Keck School Faculty

Wensha Yang

Wensha Yang

Associate Professor Of Clinical Radiation Oncology
Radiation Oncology
1441 Eastlake Ave. Health Sciences Campus Los Angeles

Surviving Over a Decade With Glioblastoma: A Clinical Course Characterized by Multiple Recurrences, Numerous Salvage Treatments, and Novel Use of Cesium-131 TilesCureus. 2021; 7759(10):DOI: 10. 7759/cureus. 19573. . View in PubMed

MR multitasking-based dynamic imaging for cerebrovascular evaluation (MT-DICE): Simultaneous quantification of permeability and leakage-insensitive perfusion by dynamic T1/T2* mapping Magn Reson Med. 2022 Sep 21. . View in PubMed

Automatic segmentation of high-risk clinical target volume for tandem-and-ovoids brachytherapy patients using an asymmetric dual-path convolutional neural network Med Phys. 2022 Mar; 49(3):1712-1722. . View in PubMed

Voxelwise Prediction of Recurrent High-Grade Glioma via Proximity Estimation-Coupled Multidimensional Support Vector Machine Int J Radiat Oncol Biol Phys. 2022 04 01; 112(5):1279-1287. . View in PubMed

Anatomical and topographical variations in the distribution of brain metastases based on primary cancer origin and molecular subtypes: a systematic review Neurooncol Adv. 2022 Jan-Dec; 4(1):vdab170. . View in PubMed

A Quantitative Characterization of the Spatial Distribution of Brain Metastases from Breast Cancer and Respective Molecular Subtypes Journal of Neuro-Oncology. 2022. . View in PubMed

Single projection driven real-time multi-contrast (SPIDERM) MR imaging using pre-learned spatial subspace and linear transformation Phys Med Biol. 2022 06 27; 67(13). . View in PubMed

Automatic differentiation of Grade I and II meningiomas on magnetic resonance image using an asymmetric convolutional neural network Sci Rep. 2022 03 09; 12(1):3806. . View in PubMed

Bladder surface dose modeling in prostate cancer radiotherapy: An analysis of motion-induced variations and the cumulative dose across the treatment Med Phys. 2021 Dec; 48(12):8024-8036. . View in PubMed

Surviving Over a Decade With Glioblastoma: A Clinical Course Characterized by Multiple Recurrences, Numerous Salvage Treatments, and Novel Use of Cesium-131 Tiles Cureus. 2021 Nov; 13(11):e19573. . View in PubMed

Quantitative Characterization of Tumor Proximity to Stem Cell Niches: Implications on Recurrence and Survival in GBM Patients Int J Radiat Oncol Biol Phys. 2021 07 15; 110(4):1180-1188. . View in PubMed

Commensal bacteria and fungi differentially regulate tumor responses to radiation therapyCancer Cell. 2021 09 13; 39(9):1202-1213. e6. . View in PubMed

Automatic detection and segmentation of multiple brain metastases on magnetic resonance image using asymmetric UNet architecture Phys Med Biol. 2021 01 13; 66(1):015003. . View in PubMed

Fully automated multiorgan segmentation in abdominal magnetic resonance imaging with deep neural networks Med Phys. 2020 Oct; 47(10):4971-4982. . View in PubMed

Six-dimensional quantitative DCE MR Multitasking of the entire abdomen: Method and application to pancreatic ductal adenocarcinoma Magn Reson Med. 2020 08; 84(2):928-948. . View in PubMed

Six-dimensional quantitative DCE MR Multitasking of the entire abdomen: Method and application to pancreatic ductal adenocarcinoma Magnetic Resonance In Medicine. 2020. . View in PubMed

Quantifying vascular invasion in pancreatic cancer-a contrast CT based method for surgical resectability evaluation Phys Med Biol. 2020 06 01; 65(10):105012. . View in PubMed

A post-processing method based on interphase motion correction and averaging to improve image quality of 4D magnetic resonance imaging: a clinical feasibility study Br J Radiol. 2019 Mar; 92(1095):20180424. . View in PubMed

Combined morphologic and metabolic pipeline for Positron emission tomography/computed tomography based radiotherapy response evaluation in locally advanced pancreatic adenocarcinoma Phys Imaging Radiat Oncol. 2019 Jan; 9:28-34. . View in PubMed

Combined morphologic and metabolic pipeline for radiation therapy response evaluation in locally advanced pancreatic adenocarcinoma Physics and Imaging in Radiation Oncology. 2019; 9:28-34. . View in PubMed

Novel 4D-MRI of tumor infiltrating vasculature: characterizing tumor and vessel volume motion for selective boost volume definition in pancreatic radiotherapy Radiat Oncol. 2018 Oct 01; 13(1):191. . View in PubMed

Discriminating lung adenocarcinoma from lung squamous cell carcinoma using respiration-induced tumor shape changes Phys Med Biol. 2018 11 07; 63(21):215027. . View in PubMed

Improved vessel-tissue contrast and image quality in 3D radial sampling-based 4D-MRI J Appl Clin Med Phys. 2017 Nov; 18(6):250-257. . View in PubMed

Four-dimensional MRI using three-dimensional radial sampling with respiratory self-gating to characterize temporal phase-resolved respiratory motion in the abdomen Magn Reson Med. 2016 Apr; 75(4):1574-85. . View in PubMed

Nonlocal Means Denoising of Self-Gated and k-Space Sorted 4-Dimensional Magnetic Resonance Imaging Using Block-Matching and 3-Dimensional Filtering: Implications for Pancreatic Tumor Registration and Segmentation Int J Radiat Oncol Biol Phys. 2016 07 01; 95(3):1058-1066. . View in PubMed

Influence of Body Mass Index and Albumin on Perioperative Morbidity and Clinical Outcomes in Resected Pancreatic Adenocarcinoma PLoS One. 2016; 11(3):e0152172. . View in PubMed

Four-Dimensional Magnetic Resonance Imaging With 3-Dimensional Radial Sampling and Self-Gating-Based K-Space Sorting: Early Clinical Experience on Pancreatic Cancer Patients Int J Radiat Oncol Biol Phys. 2015 Dec 01; 93(5):1136-43. . View in PubMed

Geometric validation of self-gating k-space-sorted 4D-MRI vs 4D-CT using a respiratory motion phantom Med Phys. 2015 Oct; 42(10):5787-97. . View in PubMed

Clinical experience using a video-guided spirometry system for deep inhalation breath-hold radiotherapy of left-sided breast cancer J Appl Clin Med Phys. 2015 Mar 08; 16(2):5218. . View in PubMed

Dosimetric evaluation of simultaneous integrated boost during stereotactic body radiation therapy for pancreatic cancer Med Dosim. 2015; 40(1):47-52. . View in PubMed

Adequacy of inhale/exhale breathhold CT based ITV margins and image-guided registration for free-breathing pancreas and liver SBRT Radiat Oncol. 2014 Jan 09; 9:11. . View in PubMed

Computed tomography-based anatomic assessment overestimates local tumor recurrence in patients with mass-like consolidation after stereotactic body radiotherapy for early-stage non-small cell lung cancer Int J Radiat Oncol Biol Phys. 2012 Dec 01; 84(5):1071-7. . View in PubMed

3D dose verification using tomotherapy CT detector array Int J Radiat Oncol Biol Phys. 2012 Feb 01; 82(2):1013-20. . View in PubMed

Feasibility of non-coplanar tomotherapy for lung cancer stereotactic body radiation therapy Technol Cancer Res Treat. 2011 Aug; 10(4):307-15. . View in PubMed

Radiation therapy of post-mastectomy patients with positive nodes using fixed beam tomotherapy Radiother Oncol. 2011 Aug; 100(2):247-52. . View in PubMed

Standardized evaluation of simultaneous integrated boost plans on volumetric modulated arc therapy Phys Med Biol. 2011 Jan 21; 56(2):327-39. . View in PubMed

Dosimetric comparison of 6 MV and 15 MV single arc rapidarc to helical TomoTherapy for the treatment of pancreatic cancer Med Dosim. 2011; 36(3):317-20. . View in PubMed

Tumor cell apoptosis induced by nanoparticle conjugate in combination with radiation therapy Nanotechnology. 2010 Nov 26; 21(47):475103. . View in PubMed

Chest wall volume receiving >30 Gy predicts risk of severe pain and/or rib fracture after lung stereotactic body radiotherapy Int J Radiat Oncol Biol Phys. 2010 Mar 01; 76(3):796-801. . View in PubMed

Comparison of Elekta VMAT with helical tomotherapy and fixed field IMRT: plan quality, delivery efficiency and accuracy Med Phys. 2010 Mar; 37(3):1350-9. . View in PubMed

Helical tomotherapy-based STAT stereotactic body radiation therapy: Dosimetric evaluation for a real-time SBRT treatment planning and delivery program Med Dosim. 2010; 35(4):312-9. . View in PubMed

Tumor cell survival dependence on helical tomotherapy, continuous arc and segmented dose delivery Phys Med Biol. 2009 Nov 07; 54(21):6635-43. . View in PubMed

The implication of non-cyclic intrafractional longitudinal motion in SBRT by TomoTherapy Phys Med Biol. 2009 May 07; 54(9):2875-84. . View in PubMed

Spatial control in the heterogeneous nucleation of water Applied Physics Letters. 2009; 95(9):4101. . View in PubMed

Semiconductor nanoparticles as energy mediators for photosensitizer-enhanced radiotherapy Int J Radiat Oncol Biol Phys. 2008 Nov 01; 72(3):633-5. . View in PubMed

Direct electrical detection of antigen-antibody binding on diamond and silicon substrates using electrical impedance spectroscopy Analyst. 2007 Apr; 132(4):296-306. . View in PubMed

Covalent molecular functionalization of diamond thin-film transistors Diamond and Related Materials. 2007; 16(8):1608-1615. . View in PubMed

Electrical properties of diamond surfaces functionalized with molecular monolayers J Phys Chem B. 2005 May 05; 109(17):8523-32. . View in PubMed

Electrically Addressable Biomolecular Functionalization of Conductive Nanocrystalline Diamond Thin Films Chemistry of Materials. 2005; 5(17):938-940. . View in PubMed

Molecular and biomolecular monolayers on diamond as an interface to biology Diamond and Related Materials. 2005; 14(3-7):661-668. . View in PubMed

Interfacial electrical properties of DNA-modified diamond thin films: intrinsic response and hybridization-induced field effects Langmuir. 2004 Aug 03; 20(16):6778-87. . View in PubMed

Invasive cleavage reactions on DNA-modified diamond surfaces Biopolymers. 2004 Apr 05; 73(5):606-13. . View in PubMed

Electrically Addressable Biomolecular Functionalization of Carbon Nanotube and Carbon Nanofiber Electrodes Nano Letters. 2004; 9(4):1713-1716. . View in PubMed

Fabrication and characterization of a biologically sensitive field-effect transistor using a nanocrystalline diamond thin film Applied Physics Letters. 2004; 85:3626. . View in PubMed

DNA-modified nanocrystalline diamond thin-films as stable, biologically active substrates Nat Mater. 2002 Dec; 1(4):253-7. . View in PubMed

Preparation and Electrochemical Characterization of DNA-modified Nanocrystalline Diamond Films MRS Online Proceedings Library. 2002; (737):44. . View in PubMed

Anatomical and Topographical Variations in the Distribution of Brain Metastases Based on Primary Cancer Origin and Molecular Subtypes: A Systematic ReviewNeuro-Oncology Advances, vdab170, doi. org/10. 1093/noajnl/vdab170. 2021. . View in PubMed

Deformable alignment of longitudinal postoperative brain GBM scans using deep learningProc. SPIE 11313Medical Imaging 2020: Image Processing113130O (10 March 2020). 2020. . View in PubMed

Dr. Wensha Yang is an Associate Professor of Clinical Radiation Oncology-Medical Physics at USC Norris Cancer Hospital and USC+Los Angeles County Medical Center. She joined USC in March 2019. Dr. Yang graduated from University of Science and Technology of China with a Bachelor of Arts degree in material chemistry. She received her doctorate degree from the University of Wisconsin-Madison, and completed her clinical training in medical physics at University of Virginia in 2010. After completing her clinical training, Dr. Yang became a medical physicist on the faculty at Cedars Sinai Medical Center. Dr. Yang has published in multiple areas including material chemistry, medical physics, medical dosimetry and imaging guided radiation therapy. She had received NIH funding for her research in the area of MRI guided radiation therapy.

Medical Physics Expertise: SBRT, IGRT, DIBH, 4DCT, TBI, TSET, HDR, LDR

Languages Spoken: English and Chinese (Mandarin)
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