Keck School Faculty

Thomas G Keens, MD
Thomas G Keens, MD
Professor of Pediatrics
Pediatrics
CHL Mail Stop 83 Off Campus Los Angeles
An expert on respiratory and pulmonary disorders in children, including sudden infant death syndrome

Adult With PHOX2B Mutation and Late-Onset Congenital Central Hypoventilation Syndrome J Clin Sleep Med. 2018 Dec 15; 14(12):2079-2081. . View in PubMed

Upper Airway Narrowing during Central Apnea in Obese Adolescents Ann Am Thorac Soc. 2018 Dec; 15(12):1465-1471. . View in PubMed

Adult With PHOX2B Mutation and Late-Onset Congenital Central Hypoventilation Syndrome J Clin Sleep Med. 2018 Nov 29. . View in PubMed

Abnormalities in autonomic function in obese boys at-risk for insulin resistance and obstructive sleep apnea Pediatr Res. 2018 Nov 12. . View in PubMed

Sleep in Infants Am J Respir Crit Care Med. 2018 Oct 15; 198(8):P15-P16. . View in PubMed

Congenital central hypoventilation syndrome: diagnosis and management Expert Rev Respir Med. 2018 Apr; 12(4):283-292. . View in PubMed

Obstructive Sleep Apnea in Patients With Congenital Central Hypoventilation Syndrome Ventilated by Diaphragm Pacing Without Tracheostomy J Clin Sleep Med. 2018 Feb 15; 14(2):261-264. . View in PubMed

Congenital central hypoventilation syndrome: diagnosis and management Expert Rev Respir Med. 2018 04; 12(4):283-292. . View in PubMed

The genetics of congenital central hypoventilation syndrome: clinical implications Appl Clin Genet. 2018; 11:135-144. . View in PubMed

Three-Generation Family With Congenital Central Hypoventilation Syndrome and Novel PHOX2B Gene Non-Polyalanine Repeat Mutation J Clin Sleep Med. 2017 Jul 15; 13(7):925-927. . View in PubMed

A System Analysis of Delay in Outpatient Respiratory Equipment Delivery Care Manag J. 2016 Dec 01; 17(4):161-169. . View in PubMed

Phenotypes of California CF Newborn Screen-Positive Children with CFTR 5T Allele by TG Repeat Length Genet Test Mol Biomarkers. 2016 Sep; 20(9):496-503. . View in PubMed

Children and Young Adults Who Received Tracheostomies or Were Initiated on Long-Term Ventilation in PICUs Pediatr Crit Care Med. 2016 Aug; 17(8):e324-34. . View in PubMed

PATIENT EDUCATION | INFORMATION SERIESDiaphragm Pacing by Phrenic Nerve Stimulation. Am J Respir Crit Care Med. 2016 Apr 15; 193(8):P13-4. . View in PubMed

Children and Young Adults Who Received Tracheostomies or Were Initiated on Long-Term Ventilation in PICUs Pediatr Crit Care Med. 2016 08; 17(8):e324-34. . View in PubMed

Forensic Sci Med Pathol. 2016 06; 12(2):229-31. . View in PubMed

Supporting SIDS Families: The Public Health Nurse SIDS Home Visit Public Health Nurs. 2016 05; 33(3):242-8. . View in PubMed

Benign and Deleterious Cystic Fibrosis Transmembrane Conductance Regulator Mutations Identified by Sequencing in Positive Cystic Fibrosis Newborn Screen Children from California PLoS One. 2016; 11(5):e0155624. . View in PubMed

Congenital central hypoventilation syndrome: diagnostic and management challenges Pediatric Health Med Ther. 2016; 7:99-107. . View in PubMed

Benign outcome among positive cystic fibrosis newborn screen children with non-CF-causing variants J Cyst Fibros. 2015 Nov; 14(6):714-9. . View in PubMed

Pilot Feasibility Study of Comprehensive Pulmonary Evaluation Following Lung Radiation Therapy J Pediatr Hematol Oncol. 2015 Oct; 37(7):e412-8. . View in PubMed

Body Fat Composition: A Predictive Factor for Sleep Related Breathing Disorder in Obese Children J Clin Sleep Med. 2015 Sep 15; 11(9):1039-45. . View in PubMed

A physician survey reveals differences in management of idiopathic pulmonary hemosiderosis Orphanet J Rare Dis. 2015 Aug 20; 10:98. . View in PubMed

Examining pediatric emergency home ventilation practices in home health nurses: Opportunities for improved care Pediatr Pulmonol. 2015 Jul; 50(7):691-7. . View in PubMed

Correlation of pulmonary function abnormalities with dose volume histograms in children treated with lung irradiation Pediatr Pulmonol. 2015 Jun; 50(6):596-603. . View in PubMed

Diaphragm Pacing without Tracheostomy in Congenital Central Hypoventilation Syndrome Patients Respiration. 2015; 89(6):534-8. . View in PubMed

Thoracoscopic placement of phrenic nerve pacers for diaphragm pacing in congenital central hypoventilation syndrome J Pediatr Surg. 2015 Jan; 50(1):78-81. . View in PubMed

Pulmonary function abnormalities in childhood cancer survivors treated with bleomycin Pediatr Blood Cancer. 2014 Sep; 61(9):1679-84. . View in PubMed

Pulmonary outcomes in patients with Hodgkin lymphoma treated with involved field radiation Pediatr Blood Cancer. 2014 Jul; 61(7):1277-81. . View in PubMed

Correlation of clinical and dosimetric factors with adverse pulmonary outcomes in children after lung irradiation Int J Radiat Oncol Biol Phys. 2013 Aug 01; 86(5):942-8. . View in PubMed

Exercise performance in thalassemia major: correlation with cardiac iron burden Am J Hematol. 2013 Mar; 88(3):193-7. . View in PubMed

Effect of residential proximity to major roadways on cystic fibrosis exacerbations Int J Environ Health Res. 2013; 23(2):119-31. . View in PubMed

Peripheral chemoreceptors in congenital central hypoventilation syndrome Respir Physiol Neurobiol. 2013 Jan 01; 185(1):186-93. . View in PubMed

Neurocognitive functioning in children with obstructive sleep apnea syndrome: a pilot study of positive airway pressure therapy J Pediatr Nurs. 2012 Dec; 27(6):607-13. . View in PubMed

Sleep fragmentation and intermittent hypoxemia are associated with decreased insulin sensitivity in obese adolescent Latino males Pediatr Res. 2012 Sep; 72(3):293-8. . View in PubMed

Hospital readmissions for newly discharged pediatric home mechanical ventilation patients Pediatr Pulmonol. 2012 Apr; 47(4):409-14. . View in PubMed

End-of-life discussions and advance care planning for children on long-term assisted ventilation with life-limiting conditions J Palliat Care. 2012; 28(1):21-7. . View in PubMed

Pulmonary function in thalassaemia major and its correlation with body iron stores Br J Haematol. 2011 Oct; 155(1):102-5. . View in PubMed

Peripheral vasoconstriction and abnormal parasympathetic response to sighs and transient hypoxia in sickle cell disease Am J Respir Crit Care Med. 2011 Aug 15; 184(4):474-81. . View in PubMed

Costs of hospitalized ventilator-dependent children: differences between a ventilator ward and intensive care unit Pediatr Pulmonol. 2011 Apr; 46(4):356-61. . View in PubMed

Outcomes and causes of death in children on home mechanical ventilation via tracheostomy: an institutional and literature reviewJ Pediatr. 2010 Dec; 157(6):955-959. e2. . View in PubMed

Children with corrected or palliated congenital heart disease on home mechanical ventilation Pediatr Pulmonol. 2010 Jul; 45(7):645-9. . View in PubMed

An official ATS clinical policy statement: Congenital central hypoventilation syndrome: genetic basis, diagnosis, and management Am J Respir Crit Care Med. 2010 Mar 15; 181(6):626-44. . View in PubMed

How much do primary care givers know about tracheostomy and home ventilator emergency care? Pediatr Pulmonol. 2010 Mar; 45(3):270-4.. View in PubMed

Postdoctoral fellowship training in pediatric pulmonology in the United States of America Paediatr Respir Rev. 2010 Mar; 11(1):66-7. . View in PubMed

Does the 6-min walk test correlate with the exercise stress test in children? Pediatr Pulmonol. 2010 Feb; 45(2):135-40.. View in PubMed

Do sequential chest radiographs prompt changes in therapy for home mechanical ventilation children admitted for pneumonia? Care Manag J. 2010; 11(4):217-9.. View in PubMed

Model-based assessment of cardiovascular autonomic control in children with obstructive sleep apnea Sleep. 2009 Jul; 32(7):927-38. . View in PubMed

Congenital hypoventilation syndromes Semin Respir Crit Care Med. 2009 Jun; 30(3):339-47. . View in PubMed

Sudden infant death syndrome: changing epidemiologic patterns in California 1989-2004 J Pediatr. 2008 Oct; 153(4):498-502. . View in PubMed

Supine sleeping position does not cause clinical aspiration in neonates in hospital newborn nurseries Arch Pediatr Adolesc Med. 2007 May; 161(5):507-10. . View in PubMed

Do all infants with apparent life-threatening events need to be admitted? Pediatrics. 2007 Apr; 119(4):679-83.. View in PubMed

Alcohol use in congenital central hypoventilation syndrome Pediatr Pulmonol. 2006 Mar; 41(3):283-5. . View in PubMed

Preoperative predictors of prolonged postoperative mechanical ventilation in children following scoliosis repair Pediatr Pulmonol. 2005 Nov; 40(5):414-9. . View in PubMed

Diaphragm pacers as a treatment for congenital central hypoventilation syndrome Expert Rev Med Devices. 2005 Sep; 2(5):577-85. . View in PubMed

Neuroanatomic deficits in congenital central hypoventilation syndrome J Comp Neurol. 2005 Jul 11; 487(4):361-71. . View in PubMed

Disordered respiratory control in children with partial cerebellar resections Pediatr Pulmonol. 2005 Jul; 40(1):88-91. . View in PubMed

Aberrant neural responses to cold pressor challenges in congenital central hypoventilation syndrome Pediatr Res. 2005 Apr; 57(4):500-9. . View in PubMed

FMRI responses to hyperoxia in congenital central hypoventilation syndrome Pediatr Res. 2005 Apr; 57(4):510-8. . View in PubMed

Noninvasive assessment of cardiovascular autonomic control in pediatric obstructive sleep apnea syndrome Conf Proc IEEE Eng Med Biol Soc. 2005; 1:776-9. . View in PubMed

Noninvasive assessment of cardiovascular autonomic control in pediatric obstructive sleep apnea syndrome Conf Proc IEEE Eng Med Biol Soc. 2005; 4:4416-9. . View in PubMed

Cardio-respiratory Uncoupling in Congenital Central Hypoventilation Syndrome Conf Proc IEEE Eng Med Biol Soc. 2005; 4:4412-5. . View in PubMed

Long-term pulmonary sequelae in children who were treated with extracorporeal membrane oxygenation for neonatal respiratory failure Pediatrics. 2004 Nov; 114(5):1292-6. . View in PubMed

Congenital central hypoventilation syndrome: not just another rare disorder Paediatr Respir Rev. 2004 Sep; 5(3):182-9. . View in PubMed

Preoperative polysomnograms and infant pulmonary function tests do not predict prolonged postoperative mechanical ventilation in children following scoliosis repair Pediatr Pulmonol. 2004 Sep; 38(3):256-60. . View in PubMed

Sudden infant death syndrome and unclassified sudden infant deaths: a definitional and diagnostic approach Pediatrics. 2004 Jul; 114(1):234-8. . View in PubMed

Temporal trends of cardiac and respiratory responses to ventilatory challenges in congenital central hypoventilation syndrome Pediatr Res. 2004 Jun; 55(6):953-9. . View in PubMed

Infant sleep positioning by nursery staff and mothers in newborn hospital nurseries Nurs Res. 2004 Mar-Apr; 53(2):122-9. . View in PubMed

Obstructive hypopneas in children and adolescents: normal values Am J Respir Crit Care Med. 2003 Dec 15; 168(12):1540. . View in PubMed

Bordetella bronchiseptica infection in pediatric lung transplant recipients Pediatr Transplant. 2003 Oct; 7(5):413-7. . View in PubMed

What are the best pulmonary function test parameters for early detection of post-lung transplant bronchiolitis obliterans syndrome in children? Pediatr Transplant. 2003 Jun; 7(3):200-3.. View in PubMed

Initiation of home mechanical ventilation in children with neuromuscular diseases J Pediatr. 2003 May; 142(5):481-5. . View in PubMed

Does lung growth occur when mature lobes are transplanted into children? Pediatr Transplant. 2002 Dec; 6(6):500-4.. View in PubMed

Mother-daughter transmission of congenital central hypoventilation syndrome Am J Respir Crit Care Med. 2002 Aug 01; 166(3):367-9. . View in PubMed

Thoracoscopic placement of phrenic nerve electrodes for diaphragmatic pacing in children J Pediatr Surg. 2002 Jul; 37(7):974-8; discussion 974-8. . View in PubMed

Correlation between digital clubbing and pulmonary function in cystic fibrosis Pediatr Pulmonol. 2002 May; 33(5):332-8. . View in PubMed

Does radiation research in healthy children pose greater than minimal risk? IRB. 1994 Sep-Oct; 16(5):5-10.. View in PubMed

The effect of scoliosis surgery on lung function in the immediate postoperative period Spine (Phila Pa 1976). 2005 Oct 01; 30(19):2182-5. . View in PubMed

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