Keck School Faculty

Warren Louis Garner, MD
Warren Louis Garner, MD
Professor of Surgery
Surgery
1510 San Pablo St. Off Campus Los Angeles
Dr. Garner is an internationally renowned expert in the science and treatment of wounds and the scars that result from them. This is based on his clinical experience in the treatment of traumatic injuries, particularly burn injuries, and correcting the deformities that result from them. He is the Director of the LAC+USC Burn Center where he directs a multidisciplinary team which treats patients with burn and other traumatic skin injuries. With the treatment of these patients Dr Garner has developed specialized expertise and experience in the treatment of the scars and deformities that result from these injuries. He is also expert in the treatment of numerous other wound healing abnormalities of poorly healing wounds and injuries. He treats such patients in numerous health care systems within the greater Los Angeles region; Keck School of Medicine University Hospital, the LAC + USC medical center, Rancho Los Amigos Rehabilitative Center and he is the Burn and Burn Reconstructive consultant for Kaiser Permanente of Southern California. Dr. Garner and his research team investigate wound healing and scar formation in the laboratory and have received numerous federal (NIH) and industrial grants to study why wounds heal, why they do not heal and treatments for them. He has been an officer, committee chair or Board member of the Wound Healing Society, American Society of Plastic Surgeons and Plastic Surgery Research Council.

Combination therapy: Etanercept and intravenous immunoglobulin for the acute treatment of Stevens-Johnson syndrome/toxic epidermal necrolysis Burns. 2019 Nov; 45(7):1634-1638. . View in PubMed

Measuring gastric residual volumes in critically ill burn patients - A systematic review Burns. 2019 05; 45(3):509-525. . View in PubMed

Plast Reconstr Surg Glob Open. 2018 Oct; 6(10):e1900. . View in PubMed

How long are burn patients really NPO in the perioperative period and can we effectively correct the caloric deficit using an enteral feeding "Catch-up" protocol? Burns. 2018 12; 44(8):2006-2010.. View in PubMed

Acute Fluid Management of Large Burns: Pathophysiology, Monitoring, and Resuscitation Clin Plast Surg. 2017 Jul; 44(3):495-503. . View in PubMed

Steven Johnson Syndrome and Toxic Epidermal Necrolysis in a burn unit: A 15-year experience Burns. 2017 Feb; 43(1):200-205. . View in PubMed

Delayed-onset thrombocytopenia in a pediatric burn patient Am J Hematol. 2016 Sep; 91(9):958-60. . View in PubMed

Dual therapeutic functions of F-5 fragment in burn wounds: preventing wound progression and promoting wound healing in pigs Mol Ther Methods Clin Dev. 2016; 3:16041. . View in PubMed

Cost-effectiveness comparison between topical silver sulfadiazine and enclosed silver dressing for partial-thickness burn treatment J Burn Care Res. 2014 Jul-Aug; 35(4):284-90. . View in PubMed

Donor-site preferences in women during autologous skin grafting Plast Reconstr Surg. 2014 Mar; 133(3):378e-382e. . View in PubMed

Simulation of plastic surgery and microvascular procedures using perfused fresh human cadavers J Plast Reconstr Aesthet Surg. 2014 Feb; 67(2):e42-8. . View in PubMed

Summary of the 2012 ABA Burn Quality Consensus conference J Burn Care Res. 2013 Jul-Aug; 34(4):361-85. . View in PubMed

Incorporation of fresh tissue surgical simulation into plastic surgery education: maximizing extraclinical surgical experience J Surg Educ. 2013 Jul-Aug; 70(4):466-74. . View in PubMed

High frequency percussive ventilation and low FiO(2) Burns. 2012 Nov; 38(7):984-91. . View in PubMed

Discussion: mast cells are required in the proliferation and remodeling phases of microdeformational wound therapy Plast Reconstr Surg. 2011 Dec; 128(6):659e-60e. . View in PubMed

An open, parallel, randomized, comparative, multicenter study to evaluate the cost-effectiveness, performance, tolerance, and safety of a silver-containing soft silicone foam dressing (intervention) vs silver sulfadiazine cream J Burn Care Res. 2011 Nov-Dec; 32(6):617-26. . View in PubMed

A simplified procedure to reconstitute hair-producing skin Tissue Eng Part C Methods. 2011 Apr; 17(4):391-400. . View in PubMed

Gastric feedings effectively prophylax against upper gastrointestinal hemorrhage in burn patients J Burn Care Res. 2011 Mar-Apr; 32(2):263-8. . View in PubMed

Epithelial to mesenchymal transition in human skin wound healing is induced by tumor necrosis factor-alpha through bone morphogenic protein-2 Am J Pathol. 2010 May; 176(5):2247-58. . View in PubMed

Matrix metalloproteinase-9 delays wound healing in a murine wound model Surgery. 2010 Feb; 147(2):295-302. . View in PubMed

A ten-year experience with hemodialysis in burn patients at Los Angeles County + USC Medical Center J Burn Care Res. 2009 Sep-Oct; 30(5):832-5. . View in PubMed

Burn surge for Los Angeles County, California J Trauma. 2009 Aug; 67(2 Suppl):S143-6. . View in PubMed

Alpha1-antichymotrypsin activity correlates with and may modulate matrix metalloproteinase-9 in human acute wounds Wound Repair Regen. 2009 May-Jun; 17(3):418-26. . View in PubMed

Tumor necrosis factor-alpha induced expression of matrix metalloproteinase-9 through p21-activated kinase-1 BMC Immunol. 2009 Mar 19; 10:15. . View in PubMed

Proteolytic activation of matrix metalloproteinase-9 in skin wound healing is inhibited by alpha-1-antichymotrypsin J Invest Dermatol. 2008 Sep; 128(9):2334-42. . View in PubMed

Acute burns Plast Reconstr Surg. 2008 May; 121(5):311e-319e. . View in PubMed

Integra in lower extremity reconstruction after burn injury Plast Reconstr Surg. 2008 Apr; 121(4):1256-62. . View in PubMed

American Burn Association consensus conference to define sepsis and infection in burns J Burn Care Res. 2007 Nov-Dec; 28(6):776-90. . View in PubMed

TNF-alpha suppresses alpha-smooth muscle actin expression in human dermal fibroblasts: an implication for abnormal wound healing J Invest Dermatol. 2007 Nov; 127(11):2645-55. . View in PubMed

Rate of healing in skin-grafted burn wounds Plast Reconstr Surg. 2007 Aug; 120(2):451-6. . View in PubMed

Hypertrophic scar, wound contraction and hyper-hypopigmentation J Burn Care Res. 2007 Jul-Aug; 28(4):593-7. . View in PubMed

Interleukin-1alpha-induced proteolytic activation of metalloproteinase-9 by human skin Surgery. 2005 Nov; 138(5):932-9. . View in PubMed

Wound-healing perspectives Dermatol Clin. 2005 Apr; 23(2):181-92. . View in PubMed

Acute burn injury Clin Plast Surg. 2005 Apr; 32(2):187-93. . View in PubMed

Burn care in Los Angeles, California: LAC+USC experience 1994-2004 Burns. 2005 Jan; 31 Suppl 1:S32-5. . View in PubMed

Signals that initiate, augment, and provide directionality for human keratinocyte motility J Invest Dermatol. 2004 Oct; 123(4):622-33. . View in PubMed

Essential role of matrix metalloproteinases in interleukin-1-induced myofibroblastic activation of hepatic stellate cell in collagen J Biol Chem. 2004 Feb 06; 279(6):4820-8. . View in PubMed

Polytetrafluoroethylene facial implants: 15 years later Plast Reconstr Surg. 2004 Jan; 113(1):347-9. . View in PubMed

Fibrinogen inhibits fibroblast-mediated contraction of collagen Wound Repair Regen. 2003 Sep-Oct; 11(5):380-5. . View in PubMed

Inflammatory mediators in wound healing Surg Clin North Am. 2003 Jun; 83(3):483-507. . View in PubMed

Migration of human keratinocytes in plasma and serum and wound re-epithelialisation Lancet. 2003 Feb 15; 361(9357):574-6. . View in PubMed

Fibroproliferative scars Clin Plast Surg. 2003 Jan; 30(1):77-89. . View in PubMed

IL-8-stimulated expression of urokinase-type plasminogen activator in human skin and human epidermal cells J Surg Res. 2002 Aug; 106(2):328-34. . View in PubMed

Tumor necrosis factor-alpha-induced proteolytic activation of pro-matrix metalloproteinase-9 by human skin is controlled by down-regulating tissue inhibitor of metalloproteinase-1 and mediated by tissue-associated chymotrypsin-like proteinase J Biol Chem. 2002 Jul 26; 277(30):27319-27. . View in PubMed

Recombinant human platelet-derived growth factor and transforming growth factor-beta mediated contraction of human dermal fibroblast populated lattices is inhibited by Rho/GTPase inhibitor but does not require phosphatidylinositol-3' kinase Wound Repair Regen. 2002 May-Jun; 10(3):169-76. . View in PubMed

Transforming growth factor-beta - and tumor necrosis factor-alpha -mediated induction and proteolytic activation of MMP-9 in human skin J Biol Chem. 2001 Jun 22; 276(25):22341-50. . View in PubMed

TNF-alpha stimulates activation of pro-MMP2 in human skin through NF-(kappa)B mediated induction of MT1-MMP J Cell Sci. 2001 Jan; 114(Pt 1):131-139. . View in PubMed

The use of 5% mafenide acetate solution in the postgraft treatment of necrotizing fasciitis J Burn Care Rehabil. 2001 Jan-Feb; 22(1):35-40. . View in PubMed

Memory of past exposure to the chemokine IL-8 inhibits the contraction of fibroblast-populated collagen lattices Exp Mol Pathol. 2000 Dec; 69(3):242-7. . View in PubMed

Acute Burns Plast Reconstr Surg. 2000 Jun; 101(7):2482-2493. . View in PubMed

Acute burns Plast Reconstr Surg. 2000 Jun; 105(7):2482-92; quiz 2493; discussion 2494. . View in PubMed

Management of chemical injuries to the upper extremity Hand Clin. 2000 May; 16(2):215-24. . View in PubMed

Interleukin-8 levels and activity in delayed-healing human thermal wounds Wound Repair Regen. 2000 May-Jun; 8(3):216-25. . View in PubMed

Epidermal regulation of dermal fibroblast activity Plast Reconstr Surg. 1998 Jul; 102(1):135-9. . View in PubMed

If we are not plastic surgeons, who are we? Plast Reconstr Surg. 1998 Apr; 101(4):1123-4.. View in PubMed

Gore-Tex facial implantsPlastic Surgery Educational Foundation DATA Committee. Plast Reconstr Surg. 1997 Dec; 100(7):1899-900. . View in PubMed

Biomechanical alterations in normal skin and hypertrophic scar after thermal injury J Burn Care Rehabil. 1997 Mar-Apr; 18(2):104-8. . View in PubMed

Fibroblast responses to cytokines are maintained during aging Ann Plast Surg. 1995 Sep; 35(3):290-6. . View in PubMed

Increased types I and III collagen and transforming growth factor-beta 1 mRNA and protein in hypertrophic burn scar J Invest Dermatol. 1995 May; 104(5):750-4. . View in PubMed

The effect of essential fatty acid supplementation on keratinocyte replication Prostaglandins Leukot Essent Fatty Acids. 1995 May; 52(5):349-55. . View in PubMed

Hypertrophic scar fibroblasts accelerate collagen gel contraction Wound Repair Regen. 1995 Apr-Jun; 3(2):185-91. . View in PubMed

Excessive scarring as a consequence of healing Wound Repair Regen. 1995 Jan-Mar; 3(1):6-14. . View in PubMed

Morphological and immunochemical differences between keloid and hypertrophic scar Am J Pathol. 1994 Jul; 145(1):105-13. . View in PubMed

Acute skin injury releases neutrophil chemoattractants Surgery. 1994 Jul; 116(1):42-8. . View in PubMed

The role of xanthine oxidase and xanthine dehydrogenase in skin ischemia J Surg Res. 1994 Feb; 56(2):162-7. . View in PubMed

Burn wounds: infection and healing Am J Surg. 1994 Jan; 167(1A):46S-48S. . View in PubMed

Donor site repair Am J Surg. 1994 Jan; 167(1A):49S-51S. . View in PubMed

Phenotypic differences in cytokine responsiveness of hypertrophic scar versus normal dermal fibroblasts J Invest Dermatol. 1993 Dec; 101(6):875-9. . View in PubMed

Control of hemorrhage during renal failure with triglycyl-lysine-vasopressin Ann Plast Surg. 1993 Jul; 31(1):78-81. . View in PubMed

Effect of triglycyl-lysine-vasopressin on skin blood flow and blood loss during wound excision in patients with burns J Burn Care Rehabil. 1993 Jul-Aug; 14(4):458-60. . View in PubMed

Correlation of the local and systemic cytokine response with clinical outcome following thermal injury J Trauma. 1993 May; 34(5):684-94; discussion 694-5. . View in PubMed

The effects of burn blister fluid on keratinocyte replication and differentiation J Burn Care Rehabil. 1993 Mar-Apr; 14(2 Pt 1):127-31. . View in PubMed

Reconstruction of burns of the trunk and breast Clin Plast Surg. 1992 Jul; 19(3):683-91. . View in PubMed

Skin grafting: dermal components in inhibition of wound contraction South Med J. 1990 Jul; 83(7):789-95. . View in PubMed

The effects of hyperoxia during fulminant sepsis Surgery. 1989 Jun; 105(6):747-51. . View in PubMed

Identification of the collagen-producing cells in healing flexor tendons Plast Reconstr Surg. 1989 May; 83(5):875-9. . View in PubMed

Physical, biomechanical, histologic, and biochemical effects of rapid versus conventional tissue expansion Plast Reconstr Surg. 1989 Apr; 83(4):687-91. . View in PubMed

Real-time continuous estimation of gas exchange by dual oximetry Intensive Care Med. 1988; 14(2):118-22. . View in PubMed

Recurrent hypersplenism caused by alcoholic cardiomyopathy after distal splenorenal shunt Surgery. 1986 Apr; 99(4):514-6. . View in PubMed

Reye's syndrome associated with adenovirus infections in infants Am J Dis Child. 1985 Apr; 139(4):343-6. . View in PubMed

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