Keck School Faculty

Lynda Diane Roman, MD
Lynda Diane Roman, MD
Associate Professor of Obstetrics & Gynecology;Division Chief, Gynecologic Oncology;Director, Gynecology Oncology Fellowship
Obstetrics & Gynecology
IRD 520 2020 Zonal Ave Off Campus Los Angeles
Dr. Roman completed her fellowship in gynecologic oncology at the MD Anderson Cancer Center in Houston, Texas in 1991. Presently, she serves as Director of the Division of Gynecologic Oncology at the University of Southern California, as well as the Director of Research and the Fellowship Program Director. Also, Dr. Roman is the co-director of the Lynne Cohen Preventive Cancer Care Clinic at the USC/Norris Cancer Center. she has recently been appointed to the governing council of the Society of Gynecologic Oncologists.

Cervical conization of adenocarcinoma in situ: a predicting model of residual diseaseAm J Obstet Gynecol. 2014 Apr; 210(4):366. e1-366. e5. . View in PubMed

Characteristics and outcomes of reproductive-aged women with early-stage cervical cancer: trachelectomy vs hysterectomyAm J Obstet Gynecol. 2018 11; 219(5):461. e1-461. e18. . View in PubMed

Hospital surgical volume and perioperative mortality of pelvic exenteration for gynecologic malignancies J Surg Oncol. 2019 Nov 19. . View in PubMed

Expression of the luteinizing hormone receptor (LHR) in ovarian cancer BMC Cancer. 2019 Nov 15; 19(1):1114. . View in PubMed

Non-prescription cannabis use for symptom management amongst women with gynecologic malignancies Gynecol Oncol Rep. 2019 Nov; 30:100497. . View in PubMed

Dysregulation of Placental Functions and Immune Pathways in Complete Hydatidiform Moles Int J Mol Sci. 2019 Oct 10; 20(20). . View in PubMed

Efficacy of pegylated liposomal doxorubicin maintenance therapy in platinum-sensitive recurrent epithelial ovarian cancer: a retrospective study Arch Gynecol Obstet. 2019 Jun; 299(6):1641-1649. . View in PubMed

Decreasing Trends of Secondary Primary Colorectal Cancer among Women with Uterine Cancer: A Population-Based Analysis J Clin Med. 2019 May 20; 8(5). . View in PubMed

Effectiveness of postoperative chemotherapy for stage IC mucinous ovarian cancer Gynecol Oncol. 2019 09; 154(3):505-515. . View in PubMed

Decreasing secondary primary uterine cancer after breast cancer: A population-based analysis Gynecol Oncol. 2019 07; 154(1):169-176. . View in PubMed

Patterns of utilization and outcome of ovarian conservation for young women with minimal-risk endometrial cancer Gynecol Oncol. 2019 07; 154(1):45-52. . View in PubMed

Mucinous borderline ovarian tumor versus invasive well-differentiated mucinous ovarian cancer: Difference in characteristics and outcomes Gynecol Oncol. 2019 05; 153(2):230-237. . View in PubMed

Performance and outcome of pelvic exenteration for gynecologic malignancies: A population-based study Gynecol Oncol. 2019 05; 153(2):368-375. . View in PubMed

Association of statins, aspirin, and venous thromboembolism in women with endometrial cancer Gynecol Oncol. 2019 03; 152(3):605-611. . View in PubMed

Association of tumor differentiation grade and survival of women with squamous cell carcinoma of the uterine cervix J Gynecol Oncol. 2018 Nov; 29(6):e91. . View in PubMed

Adequate pelvic lymphadenectomy and survival of women with early-stage epithelial ovarian cancer J Gynecol Oncol. 2018 Sep; 29(5):e69. . View in PubMed

Characterizing sarcoma dominance pattern in uterine carcinosarcoma: Homologous versus heterologous element Surg Oncol. 2018 Sep; 27(3):433-440. . View in PubMed

Nivolumab use for BRCA gene mutation carriers with recurrent epithelial ovarian cancer: A case series Gynecol Oncol Rep. 2018 Aug; 25:98-101. . View in PubMed

Impact of lympho-vascular space invasion on tumor characteristics and survival outcome of women with low-grade serous ovarian carcinoma J Surg Oncol. 2018 Feb; 117(2):236-244. . View in PubMed

Clinical utility of CA-125 in the management of uterine carcinosarcoma J Gynecol Oncol. 2018 11; 29(6):e88. . View in PubMed

Efficacy of Modified Dose-dense Paclitaxel in Recurrent Cervical Cancer Am J Clin Oncol. 2018 09; 41(9):851-860. . View in PubMed

Incidences and risk factors of metachronous vulvar, vaginal, and anal cancers after cervical cancer diagnosis Gynecol Oncol. 2018 09; 150(3):501-508. . View in PubMed

Fully sialylated alpha-chain of complement 4-binding protein (A2160): a novel prognostic marker for epithelial ovarian carcinoma Arch Gynecol Obstet. 2018 03; 297(3):749-756. . View in PubMed

A Phase I Clinical Trial of Guadecitabine and Carboplatin in Platinum-Resistant, Recurrent Ovarian Cancer: Clinical, Pharmacokinetic, and Pharmacodynamic Analyses Clin Cancer Res. 2018 05 15; 24(10):2285-2293. . View in PubMed

Patient compliance for postoperative radiotherapy and survival outcome of women with stage I endometrioid endometrial cancer J Surg Oncol. 2017 Sep; 116(4):482-491. . View in PubMed

Endometrial cancer arising in adenomyosis versus endometrial cancer coexisting with adenomyosis: are these two different entities? Arch Gynecol Obstet. 2017 Jun; 295(6):1459-1468.. View in PubMed

A pilot study in using deep learning to predict limited life expectancy in women with recurrent cervical cancer Am J Obstet Gynecol. 2017 12; 217(6):703-705. . View in PubMed

Impact of adjuvant therapy on recurrence patterns in stage I uterine carcinosarcoma Gynecol Oncol. 2017 04; 145(1):78-87. . View in PubMed

Extent of pelvic lymphadenectomy and use of adjuvant vaginal brachytherapy for early-stage endometrial cancer Gynecol Oncol. 2017 03; 144(3):515-523. . View in PubMed

Ovarian Conservation and Overall Survival in Young Women With Early-Stage Cervical Cancer Obstet Gynecol. 2017 01; 129(1):139-151. . View in PubMed

A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer Int J Cancer. 2016 Dec 15; 139(12):2646-2654. . View in PubMed

Endoplasmic reticulum stress in complex atypical hyperplasia as a possible predictor of occult carcinoma and progestin response Gynecol Oncol. 2016 Dec; 143(3):650-654. . View in PubMed

Association of Low-Dose Aspirin and Survival of Women With Endometrial Cancer Obstet Gynecol. 2016 Jul; 128(1):127-37. . View in PubMed

Ovarian Conservation and Overall Survival in Young Women With Early-Stage Low-Grade Endometrial Cancer Obstet Gynecol. 2016 10; 128(4):761-70. . View in PubMed

Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk Obstet Gynecol. 2016 05; 127(5):828-36. . View in PubMed

Contributing factors for menopausal symptoms after surgical staging for endometrial cancer Menopause. 2016 05; 23(5):535-43. . View in PubMed

Langerhans cells from women with cervical precancerous lesions become functionally responsive against human papillomavirus after activation with stabilized Poly-I:C Clin Immunol. 2015 Dec; 161(2):197-208. . View in PubMed

Impact of depth and extent of lymphovascular space invasion on lymph node metastasis and recurrence patterns in endometrial cancer J Surg Oncol. 2015 Nov; 112(6):669-76. . View in PubMed

Effects of imiquimod on vulvar Paget's disease: a systematic review of literature Gynecol Oncol. 2015 Oct; 139(1):165-71. . View in PubMed

Characteristics of ovarian tumors of low malignant potential in BRCA mutation carriers: A case series Gynecol Oncol Rep. 2015 Aug; 13:36-9. . View in PubMed

In reply Obstet Gynecol. 2015 Jun; 125(6):1498. . View in PubMed

Escalation of oncologic services at the end of life among patients with gynecologic cancer at an urban, public hospital J Oncol Pract. 2015 Mar; 11(2):e163-9. . View in PubMed

Molecular Analysis of Mixed Endometrioid and Serous Adenocarcinoma of the Endometrium PLoS One. 2015; 10(7):e0130909. . View in PubMed

[OUTCOME OF PELVIC EXENTERATION FOR LOCALLY ADVANCED CANCER OF THE PELVIC ORGANS] Vopr Onkol. 2015; 61(3):448-51. . View in PubMed

Phase I clinical trial of temsirolimus and vinorelbine in advanced solid tumors Cancer Chemother Pharmacol. 2014 Dec; 74(6):1227-34. . View in PubMed

Estrogen receptor expression and increased risk of lymphovascular space invasion in high-grade serous ovarian carcinoma Gynecol Oncol. 2014 Jun; 133(3):473-9. . View in PubMed

Effect of lymphovascular space invasion on survival of stage I epithelial ovarian cancer Obstet Gynecol. 2014 May; 123(5):957-65. . View in PubMed

A phase II trial of oxaliplatin, docetaxel, and bevacizumab as first-line therapy of advanced cancer of the ovary, peritoneum, and fallopian tube Gynecol Oncol. 2014 Mar; 132(3):517-25. . View in PubMed

Abdominal aortic resection and Y-graft placement to achieve complete cytoreduction in stage IIIc ovarian carcinoma Obstet Gynecol. 2014 Feb; 123(2 Pt 2 Suppl 2):486-8. . View in PubMed

[Results of surgical treatment of oral cavity cancer T1-2N0M0] Vestn Khir Im I I Grek. 2014; 173(2):52-6. . View in PubMed

Final results from a randomized phase 3 study of FOLFIRI {+/-} panitumumab for second-line treatment of metastatic colorectal cancer Ann Oncol. 2014 Jan; 25(1):107-16. . View in PubMed

[Immediate and long-term results of treatment after pelvic exenteration for locally advanced cervical cancer] Vopr Onkol. 2014; 60(3):319-22. . View in PubMed

Endometrial echo complex thickness in postmenopausal endometrial cancer Gynecol Oncol. 2013 Oct; 131(1):109-12. . View in PubMed

Global, multicenter, randomized, phase II trial of gemcitabine and gemcitabine plus AGS-1C4D4 in patients with previously untreated, metastatic pancreatic cancer Ann Oncol. 2013 Jul; 24(7):1792-801. . View in PubMed

[Microsurgical autografting for reconstruction of head and neck oncological defectsAn analysis of 60 cases]. Vestn Khir Im I I Grek. 2013; 172(1):85-90. . View in PubMed

Long-term pegylated liposomal doxorubicin use and oromaxillary squamous cell carcinoma in endometrial cancer Oncologist. 2012; 17(12):1598-9. . View in PubMed

[Pelvic exenteration in surgery for colorectal cancer] Vopr Onkol. 2012; 58(3):363-8. . View in PubMed

[Characteristics of tumor growth in patients with locally-advanced gastric cancer] Vopr Onkol. 2011; 57(3):370-2. . View in PubMed

Genome-scale screen for DNA methylation-based detection markers for ovarian cancer PLoS One. 2011; 6(12):e28141. . View in PubMed

Overcoming platinum resistance in ovarian carcinoma Expert Opin Investig Drugs. 2010 Nov; 19(11):1339-54. . View in PubMed

Analysis of outcomes of microinvasive adenocarcinoma of the uterine cervix by treatment type Obstet Gynecol. 2010 Nov; 116(5):1150-7. . View in PubMed

Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: a multicenter single-arm phase II study Ann Oncol. 2010 Aug; 21(8):1712-7. . View in PubMed

[Outcomes of surgical treatment for locally advanced gastric cancer] Vopr Onkol. 2010; 56(1):24-8. . View in PubMed

[Quality of life of patients with breast cancer receiving hormonal therapy, depending on age and marital status] Vopr Onkol. 2009; 55(3):310-3. . View in PubMed

[Palliative resection in esophageal cancer] Vopr Onkol. 2009; 55(1):56-9. . View in PubMed

Phase II clinical trial of bevacizumab and low-dose metronomic oral cyclophosphamide in recurrent ovarian cancer: a trial of the California, Chicago, and Princess Margaret Hospital phase II consortia J Clin Oncol. 2008 Jan 01; 26(1):76-82. . View in PubMed

A phase II study of Hsp-7 (SGN-00101) in women with high-grade cervical intraepithelial neoplasia Gynecol Oncol. 2007 Sep; 106(3):558-66. . View in PubMed

Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: potential predictive relationship with tumor HER2 activation status J Clin Oncol. 2006 Sep 10; 24(26):4324-32. . View in PubMed

Feasibility of laparoscopic extraperitoneal surgical staging for locally advanced cervical carcinoma in a gynecologic oncology fellowship training program J Minim Invasive Gynecol. 2006 Sep-Oct; 13(5):391-7. . View in PubMed

Endometrial cancer patients have a significant risk of harboring isolated tumor cells in histologically negative lymph nodes Int J Gynecol Cancer. 2006 May-Jun; 16(3):1336-41. . View in PubMed

Influence of quantity of lymph vascular space invasion on time to recurrence in women with early-stage squamous cancer of the cervix Gynecol Oncol. 2006 Feb; 100(2):288-93. . View in PubMed

Optimal cytoreduction after combined resection and radiofrequency ablation of hepatic metastases from recurrent malignant ovarian tumors Gynecol Oncol. 2005 Apr; 97(1):266-70. . View in PubMed

Phase I clinical trial of topotecan and pegylated liposomal doxorubicin Cancer Invest. 2005; 23(8):665-70. . View in PubMed

Algorithm guides ICP infection investigation Hosp Case Manag. 2004 Nov; 12(11):167-8. . View in PubMed

Extraperitoneal laparoscopic lymph node staging: the University of Southern California experience Gynecol Oncol. 2004 Oct; 95(1):189-92. . View in PubMed

Detection of residual subclinical ovarian carcinoma after completion of adjuvant chemotherapy Clin Cancer Res. 2004 Apr 15; 10(8):2681-6. . View in PubMed

[Comparative clinical evaluation of the effectiveness of modified radical mastectomy and organ-preserving therapy in localized breast cancer (pT1-2N0M0)] Vopr Onkol. 2004; 50(1):99-100. . View in PubMed

A phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive Clin Cancer Res. 2000 Sep; 6(9):3406-16. . View in PubMed

Effects of extended lamivudine therapy in Asian patients with chronic hepatitis BAsia Hepatitis Lamivudine Study Group. Gastroenterology. 2000 Jul; 119(1):172-80. . View in PubMed

[Long-term outcome of surgical treatment of patients with esophageal cancer] Vestn Khir Im I I Grek. 2000; 159(4):33-6. . View in PubMed

A phase II study of gemcitabine and cisplatin in patients with advanced, persistent, or recurrent squamous cell carcinoma of the cervix Gynecol Oncol. 2000 Jan; 76(1):63-6. . View in PubMed

[Ulcerated forms of gastric cancer as a clinical problem] Vestn Khir Im I I Grek. 2000; 159(5):110-3. . View in PubMed

Cold-knife conization versus conization by the loop electrosurgical excision procedure: a randomized, prospective study Am J Obstet Gynecol. 1999 Feb; 180(2 Pt 1):276-82. . View in PubMed

[Lymph node dissection in esophageal cancer] Vestn Khir Im I I Grek. 1999; 158(5):50-3. . View in PubMed

A phase II trial of CPT-11 in recurrent squamous carcinoma of the cervix: a gynecologic oncology group study Gynecol Oncol. 1998 Sep; 70(3):334-8. . View in PubMed

Clinical utility? J Reprod Med. 1998 May; 43(5):403-7.. View in PubMed

Influence of quantity of lymph-vascular space invasion on the risk of nodal metastases in women with early-stage squamous cancer of the cervix Gynecol Oncol. 1998 Mar; 68(3):220-5. . View in PubMed

Detection of ovarian cancer cells: comparison of a telomerase assay and cytologic examination J Natl Cancer Inst. 1998 Feb 04; 90(3):238-42. . View in PubMed

Phase I/II study of intraperitoneal floxuridine and platinums (cisplatin and/or carboplatin) Gynecol Oncol. 1997 Aug; 66(2):290-4. . View in PubMed

Carboplatin as a radiation sensitizer in locally advanced cervical cancer: a pilot study Gynecol Oncol. 1997 May; 65(2):336-42. . View in PubMed

Pelvic examination, tumor marker level, and gray-scale and Doppler sonography in the prediction of pelvic cancer Obstet Gynecol. 1997 Apr; 89(4):493-500. . View in PubMed

[Successful surgical treatment of cancer with multiple location] Vopr Onkol. 1997; 43(2):230. . View in PubMed

[Variants in the definitive organization of the lumbar lymph-conducting pathways in the applied aspect] Vestn Khir Im I I Grek. 1996; 155(6):49-53. . View in PubMed

Differentiation of benign and malignant adnexal masses: relative value of gray-scale, color Doppler, and spectral Doppler sonography AJR Am J Roentgenol. 1995 Feb; 164(2):381-6. . View in PubMed

Intraperitoneal 5-fluoro-2'-deoxyuridine (FUDR) and (S)-leucovorin for disease predominantly confined to the peritoneal cavity: a pharmacokinetic and toxicity study Cancer Chemother Pharmacol. 1995; 37(1-2):32-8. . View in PubMed

Paclitaxel (Taxol) in heavily pretreated ovarian cancer: antitumor activity and complications Ann Oncol. 1994 Nov; 5(9):827-33. . View in PubMed

Death from anaphylaxis to cisplatin: a case report Gynecol Oncol. 1994 Apr; 53(1):121-2. . View in PubMed

Cervical cancer in pregnancy: reporting on planned delay in therapy Obstet Gynecol. 1993 Oct; 82(4 Pt 1):598-602. . View in PubMed

Dedifferentiated extrauterine adenosarcoma responsive to chemotherapy Gynecol Oncol. 1993 Jun; 49(3):389-94. . View in PubMed

High-dose, short-duration cisplatin/doxorubicin combination chemotherapy for advanced ovarian epithelial cancer Cancer. 1991 Nov 01; 68(9):1890-4. . View in PubMed

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