Saverio Bellusci
TRAIL protects the immature lung from hyperoxic injury Cell Death Dis. 2022 Jul 15; 13(7):614. . View in PubMed
A role for metformin in the treatment of Dupuytren disease? Biomed Pharmacother. 2022 Jun; 150:112930.. View in PubMed
Fgfr2b signaling is essential for the maintenance of the alveolar epithelial type 2 lineage during lung homeostasis in mice Cell Mol Life Sci. 2022 May 19; 79(6):302. . View in PubMed
Hedgehog Signaling Pathway Orchestrates Human Lung Branching Morphogenesis Int J Mol Sci. 2022 May 09; 23(9). . View in PubMed
When inflammation meets lung development-an update on the pathogenesis of bronchopulmonary dysplasia Mol Cell Pediatr. 2022 Apr 20; 9(1):7. . View in PubMed
FGF10 protects against particulate matter (PM)-induced lung injury via regulation of endoplasmic reticulum stress Int Immunopharmacol. 2022 Apr; 105:108552. . View in PubMed
Sphingosine 1-phosphate receptor 1 governs endothelial barrier function and angiogenesis by upregulating endoglin signaling Ann Transl Med. 2022 Feb; 10(3):136. . View in PubMed
Therapeutic induction of Bcl2-associated athanogene 3-mediated autophagy in idiopathic pulmonary fibrosis Clin Transl Med. 2022 07; 12(7):e935. . View in PubMed
Wnt5a Promotes AT1 and Represses AT2 Lineage-Specific Gene Expression in a Cell-Context-Dependent Manner Stem Cells. 2022 07 27; 40(7):691-703. . View in PubMed
Differential LysoTracker Uptake Defines Two Populations of Distal Epithelial Cells in Idiopathic Pulmonary Fibrosis Cells. 2022 01 11; 11(2). . View in PubMed
FGF10 Triggers De Novo Alveologenesis in a Bronchopulmonary Dysplasia Model: Impact on Resident Mesenchymal Niche Cells Stem Cells. 2022 06 22; 40(6):605-617. . View in PubMed
A mesenchymal to epithelial switch in Fgf10 expression specifies an evolutionary-conserved population of ionocytes in salivary glands Cell Rep. 2022 04 12; 39(2):110663. . View in PubMed
Hedgehog-responsive PDGFRa(+) fibroblasts maintain a unique pool of alveolar epithelial progenitor cells during alveologenesis Cell Rep. 2022 04 05; 39(1):110608. . View in PubMed
Cell-Surface Programmed Death Ligand-1 Expression Identifies a Sub-Population of Distal Epithelial Cells Enriched in Idiopathic Pulmonary Fibrosis Cells. 2022 05 10; 11(10). . View in PubMed
Oxygen Toxicity to the Immature Lung-Part I: Pathomechanistic Understanding and Preclinical Perspectives Int J Mol Sci. 2021 Oct 12; 22(20). . View in PubMed
Oxygen Toxicity to the Immature Lung-Part II: The Unmet Clinical Need for Causal Therapy Int J Mol Sci. 2021 Oct 02; 22(19). . View in PubMed
MSC Based Therapies to Prevent or Treat BPD-A Narrative Review on Advances and Ongoing Challenges Int J Mol Sci. 2021 Jan 24; 22(3). . View in PubMed
Characterization in mice of the resident mesenchymal niche maintaining AT2 stem cell proliferation in homeostasis and disease Stem Cells. 2021 10; 39(10):1382-1394. . View in PubMed
Identification of a novel subset of alveolar type 2 cells enriched in PD-L1 and expanded following pneumonectomy Eur Respir J. 2021 10; 58(5). . View in PubMed
Cross-Talk Between Inflammation and Fibroblast Growth Factor 10 During Organogenesis and Pathogenesis: Lessons Learnt From the Lung and Other Organs Front Cell Dev Biol. 2021; 9:656883. . View in PubMed
The Multifunctional Contribution of FGF Signaling to Cardiac Development, Homeostasis, Disease and Repair Front Cell Dev Biol. 2021; 9:672935. . View in PubMed
The effect of long-term doxycycline treatment in a mouse model of cigarette smoke-induced emphysema and pulmonary hypertension Am J Physiol Lung Cell Mol Physiol. 2021 05 01; 320(5):L903-L915. . View in PubMed
Validation of a Novel Fgf10Cre-ERT2 Knock-in Mouse Line Targeting FGF10Pos Cells Postnatally Front Cell Dev Biol. 2021; 9:671841. . View in PubMed
Potential Impact of Diabetes and Obesity on Alveolar Type 2 (AT2)-Lipofibroblast (LIF) Interactions After COVID-19 Infection Front Cell Dev Biol. 2021; 9:676150. . View in PubMed
Evidence for Multiple Origins of De Novo Formed Vascular Smooth Muscle Cells in Pulmonary Hypertension: Challenging the Dominant Model of Pre-Existing Smooth Muscle Expansion Int J Environ Res Public Health. 2021 08 14; 18(16). . View in PubMed
Nat Commun. 2021 02 16; 12(1):1072. . View in PubMed
FGF10 and Lipofibroblasts in Lung Homeostasis and Disease: Insights Gained From the Adipocytes Front Cell Dev Biol. 2021; 9:645400. . View in PubMed
miR-142-3p regulates cortical oligodendrocyte gene co-expression networks associated with tauopathy Hum Mol Genet. 2021 03 25; 30(1):103-118. . View in PubMed
Evidence for lung repair and regeneration in humans: key stem cells and therapeutic functions of fibroblast growth factors Front Med. 2020 Jun; 14(3):262-272. . View in PubMed
MSC Based Therapies-New Perspectives for the Injured Lung J Clin Med. 2020 Mar 03; 9(3). . View in PubMed
Evidence for the critical role of the PI3K signaling pathway in particulate matter-induced dysregulation of the inflammatory mediators COX-2/PGE2 and the associated epithelial barrier protein Filaggrin in the bronchial epithelium Cell Biol Toxicol. 2020 08; 36(4):301-313. . View in PubMed
Use of the Reversible Myogenic to Lipogenic Transdifferentiation Switch for the Design of Pre-clinical Drug Screening in Idiopathic Pulmonary Fibrosis Front Bioeng Biotechnol. 2020; 8:569865. . View in PubMed
Targeting Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension (BPD-PH): Potential Role of the FGF Signaling Pathway in the Development of the Pulmonary Vascular System Cells. 2020 08 11; 9(8). . View in PubMed
p16INK4a and the Alveolar Niche Take Center Stage in Bronchopulmonary Dysplasia Am J Respir Crit Care Med. 2020 10 15; 202(8):1065-1067. . View in PubMed
PDGFRa and aSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis Am J Physiol Lung Cell Mol Physiol. 2020 04 01; 318(4):L684-L697. . View in PubMed
WNT5a-ROR Signaling Is Essential for Alveologenesis Cells. 2020 02 07; 9(2). . View in PubMed
Fgf10/Fgfr2b Signaling in Mammary Gland Development, Homeostasis, and Cancer Front Cell Dev Biol. 2020; 8:415. . View in PubMed
Evidence for Overlapping and Distinct Biological Activities and Transcriptional Targets Triggered by Fibroblast Growth Factor Receptor 2b Signaling between Mid- and Early Pseudoglandular Stages of Mouse Lung Development Cells. 2020 05 21; 9(5). . View in PubMed
Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration Cell Rep. 2020 12 22; 33(12):108549. . View in PubMed
Editorial: The Fibroblast Growth Factor Signaling Pathway in Metabolic Regulation, Development, Disease, and Repair After Injury Front Pharmacol. 2020; 11:586654. . View in PubMed
Corrigendum: An FGFR/AKT/SOX2 Signaling Axis Controls Pancreatic Cancer Stemness Front Cell Dev Biol. 2020; 8:594589. . View in PubMed
Failure to Down-Regulate miR-154 Expression in Early Postnatal Mouse Lung Epithelium Suppresses Alveologenesis, with Changes in Tgf-ß Signaling Similar to those Induced by Exposure to Hyperoxia Cells. 2020 04 02; 9(4). . View in PubMed
An FGFR/AKT/SOX2 Signaling Axis Controls Pancreatic Cancer Stemness Front Cell Dev Biol. 2020; 8:287. . View in PubMed
Fibroblast Growth Factors in the Management of Acute Kidney Injury Following Ischemia-Reperfusion Front Pharmacol. 2020; 11:426. . View in PubMed
Fibroblast growth factor 10 is a negative regulator of postnatal neurogenesis in the mouse hypothalamus Development. 2020 07 13; 147(13). . View in PubMed
Fgf10 Signaling-Based Evidence for the Existence of an Embryonic Stage Distinct From the Pseudoglandular Stage During Mouse Lung Development Front Cell Dev Biol. 2020; 8:576604. . View in PubMed
Fgf10/Fgfr2b Signaling Orchestrates the Symphony of Molecular, Cellular, and Physical Processes Required for Harmonious Airway Branching Morphogenesis Front Cell Dev Biol. 2020; 8:620667. . View in PubMed
Multilineage murine stem cells generate complex organoids to model distal lung development and disease EMBO J. 2020 11 02; 39(21):e103476. . View in PubMed
A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development Cell Mol Life Sci. 2019 Jul; 76(14):2817-2832. . View in PubMed
A functional variant in the miR-142 promoter modulating its expression and conferring risk of Alzheimer disease Hum Mutat. 2019 11; 40(11):2131-2145. . View in PubMed
Characterisation of endogenous players in fibroblast growth factor-regulated functions of hypothalamic tanycytes and energy-balance nuclei J Neuroendocrinol. 2019 08; 31(8):e12750. . View in PubMed
Discordant roles for FGF ligands in lung branching morphogenesis between human and mouse J Pathol. 2019 02; 247(2):254-265. . View in PubMed
Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis Nat Commun. 2019 05 20; 10(1):2229. . View in PubMed
Imaging and Analysis of Mouse Embryonic Whole Lung, Isolated Tissue, and Lineage-Labelled Cell Culture Methods Mol Biol. 2019; 1940:109-127. . View in PubMed
Characterization of Tg(Etv4-GFP) and Etv5RFP Reporter Lines in the Context of Fibroblast Growth Factor 10 Signaling During Mouse Embryonic Lung Development Front Genet. 2019; 10:178. . View in PubMed
Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis Nat Commun. 2019 07 05; 10(1):2987. . View in PubMed
Impact of Fgf10 deficiency on pulmonary vasculature formation in a mouse model of bronchopulmonary dysplasia Hum Mol Genet. 2019 05 01; 28(9):1429-1444. . View in PubMed
FGF10-FGFR2B Signaling Generates Basal Cells and Drives Alveolar Epithelial Regeneration by Bronchial Epithelial Stem Cells after Lung Injury Stem Cell Reports. 2019 05 14; 12(5):1041-1055. . View in PubMed
Normal lung development needs self-eating J Clin Invest. 2019 06 04; 129(7):2658-2659. . View in PubMed
The Long Noncoding RNA DNM3OS Is a Reservoir of FibromiRs with Major Functions in Lung Fibroblast Response to TGF-ß and Pulmonary Fibrosis Am J Respir Crit Care Med. 2019 07 15; 200(2):184-198. . View in PubMed
Secondary crest myofibroblast PDGFRa controls the elastogenesis pathway via a secondary tier of signaling networks during alveologenesis Development. 2019 08 09; 146(15). . View in PubMed
miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes Nat Commun. 2019 12 13; 10(1):5697. . View in PubMed
Role of FGF10/FGFR2b Signaling in Mouse Digestive Tract Development, Repair and Regeneration Following Injury Front Cell Dev Biol. 2019; 7:326. . View in PubMed
Use of three-dimensional organoids and lung-on-a-chip methods to study lung development, regeneration and disease Eur Respir J. 2018 11; 52(5). . View in PubMed
Resident alveolar macrophages are master regulators of arrested alveolarization in experimental bronchopulmonary dysplasia J Pathol. 2018 06; 245(2):153-159. . View in PubMed
Low density lipoprotein receptor-related protein 1 couples ß1 integrin activation to degradation Cell Mol Life Sci. 2018 05; 75(9):1671-1685. . View in PubMed
Resident cell lineages are preserved in pulmonary vascular remodeling J Pathol. 2018 04; 244(4):485-498. . View in PubMed
Neonatal exposure to hyperoxia leads to persistent disturbances in pulmonary histone signatures associated with NOS3 and STAT3 in a mouse model Clin Epigenetics. 2018; 10:37. . View in PubMed
A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis Front Genet. 2018; 9:746. . View in PubMed
The Potentials and Caveats of Mesenchymal Stromal Cell-Based Therapies in the Preterm Infant Stem Cells Int. 2018; 2018:9652897. . View in PubMed
Human lung branching morphogenesis is orchestrated by the spatiotemporal distribution of ACTA2, SOX2, and SOX9 Am J Physiol Lung Cell Mol Physiol. 2018 01 01; 314(1):L144-L149. . View in PubMed
miR-142-3p is associated with aberrant WNT signaling during airway remodeling in asthma Am J Physiol Lung Cell Mol Physiol. 2018 08 01; 315(2):L328-L333. . View in PubMed
Role of Fibroblast Growth Factor 10 in Mesenchymal Cell Differentiation During Lung Development and Disease Front Genet. 2018; 9:545. . View in PubMed
2018 08 01; 315(2):L248-L252. . View in PubMed
Am J Physiol Lung Cell Mol Physiol. 2018 07 01; 315(1):L87-L101. . View in PubMed
Fibroblast Growth Factor 10 and Vertebrate Limb Development Front Genet. 2018; 9:705. . View in PubMed
Fibroblast growth factor 2 protects against renal ischaemia/reperfusion injury by attenuating mitochondrial damage and proinflammatory signalling J Cell Mol Med. 2017 Nov; 21(11):2909-2925. . View in PubMed
Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany27-28 October 2016. Mol Cell Pediatr. 2017 May; 4(Suppl 1):5. . View in PubMed
A novel mouse Cre-driver line targeting Perilipin 2-expressing cells in the neonatal lung Genesis. 2017 12; 55(12). . View in PubMed
Ex vivo analysis of the contribution of FGF10+ cells to airway smooth muscle cell formation during early lung development Dev Dyn. 2017 07; 246(7):531-538. . View in PubMed
Origin and characterization of alpha smooth muscle actin-positive cells during murine lung development Stem Cells. 2017 06; 35(6):1566-1578. . View in PubMed
Therapeutic and pathological roles of fibroblast growth factors in pulmonary diseases Dev Dyn. 2017 04; 246(4):235-244. . View in PubMed
MicroRNA-142 is a multifaceted regulator in organogenesis, homeostasis, and disease Dev Dyn. 2017 04; 246(4):285-290. . View in PubMed
Mesenchymal Stem Cells in Fibrotic Disease Cell Stem Cell. 2017 08 03; 21(2):166-177. . View in PubMed
Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung FibrosisCell Stem Cell. 2017 02 02; 20(2):261-273. e3. . View in PubMed
Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis Cell Stem Cell. 2017 04 06; 20(4):571. . View in PubMed
Fgf10 deficiency is causative for lethality in a mouse model of bronchopulmonary dysplasia J Pathol. 2017 Jan; 241(1):91-103. . View in PubMed
Retraction: Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epitheliumDevelopment doi: 10. 1242/dev. 058479. Development. 2017 10 15; 144(20):3849. . View in PubMed
Fgf10-Hippo Epithelial-Mesenchymal Crosstalk Maintains and Recruits Lung Basal Stem CellsDev Cell. 2017 10 09; 43(1):48-59. e5. . View in PubMed
Pathogenesis of bronchopulmonary dysplasia: when inflammation meets organ development Mol Cell Pediatr. 2016 Dec; 3(1):23. . View in PubMed
Alveologenesis: key cellular players and fibroblast growth factor 10 signaling Mol Cell Pediatr. 2016 Dec; 3(1):17. . View in PubMed
Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate BMC Biol. 2016 Mar 16; 14:19. . View in PubMed
MAP1LC3B overexpression protects against Hermansky-Pudlak syndrome type-1-induced defective autophagy in vitro Am J Physiol Lung Cell Mol Physiol. 2016 Mar 15; 310(6):L519-31. . View in PubMed
Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate EMBO Mol Med. 2016 12; 8(12):1380-1389. . View in PubMed
Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair PLoS Pathog. 2016 06; 12(6):e1005544. . View in PubMed
Role of fibroblast growth factors in organ regeneration and repair Semin Cell Dev Biol. 2016 05; 53:76-84. . View in PubMed
Hematopoietic and Mesenchymal Stem Cells in Biomedical and Clinical Applications Stem Cells Int. 2016; 2016:3157365. . View in PubMed
Evidence for the involvement of fibroblast growth factor 10 in lipofibroblast formation during embryonic lung development Development. 2015 Dec 01; 142(23):4139-50. . View in PubMed
Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis Thorax. 2015 Nov; 70(11):1022-32. . View in PubMed
Characterization of the platelet-derived growth factor receptor-a-positive cell lineage during murine late lung development Am J Physiol Lung Cell Mol Physiol. 2015 Nov 01; 309(9):L942-58. . View in PubMed
Non-canonical WNT signalling in the lung J Biochem. 2015 Nov; 158(5):355-65. . View in PubMed
Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis Respir Res. 2015 Jul 03; 16:83. . View in PubMed
High mobility group protein-mediated transcription requires DNA damage marker? -H2AX. Cell Res. 2015 Jul; 25(7):837-50.. View in PubMed
Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development BMC Biol. 2015 Jun 20; 13:42. . View in PubMed
Attenuating endogenous Fgfr2b ligands during bleomycin-induced lung fibrosis does not compromise murine lung repair Am J Physiol Lung Cell Mol Physiol. 2015 May 15; 308(10):L1014-24. . View in PubMed
Fibroblast growth factor 10 alters the balance between goblet and Paneth cells in the adult mouse small intestine Am J Physiol Gastrointest Liver Physiol. 2015 Apr 15; 308(8):G678-90. . View in PubMed
Validation of Tuba1a as appropriate internal control for normalization of gene expression analysis during mouse lung development Int J Mol Sci. 2015 Feb 25; 16(3):4492-511. . View in PubMed
Pharmacological application of growth factors: basic and clinical Biomed Res Int. 2015; 2015:141794. . View in PubMed
A breath of fresh air on the mesenchyme: impact of impaired mesenchymal development on the pathogenesis of bronchopulmonary dysplasia Front Med (Lausanne). 2015; 2:27. . View in PubMed
Generation and Validation of miR-142 Knock Out Mice PLoS One. 2015; 10(9):e0136913. . View in PubMed
CCL27: Novel Cytokine with Potential Role in Pathogenesis of Multiple Sclerosis Biomed Res Int. 2015; 2015:189638. . View in PubMed
FGF10 promotes regional foetal cardiomyocyte proliferation and adult cardiomyocyte cell-cycle re-entry Cardiovasc Res. 2014 Dec 01; 104(3):432-42. . View in PubMed
Regulation of induced pluripotent stem (iPS) cell induction by Wnt/ß-catenin signaling J Biol Chem. 2014 Mar 28; 289(13):9221-32. . View in PubMed
Hmga2 is required for canonical WNT signaling during lung development BMC Biol. 2014 Mar 24; 12:21. . View in PubMed
miR-142-3p balances proliferation and differentiation of mesenchymal cells during lung development Development. 2014 Mar; 141(6):1272-81. . View in PubMed
Fgf10-positive cells represent a progenitor cell population during lung development and postnatally Development. 2014 Jan; 141(2):296-306. . View in PubMed
Walking along the Fibroblast Growth Factor 10 Route: A Key Pathway to Understand the Control and Regulation of Epithelial and Mesenchymal Cell-Lineage Formation during Lung Development and Repair after Injury Scientifica (Cairo). 2014; 2014:538379. . View in PubMed
Quantitative proteome analysis of alveolar type-II cells reveals a connection of integrin receptor subunits beta 2/6 and WNT signaling J Proteome Res. 2013 Dec 06; 12(12):5598-608. . View in PubMed
Functional proteomics defines the molecular switch underlying FGF receptor trafficking and cellular outputs Mol Cell. 2013 Sep 26; 51(6):707-22. . View in PubMed
Fgf10-expressing tanycytes add new neurons to the appetite/energy-balance regulating centers of the postnatal and adult hypothalamus J Neurosci. 2013 Apr 03; 33(14):6170-80. . View in PubMed
Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease Thorax. 2013 Apr; 68(4):380-4. . View in PubMed
FGF10 Signaling Enhances Epicardial Cell Expansion during Neonatal Mouse Heart Repair J Cardiovasc Dis Diagn. 2013 Mar; 1(1). . View in PubMed
The anti-scar effects of basic fibroblast growth factor on the wound repair in vitro and in vivo PLoS One. 2013; 8(4):e59966. . View in PubMed
Transient Inhibition of FGFR2b-ligands signaling leads to irreversible loss of cellular ß-catenin organization and signaling in AER during mouse limb development PLoS One. 2013; 8(10):e76248. . View in PubMed
Mesodermal Pten inactivation leads to alveolar capillary dysplasia- like phenotype J Clin Invest. 2012 Nov; 122(11):3862-72. . View in PubMed
FGF9-Pitx2-FGF10 signaling controls cecal formation in mice Dev Biol. 2012 Sep 15; 369(2):340-8. . View in PubMed
Embryonic epithelial Pten deletion through Nkx21-cre leads to thyroid tumorigenesis in a strain-dependent manner. Endocr Relat Cancer. 2012 Apr; 19(2):111-122. . View in PubMed
Effects of maternal food restriction on offspring lung extracellular matrix deposition and long term pulmonary function in an experimental rat model Pediatr Pulmonol. 2012 Feb; 47(2):162-71. . View in PubMed
Characterization of a novel fibroblast growth factor 10 (Fgf10) knock-in mouse line to target mesenchymal progenitors during embryonic development PLoS One. 2012; 7(6):e38452. . View in PubMed
Fibroblast growth factor 10-fibroblast growth factor receptor 2b mediated signaling is not required for adult glandular stomach homeostasis PLoS One. 2012; 7(11):e49127. . View in PubMed
Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury J Clin Invest. 2011 Nov; 121(11):4409-19. . View in PubMed
Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung Dev Biol. 2011 May 15; 353(2):242-58. . View in PubMed
Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium Development. 2011 Apr; 138(7):1395-407. . View in PubMed
Eyes absent 1 (Eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung Dev Biol. 2011 Feb 01; 350(1):112-26. . View in PubMed
FGF10 controls the patterning of the tracheal cartilage rings via Shh Development. 2011 Jan; 138(2):273-82. . View in PubMed
Ectodermal influx and cell hypertrophy provide early growth for all murine mammary rudiments, and are differentially regulated among them by Gli3 PLoS One. 2011; 6(10):e26242. . View in PubMed
Contrasting expression of canonical Wnt signaling reporters TOPGAL, BATGAL and Axin2(LacZ) during murine lung development and repair PLoS One. 2011; 6(8):e23139. . View in PubMed
Signaling by FGFR2b controls the regenerative capacity of adult mouse incisors Development. 2010 Nov; 137(22):3743-52. . View in PubMed
Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation Hum Mol Genet. 2010 Sep 01; 19(17):3457-67. . View in PubMed
Epithelial stress and apoptosis underlie Hermansky-Pudlak syndrome-associated interstitial pneumonia Am J Respir Crit Care Med. 2010 Jul 15; 182(2):207-19. . View in PubMed
Signaling via Alk5 controls the ontogeny of lung Clara cells Development. 2010 Mar; 137(5):825-33. . View in PubMed
Lung organogenesis Curr Top Dev Biol. 2010; 90:73-158. . View in PubMed
Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury Am J Respir Crit Care Med. 2009 Oct 15; 180(8):701-12. . View in PubMed
Wnt5a knock-out mouse as a new model of anorectal malformation J Surg Res. 2009 Oct; 156(2):278-82. . View in PubMed
Fibroblast growth factor 10 plays a causative role in the tracheal cartilage defects in a mouse model of Apert syndrome Pediatr Res. 2009 Oct; 66(4):386-90. . View in PubMed
miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution Dev Biol. 2009 Sep 15; 333(2):238-50. . View in PubMed
Overexpression of fibroblast growth factor-10 during both inflammatory and fibrotic phases attenuates bleomycin-induced pulmonary fibrosis in mice Am J Respir Crit Care Med. 2009 Sep 01; 180(5):424-36. . View in PubMed
Induction of fibroblast growth factor 10 (FGF10) in the ileal crypt epithelium after massive small bowel resection suggests a role for FGF10 in gut adaptation Dev Dyn. 2009 Feb; 238(2):294-301. . View in PubMed
Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages Stem Cells. 2008 Nov; 26(11):2902-11. . View in PubMed
Mechanisms of TGFbeta inhibition of LUNG endodermal morphogenesis: the role of TbetaRII, Smads, Nkx21 and Pten. Dev Biol. 2008 Aug 15; 320(2):340-50. . View in PubMed
Stem/progenitor cells in lung development, injury repair, and regeneration Proc Am Thorac Soc. 2008 Aug 15; 5(6):703-6. . View in PubMed
Lung stem cells in the balance Nat Genet. 2008 Jul; 40(7):822-4. . View in PubMed
Localization and fate of Fgf10-expressing cells in the adult mouse brain implicate Fgf10 in control of neurogenesis Mol Cell Neurosci. 2008 Apr; 37(4):857-68. . View in PubMed
Tracheal occlusion increases the rate of epithelial branching of embryonic mouse lung via the FGF10-FGFR2b-Sprouty2 pathway Mech Dev. 2008 Mar-Apr; 125(3-4):314-24. . View in PubMed
SMAD3 prevents binding of NKX21 and FOXA1 to the SpB promoter through its MH1 and MH2 domains. Nucleic Acids Res. 2008 Jan; 36(1):179-88. . View in PubMed
Fibroblast growth factor 10 is critical for liver growth during embryogenesis and controls hepatoblast survival via beta-catenin activation Hepatology. 2007 Oct; 46(4):1187-97. . View in PubMed
Sprouty2 downregulation plays a pivotal role in mediating crosstalk between TGF-beta1 signaling and EGF as well as FGF receptor tyrosine kinase-ERK pathways in mesenchymal cells J Cell Physiol. 2007 Sep; 212(3):796-806. . View in PubMed
Lung development and adult lung diseases Chest. 2007 Aug; 132(2):651-6. . View in PubMed
TNF-alpha represses transcription of human Bone Morphogenetic Protein-4 in lung epithelial cells Gene. 2007 May 15; 393(1-2):70-80. . View in PubMed
Fibroblast growth factor 10 is required for survival and proliferation but not differentiation of intestinal epithelial progenitor cells during murine colon development Dev Biol. 2006 Nov 15; 299(2):373-85. . View in PubMed
Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung Dev Biol. 2006 Nov 01; 299(1):52-62. . View in PubMed
Lung development and susceptibility to chronic obstructive pulmonary disease Proc Am Thorac Soc. 2006 Nov; 3(8):668-72. . View in PubMed
Gli3-mediated somitic Fgf10 expression gradients are required for the induction and patterning of mammary epithelium along the embryonic axes Development. 2006 Jun; 133(12):2325-35. . View in PubMed
Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling Gastroenterology. 2006 Apr; 130(4):1233-44. . View in PubMed
The fibroblast growth factor pathway serves a regulatory role in proliferation and apoptosis in the pathogenesis of intestinal atresia J Pediatr Surg. 2006 Jan; 41(1):132-6; discussion 132-6. . View in PubMed
Wnt5a regulates Shh and Fgf10 signaling during lung development Dev Biol. 2005 Nov 01; 287(1):86-97. . View in PubMed
FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis BMC Dev Biol. 2005 Jun 22; 5:11. . View in PubMed
A novel function for the protein tyrosine phosphatase Shp2 during lung branching morphogenesis Dev Biol. 2005 Jun 15; 282(2):422-31. . View in PubMed
Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage Development. 2005 May; 132(9):2157-66. . View in PubMed
Molecular mechanisms of early lung specification and branching morphogenesis Pediatr Res. 2005 May; 57(5 Pt 2):26R-37R. . View in PubMed
Protein interaction mapping: a Drosophila case study Genome Res. 2005 Mar; 15(3):376-84. . View in PubMed
Fibroblast growth factor-10 serves a regulatory role in duodenal development J Pediatr Surg. 2005 Feb; 40(2):313-6. . View in PubMed
Colonic atresia without mesenteric vascular occlusionThe role of the fibroblast growth factor 10 signaling pathway. J Pediatr Surg. 2005 Feb; 40(2):390-6. . View in PubMed
Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung Dev Biol. 2005 Jan 15; 277(2):316-31. . View in PubMed
Genomic structure and promoter characterization of the human Sprouty4 gene, a novel regulator of lung morphogenesis Am J Physiol Lung Cell Mol Physiol. 2004 Jul; 287(1):L52-9. . View in PubMed
Fibroblast growth factor receptor 2 IIIb invalidation--a potential cause of familial duodenal atresia J Pediatr Surg. 2004 Jun; 39(6):872-4. . View in PubMed
Fibroblast growth factor 10 (Fgf10) invalidation results in anorectal malformation in mice J Pediatr Surg. 2004 Mar; 39(3):360-5; discussion 360-5. . View in PubMed
Identification of the mammary line in mouse by Wnt10b expression Dev Dyn. 2004 Feb; 229(2):349-56. . View in PubMed
The molecular genetics of lung morphogenesis and injury repair Paediatr Respir Rev. 2004; 5 Suppl A:S283-7. . View in PubMed
Functional analysis of the human Sprouty2 gene promoter Gene. 2003 Dec 11; 322:175-85. . View in PubMed
Mouse embryonic mammogenesis as a model for the molecular regulation of pattern formation Differentiation. 2003 Jan; 71(1):1-17. . View in PubMed
Growth factor signaling in lung morphogenetic centers: automaticity, stereotypy and symmetry Respir Res. 2003; 4:5. . View in PubMed
Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo Development. 2002 Jan; 129(1):53-60. . View in PubMed
