Keck School Faculty

Robert Shaddy

Robert Shaddy

Chair and Professor of Pediatrics
4640 West Sunset Blvd Off Campus Los Angeles

Baseline Characteristics of Pediatric Patients With Heart Failure Due to Systemic Left Ventricular Systolic Dysfunction in the PANORAMA-HF Trial Circ Heart Fail. 2023 03; 16(3):e009816. . View in PubMed

Drug Treatment of Heart Failure in Children: Gaps and Opportunities Paediatr Drugs. 2022 Mar; 24(2):121-136. . View in PubMed

Recent and Upcoming Drug Therapies for Pediatric Heart Failure Front Pediatr. 2021; 9:681224. . View in PubMed

Elevated Heart Rate and Survival in Children With Dilated Cardiomyopathy: A Multicenter Study From the Pediatric Cardiomyopathy Registry J Am Heart Assoc. 2020 08 04; 9(15):e015916. . View in PubMed

Hospital readmission following pediatric heart transplantation Pediatr Transplant. 2019 11; 23(7):e13561. . View in PubMed

Update on pediatric heart failure Curr Opin Pediatr. 2019 10; 31(5):598-603. . View in PubMed

Early outcomes for low-risk pediatric heart transplant recipients and steroid avoidance: A multicenter cohort study (Clinical Trials in Organ Transplantation in Children - CTOTC-04) J Heart Lung Transplant. 2019 09; 38(9):972-981. . View in PubMed

Systematic literature review on the economic, humanistic, and societal burden of heart failure in children and adolescents Expert Rev Pharmacoecon Outcomes Res. 2019 08; 19(4):397-408. . View in PubMed

Significant mortality, morbidity and resource utilization associated with advanced heart failure in congenital heart disease in children and young adults Am Heart J. 2019 03; 209:9-19. . View in PubMed

Elevated Troponin in the First 72 h of Hospitalization for Pediatric Viral Myocarditis is Associated with ECMO: An Analysis of the PHIS+ Database Pediatr Cardiol. 2018 Aug; 39(6):1139-1143. . View in PubMed

Disopyramide use in infants and children with hypertrophic cardiomyopathy Cardiol Young. 2018 Apr; 28(4):530-535. . View in PubMed

Systematic Literature Review on the Incidence and Prevalence of Heart Failure in Children and Adolescents Pediatr Cardiol. 2018 Mar; 39(3):415-436. . View in PubMed

Study rationale, design, and pretransplantation alloantibody status: A first report of Clinical Trials in Organ Transplantation in Children-04 (CTOTC-04) in pediatric heart transplantation Am J Transplant. 2018 09; 18(9):2135-2147. . View in PubMed

Pediatric heart transplantation across a positive crossmatch: First year results from the CTOTC-04 multi-institutional study Am J Transplant. 2018 09; 18(9):2148-2162. . View in PubMed

Incidence, characterization, and impact of newly detected donor-specific anti-HLA antibody in the first year after pediatric heart transplantation: A report from the CTOTC-04 study Am J Transplant. 2018 09; 18(9):2163-2174. . View in PubMed

Cumulative Effect of Preoperative Risk Factors on Mortality After Pediatric Heart Transplantation Ann Thorac Surg. 2018 08; 106(2):561-566. . View in PubMed

Characteristics and Outcomes of Pediatric Heart Failure-Related Emergency Department Visits in the United States: A Population-Based StudyJ Pediatr. 2018 02; 193:114-118. e3. . View in PubMed

Recommendations to Enhance Pediatric Cardiovascular Drug Development: Report of a Multi-Stakeholder Think Tank J Am Heart Assoc. 2018 02 10; 7(4). . View in PubMed

Design for the sacubitril/valsartan (LCZ696) compared with enalapril study of pediatric patients with heart failure due to systemic left ventricle systolic dysfunction (PANORAMA-HF study) Am Heart J. 2017 Nov; 193:23-34. . View in PubMed

Value of a flow cytometry cross-match in the setting of a negative complement-dependent cytotoxicity cross-match in heart transplant recipients Clin Transplant. 2017 Oct; 31(10). . View in PubMed

Emergency department utilization in pediatric heart transplant recipients Pediatr Transplant. 2017 Jun; 21(4). . View in PubMed

Prevalence and Severity of Anemia in Children Hospitalized with Acute Heart Failure Congenit Heart Dis. 2016 Dec; 11(6):622-629. . View in PubMed

Incidence, Severity, and Association With Adverse Outcome of Hyponatremia in Children Hospitalized With Heart Failure Am J Cardiol. 2016 Oct 01; 118(7):1006-10. . View in PubMed

Left Ventricular Rotational Mechanics in Children After Heart Transplantation Circ Cardiovasc Imaging. 2016 09; 9(9). . View in PubMed

Donation after circulatory death in pediatric patients: Current utilization in the United States J Heart Lung Transplant. 2016 09; 35(9):1131-2. . View in PubMed

Heart Transplantation-The Pediatric Cardiac Critical Care Perspective Pediatr Crit Care Med. 2016 08; 17(8 Suppl 1):S171-7. . View in PubMed

Postoperative management of heart failure in pediatric patients Expert Rev Cardiovasc Ther. 2016; 14(2):201-15. . View in PubMed

Heart Retransplant Recipients Have Better Survival With Concurrent Kidney Transplant Than With Heart Retransplant Alone J Am Heart Assoc. 2015 Dec 11; 4(12). . View in PubMed

Changes in the methodology of pre-heart transplant human leukocyte antibody assessment: an analysis of the United Network for Organ Sharing database Clin Transplant. 2015 Sep; 29(9):842-50. . View in PubMed

The Use of Pediatric Ventricular Assist Devices in Children's Hospitals From 2000 to 2010: Morbidity, Mortality, and Hospital Charges Pediatr Crit Care Med. 2015 Jul; 16(6):522-8. . View in PubMed

Pediatric versus adult cardiomyopathy and heart failure-related hospitalizations: a value-based analysis J Card Fail. 2015 Jan; 21(1):76-82. . View in PubMed

Renal function assessment in child and adolescent heart transplant recipients during routine cardiac catheterization Pediatr Transplant. 2014 Nov; 18(7):757-63. . View in PubMed

Retrospective analysis of beta-blocker instituted for treatment of hemangiomas (RABBIT study) Clin Pediatr (Phila). 2014 Oct; 53(11):1084-90. . View in PubMed

The International Society for Heart and Lung Transplantation Guidelines for the management of pediatric heart failure: Executive summary[Corrected]. J Heart Lung Transplant. 2014 Sep; 33(9):888-909. . View in PubMed

Adolescent age and heart transplantation outcomes in myocarditis or congenital heart disease J Heart Lung Transplant. 2014 Sep; 33(9):943-9. . View in PubMed

Heart failure in children: etiology and treatment J Pediatr. 2014 Aug; 165(2):228-33. . View in PubMed

Impact of congenital heart disease on outcomes of pediatric heart-lung transplantation Pediatr Transplant. 2014 Mar; 18(2):204-10. . View in PubMed

A tool to measure shared clinical understanding following handoffs to help evaluate handoff quality J Hosp Med. 2014 Mar; 9(3):142-7. . View in PubMed

Update on pharmacological heart failure therapies in children: do adult medications work in children and if not, why not? Circulation. 2014 Feb 04; 129(5):607-12.. View in PubMed

Heart transplant after the Fontan operation Cardiol Young. 2013 Dec; 23(6):841-6. . View in PubMed

Pediatric heart transplantation from donors with depressed ventricular function: an analysis of the United Network of Organ Sharing Database Circ Heart Fail. 2013 Nov; 6(6):1223-9. . View in PubMed

Persistence of anti-human leukocyte antibodies in congenital heart disease late after surgery using allografts and whole blood J Heart Lung Transplant. 2013 Apr; 32(4):390-7. . View in PubMed

Hypertrophic cardiomyopathy: do sudden death prevention strategies in children differ between Europe and North America? Curr Opin Cardiol. 2013 Mar; 28(2):130-8.. View in PubMed

Common data elements for clinical research in Friedreich's ataxia Mov Disord. 2013 Feb; 28(2):190-5. . View in PubMed

Allosensitization and outcomes in pediatric heart transplantation J Heart Lung Transplant. 2011 Nov; 30(11):1221-7. . View in PubMed

Troponin I levels from donors accepted for pediatric heart transplantation do not predict recipient graft survival J Heart Lung Transplant. 2011 Aug; 30(8):920-7. . View in PubMed

Ventricular remodeling and survival are more favorable for myocarditis than for idiopathic dilated cardiomyopathy in childhood: an outcomes study from the Pediatric Cardiomyopathy Registry Circ Heart Fail. 2010 Nov; 3(6):689-97. . View in PubMed

Clinical performance of decellularized cryopreserved valved allografts compared with standard allografts in the right ventricular outflow tract Ann Thorac Surg. 2010 Oct; 90(4):1301-5; discussion 1306. . View in PubMed

BNP levels predict outcome in pediatric heart failure patients: post hoc analysis of the Pediatric Carvedilol Trial Circ Heart Fail. 2010 Sep; 3(5):606-11. . View in PubMed

Echocardiographic evaluation of children with systemic ventricular dysfunction treated with carvedilol Pediatr Cardiol. 2010 Aug; 31(6):780-4. . View in PubMed

Wasting or obesity at time of transplant does not predict pediatric heart transplant outcomes: analysis of ISHLT pediatric heart transplant registry J Heart Lung Transplant. 2009 Dec; 28(12):1273-8. . View in PubMed

Applying heart failure guidelines to adult congenital heart disease patients Expert Rev Cardiovasc Ther. 2008 Feb; 6(2):165-74. . View in PubMed

Prognostic value of B-type natriuretic peptide in surgical palliation of children with single-ventricle congenital heart disease Pediatr Cardiol. 2008 Jan; 29(1):70-5. . View in PubMed

Carvedilol for children and adolescents with heart failure: a randomized controlled trial JAMA. 2007 Sep 12; 298(10):1171-9. . View in PubMed

Indications for heart transplantation in pediatric heart disease: a scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young; the Councils on Clinical Cardiology, Cardiovascular Nursing, and Cardiovascular Surgery and Anesthesia; and the Quality of Care and Outcomes Research Interdisciplinary Working Group Circulation. 2007 Feb 06; 115(5):658-76. . View in PubMed

Drug trials in pediatric heart failure: hype or improved clinical science? Future Cardiol. 2006 May; 2(3):281-6.. View in PubMed

Ventricular remodeling in children with left ventricular dysfunction secondary to various cardiomyopathies Am J Cardiol. 2005 Oct 15; 96(8):1157-61. . View in PubMed

Two-year reduction of panel reactive human leukocyte antigen antibodies in children receiving mycophenolate mofetil after valved allograft placement Transplantation. 2005 Aug 15; 80(3):414-6. . View in PubMed

The impact and outcome of transplant coronary artery disease in a pediatric population: a 9-year multi-institutional study J Heart Lung Transplant. 2005 Jun; 24(6):645-51. . View in PubMed

Panel-reactive antibodies late after allograft implantation in children Ann Thorac Surg. 2005 Feb; 79(2):641-4; discussion 645. . View in PubMed

International Society for Heart and Lung Transplantation: Practice guidelines for management of heart failure in children J Heart Lung Transplant. 2004 Dec; 23(12):1313-33. . View in PubMed

B-type natriuretic peptide levels in congenital heart disease Pediatr Cardiol. 2004 Jul-Aug; 25(4):336-40. . View in PubMed

Rheumatic fever in children younger than 5 years: is the presentation different? Pediatrics. 2003 Nov; 112(5):1065-8.. View in PubMed

Safety of endomyocardial biopsy in children Cardiol Young. 2003 Oct; 13(5):404-7. . View in PubMed

Immunogenicity of decellularized cryopreserved allografts in pediatric cardiac surgery: comparison with standard cryopreserved allografts J Thorac Cardiovasc Surg. 2003 Jul; 126(1):247-52; discussion 252-3. . View in PubMed

QT dispersion after beta-blocker therapy (carvedilol or metoprolol) in children with heart failure Am J Cardiol. 2003 Jun 15; 91(12):1497-500A8. . View in PubMed

Spectrum of left ventricular dysfunction in potential pediatric heart transplant donors J Heart Lung Transplant. 2003 May; 22(5):548-52. . View in PubMed

Evidence for lack of myocardial injury in children with acute rheumatic carditis Cardiol Young. 2002 Dec; 12(6):519-23. . View in PubMed

The Pediatric Randomized Carvedilol Trial in Children with Heart Failure: rationale and design Am Heart J. 2002 Sep; 144(3):383-9. . View in PubMed

Intermediate effects of treatment with metoprolol or carvedilol in children with left ventricular systolic dysfunction J Heart Lung Transplant. 2002 Aug; 21(8):906-9. . View in PubMed

Complete follow-up echocardiograms are needed to detect stenosis of normally connecting pulmonary veins Echocardiography. 2001 Oct; 18(7):589-92. . View in PubMed

Carvedilol as therapy in pediatric heart failure: an initial multicenter experience J Pediatr. 2001 Apr; 138(4):505-11. . View in PubMed

Evidence for early vessel involvement in the dysfunctional myocardium of Takayasu's arteritis Pediatr Cardiol. 2001 Jan-Feb; 22(1):74-6. . View in PubMed

Usefulness of doppler echocardiography to determine the timing of surgery for supravalvar aortic stenosis Am J Cardiol. 2000 Jul 01; 86(1):114-6. . View in PubMed

An unusual variant of total anomalous pulmonary venous connection with varices and multiple drainage sites Pediatr Cardiol. 2000 May-Jun; 21(3):289-91. . View in PubMed

Spectrum and influence of hypoplasia of the left heart in neonatal aortic coarctation Cardiol Young. 2000 Mar; 10(2):90-7. . View in PubMed

Can Doppler systemic venous flow indices predict central venous pressure in children? Echocardiography. 2000 Feb; 17(2):127-32.. View in PubMed

Class I and class II anti-HLA antibodies after implantation of cryopreserved allograft material in pediatric patients J Thorac Cardiovasc Surg. 2000 Feb; 119(2):324-30. . View in PubMed

Heart transplantation in children: indicationsReport of the Ad Hoc Subcommittee of the Pediatric Committee of the American Society of Transplantation (AST). Pediatr Transplant. 1999 Nov; 3(4):333-42. . View in PubMed

Influence of left ventricular cavity size on interventricular shunt timing and outcome in neonates with coarctation of the aorta and ventricular septal defect Am J Cardiol. 1999 Sep 15; 84(6):750-2A9. . View in PubMed

Pulmonary vein stenosis with normal connection: associated cardiac abnormalities and variable outcome Ann Thorac Surg. 1999 Jul; 68(1):164-8. . View in PubMed

Left heart hypoplasia and neonatal aortic arch obstruction: is the Rhodes left ventricular adequacy score applicable? J Thorac Cardiovasc Surg. 1999 Jul; 118(1):81-6.. View in PubMed

Beta-blocker treatment of dilated cardiomyopathy with congestive heart failure in children: a multi-institutional experience J Heart Lung Transplant. 1999 Mar; 18(3):269-74. . View in PubMed

Cardiovascular monitoring of children and adolescents receiving psychotropic drugs: A statement for healthcare professionals from the Committee on Congenital Cardiac Defects, Council on Cardiovascular Disease in the Young, American Heart Association Circulation. 1999 Feb 23; 99(7):979-82. . View in PubMed

Beta-blocker therapy in young children with congestive heart failure under consideration for heart transplantation Am Heart J. 1998 Jul; 136(1):19-21. . View in PubMed

Common cardiovascular problems in the young: Part IMurmurs, chest pain, syncope and irregular rhythms. Am Fam Physician. 1997 Nov 01; 56(7):1825-30. . View in PubMed

Persistence of human leukocyte antigen (HLA) antibodies after one year in children receiving cryopreserved valved allografts Am J Cardiol. 1997 Aug 01; 80(3):358-9. . View in PubMed

A novel approach to pediatric intraaortic balloon pump timing using M-mode echocardiography Am J Cardiol. 1997 Aug 01; 80(3):367-9. . View in PubMed

Predicting outcome after listing for heart transplantation in children: comparison of Kaplan-Meier and parametric competing risk analysisPediatric Heart Transplant Study Group. J Heart Lung Transplant. 1997 Jul; 16(7):713-22. . View in PubMed

Possibility of postnatal left ventricular growth in selected infants with non-apex-forming left ventricles Am Heart J. 1997 May; 133(5):570-4. . View in PubMed

Outcome of cardiac transplantation in childrenSurvival in a contemporary multi-institutional experience. Pediatric Heart Transplant Study. Circulation. 1996 Nov 01; 94(9 Suppl):II69-73. . View in PubMed

Doppler systemic venous flow patterns: changes in children with mild/moderate pulmonic stenosis J Am Soc Echocardiogr. 1996 Nov-Dec; 9(6):814-8. . View in PubMed

Etiology and outcome of outpatient fevers in pediatric heart transplant patients Clin Pediatr (Phila). 1996 Sep; 35(9):437-42. . View in PubMed

Prospective analysis of HLA immunogenicity of cryopreserved valved allografts used in pediatric heart surgery Circulation. 1996 Sep 01; 94(5):1063-7. . View in PubMed

Aortic valve repair and replacement after balloon aortic valvuloplasty in children Ann Thorac Surg. 1996 May; 61(5):1355-8. . View in PubMed

Sinus node dysfunction in tuberous sclerosis Pediatr Cardiol. 1996 Jan-Feb; 17(1):51-2. . View in PubMed

Use of echocardiography for detecting aortic valve leaflet avulsion and predicting repair potential after balloon valvuloplasty Am J Cardiol. 1995 Mar 01; 75(7):533-5. . View in PubMed

Efficacy and safety of metoprolol in the treatment of doxorubicin-induced cardiomyopathy in pediatric patients Am Heart J. 1995 Jan; 129(1):197-9. . View in PubMed

Guidelines for evaluation and management of common congenital cardiac problems in infants, children, and adolescentsA statement for healthcare professionals from the Committee on Congenital Cardiac Defects of the Council on Cardiovascular Disease in the Young, American Heart Association. Circulation. 1994 Oct; 90(4):2180-8. . View in PubMed

Mid-term results after bidirectional cavopulmonary shunts Ann Thorac Surg. 1993 Oct; 56(4):833-7. . View in PubMed

Comparison of angioplasty and surgery for unoperated coarctation of the aorta Circulation. 1993 Mar; 87(3):793-9. . View in PubMed

Acute life-threatening hypertension following balloon angioplasty of native coarctation of the aorta Am Heart J. 1993 Mar; 125(3):907-8. . View in PubMed

Efficacy of 100 consecutive right ventricular endomyocardial biopsies in pediatric patients using the right internal jugular venous approach Pediatr Cardiol. 1993 Jan; 14(1):5-8. . View in PubMed

Relaxation and imagery techniques without sedation during right ventricular endomyocardial biopsy in pediatric heart transplant patients J Heart Lung Transplant. 1993 Jan-Feb; 12(1 Pt 1):59-62. . View in PubMed

Gradient reduction, aortic valve regurgitation and prolapse after balloon aortic valvuloplasty in 32 consecutive patients with congenital aortic stenosis J Am Coll Cardiol. 1990 Aug; 16(2):451-6. . View in PubMed

The effects of changes in heart rate and aortic systolic pressure on left ventricular myocardial oxygen consumption in lambs J Dev Physiol. 1989 Apr; 11(4):213-7. . View in PubMed

Pulsed Doppler findings in patients with coarctation of the aorta Circulation. 1986 Jan; 73(1):82-8. . View in PubMed

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