e22. . View in PubMed

Trends in single women with malignancy of the uterine cervix in United States J Gynecol Oncol. 2018 03; 29(2):e24. . View in PubMed

Significance of venous thromboembolism in women with uterine carcinosarcoma Gynecol Oncol. 2018 02; 148(2):267-274. . View in PubMed

Reply Am J Obstet Gynecol. 2018 02; 218(2):264. . View in PubMed

Survival outcome of women with stage IV uterine carcinosarcoma who received neoadjuvant chemotherapy followed by surgery J Surg Oncol. 2017 Oct 16. . View in PubMed

Patient compliance for postoperative radiotherapy and survival outcome of women with stage I endometrioid endometrial cancer J Surg Oncol. 2017 Sep; 116(4):482-491. . View in PubMed

Risk of Subsequent Ovarian Cancer After Ovarian Conservation in Young Women With Stage I Endometrioid Endometrial Cancer Obstet Gynecol. 2017 Aug; 130(2):403-410. . View in PubMed

Efficacy of Modified Dose-dense Paclitaxel in Recurrent Cervical Cancer Am J Clin Oncol. 2017 Jul 31. . View in PubMed

Endometrial cancer arising in adenomyosis versus endometrial cancer coexisting with adenomyosis: are these two different entities? Arch Gynecol Obstet. 2017 Jun; 295(6):1459-1468.. View in PubMed

Prognosis of women with apparent stage I endometrial cancer who had supracervical hysterectomy Gynecol Oncol. 2017 Apr; 145(1):41-49. . View in PubMed

Tumor characteristics and survival outcomes of women with tamoxifen-related uterine carcinosarcoma Gynecol Oncol. 2017 Feb; 144(2):329-335. . View in PubMed

Prognosis of women with stage I endometrioid endometrial cancer and synchronous stage I endometrioid ovarian cancer Gynecol Oncol. 2017 12; 147(3):558-564. . View in PubMed

A pilot study in using deep learning to predict limited life expectancy in women with recurrent cervical cancer Am J Obstet Gynecol. 2017 12; 217(6):703-705. . View in PubMed

Salvage chemotherapy with taxane and platinum for women with recurrent uterine carcinosarcoma Gynecol Oncol. 2017 12; 147(3):565-571. . View in PubMed

Single Marital Status and Infectious Mortality in Women With Cervical Cancer in the United States Int J Gynecol Cancer. 2017 10; 27(8):1737-1746. . View in PubMed

Risk of Subsequent Ovarian Cancer After Ovarian Conservation in Young Women With Stage I Endometrioid Endometrial Cancer Obstet Gynecol. 2017 08; 130(2):403-410. . View in PubMed

Impact of adjuvant therapy on recurrence patterns in stage I uterine carcinosarcoma Gynecol Oncol. 2017 04; 145(1):78-87. . View in PubMed

Role of hysterectomy and lymphadenectomy in the management of early-stage borderline ovarian tumors Gynecol Oncol. 2017 03; 144(3):496-502. . View in PubMed

Extent of pelvic lymphadenectomy and use of adjuvant vaginal brachytherapy for early-stage endometrial cancer Gynecol Oncol. 2017 03; 144(3):515-523. . View in PubMed

Ovarian Conservation and Overall Survival in Young Women With Early-Stage Cervical Cancer Obstet Gynecol. 2017 01; 129(1):139-151. . View in PubMed

A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer Int J Cancer. 2016 Dec 15; 139(12):2646-2654. . View in PubMed

Endoplasmic reticulum stress in complex atypical hyperplasia as a possible predictor of occult carcinoma and progestin response Gynecol Oncol. 2016 Dec; 143(3):650-654. . View in PubMed

Association of Low-Dose Aspirin and Survival of Women With Endometrial Cancer Obstet Gynecol. 2016 Jul; 128(1):127-37. . View in PubMed

Tumor Characteristics and Survival Outcome of Endometrial Cancer Arising in Adenomyosis: An Exploratory Analysis Ann Surg Oncol. 2016 Mar; 23(3):959-67. . View in PubMed

Predictive Factor of Conversion to Laparotomy in Minimally Invasive Surgical Staging for Endometrial Cancer Int J Gynecol Cancer. 2016 Feb; 26(2):290-300. . View in PubMed

Surgical menopause and increased risk of nonalcoholic fatty liver disease in endometrial cancer Menopause. 2016 Feb; 23(2):189-96. . View in PubMed

Timing of Intrauterine Manipulator Insertion During Minimally Invasive Surgical Staging and Results of Pelvic Cytology in Endometrial Cancer J Minim Invasive Gynecol. 2016 Feb 01; 23(2):234-41. . View in PubMed

Ovarian Conservation and Overall Survival in Young Women With Early-Stage Low-Grade Endometrial Cancer Obstet Gynecol. 2016 10; 128(4):761-70. . View in PubMed

Significance of venous thromboembolism in women with cervical cancer Gynecol Oncol. 2016 09; 142(3):405-12. . View in PubMed

Contributing factors for menopausal symptoms after surgical staging for endometrial cancer Menopause. 2016 05; 23(5):535-43. . View in PubMed

Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk Obstet Gynecol. 2016 05; 127(5):828-36. . View in PubMed

Langerhans cells from women with cervical precancerous lesions become functionally responsive against human papillomavirus after activation with stabilized Poly-I:C Clin Immunol. 2015 Dec; 161(2):197-208. . View in PubMed

Prediction of concurrent endometrial carcinoma in women with endometrial hyperplasia Gynecol Oncol. 2015 Nov; 139(2):261-7. . View in PubMed

Impact of depth and extent of lymphovascular space invasion on lymph node metastasis and recurrence patterns in endometrial cancer J Surg Oncol. 2015 Nov; 112(6):669-76. . View in PubMed

Effects of imiquimod on vulvar Paget's disease: a systematic review of literature Gynecol Oncol. 2015 Oct; 139(1):165-71. . View in PubMed

Venous thromboembolism, interleukin-6 and survival outcomes in patients with advanced ovarian clear cell carcinoma Eur J Cancer. 2015 Sep; 51(14):1978-88. . View in PubMed

Characteristics of ovarian tumors of low malignant potential in BRCA mutation carriers: A case series Gynecol Oncol Rep. 2015 Aug; 13:36-9. . View in PubMed

Significance of monocyte counts on tumor characteristics and survival outcome of women with endometrial cancer Gynecol Oncol. 2015 Aug; 138(2):332-8. . View in PubMed

In reply Obstet Gynecol. 2015 Jun; 125(6):1498. . View in PubMed

Population distribution of lifetime risk of ovarian cancer in the United States Cancer Epidemiol Biomarkers Prev. 2015 Apr; 24(4):671-676. . View in PubMed

Escalation of oncologic services at the end of life among patients with gynecologic cancer at an urban, public hospital J Oncol Pract. 2015 Mar; 11(2):e163-9. . View in PubMed

Time interval between endometrial biopsy and surgical staging for type I endometrial cancer: association between tumor characteristics and survival outcome Obstet Gynecol. 2015 Feb; 125(2):424-33. . View in PubMed

Survival outcome of stage I ovarian clear cell carcinoma with lympho-vascular space invasion Gynecol Oncol. 2015 Feb; 136(2):198-204. . View in PubMed

Molecular Analysis of Mixed Endometrioid and Serous Adenocarcinoma of the Endometrium PLoS One. 2015; 10(7):e0130909. . View in PubMed

Significance of adenomyosis on tumor progression and survival outcome of endometrial cancer Ann Surg Oncol. 2014 Dec; 21(13):4246-55. . View in PubMed

Phase I clinical trial of temsirolimus and vinorelbine in advanced solid tumors Cancer Chemother Pharmacol. 2014 Dec; 74(6):1227-34. . View in PubMed

Estrogen receptor expression and increased risk of lymphovascular space invasion in high-grade serous ovarian carcinoma Gynecol Oncol. 2014 Jun; 133(3):473-9. . View in PubMed

Effect of lymphovascular space invasion on survival of stage I epithelial ovarian cancer Obstet Gynecol. 2014 May; 123(5):957-65. . View in PubMed

A phase II trial of oxaliplatin, docetaxel, and bevacizumab as first-line therapy of advanced cancer of the ovary, peritoneum, and fallopian tube Gynecol Oncol. 2014 Mar; 132(3):517-25. . View in PubMed

Abdominal aortic resection and Y-graft placement to achieve complete cytoreduction in stage IIIc ovarian carcinoma Obstet Gynecol. 2014 Feb; 123(2 Pt 2 Suppl 2):486-8. . View in PubMed

Endometrial echo complex thickness in postmenopausal endometrial cancer Gynecol Oncol. 2013 Oct; 131(1):109-12. . View in PubMed

Reporting of quality measures in gynecologic oncology programs at Prospective Payment System (PPS)-Exempt Cancer Hospitals: an early glimpse into a challenging initiative Gynecol Oncol. 2013 Sep; 130(3):403-6. . View in PubMed

Predictive model of venous thromboembolism in endometrial cancer Gynecol Oncol. 2013 Mar; 128(3):544-51. . View in PubMed

Successful extraction of cardiac-extending intravenous leiomyomatosis through gonadal veinFertil Steril. 2012 Nov; 98(5):1341-5. e1. . View in PubMed

Significance of lymphovascular space invasion in epithelial ovarian cancer Cancer Med. 2012 Oct; 1(2):156-64. . View in PubMed

Phase II study of gemcitabine and docetaxel in recurrent platinum resistant ovarian cancer Cancer Invest. 2012 May; 30(4):295-9. . View in PubMed

Significance of perioperative infection in survival of patients with ovarian cancer Int J Gynecol Cancer. 2012 Feb; 22(2):245-53. . View in PubMed

Long-term pegylated liposomal doxorubicin use and oromaxillary squamous cell carcinoma in endometrial cancer Oncologist. 2012; 17(12):1598-9. . View in PubMed

Genome-scale screen for DNA methylation-based detection markers for ovarian cancer PLoS One. 2011; 6(12):e28141. . View in PubMed

Overcoming platinum resistance in ovarian carcinoma Expert Opin Investig Drugs. 2010 Nov; 19(11):1339-54. . View in PubMed

Analysis of outcomes of microinvasive adenocarcinoma of the uterine cervix by treatment type Obstet Gynecol. 2010 Nov; 116(5):1150-7. . View in PubMed

Phase II trial of bevacizumab in the treatment of persistent or recurrent squamous cell carcinoma of the cervix: a gynecologic oncology group study J Clin Oncol. 2009 Mar 01; 27(7):1069-74. . View in PubMed

Polymorphisms and clinical outcome in recurrent ovarian cancer treated with cyclophosphamide and bevacizumab Clin Cancer Res. 2008 Nov 15; 14(22):7554-63. . View in PubMed

Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago, and Princess Margaret Hospital phase II consortia J Clin Oncol. 2008 Jan 01; 26(1):76-82. . View in PubMed

Phase II clinical trial of docetaxel in refractory squamous cell carcinoma of the cervix: a Gynecologic Oncology Group Study Am J Clin Oncol. 2007 Aug; 30(4):428-31. . View in PubMed

Therapeutic vaccination for HPV induced cervical cancers Dis Markers. 2007; 23(4):337-52. . View in PubMed

Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: potential predictive relationship with tumor HER2 activation status J Clin Oncol. 2006 Sep 10; 24(26):4324-32. . View in PubMed

Feasibility of laparoscopic extraperitoneal surgical staging for locally advanced cervical carcinoma in a gynecologic oncology fellowship training program J Minim Invasive Gynecol. 2006 Sep-Oct; 13(5):391-7. . View in PubMed

Influence of quantity of lymph vascular space invasion on time to recurrence in women with early-stage squamous cancer of the cervix Gynecol Oncol. 2006 Feb; 100(2):288-93. . View in PubMed

Pregnancy after radical vaginal trachelectomy: maybe not such a risky undertaking after all Gynecol Oncol. 2005 Jul; 98(1):1-2. . View in PubMed

Optimal cytoreduction after combined resection and radiofrequency ablation of hepatic metastases from recurrent malignant ovarian tumors Gynecol Oncol. 2005 Apr; 97(1):266-70. . View in PubMed

Phase I clinical trial of topotecan and pegylated liposomal doxorubicin Cancer Invest. 2005; 23(8):665-70. . View in PubMed

Extraperitoneal laparoscopic lymph node staging: the University of Southern California experience Gynecol Oncol. 2004 Oct; 95(1):189-92. . View in PubMed

Phase II study of gemcitabine and weekly paclitaxel in recurrent platinum-resistant ovarian cancer Gynecol Oncol. 2004 May; 93(2):493-8. . View in PubMed

Detection of residual subclinical ovarian carcinoma after completion of adjuvant chemotherapy Clin Cancer Res. 2004 Apr 15; 10(8):2681-6. . View in PubMed

Radical vaginal trachelectomy and pelvic lymphadenectomy for preservation of fertility in early cervical carcinoma Gynecol Oncol. 2003 Mar; 88(3):419-23. . View in PubMed

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