Keck School Faculty

Michael A Schumacher

Michael A Schumacher

Assistant Professor of Research Pediatrics
Medicine
4640 West Sunset Blvd Off Campus Los Angeles

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Sonic Hedgehog acts as a macrophage chemoattractant during regeneration of the gastric epithelium NPJ Regen Med. 2022 Jan 12; 7(1):3. . View in PubMed

Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3ß-mediated restriction of epithelial IL-33 Nat Commun. 2021 02 05; 12(1):836. . View in PubMed

NRG4-ErbB4 signaling represses proinflammatory macrophage activity Am J Physiol Gastrointest Liver Physiol. 2021 06 01; 320(6):G990-G1001. . View in PubMed

Growth Factors in the Intestinal Tract in Physiology of the Gastrointestinal Tract 2018; 71-101. . View in PubMed

The ErbB3 receptor tyrosine kinase negatively regulates Paneth cells by PI3K-dependent suppression of Atoh1 Cell Death Differ. 2017 05; 24(5):855-865. . View in PubMed

ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation Cell Death Dis. 2017 02 23; 8(2):e2622. . View in PubMed

Co-culture of Gastric Organoids and Immortalized Stomach Mesenchymal Cells Methods Mol Biol. 2016; 1422:23-31. . View in PubMed

Characterization of stem/progenitor cell cycle using murine circumvallate papilla taste bud organoid Sci Rep. 2015 Nov 24; 5:17185. . View in PubMed

Helicobacter pylori targets cancer-associated apical-junctional constituents in gastroids and gastric epithelial cells Gut. 2015 May; 64(5):720-30. . View in PubMed

The use of murine-derived fundic organoids in studies of gastric physiology J Physiol. 2015 Apr 15; 593(8):1809-27. . View in PubMed

Helicobacter. 2015 Feb; 20(1):19-28. . View in PubMed

CD44 plays a functional role in Helicobacter pylori-induced epithelial cell proliferation PLoS Pathog. 2015 Feb; 11(2):e1004663. . View in PubMed

Modelling human development and disease in pluripotent stem-cell-derived gastric organoids Nature. 2014 Dec 18; 516(7531):400-4. . View in PubMed

Motility and chemotaxis mediate the preferential colonization of gastric injury sites by Helicobacter pylori PLoS Pathog. 2014 Jul; 10(7):e1004275. . View in PubMed

Gastritis promotes an activated bone marrow-derived mesenchymal stem cell with a phenotype reminiscent of a cancer-promoting cell Dig Dis Sci. 2014 Mar; 59(3):569-82. . View in PubMed

Crosstalks between cytokines and Sonic Hedgehog in Helicobacter pylori infection: a mathematical model PLoS One. 2014; 9(11):e111338. . View in PubMed

Establishment of Gastrointestinal Epithelial Organoids Curr Protoc Mouse Biol. 2013 Dec 19; 3(4):217-40. . View in PubMed

Sonic Hedgehog contributes to gastric mucosal restitution after injury Lab Invest. 2013 Jan; 93(1):96-111. . View in PubMed

Gastric Sonic Hedgehog acts as a macrophage chemoattractant during the immune response to Helicobacter pyloriGastroenterology. 2012 May; 142(5):1150-1159. e6. . View in PubMed

Chronic maternal infusion of full-length adiponectin in pregnant mice down-regulates placental amino acid transporter activity and expression and decreases fetal growth J Physiol. 2012 Mar 15; 590(6):1495-509. . View in PubMed

Techniques for following labeled cells in vivo: use of X/Y FISH, techniques to optimize fluorescent detection, and beta-galactosidase detection Methods Mol Biol. 2012; 921:227-38. . View in PubMed

Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions Am J Physiol Gastrointest Liver Physiol. 2010 Dec; 299(6):G1252-65. . View in PubMed

Loss of parietal cell expression of Sonic hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cellsGastroenterology. 2010 Feb; 138(2):550-61561. e1-8. . View in PubMed

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