Keck School Faculty

Thomas G Keens, MD
Thomas G Keens, MD
Professor of Pediatrics
Pediatrics
CHL Mail Stop 83 Off Campus Los Angeles
An expert on respiratory and pulmonary disorders in children, including sudden infant death syndrome

Abnormalities in autonomic function in obese boys at-risk for insulin resistance and obstructive sleep apnea Pediatr Res. 2019 May; 85(6):790-798. . View in PubMed

Congenital central hypoventilation syndrome: diagnosis and management Expert Rev Respir Med. 2018 04; 12(4):283-292. . View in PubMed

Adult With PHOX2B Mutation and Late-Onset Congenital Central Hypoventilation Syndrome J Clin Sleep Med. 2018 12 15; 14(12):2079-2081. . View in PubMed

A System Analysis of Delay in Outpatient Respiratory Equipment Delivery Care Manag J. 2016 Dec 01; 17(4):161-169. . View in PubMed

Children and Young Adults Who Received Tracheostomies or Were Initiated on Long-Term Ventilation in PICUs Pediatr Crit Care Med. 2016 08; 17(8):e324-34. . View in PubMed

Forensic Sci Med Pathol. 2016 06; 12(2):229-31. . View in PubMed

Benign and Deleterious Cystic Fibrosis Transmembrane Conductance Regulator Mutations Identified by Sequencing in Positive Cystic Fibrosis Newborn Screen Children from California PLoS One. 2016; 11(5):e0155624. . View in PubMed

Congenital central hypoventilation syndrome: diagnostic and management challenges Pediatric Health Med Ther. 2016; 7:99-107. . View in PubMed

Benign outcome among positive cystic fibrosis newborn screen children with non-CF-causing variants J Cyst Fibros. 2015 Nov; 14(6):714-9. . View in PubMed

Body Fat Composition: A Predictive Factor for Sleep Related Breathing Disorder in Obese Children J Clin Sleep Med. 2015 Sep 15; 11(9):1039-45. . View in PubMed

A physician survey reveals differences in management of idiopathic pulmonary hemosiderosis Orphanet J Rare Dis. 2015 Aug 20; 10:98. . View in PubMed

Examining pediatric emergency home ventilation practices in home health nurses: Opportunities for improved care Pediatr Pulmonol. 2015 Jul; 50(7):691-7. . View in PubMed

Correlation of pulmonary function abnormalities with dose volume histograms in children treated with lung irradiation Pediatr Pulmonol. 2015 Jun; 50(6):596-603. . View in PubMed

Diaphragm Pacing without Tracheostomy in Congenital Central Hypoventilation Syndrome Patients Respiration. 2015; 89(6):534-8. . View in PubMed

[ATS clinical policy statement: congenital central hypoventilation syndromeGenetic basis, diagnosis and management]. Rev Mal Respir. 2013 Oct; 30(8):706-33. . View in PubMed

Correlation of clinical and dosimetric factors with adverse pulmonary outcomes in children after lung irradiation Int J Radiat Oncol Biol Phys. 2013 Aug 01; 86(5):942-8. . View in PubMed

Exercise performance in thalassemia major: correlation with cardiac iron burden Am J Hematol. 2013 Mar; 88(3):193-7. . View in PubMed

Effect of residential proximity to major roadways on cystic fibrosis exacerbations Int J Environ Health Res. 2013; 23(2):119-31. . View in PubMed

Hospital readmissions for newly discharged pediatric home mechanical ventilation patients Pediatr Pulmonol. 2012 Apr; 47(4):409-14. . View in PubMed

End-of-life discussions and advance care planning for children on long-term assisted ventilation with life-limiting conditions J Palliat Care. 2012; 28(1):21-7. . View in PubMed

Costs of hospitalized ventilator-dependent children: differences between a ventilator ward and intensive care unit Pediatr Pulmonol. 2011 Apr; 46(4):356-61. . View in PubMed

Children with corrected or palliated congenital heart disease on home mechanical ventilation Pediatr Pulmonol. 2010 Jul; 45(7):645-9. . View in PubMed

An official ATS clinical policy statement: Congenital central hypoventilation syndrome: genetic basis, diagnosis, and management Am J Respir Crit Care Med. 2010 Mar 15; 181(6):626-44. . View in PubMed

How much do primary care givers know about tracheostomy and home ventilator emergency care? Pediatr Pulmonol. 2010 Mar; 45(3):270-4.. View in PubMed

Does the 6-min walk test correlate with the exercise stress test in children? Pediatr Pulmonol. 2010 Feb; 45(2):135-40.. View in PubMed

Do sequential chest radiographs prompt changes in therapy for home mechanical ventilation children admitted for pneumonia? Care Manag J. 2010; 11(4):217-9.. View in PubMed

Autonomic and metabolic effects of OSA in childhood obesity Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:6134-7. . View in PubMed

Congenital hypoventilation syndromes Semin Respir Crit Care Med. 2009 Jun; 30(3):339-47. . View in PubMed

Do all infants with apparent life-threatening events need to be admitted? Pediatrics. 2007 Apr; 119(4):679-83.. View in PubMed

Alcohol use in congenital central hypoventilation syndrome Pediatr Pulmonol. 2006 Mar; 41(3):283-5. . View in PubMed

Diaphragm pacers as a treatment for congenital central hypoventilation syndrome Expert Rev Med Devices. 2005 Sep; 2(5):577-85. . View in PubMed

Disordered respiratory control in children with partial cerebellar resections Pediatr Pulmonol. 2005 Jul; 40(1):88-91. . View in PubMed

Aberrant neural responses to cold pressor challenges in congenital central hypoventilation syndrome Pediatr Res. 2005 Apr; 57(4):500-9. . View in PubMed

FMRI responses to hyperoxia in congenital central hypoventilation syndrome Pediatr Res. 2005 Apr; 57(4):510-8. . View in PubMed

Hypercapnic exposure in congenital central hypoventilation syndrome reveals CNS respiratory control mechanisms J Neurophysiol. 2005 Mar; 93(3):1647-58. . View in PubMed

Cardio-respiratory Uncoupling in Congenital Central Hypoventilation Syndrome Conf Proc IEEE Eng Med Biol Soc. 2005; 4:4412-5. . View in PubMed

Congenital central hypoventilation syndrome: not just another rare disorder Paediatr Respir Rev. 2004 Sep; 5(3):182-9. . View in PubMed

Bordetella bronchiseptica infection in pediatric lung transplant recipients Pediatr Transplant. 2003 Oct; 7(5):413-7. . View in PubMed

Does lung growth occur when mature lobes are transplanted into children? Pediatr Transplant. 2002 Dec; 6(6):500-4.. View in PubMed

Correlation between digital clubbing and pulmonary function in cystic fibrosis Pediatr Pulmonol. 2002 May; 33(5):332-8. . View in PubMed

Cardiorespiratory events recorded on home monitors: Comparison of healthy infants with those at increased risk for SIDS JAMA. 2001 May 02; 285(17):2199-207. . View in PubMed

Bronchoscopic instillation of surfactant in acute respiratory distress syndrome Pediatr Pulmonol. 2001 Apr; 31(4):317-20. . View in PubMed

Home ventilator low-pressure alarms fail to detect accidental decannulation with pediatric tracheostomy tubes Chest. 2001 Feb; 119(2):562-4. . View in PubMed

Frequency, causes, and outcome of home ventilator failure Chest. 1998 Nov; 114(5):1363-7. . View in PubMed

Factors associated with the transition to nonprone sleep positions of infants in the United States: the National Infant Sleep Position Study JAMA. 1998 Jul 22-29; 280(4):329-35. . View in PubMed

Determinants of aerobic and anaerobic exercise performance in cystic fibrosis Am J Respir Crit Care Med. 1998 Apr; 157(4 Pt 1):1145-50. . View in PubMed

How many maneuvers are required to measure maximal inspiratory pressure accurately Chest. 1997 Mar; 111(3):802-7. . View in PubMed

Arousal and cardiorespiratory responses to hypoxia in Prader-Willi syndrome Am J Respir Crit Care Med. 1996 Jan; 153(1):283-7. . View in PubMed

Effects of overnight supplemental oxygen in obstructive sleep apnea in children Am J Respir Crit Care Med. 1996 Jan; 153(1):51-5. . View in PubMed

Hypercapnic arousal responses in Prader-Willi syndrome Chest. 1995 Dec; 108(6):1627-31. . View in PubMed

Comparison of dynamic and passive measurements of respiratory mechanics in ventilated newborn infants Pediatr Pulmonol. 1995 Oct; 20(4):258-64. . View in PubMed

Comparison of high frequency chest compression and conventional chest physiotherapy in hospitalized patients with cystic fibrosis Am J Respir Crit Care Med. 1994 Oct; 150(4):1154-7. . View in PubMed

Does radiation research in healthy children pose greater than minimal risk? IRB. 1994 Sep-Oct; 16(5):5-10.. View in PubMed

Home exercise training for cystic fibrosis patients Chest. 1994 Feb; 105(2):334-5. . View in PubMed

Evolution of pulmonary function during an acute exacerbation in hospitalized patients with cystic fibrosis Pediatr Pulmonol. 1993 Dec; 16(6):347-53. . View in PubMed

Apnea spells, sudden death, and the role of the apnea monitor Pediatr Clin North Am. 1993 Oct; 40(5):897-911. . View in PubMed

Hypercapnic and hypoxic ventilatory and cardiac responses in school-aged siblings of sudden infant death syndrome victims J Pediatr. 1992 Sep; 121(3):391-7. . View in PubMed

Hypoventilation and apnea in children during mechanically assisted ventilation Chest. 1992 Jun; 101(6):1500-6. . View in PubMed

Comparison of nap and overnight polysomnography in children Pediatr Pulmonol. 1992 May; 13(1):16-21. . View in PubMed

Heart rate variability in congenital central hypoventilation syndrome Pediatr Res. 1992 Mar; 31(3):291-6. . View in PubMed

Hypercapneic arousal responses in children with congenital central hypoventilation syndrome Pediatrics. 1991 Nov; 88(5):993-8. . View in PubMed

Hypercapnic and hypoxic ventilatory responses in parents and siblings of children with congenital central hypoventilation syndrome Am Rev Respir Dis. 1991 Jul; 144(1):136-40. . View in PubMed

Digital clubbing and pulmonary function abnormalities in children with lung disease Pediatr Pulmonol. 1991; 10(1):25-9. . View in PubMed

Abnormal control of ventilation in adolescents with myelodysplasia J Pediatr. 1989 Dec; 115(6):898-903. . View in PubMed

Hypoxic and hypercapnic ventilatory responses in awake children with congenital central hypoventilation syndrome Am Rev Respir Dis. 1989 Aug; 140(2):368-72. . View in PubMed

Congenital central hypoventilation syndrome associated with multiple ganglioneuromas Chest. 1989 Aug; 96(2):423-4. . View in PubMed

Fundamental considerations in pacing of the diaphragm for chronic ventilatory insufficiency: a multi-center study Pacing Clin Electrophysiol. 1988 Nov; 11(11 Pt 2):2121-7. . View in PubMed

Evaluation of a new, shorter method of administration of adrenergic aerosols in the treatment of asthma Ann Allergy. 1988 Aug; 61(2):147-50. . View in PubMed

Clinically unsuspected hypoxia during sleep and feeding in infants with bronchopulmonary dysplasia Pediatrics. 1988 May; 81(5):635-42. . View in PubMed

Growth failure in infants with bronchopulmonary dysplasia: nutrition and elevated resting metabolic expenditure Pediatrics. 1988 Mar; 81(3):379-84. . View in PubMed

Growth failure in bronchopulmonary dysplasia: elevated metabolic rates and pulmonary mechanics J Pediatr. 1988 Jan; 112(1):73-80. . View in PubMed

Childhood sequelae of infant lung disease: exercise and pulmonary function abnormalities after bronchopulmonary dysplasia J Pediatr. 1987 May; 110(5):693-9. . View in PubMed

Elevated catecholamine levels and abnormal hypoxic arousal in apnea of infancy Pediatrics. 1987 Feb; 79(2):269-74. . View in PubMed

A comparison of pneumogram recordings in infants in the hospital and at home Pediatr Pulmonol. 1986 Nov-Dec; 2(6):373-7. . View in PubMed

Abnormal ventilatory patterns during sleep in infants with myelomeningocele J Pediatr. 1986 Oct; 109(4):631-4. . View in PubMed

Abnormal sleeping ventilatory pattern in infants of substance-abusing mothers Am J Dis Child. 1986 Oct; 140(10):1015-20. . View in PubMed

Absent hypoxic and hypercapneic arousal responses in children with myelomeningocele and apnea Pediatrics. 1986 Jul; 78(1):44-50. . View in PubMed

Decreased specific airway conductance in infant apnea Pediatrics. 1985 Aug; 76(2):232-5. . View in PubMed

Hypoxic and hypercapneic arousal responses and prediction of subsequent apnea in apnea of infancy Pediatrics. 1985 May; 75(5):848-54. . View in PubMed

fMRI signal changes in response to forced expiratory loading in congenital central hypoventilation syndrome J Appl Physiol (1985). 2004 Nov; 97(5):1897-907. . View in PubMed

Absent peripheral chemosensitivity in Prader-Willi syndrome J Appl Physiol (1985). 1994 Nov; 77(5):2231-6. . View in PubMed

Effect of supplemental oxygen on supramaximal exercise performance and recovery in cystic fibrosis J Appl Physiol (1985). 1997 Nov; 83(5):1641-7. . View in PubMed

Developmental pattern of hypercapnic and hypoxic ventilatory responses from childhood to adulthood J Appl Physiol (1985). 1994 Jan; 76(1):314-20. . View in PubMed

Hypoxia reveals posterior thalamic, cerebellar, midbrain, and limbic deficits in congenital central hypoventilation syndrome J Appl Physiol (1985). 2005 Mar; 98(3):958-69. . View in PubMed

Effect of oral diuretics on pulmonary mechanics in infants with chronic bronchopulmonary dysplasia: results of a double-blind crossover sequential trial Pediatrics. 1984 Jul; 74(1):37-44. . View in PubMed

Effect of isoproterenol inhalation on airway resistance in chronic bronchopulmonary dysplasia Pediatrics. 1984 Apr; 73(4):509-14. . View in PubMed

Effect of experimental dysthyroidism on the enzymatic character of the diaphragm J Appl Physiol Respir Environ Exerc Physiol. 1984 Jan; 56(1):117-21. . View in PubMed

Furosemide acutely decreases airways resistance in chronic bronchopulmonary dysplasia J Pediatr. 1983 Oct; 103(4):624-9. . View in PubMed

Developmental pattern of maximal transdiaphragmatic pressure in infants during crying Pediatr Res. 1983 Sep; 17(9):707-9. . View in PubMed

Distance running improves fitness in asthmatic children without pulmonary complications or changes in exercise-induced bronchospasm Pediatrics. 1983 Feb; 71(2):147-52. . View in PubMed

Diaphragm strength in near-miss sudden infant death syndrome Pediatrics. 1982 Jun; 69(6):782-4. . View in PubMed

Circulating immune complexes in patients with cystic fibrosis Chest. 1981 Oct; 80(4):405-11. . View in PubMed

Function of the diaphragm before and after plication Thorax. 1980 Aug; 35(8):631-2. . View in PubMed

Exercise training programs for pediatric patients with chronic lung disease Pediatr Clin North Am. 1979 Aug; 26(3):517-24. . View in PubMed

Evaluation of the single-breath diffusing capacity in asthma and cystic fibrosis Chest. 1979 Jul; 76(1):41-4. . View in PubMed

Development of fatigue-resistant muscle fibers in human ventilatory muscles Am Rev Respir Dis. 1979 Feb; 119(2 Pt 2):139-41. . View in PubMed

Cellular adaptations of the ventilatory muscles to a chronic increased respiratory load J Appl Physiol Respir Environ Exerc Physiol. 1978 Jun; 44(6):905-8. . View in PubMed

Developmental pattern of muscle fiber types in human ventilatory muscles J Appl Physiol Respir Environ Exerc Physiol. 1978 Jun; 44(6):909-13. . View in PubMed

Comparative study of histamine and exercise challenges in asthmatic children Am Rev Respir Dis. 1978 May; 117(5):911-5. . View in PubMed

Effects of gravity on tracheal mucus transport rates in normal subjects and in patients with cystic fibrosis Pediatrics. 1977 Aug; 60(2):146-52. . View in PubMed

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