Dr. Xiong earned his medical degree from Bengbu Medical College. He stayed on to perform his internship and residency in pathology. Dr. Xiong then completed his Master's in Pathology from Anhui Medical University, followed by his PhD in Oncology from Peking Union Medical College. He also completed two pathology fellowships.
53rd Annual Meeting of the American Association for the Study of Liver Diseases: Outstanding Research Award, 2002
Cooley's Anemia Foundation: Research Fellowship, 2001-2002
Cooley's Anemia Foundation: Research Fellowship, 2000-2001
Irish National Foundation for Children Research: Senior Research Fellowship, 1996-1998
A Phase II Trial of AEZS-108 in Castration- and Taxane-Resistant Prostate Cancer Clin Genitourin Cancer. 2017 Dec; 15(6):742-749. . View in PubMed
A Phase II Trial of AEZS-108 in Castration- and Taxane-Resistant Prostate Cancer Clin Genitourin Cancer. 2017 12; 15(6):742-749. . View in PubMed
Effects of luteinizing hormone receptor signaling in prostate cancer cells Prostate. 2015 Feb; 75(2):141-50. . View in PubMed
Efficacy of oxaliplatin plus pemetrexed in chemotherapy pretreated metastatic castration-resistant prostate cancer Clin Genitourin Cancer. 2013 Dec; 11(4):416-22. . View in PubMed
Ethnic differences in neuroendocrine expression in prostate cancer tissue Anticancer Res. 2011 Nov; 31(11):3897-901. . View in PubMed
Effect of luteinizing hormone on the steroidogenic pathway in prostate cancer Prostate. 2011 Jun 01; 71(8):892-8. . View in PubMed
A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis Cancer Res. 2011 Apr 15; 71(8):2848-57. . View in PubMed
The relationship between proangiogenic gene expression levels in prostate cancer and their prognostic value for clinical outcomes Prostate. 2010 Nov 01; 70(15):1692-700. . View in PubMed
Expression of receptors for luteinizing hormone-releasing hormone (LH-RH) in prostate cancers following therapy with LH-RH agonists Clin Cancer Res. 2010 Sep 15; 16(18):4675-80. . View in PubMed
Gene profiling and pathway analysis of neuroendocrine transdifferentiated prostate cancer cells Prostate. 2009 Jan 01; 69(1):12-23. . View in PubMed
Hepatic macrophage iron aggravates experimental alcoholic steatohepatitis Am J Physiol Gastrointest Liver Physiol. 2008 Sep; 295(3):G512-21. . View in PubMed
Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development Cancer Res. 2008 Jan 15; 68(2):498-505. . View in PubMed
Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis Am J Physiol Gastrointest Liver Physiol. 2008 Jan; 294(1):G39-49. . View in PubMed
Iron causes interactions of TAK1, p21ras, and phosphatidylinositol 3-kinase in caveolae to activate IkappaB kinase in hepatic macrophages J Biol Chem. 2007 Feb 23; 282(8):5582-8. . View in PubMed
Peroxisome proliferator-activated receptor gamma suppresses proximal alpha1(I) collagen promoter via inhibition of p300-facilitated NF-I binding to DNA in hepatic stellate cells J Biol Chem. 2005 Dec 09; 280(49):40650-9. . View in PubMed
Steatohepatitis induced by intragastric overfeeding in mice Hepatology. 2005 Oct; 42(4):905-14. . View in PubMed
Hepatoprotective mechanisms of Yan-gan-wan Hepatol Res. 2005 Aug; 32(4):202-12. . View in PubMed
Adipogenic transcriptional regulation of hepatic stellate cells J Biol Chem. 2005 Feb 11; 280(6):4959-67. . View in PubMed
Inhibition of lipopolysaccharide-stimulated TNF-alpha promoter activity by S-adenosylmethionine and 5'-methylthioadenosine Am J Physiol Gastrointest Liver Physiol. 2004 Aug; 287(2):G352-62. . View in PubMed
Tumor necrosis factor-alpha inhibits peroxisome proliferator-activated receptor gamma activity at a posttranslational level in hepatic stellate cells Am J Physiol Gastrointest Liver Physiol. 2004 May; 286(5):G722-9. . View in PubMed
Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells J Biol Chem. 2004 Mar 19; 279(12):11392-401. . View in PubMed
Essential role of matrix metalloproteinases in interleukin-1-induced myofibroblastic activation of hepatic stellate cell in collagen J Biol Chem. 2004 Feb 06; 279(6):4820-8. . View in PubMed
Signaling role of iron in NF-kappa B activation in hepatic macrophages Comp Hepatol. 2004 Jan 14; 3 Suppl 1:S36. . View in PubMed
Iron-dependent activation of NF-kappaB in Kupffer cells: a priming mechanism for alcoholic liver disease Alcohol. 2003 Jun; 30(2):107-13. . View in PubMed
Signaling role of intracellular iron in NF-kappaB activation J Biol Chem. 2003 May 16; 278(20):17646-54. . View in PubMed
Iron activates NF-kappaB in Kupffer cells Am J Physiol Gastrointest Liver Physiol. 2002 Sep; 283(3):G719-26. . View in PubMed
IL-10 receptor and coreceptor expression in quiescent and activated hepatic stellate cells Am J Physiol Gastrointest Liver Physiol. 2002 Jun; 282(6):G981-90. . View in PubMed