Keck School Faculty

Russell K. Brynes, MD
Russell K. Brynes, MD
Professor of Clinical Pathology
GNH 1200 North State Street Off Campus Los Angeles

Gelatinous bone marrow transformation and emergence of clonal Philadelphia-negative cytogenetic abnormalities with excess blasts in a patient with chronic myeloid leukemia treated with dasatinib Anticancer Drugs. 2019 Apr; 30(4):416-421. . View in PubMed

Digital image analysis agrees with visual estimates of adult bone marrow trephine biopsy cellularity Int J Lab Hematol. 2018 Apr; 40(2):209-214. . View in PubMed

Autoimmune Myelofibrosis: Clinical Features, Course, and Outcome Acta Haematol. 2017; 138(3):129-137. . View in PubMed

A 2-Year, Longitudinal, Prospective Study of the Effects of Eltrombopag on Bone Marrow in Patients with Chronic Immune Thrombocytopenia Acta Haematol. 2017; 137(2):66-72. . View in PubMed

Large soft-tissue masses in an adult patient with Gaucher disease J Inherit Metab Dis. 2016 Nov; 39(6):887-888. . View in PubMed

Bone marrow cellularity MRI calculation and correlation with bone marrow biopsy Clin Imaging. 2016 May-Jun; 40(3):392-7. . View in PubMed

Pegylated interferon for the treatment of early myelofibrosis: correlation of serial laboratory studies with response to therapy Ann Hematol. 2016 Apr; 95(5):733-8. . View in PubMed

Preleukemic phase of chronic myelogenous leukemia: morphologic and immunohistochemical characterization of 7 cases Ann Diagn Pathol. 2016 Apr; 21:53-8. . View in PubMed

Large soft-tissue masses in an adult patient with Gaucher disease J Inherit Metab Dis. 2016 11; 39(6):887-888. . View in PubMed

Characterization of a variant of t(14;18) negative nodal diffuse follicular lymphoma with CD23 expression, 1p36/TNFRSF14 abnormalities, and STAT6 mutations Mod Pathol. 2016 06; 29(6):570-81. . View in PubMed

Recommendations for gross examination and sampling of surgical specimens of the spleen Ann Diagn Pathol. 2015 Oct; 19(5):288-95. . View in PubMed

ICSH guidelines for the standardization of bone marrow immunohistochemistry Int J Lab Hematol. 2015 Aug; 37(4):431-49. . View in PubMed

Evaluation of bone marrow reticulin in patients with chronic immune thrombocytopenia treated with eltrombopag: Data from the EXTEND study Am J Hematol. 2015 Jul; 90(7):598-601. . View in PubMed

Differentiating benign from malignant bone marrow B-cell lymphoid aggregates: a statistical analysis of distinguishing features Arch Pathol Lab Med. 2015 Feb; 139(2):233-40. . View in PubMed

Autoimmune myelofibrosis: an update on morphologic features in 29 cases and review of the literature Hum Pathol. 2014 Nov; 45(11):2183-91. . View in PubMed

Composite lymphoid neoplasm of B-cell and T-cell origins: a pathologic study of 14 cases Hum Pathol. 2014 Apr; 45(4):768-84. . View in PubMed

Peripheral blood smears, bone marrow aspiration, trephine and clot biopsies: methods and protocols Methods Mol Biol. 2014; 1180:257-69. . View in PubMed

Aplastic anemia secondary to azathioprine in systemic lupus erythematosus: report of a case with normal thiopurine S-methyltransferase enzyme activity and review of the literature Lupus. 2013 Dec; 22(14):1526-8. . View in PubMed

Characterization of bone marrow mast cells in acute myeloid leukemia with t(8;21) (q22;q22); RUNX1-RUNX1T1 Leuk Res. 2013 Nov; 37(11):1572-5. . View in PubMed

Classical Hodgkin lymphoma arising in the setting of iatrogenic immunodeficiency: a clinicopathologic study of 10 cases Am J Surg Pathol. 2013 Aug; 37(8):1290-7. . View in PubMed

Benign lymphoid aggregates in the bone marrow: distribution patterns of B and T lymphocytes Hum Pathol. 2013 Apr; 44(4):512-20. . View in PubMed

Histopathological findings in 29 lymph node biopsies with increased IgG4 plasma cells Mod Pathol. 2012 Mar; 25(3):480-91. . View in PubMed

Spontaneous, transient regression of B lymphoblastic leukemia in an adult patient: a variant presentation of prodromal/pre-ALL Leuk Res. 2012 Mar; 36(3):e57-9. . View in PubMed

B-cell lymphoma with hyaline vascular Castleman disease-like features: a clinicopathologic study Am J Clin Pathol. 2011 Jun; 135(6):901-14. . View in PubMed

Adult leukemic synovitis is associated with leukemia of monocytic differentiation J Clin Rheumatol. 2011 Apr; 17(3):130-4. . View in PubMed

Peripheral blood polyclonal plasmacytosis mimicking plasma cell leukemia in patients with angioimmunoblastic T-cell lymphoma: report of 3 cases and review of the literature Int J Clin Exp Pathol. 2011 Apr; 4(4):416-20. . View in PubMed

Phlegmonous gastritis in a patient with myeloid sarcoma: a case report Appl Immunohistochem Mol Morphol. 2009 Oct; 17(5):458-62. . View in PubMed

Systemic mastocytosis associated with t(8;21)(q22;q22) acute myeloid leukemia J Hematop. 2009 Mar; 2(1):27-33. . View in PubMed

High lifetime incidence of adult acute lymphoblastic leukemia among Hispanics in California Cancer Epidemiol Biomarkers Prev. 2009 Feb; 18(2):611-5. . View in PubMed

Indeterminate cell tumor: a rare dendritic neoplasm Am J Surg Pathol. 2008 Dec; 32(12):1868-76. . View in PubMed

Ki67 expression in different epithelial types in columnar lined oesophagus indicates varying levels of expanded and aberrant proliferative patterns Histopathology. 2005 Aug; 47(2):132-40. . View in PubMed

Body cavity-based presentation of natural killer cell lymphoma Leuk Lymphoma. 2005 Feb; 46(2):293-6. . View in PubMed

beta-Catenin expression in thyroid follicular lesions: potential role in nuclear envelope changes in papillary carcinomas Endocr Pathol. 2004; 15(4):329-37. . View in PubMed

Systemic mastocytosis with associated clonal hematological non-mast-cell lineage disease: analysis of clinicopathologic features and activating c-kit mutations Am J Hematol. 2003 May; 73(1):12-7. . View in PubMed

Primary autoimmune myelofibrosis: definition of a distinct clinicopathologic syndrome Am J Hematol. 2003 Jan; 72(1):8-12. . View in PubMed

Immunohistochemical expression of the transcription factor DP-1 and its heterodimeric partner E2F-1 in non-Hodgkin lymphoma Appl Immunohistochem Mol Morphol. 2002 Dec; 10(4):322-6. . View in PubMed

Immunohistochemical expression of cyclin D1, E2F-1, and Ki-67 in benign and malignant thyroid lesions J Pathol. 2002 Oct; 198(2):157-62. . View in PubMed

Reduced risk of synovial sarcoma in females: X-chromosome inactivation? Br J Cancer. 2002 Jul 01; 87(1):28-30.. View in PubMed

Clinical, immunologic, and pathologic correlates of bone marrow involvement in 291 patients with acquired immunodeficiency syndrome-related lymphoma Blood. 2001 Oct 15; 98(8):2358-63. . View in PubMed

Immunohistochemical expression of cell cycle proteins E2F-1, Cdk-2, Cyclin E, p27(kip1), and Ki-67 in normal placenta and gestational trophoblastic disease Mod Pathol. 2001 Oct; 14(10):1036-42. . View in PubMed

Hyperplasia of mantle/marginal zone B cells with clear cytoplasm in peripheral lymph nodesA clinicopathologic study of 35 cases. Am J Clin Pathol. 2001 Oct; 116(4):550-9. . View in PubMed

DNA topoisomerase IIalpha in multiple myeloma: a marker of cell proliferation and not drug resistance Mod Pathol. 2001 Sep; 14(9):886-91. . View in PubMed

Pathology of autoimmune myelofibrosisA report of three cases and a review of the literature. Am J Clin Pathol. 2001 Aug; 116(2):211-6. . View in PubMed

Cyclin D1 and E2F-1 immunoreactivity in bone marrow biopsy specimens of multiple myeloma: relationship to proliferative activity, cytogenetic abnormalities and DNA ploidy Br J Haematol. 2001 Mar; 112(3):776-82. . View in PubMed

Cyclin D1 expression in dysplastic nevi: an immunohistochemical study Arch Pathol Lab Med. 2001 Feb; 125(2):208-10. . View in PubMed

Mast cell disease associated with acute myeloid leukemia: detection of a new c-kit mutation Asp816His Am J Hematol. 2000 Dec; 65(4):307-9. . View in PubMed

Intravascular large B-cell lymphomaA report of five cases initially diagnosed by bone marrow biopsy. Am J Clin Pathol. 1999 Aug; 112(2):248-55. . View in PubMed

Expression of cyclin D1 in parathyroid carcinomas, adenomas, and hyperplasias: a paraffin immunohistochemical study Mod Pathol. 1999 Apr; 12(4):412-6. . View in PubMed

Acute lymphoblastic leukemiaSurvey of immunophenotype, French-American-British classification, frequency of myeloid antigen expression, and karyotypic abnormalities in 210 pediatric and adult cases. Am J Clin Pathol. 1999 Apr; 111(4):467-76. . View in PubMed

Cyclin D1 overexpression in Spitz nevi: an immunohistochemical study Am J Dermatopathol. 1999 Apr; 21(2):115-20. . View in PubMed

Differential expression of cyclin D1 in breast papillary carcinomas and benign papillomas: an immunohistochemical study Arch Pathol Lab Med. 1999 Feb; 123(2):152-6. . View in PubMed

Cyclin D1 expression in renal carcinomas and oncocytomas: an immunohistochemical study Mod Pathol. 1998 Nov; 11(11):1075-81. . View in PubMed

Intravascular large B-cell lymphoma: the CD5 antigen is expressed by a subset of cases Mod Pathol. 1998 Oct; 11(10):983-8. . View in PubMed

Surface immunoglobulin light chain-positive acute lymphoblastic leukemia of FAB L1 or L2 type: a report of 6 cases in adults Am J Clin Pathol. 1998 Aug; 110(2):143-9. . View in PubMed

Expression of the cell-cycle-related proteins E2F-1, p53, mdm-2, p21waf-1, and Ki-67 in multiple myeloma: correlation with cyclin-D1 immunoreactivity Mod Pathol. 1998 Jul; 11(7):642-7. . View in PubMed

Immunohistochemical detection of E2F-1 in non-Hodgkin's lymphomas: a survey of 124 cases Mod Pathol. 1998 May; 11(5):457-63. . View in PubMed

The immunophenotype of adult acute myeloid leukemia: high frequency of lymphoid antigen expression and comparison of immunophenotype, French-American-British classification, and karyotypic abnormalities Am J Clin Pathol. 1998 Feb; 109(2):211-20. . View in PubMed

Expression of p53, MDM2, p21waf1, bcl-2, and retinoblastoma gene proteins in myelodysplastic syndrome after autologous bone marrow transplantation for lymphoma Mod Pathol. 1997 Nov; 10(11):1120-7. . View in PubMed

Myelodysplastic syndrome occurring after autologous bone marrow transplantation for lymphomaMorphologic features. Am J Clin Pathol. 1997 Oct; 108(4):369-77. . View in PubMed

Cyclin D1 immunohistochemical staining is useful in distinguishing mantle cell lymphoma from other low-grade B-cell neoplasms in bone marrow Am J Clin Pathol. 1997 Sep; 108(3):302-7. . View in PubMed

Cyclin D1 protein in multiple myeloma and plasmacytoma: an immunohistochemical study using fixed, paraffin-embedded tissue sections Mod Pathol. 1997 Sep; 10(9):927-32. . View in PubMed

Acute myeloid leukemia with t(6;9) (p23;q34): association with myelodysplasia, basophilia, and initial CD34 negative immunophenotype Am J Clin Pathol. 1997 Apr; 107(4):430-7. . View in PubMed

Numerical cytogenetic abnormalities of chromosomes 3, 7, and 12 in marginal zone B-cell lymphomas Mod Pathol. 1996 Oct; 9(10):995-1000. . View in PubMed

Certification and training in molecular pathology Hum Pathol. 1996 Apr; 27(4):430-1. . View in PubMed

Myelodysplasia and acute myeloid leukemia occurring after autologous bone marrow transplantation for lymphoma Leuk Lymphoma. 1996 Feb; 20(5-6):365-72. . View in PubMed

Dendritic cell tumors associated with low-grade B-cell malignanciesReport of three cases. Am J Clin Pathol. 1995 Dec; 104(6):696-701. . View in PubMed

Detection of trisomy 8 by fluorescence in situ hybridization on bone marrow smears from patients with subtle myelodysplastic changes Arch Pathol Lab Med. 1994 Dec; 118(12):1196-200. . View in PubMed

Clonal karyotypic hematopoietic cell abnormalities occurring after autologous bone marrow transplantation for Hodgkin's disease and non-Hodgkin's lymphoma Blood. 1994 Aug 01; 84(3):957-63. . View in PubMed

Detection of the Philadelphia chromosome in paraffin-embedded tissue by fluorescence in situ hybridization Mod Pathol. 1994 Jun; 7(5):565-9. . View in PubMed

Osteitis fibrosa cystica simulating metastatic tumorAn almost-forgotten relationship. Am J Clin Pathol. 1993 Dec; 100(6):697-700. . View in PubMed

Extramedullary myeloid cell tumorsAn immunohistochemical and morphologic study of 28 cases. Am J Surg Pathol. 1993 Oct; 17(10):1011-9. . View in PubMed

Graft versus leukemia effect after transplantation with interleukin-2-activated bone marrowCorrelation with eradication of residual disease. Transplantation. 1993 Jul; 56(1):31-7. . View in PubMed

Terminal acute myelogenous leukemia in a patient with congenital agranulocytosis Am J Hematol. 1993 Jun; 43(2):133-8. . View in PubMed

Chronic lymphoproliferative disorders involving blood and bone marrow Am J Clin Pathol. 1993 Apr; 99(4):494-503. . View in PubMed

Epidemiological and biological study of acquired immunodeficiency syndrome-related lymphoma in the County of Los Angeles: preliminary results Cancer Res. 1992 Oct 01; 52(19 Suppl):5482s-5484s. . View in PubMed

Monocytoid B-cell lymphomas: an assessment of diagnostic criteria and a perspective on histogenesis Hum Pathol. 1992 Sep; 23(9):1061-71. . View in PubMed

Human immunodeficiency virus-related lymphomaPrognostic factors predictive of survival. Cancer. 1991 Dec 01; 68(11):2466-72. . View in PubMed

Bone marrow examination for the diagnosis of mycobacterial and fungal infections in the acquired immunodeficiency syndrome Arch Pathol Lab Med. 1991 Nov; 115(11):1125-32. . View in PubMed

Auer rod-like inclusions in circulating lymphoma cells Am J Clin Pathol. 1991 Jul; 96(1):111-5. . View in PubMed

Hodgkin's disease occurring in monocytoid B-cell clusters Am J Clin Pathol. 1991 Jun; 95(6):802-8. . View in PubMed

Induction of graft versus leukemia effect in bone marrow transplantation: dosage and time schedule dependency of interleukin 2 therapy Cancer Res. 1991 Apr 15; 51(8):2015-20. . View in PubMed

Kaposi's sarcoma in the bone marrow of a patient with AIDS Am J Clin Pathol. 1991 Apr; 95(4):561-4. . View in PubMed

Epstein-Barr virus in benign lymph node biopsies from individuals infected with the human immunodeficiency virus is associated with concurrent or subsequent development of non-Hodgkin's lymphoma Blood. 1991 Apr 01; 77(7):1527-33. . View in PubMed

Anti-BLA36 monoclonal antibody shows reactivity with Hodgkin's cells and B lymphocytes in frozen and paraffin-embedded tissues. Hematol Oncol. 1991 Mar-Apr; 9(2):103-14. . View in PubMed

Bone marrow transplantation with interleukin-2-activated bone marrow followed by interleukin-2 therapy for acute myeloid leukemia in mice Blood. 1990 Dec 01; 76(11):2187-90. . View in PubMed

Kikuchi-Fujimoto disease mimicking malignant lymphoma Am J Surg Pathol. 1990 Jun; 14(6):514-23. . View in PubMed

Detection of specific t(14;18) chromosomal translocations in fixed tissues Hum Pathol. 1990 Feb; 21(2):199-203. . View in PubMed

Human T-cell lymphotropic virus type I (HTLV-I)-associated adult T-cell leukemia-lymphoma in a patient infected with human immunodeficiency virus type 1 (HIV-1) Ann Intern Med. 1989 Dec 01; 111(11):871-5. . View in PubMed

Human immunodeficiency viral DNA is readily found in lymph node biopsies from seropositive individualsAnalysis of fixed tissue using the polymerase chain reaction. Am J Pathol. 1989 Oct; 135(4):697-702. . View in PubMed

Acute myeloid leukemia, FAB M-1 microgranular variant: a multiparameter study Hematol Pathol. 1989; 3(1):11-22. . View in PubMed

Reactive immunoblastic proliferations Semin Diagn Pathol. 1988 Nov; 5(4):317-28. . View in PubMed

Peripheral T-cell lymphoma in a patient with acquired immune deficiency syndrome Cancer. 1988 Mar 01; 61(5):947-51. . View in PubMed

Primary non-Hodgkin's lymphoma of the heart in two patients with the acquired immunodeficiency syndrome Arch Pathol Lab Med. 1987 Mar; 111(3):254-6. . View in PubMed

Immunoglobulin and T cell receptor gene rearrangements in human lymphoma and leukemia Blood. 1987 Jan; 69(1):79-86. . View in PubMed

Percutaneous needle biopsy in the diagnosis and classification of lymphoma Cancer. 1986 Mar 01; 57(5):1074-8. . View in PubMed

Lymphocyte subsets in lymph nodes of homosexual men with generalized unexplained lymphadenopathyCorrelation with morphology and blood changes. Arch Pathol Lab Med. 1985 Feb; 109(2):133-7. . View in PubMed

Plasmacytoma arising in giant lymph node hyperplasia Am J Clin Pathol. 1982 Oct; 78(4):541-4. . View in PubMed

Prolymphocytic leukemia of helper cell phenotype: report of a case and review of the scientific literature Am J Clin Pathol. 1982 May; 77(5):643-7. . View in PubMed

Cycochemical profiles in acute lymphoblastic leukemia Am J Pediatr Hematol Oncol. 1979; 1(3):263-75. . View in PubMed

Bone marrow aspiration and trephine biopsyAn approach to a thorough study. Am J Clin Pathol. 1978 Nov; 70(5):753-9. . View in PubMed

Acute monocytic leukemiaCytologic, histologic, cytochemical, ultrastructural, and cytogenetic observations. Am J Clin Pathol. 1976 Apr; 65(4):471-82. . View in PubMed

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