Dr. Grikscheit, a member of The Saban Research Institute's Developmental Biology and Regenerative Medicine program, envisions a better solution. The small intestine is an exquisitely regenerative organ. It is an elegant model to better understand organ-specific stem cells and the regenerative cells can be harnessed to make new gastrointestinal tissue for eventual clinical applications. Understanding how to generate tissue-engineered intestines, whether esophagus, stomach, small intestine, or colon, may also inform us how to expand the list of organs that can be tissue-engineered.
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