Keck School Faculty

Thomas G Keens

Thomas G Keens

Professor of Pediatrics
Pediatrics
CHL Mail Stop 83 Off Campus Los Angeles

Comparison of SIMV+PS and AC modes in chronically ventilated children and effects on speechg Pediatr Pulmonol. 2020 Oct 02. . View in PubMed

Correction to: Life-threatening cardiac arrhythmias in congenital central hypoventilation syndrome Eur J Pediatr. 2020 07; 179(7):1173. . View in PubMed

Abnormal Lung Clearance Index in Cystic Fibrosis Screen Positive, Inconclusive Diagnosis (CFSPID) Children with Otherwise Normal FEV1 Lung. 2020 02; 198(1):163-167. . View in PubMed

Abnormalities in autonomic function in obese boys at-risk for insulin resistance and obstructive sleep apnea Pediatr Res. 2019 05; 85(6):790-798. . View in PubMed

Congenital central hypoventilation syndrome: diagnosis and management Expert Rev Respir Med. 2018 04; 12(4):283-292. . View in PubMed

Adult With PHOX2B Mutation and Late-Onset Congenital Central Hypoventilation Syndrome J Clin Sleep Med. 2018 12 15; 14(12):2079-2081. . View in PubMed

A System Analysis of Delay in Outpatient Respiratory Equipment Delivery Care Manag J. 2016 Dec 01; 17(4):161-169. . View in PubMed

Children and Young Adults Who Received Tracheostomies or Were Initiated on Long-Term Ventilation in PICUs Pediatr Crit Care Med. 2016 08; 17(8):e324-34. . View in PubMed

Forensic Sci Med Pathol. 2016 06; 12(2):229-31. . View in PubMed

Benign and Deleterious Cystic Fibrosis Transmembrane Conductance Regulator Mutations Identified by Sequencing in Positive Cystic Fibrosis Newborn Screen Children from California PLoS One. 2016; 11(5):e0155624. . View in PubMed

Congenital central hypoventilation syndrome: diagnostic and management challenges Pediatric Health Med Ther. 2016; 7:99-107. . View in PubMed

Benign outcome among positive cystic fibrosis newborn screen children with non-CF-causing variants J Cyst Fibros. 2015 Nov; 14(6):714-9. . View in PubMed

Body Fat Composition: A Predictive Factor for Sleep Related Breathing Disorder in Obese Children J Clin Sleep Med. 2015 Sep 15; 11(9):1039-45. . View in PubMed

A physician survey reveals differences in management of idiopathic pulmonary hemosiderosis Orphanet J Rare Dis. 2015 Aug 20; 10:98. . View in PubMed

Examining pediatric emergency home ventilation practices in home health nurses: Opportunities for improved care Pediatr Pulmonol. 2015 Jul; 50(7):691-7. . View in PubMed

Correlation of pulmonary function abnormalities with dose volume histograms in children treated with lung irradiation Pediatr Pulmonol. 2015 Jun; 50(6):596-603. . View in PubMed

Diaphragm Pacing without Tracheostomy in Congenital Central Hypoventilation Syndrome Patients Respiration. 2015; 89(6):534-8. . View in PubMed

[ATS clinical policy statement: congenital central hypoventilation syndromeGenetic basis, diagnosis and management]. Rev Mal Respir. 2013 Oct; 30(8):706-33. . View in PubMed

Correlation of clinical and dosimetric factors with adverse pulmonary outcomes in children after lung irradiation Int J Radiat Oncol Biol Phys. 2013 Aug 01; 86(5):942-8. . View in PubMed

Exercise performance in thalassemia major: correlation with cardiac iron burden Am J Hematol. 2013 Mar; 88(3):193-7. . View in PubMed

Effect of residential proximity to major roadways on cystic fibrosis exacerbations Int J Environ Health Res. 2013; 23(2):119-31. . View in PubMed

Hospital readmissions for newly discharged pediatric home mechanical ventilation patients Pediatr Pulmonol. 2012 Apr; 47(4):409-14. . View in PubMed

End-of-life discussions and advance care planning for children on long-term assisted ventilation with life-limiting conditions J Palliat Care. 2012; 28(1):21-7. . View in PubMed

Costs of hospitalized ventilator-dependent children: differences between a ventilator ward and intensive care unit Pediatr Pulmonol. 2011 Apr; 46(4):356-61. . View in PubMed

Children with corrected or palliated congenital heart disease on home mechanical ventilation Pediatr Pulmonol. 2010 Jul; 45(7):645-9. . View in PubMed

An official ATS clinical policy statement: Congenital central hypoventilation syndrome: genetic basis, diagnosis, and management Am J Respir Crit Care Med. 2010 Mar 15; 181(6):626-44. . View in PubMed

How much do primary care givers know about tracheostomy and home ventilator emergency care? Pediatr Pulmonol. 2010 Mar; 45(3):270-4.. View in PubMed

Does the 6-min walk test correlate with the exercise stress test in children? Pediatr Pulmonol. 2010 Feb; 45(2):135-40.. View in PubMed

Autonomic and metabolic effects of OSA in childhood obesity Annu Int Conf IEEE Eng Med Biol Soc. 2010; 2010:6134-7. . View in PubMed

Do sequential chest radiographs prompt changes in therapy for home mechanical ventilation children admitted for pneumonia? Care Manag J. 2010; 11(4):217-9.. View in PubMed

Congenital hypoventilation syndromes Semin Respir Crit Care Med. 2009 Jun; 30(3):339-47. . View in PubMed

Do all infants with apparent life-threatening events need to be admitted? Pediatrics. 2007 Apr; 119(4):679-83.. View in PubMed

Alcohol use in congenital central hypoventilation syndrome Pediatr Pulmonol. 2006 Mar; 41(3):283-5. . View in PubMed

Diaphragm pacers as a treatment for congenital central hypoventilation syndrome Expert Rev Med Devices. 2005 Sep; 2(5):577-85. . View in PubMed

Disordered respiratory control in children with partial cerebellar resections Pediatr Pulmonol. 2005 Jul; 40(1):88-91. . View in PubMed

FMRI responses to hyperoxia in congenital central hypoventilation syndrome Pediatr Res. 2005 Apr; 57(4):510-8. . View in PubMed

Aberrant neural responses to cold pressor challenges in congenital central hypoventilation syndrome Pediatr Res. 2005 Apr; 57(4):500-9. . View in PubMed

Hypercapnic exposure in congenital central hypoventilation syndrome reveals CNS respiratory control mechanisms J Neurophysiol. 2005 Mar; 93(3):1647-58. . View in PubMed

Cardio-respiratory Uncoupling in Congenital Central Hypoventilation Syndrome Conf Proc IEEE Eng Med Biol Soc. 2005; 2005:4412-5. . View in PubMed

Congenital central hypoventilation syndrome: not just another rare disorder Paediatr Respir Rev. 2004 Sep; 5(3):182-9. . View in PubMed

Bordetella bronchiseptica infection in pediatric lung transplant recipients Pediatr Transplant. 2003 Oct; 7(5):413-7. . View in PubMed

Does lung growth occur when mature lobes are transplanted into children? Pediatr Transplant. 2002 Dec; 6(6):500-4.. View in PubMed

Correlation between digital clubbing and pulmonary function in cystic fibrosis Pediatr Pulmonol. 2002 May; 33(5):332-8. . View in PubMed

Cardiorespiratory events recorded on home monitors: Comparison of healthy infants with those at increased risk for SIDS JAMA. 2001 May 02; 285(17):2199-207. . View in PubMed

Bronchoscopic instillation of surfactant in acute respiratory distress syndrome Pediatr Pulmonol. 2001 Apr; 31(4):317-20. . View in PubMed

Home ventilator low-pressure alarms fail to detect accidental decannulation with pediatric tracheostomy tubes Chest. 2001 Feb; 119(2):562-4. . View in PubMed

Frequency, causes, and outcome of home ventilator failure Chest. 1998 Nov; 114(5):1363-7. . View in PubMed

Factors associated with the transition to nonprone sleep positions of infants in the United States: the National Infant Sleep Position Study JAMA. 1998 Jul 22-29; 280(4):329-35. . View in PubMed

Determinants of aerobic and anaerobic exercise performance in cystic fibrosis Am J Respir Crit Care Med. 1998 Apr; 157(4 Pt 1):1145-50. . View in PubMed

How many maneuvers are required to measure maximal inspiratory pressure accurately Chest. 1997 Mar; 111(3):802-7. . View in PubMed

Arousal and cardiorespiratory responses to hypoxia in Prader-Willi syndrome Am J Respir Crit Care Med. 1996 Jan; 153(1):283-7. . View in PubMed

Effects of overnight supplemental oxygen in obstructive sleep apnea in children Am J Respir Crit Care Med. 1996 Jan; 153(1):51-5. . View in PubMed

Hypercapnic arousal responses in Prader-Willi syndrome Chest. 1995 Dec; 108(6):1627-31. . View in PubMed

Comparison of dynamic and passive measurements of respiratory mechanics in ventilated newborn infants Pediatr Pulmonol. 1995 Oct; 20(4):258-64. . View in PubMed

Comparison of high frequency chest compression and conventional chest physiotherapy in hospitalized patients with cystic fibrosis Am J Respir Crit Care Med. 1994 Oct; 150(4):1154-7. . View in PubMed

Does radiation research in healthy children pose greater than minimal risk? IRB. 1994 Sep-Oct; 16(5):5-10.. View in PubMed

Home exercise training for cystic fibrosis patients Chest. 1994 Feb; 105(2):334-5. . View in PubMed

Evolution of pulmonary function during an acute exacerbation in hospitalized patients with cystic fibrosis Pediatr Pulmonol. 1993 Dec; 16(6):347-53. . View in PubMed

Apnea spells, sudden death, and the role of the apnea monitor Pediatr Clin North Am. 1993 Oct; 40(5):897-911. . View in PubMed

Hypercapnic and hypoxic ventilatory and cardiac responses in school-aged siblings of sudden infant death syndrome victims J Pediatr. 1992 Sep; 121(3):391-7. . View in PubMed

Hypoventilation and apnea in children during mechanically assisted ventilation Chest. 1992 Jun; 101(6):1500-6. . View in PubMed

Comparison of nap and overnight polysomnography in children Pediatr Pulmonol. 1992 May; 13(1):16-21. . View in PubMed

Heart rate variability in congenital central hypoventilation syndrome Pediatr Res. 1992 Mar; 31(3):291-6. . View in PubMed

Hypercapneic arousal responses in children with congenital central hypoventilation syndrome Pediatrics. 1991 Nov; 88(5):993-8. . View in PubMed

Hypercapnic and hypoxic ventilatory responses in parents and siblings of children with congenital central hypoventilation syndrome Am Rev Respir Dis. 1991 Jul; 144(1):136-40. . View in PubMed

Digital clubbing and pulmonary function abnormalities in children with lung disease Pediatr Pulmonol. 1991; 10(1):25-9. . View in PubMed

Abnormal control of ventilation in adolescents with myelodysplasia J Pediatr. 1989 Dec; 115(6):898-903. . View in PubMed

Congenital central hypoventilation syndrome associated with multiple ganglioneuromas Chest. 1989 Aug; 96(2):423-4. . View in PubMed

Fundamental considerations in pacing of the diaphragm for chronic ventilatory insufficiency: a multi-center study Pacing Clin Electrophysiol. 1988 Nov; 11(11 Pt 2):2121-7. . View in PubMed

Evaluation of a new, shorter method of administration of adrenergic aerosols in the treatment of asthma Ann Allergy. 1988 Aug; 61(2):147-50. . View in PubMed

Clinically unsuspected hypoxia during sleep and feeding in infants with bronchopulmonary dysplasia Pediatrics. 1988 May; 81(5):635-42. . View in PubMed

Growth failure in infants with bronchopulmonary dysplasia: nutrition and elevated resting metabolic expenditure Pediatrics. 1988 Mar; 81(3):379-84. . View in PubMed

Growth failure in bronchopulmonary dysplasia: elevated metabolic rates and pulmonary mechanics J Pediatr. 1988 Jan; 112(1):73-80. . View in PubMed

Childhood sequelae of infant lung disease: exercise and pulmonary function abnormalities after bronchopulmonary dysplasia J Pediatr. 1987 May; 110(5):693-9. . View in PubMed

Elevated catecholamine levels and abnormal hypoxic arousal in apnea of infancy Pediatrics. 1987 Feb; 79(2):269-74. . View in PubMed

A comparison of pneumogram recordings in infants in the hospital and at home Pediatr Pulmonol. 1986 Nov-Dec; 2(6):373-7. . View in PubMed

Abnormal sleeping ventilatory pattern in infants of substance-abusing mothers Am J Dis Child. 1986 Oct; 140(10):1015-20. . View in PubMed

Abnormal ventilatory patterns during sleep in infants with myelomeningocele J Pediatr. 1986 Oct; 109(4):631-4. . View in PubMed

Absent hypoxic and hypercapneic arousal responses in children with myelomeningocele and apnea Pediatrics. 1986 Jul; 78(1):44-50. . View in PubMed

Decreased specific airway conductance in infant apnea Pediatrics. 1985 Aug; 76(2):232-5. . View in PubMed

Absent peripheral chemosensitivity in Prader-Willi syndrome J Appl Physiol (1985). 1994 Nov; 77(5):2231-6. . View in PubMed

fMRI signal changes in response to forced expiratory loading in congenital central hypoventilation syndrome J Appl Physiol (1985). 2004 Nov; 97(5):1897-907. . View in PubMed

Developmental pattern of hypercapnic and hypoxic ventilatory responses from childhood to adulthood J Appl Physiol (1985). 1994 Jan; 76(1):314-20. . View in PubMed

Effect of supplemental oxygen on supramaximal exercise performance and recovery in cystic fibrosis J Appl Physiol (1985). 1997 Nov; 83(5):1641-7. . View in PubMed

Effect of oral diuretics on pulmonary mechanics in infants with chronic bronchopulmonary dysplasia: results of a double-blind crossover sequential trial Pediatrics. 1984 Jul; 74(1):37-44. . View in PubMed

Effect of isoproterenol inhalation on airway resistance in chronic bronchopulmonary dysplasia Pediatrics. 1984 Apr; 73(4):509-14. . View in PubMed

Effect of experimental dysthyroidism on the enzymatic character of the diaphragm J Appl Physiol Respir Environ Exerc Physiol. 1984 Jan; 56(1):117-21. . View in PubMed

Furosemide acutely decreases airways resistance in chronic bronchopulmonary dysplasia J Pediatr. 1983 Oct; 103(4):624-9. . View in PubMed

Developmental pattern of maximal transdiaphragmatic pressure in infants during crying Pediatr Res. 1983 Sep; 17(9):707-9. . View in PubMed

Distance running improves fitness in asthmatic children without pulmonary complications or changes in exercise-induced bronchospasm Pediatrics. 1983 Feb; 71(2):147-52. . View in PubMed

Diaphragm strength in near-miss sudden infant death syndrome Pediatrics. 1982 Jun; 69(6):782-4. . View in PubMed

Circulating immune complexes in patients with cystic fibrosis Chest. 1981 Oct; 80(4):405-11. . View in PubMed

Function of the diaphragm before and after plication Thorax. 1980 Aug; 35(8):631-2. . View in PubMed

Exercise training programs for pediatric patients with chronic lung disease Pediatr Clin North Am. 1979 Aug; 26(3):517-24. . View in PubMed

Evaluation of the single-breath diffusing capacity in asthma and cystic fibrosis Chest. 1979 Jul; 76(1):41-4. . View in PubMed

Development of fatigue-resistant muscle fibers in human ventilatory muscles Am Rev Respir Dis. 1979 Feb; 119(2 Pt 2):139-41. . View in PubMed

Developmental pattern of muscle fiber types in human ventilatory muscles J Appl Physiol Respir Environ Exerc Physiol. 1978 Jun; 44(6):909-13. . View in PubMed

Cellular adaptations of the ventilatory muscles to a chronic increased respiratory load J Appl Physiol Respir Environ Exerc Physiol. 1978 Jun; 44(6):905-8. . View in PubMed

Comparative study of histamine and exercise challenges in asthmatic children Am Rev Respir Dis. 1978 May; 117(5):911-5. . View in PubMed

Effects of gravity on tracheal mucus transport rates in normal subjects and in patients with cystic fibrosis Pediatrics. 1977 Aug; 60(2):146-52. . View in PubMed

An expert on respiratory and pulmonary disorders in children, including sudden infant death syndrome
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