Keck School Faculty

Yuri S. Genyk

Yuri S. Genyk

Director, Pediatric Liver Transplantation at CHLA
Chief, Hepatobiliary, Pancreas and Abdomial Transplant Surgery
Professor Of Clinical Surgery
1510 San Pablo St. Health Sciences Campus Los Angeles

Normothermic Machine Perfusion of Donor Livers for Transplantation in the United States - A Randomized Controlled Trial Ann Surg. 2023 Jun 26. . View in PubMed

The influence of frailty on perioperative outcomes in patients undergoing surgical resection of liver metastases: a nationwide readmissions database study Ann Gastroenterol. 2023 May-Jun; 36(3):333-339. . View in PubMed

Living donor liver paired exchange between pediatric and adult recipients due to donor graft size mismatch Am J Transplant. 2023 03; 23(3):440-442. . View in PubMed

Transfusion-free Strategies in Liver and Pancreatic Surgery: A Predictive Model of Blood Conservation for Transfusion Avoidance in Mainstream Populations Ann Surg. 2023 03 01; 277(3):469-474. . View in PubMed

Living Liver Donation Does not Significantly Affect Long-Term Life, Disability, or Medical Insurability Prog Transplant. 2022 Dec; 32(4):274-282. . View in PubMed

Hospitalization Costs and Outcomes of Open, Laparoscopic, and Robotic Liver Resections Am Surg. 2022 Sep; 88(9):2331-2337. . View in PubMed

Arterial Anastomosis Using Microsurgical Techniques in Adult Live Donor Liver Transplant: A Focus on Technique and Outcomes at a Single Institution J Reconstr Microsurg. 2022 Jun 28. . View in PubMed

Assessing the perioperative complications and outcomes of robotic pancreaticoduodenectomy using the National Cancer Database: is it ready for prime time? J Robot Surg. 2022 Jun; 16(3):687-694.. View in PubMed

Microscope-Assisted Arterial Anastomosis in Adult Living Donor Liver Transplantation: A Systematic Review and Meta-analysis of Outcomes J Reconstr Microsurg. 2022 May; 38(4):306-312. . View in PubMed

Comprehensive analysis of laparoscopic, robotic, and open hepatectomy outcomes using the nationwide readmissions database J Robot Surg. 2022 Apr; 16(2):401-407. . View in PubMed

The role of graft to recipient weight ratio on enhanced recovery of the recipient after living donor liver transplantation - A systematic review of the literature and expert panel recommendations Clin Transplant. 2022 10; 36(10):e14630. . View in PubMed

The use of nondirected donor organs in living donor liver transplantation: Perspectives and guidance Hepatology. 2022 06; 75(6):1579-1589. . View in PubMed

Arterio-Biliary Fistula: a Rare Cause of Hemobilia J Gastrointest Surg. 2022 06; 26(6):1338-1339. . View in PubMed

Clinical Value of Surveillance Biopsies in Pediatric Liver Transplantation Liver Transpl. 2022 05; 28(5):843-854. . View in PubMed

A Programmatic Response, Including Bamlanivimab or Casirivimab-imdevimab Administration, Reduces Hospitalization and Death in COVID-19 Positive Abdominal Transplant Recipients Transplantation. 2022 02 01; 106(2):e153-e157. . View in PubMed

Anonymous Nondirected Living Liver Donation in the United States Transplant Direct. 2022 Jan; 8(1):e1275. . View in PubMed

Long-Term Suitability of Left Gastric Artery Inflow for Arterial Perfusion of Living Donor Right Lobe Grafts Case Rep Transplant. 2022; 2022:9421648. . View in PubMed

Adaptation of Imaging Mass Cytometry to Explore the Single Cell Alloimmune Landscape of Liver Transplant Rejection Front Immunol. 2022; 13:831103. . View in PubMed

Independent Assessment of the Children's Hepatic Tumors International Collaboration Risk Stratification for Hepatoblastoma and the Association of Tumor Histological Characteristics With Prognosis JAMA Netw Open. 2022 02 01; 5(2):e2148013. . View in PubMed

Non-invasive biomarkers of Fontan-associated liver disease JHEP Rep. 2021 Dec; 3(6):100362. . View in PubMed

Transfusion-free Retransplantation for Post-liver Transplantation Hepatic Artery Thrombosis: How Much Augmentation Is Too Much? Transplant Direct. 2021 Nov; 7(11):e776.. View in PubMed

Assessment of the global practice of living donor liver transplantation Transpl Int. 2021 Oct; 34(10):1914-1927. . View in PubMed

A Comparative Efficacy Evaluation of Recombinant Topical Thrombin (RECOTHROM®) With A Gelatin Sponge Carrier Versus Topical Oxidized Regenerated Cellulose (TABOTAMP®/SURGICEL®) In A Porcine Liver Bleeding Model J Invest Surg. 2021 Aug; 34(8):862-868. . View in PubMed

Review of Oncology and Transplant Literature for the Management of Hepatic and Pancreatic Resections in Jehovah's Witnesses Cancer Med J. 2021 Apr 01; 4(1):16-26. . View in PubMed

Effect of COVID-19 on Surgical Training Across the United States: A National Survey of General Surgery Residents J Surg Educ. 2021 Mar-Apr; 78(2):431-439. . View in PubMed

Potential association between public medical insurance, waitlist mortality, and utilization of living donor liver transplantation: An analysis of the Scientific Registry of Transplant Recipients Clin Transplant. 2021 10; 35(10):e14418. . View in PubMed

Re: Manuscript titled, "Liver transplantation for sickle cell disease: a systematic review" HPB (Oxford). 2021 07; 23(7):1135. . View in PubMed

Surgical shunts for extrahepatic portal vein obstruction in pediatric patients: a systematic review HPB (Oxford). 2021 05; 23(5):656-665. . View in PubMed

Health-related quality of life after anonymous nondirected living liver donation: A multicenter collaboration Am J Transplant. 2021 03; 21(3):1056-1067. . View in PubMed

Biliary Internal Stents and Biliary Complications in Adult Liver Transplantation Transplant Proc. 2021 Jan-Feb; 53(1):171-176. . View in PubMed

Intraoperative salvage and liver re-transplantation on ECMO Curr Opin Organ Transplant. 2021 08 01; 26(4):456-457. . View in PubMed

Ann Surg. 2021 12 01; 274(6):1032-1042. . View in PubMed

Clinicopathologic Characteristics of Late Acute Antibody-mediated Rejection in Pediatric Liver Transplantation Transplantation. 2021 09 01; 105(9):2045-2053. . View in PubMed

Hepatectomy for Breast Cancer Metastasis and Sarcoma are more likely to have Adverse Outcomes than Hepatectomy for Primary Hepatocellular Cancer or for Colorectal Metastasis Cancer Med J. 2020 Nov; 3(Suppl 1):6-12. . View in PubMed

Effects of Coronavirus Disease 2019 on Solid Organ Transplantation Transplant Proc. 2020 Nov; 52(9):2642-2653. . View in PubMed

A Potential Role for Robotic Cholecystectomy in Patients with Advanced Liver Disease: Analysis of the NSQIP Database Am Surg. 2020 Apr 01; 86(4):341-345. . View in PubMed

Living donor financial assistance programs in liver transplantation: The global perspective Clin Transplant. 2020 11; 34(11):e14073. . View in PubMed

Liver Transplantation in Patients with Sickle Cell Disease in the United States J Surg Res. 2020 11; 255:23-32. . View in PubMed

Long-Term Financial, Psychosocial, and Overall Health-Related Quality of Life After Living Liver Donation J Surg Res. 2020 09; 253:41-52. . View in PubMed

The need for a living donor wellness program Curr Opin Organ Transplant. 2020 08; 25(4):311-315. . View in PubMed

Hepatic Compartment Syndrome After a Right-sided Diaphragm Plication Ann Thorac Surg. 2020 06; 109(6):e425-e427. . View in PubMed

Global experience and perspective on anonymous nondirected live donation in living donor liver transplantation Clin Transplant. 2020 04; 34(4):e13836. . View in PubMed

Should living donor liver transplant selection be subject to the same restrictions as deceased donor transplant? Curr Opin Organ Transplant. 2020 02; 25(1):47-51.. View in PubMed

SPOT GRADE II: Clinical Validation of a New Method for Reproducibly Quantifying Surgical Wound Bleeding: Prospective, Multicenter, Multispecialty, Single-Arm Study Clin Appl Thromb Hemost. 2020 Jan-Dec; 26:1076029620936340. . View in PubMed

Severe Late-Onset Acute Cellular Rejection in a Pediatric Patient With Isolated Small Intestinal Transplant Rescued With Aggressive Immunosuppressive Approach: A Case Report Transplant Proc. 2019 Nov; 51(9):3181-3185. . View in PubMed

Outcomes of Liver Transplantation in Patients on Renal Replacement Therapy: Considerations for Simultaneous Liver Kidney Transplantation Versus Safety Net Transplant Direct. 2019 Oct; 5(10):e490. . View in PubMed

Immunologic benefit of maternal donors in pediatric living donor liver transplantation Pediatr Transplant. 2019 11; 23(7):e13560. . View in PubMed

Use of Donation after Cardiac Death Donors at the University of Southern California J Am Coll Surg. 2019 10; 229(4):437-438. . View in PubMed

Transplantation. 2019 04; 103(4):747-754. . View in PubMed

Variability in intensive care unit length of stay after liver transplant: Determinants and potential opportunities for improvement J Crit Care. 2019 04; 50:296-302. . View in PubMed

Chronically Retained Central Venous Catheter in Deceased Donor Liver Allograft Case Rep Transplant. 2019; 2019:4359197. . View in PubMed

Hepatorenal Syndrome Clin J Am Soc Nephrol. 2019 05 07; 14(5):774-781. . View in PubMed

Differentiation Therapy Targeting the ß-Catenin/CBP Interaction in Pancreatic Cancer Cancers (Basel). 2018 Mar 29; 10(4). . View in PubMed

Case series and systematic review of acquired diaphragmatic hernia after liver transplantation Pediatr Transplant. 2018 12; 22(8):e13296. . View in PubMed

The Increasingly Limited Basis for Portal Venous Pressure Modulation in Living Donor Liver Transplantation Liver Transpl. 2018 11; 24(11):1506-1507. . View in PubMed

Acute Kidney Injury After Liver Transplantation Transplantation. 2018 10; 102(10):1636-1649. . View in PubMed

Living donor liver transplantation: post-operative imaging follow-up of right lobe liver donors Abdom Radiol (NY). 2018 10; 43(10):2673-2678. . View in PubMed

De novo hepatocellular carcinoma post-multivisceral transplantation in a child Pediatr Transplant. 2017 11; 21(7). . View in PubMed

Inequity in organ allocation for patients awaiting liver transplantation: Rationale for uncapping the model for end-stage liver disease J Hepatol. 2017 09; 67(3):517-525. . View in PubMed

Effects of recipient size and allograft type on pediatric liver transplantation for biliary atresia Liver Transpl. 2017 02; 23(2):221-233. . View in PubMed

Perioperative Renal Replacement Therapy in Liver Transplantation Int Anesthesiol Clin. 2017; 55(2):81-91. . View in PubMed

Corrigendum to "Management of the critically ill patients with cirrhosis: A multidisciplinary perspective" J Hepatol. 2016 May 27. . View in PubMed

Orthotopic liver transplant for multifocal lymphangioendotheliomatosis with thrombocytopenia Pediatr Transplant. 2016 May; 20(3):456-9. . View in PubMed

Management of the critically ill patient with cirrhosis: A multidisciplinary perspective J Hepatol. 2016 Mar; 64(3):717-35. . View in PubMed

Fibrin Sealant Patch (TachoSil) vs Oxidized Regenerated Cellulose Patch (Surgicel Original) for the Secondary Treatment of Local Bleeding in Patients Undergoing Hepatic Resection: A Randomized Controlled Trial J Am Coll Surg. 2016 Mar; 222(3):261-8. . View in PubMed

Liver Condition and Resection: In reply to Toro and colleagues J Am Coll Surg. 2016 10; 223(4):678. . View in PubMed

Secondary Treatment of Local Bleeding in Patients Undergoing Hepatic Resection: In reply to Sugimachi J Am Coll Surg. 2016 08; 223(2):419-20. . View in PubMed

A multicenter study of 30 days complications after deceased donor liver transplantation in the model for end-stage liver disease score era Liver Transpl. 2015 Sep; 21(9):1160-8. . View in PubMed

Hepatoblastoma in a patient with methylmalonic aciduria Am J Med Genet A. 2015 Mar; 167A(3):635-8. . View in PubMed

Effect of neoadjuvant chemotherapy on resectability of stage III and IV hepatoblastoma Br J Surg. 2015 Jan; 102(1):108-13. . View in PubMed

Hepatopulmonary syndrome associated with nodular regenerative hyperplasia after liver transplantation in a child Pediatr Transplant. 2014 Aug; 18(5):E157-60. . View in PubMed

Intraoperative hemodialysis during liver transplantation: a decade of experience Liver Transpl. 2014 Jul; 20(7):756-64. . View in PubMed

Trisectionectomy for cholangiocarcinoma: is it worth it? Am Surg. 2014 Jun; 80(6):544-8.. View in PubMed

Combined surgical resection and radiofrequency ablation as treatment for metastatic ocular melanoma Surg Today. 2013 Apr; 43(4):367-71. . View in PubMed

Outcomes after liver transplantation in patients achieving a model for end-stage liver disease score of 40 or higher Transplantation. 2013 Feb 15; 95(3):507-12. . View in PubMed

Simultaneous liver-kidney transplantation: a survey of US transplant centers Am J Transplant. 2012 Nov; 12(11):3119-27. . View in PubMed

Simultaneous liver-kidney transplantation summit: current state and future directions Am J Transplant. 2012 Nov; 12(11):2901-8. . View in PubMed

Impact of the etiology of acute kidney injury on outcomes following liver transplantation: acute tubular necrosis versus hepatorenal syndrome Liver Transpl. 2012 May; 18(5):539-48. . View in PubMed

Colonic venous malformation and portal hypertension: association, management, and review of the literature Pediatr Surg Int. 2012 Apr; 28(4):435-8. . View in PubMed

The surgical management of pancreatic cancer Gastroenterol Clin North Am. 2012 Mar; 41(1):211-21. . View in PubMed

Hepatorenal syndrome: the 8th International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group Crit Care. 2012 Feb 09; 16(1):R23. . View in PubMed

Medical management of hepatorenal syndrome Nephrol Dial Transplant. 2012 Jan; 27(1):34-41. . View in PubMed

Working Party proposal for a revised classification system of renal dysfunction in patients with cirrhosis Gut. 2011 May; 60(5):702-9. . View in PubMed

Removal of a large hepatic neuroendocrine tumor causing Budd-Chiari syndrome using a median sternotomy approach in conjunction with a midline laparotomy incision Am Surg. 2011 Feb; 77(2):E27-9. . View in PubMed

Alternate method to secure the aorta for organ perfusion in donation after cardiac death donors Transpl Int. 2008 Dec; 21(12):1190-1. . View in PubMed

Intraoperative umbilical herniorrhaphy during liver transplantation Surgery. 2008 Mar; 143(3):451-2. . View in PubMed

Ischemic mass effect from biliary surgical clips J Laparoendosc Adv Surg Tech A. 2008 Feb; 18(1):84-7. . View in PubMed

A phase 3, randomized, double-blind comparative study of the efficacy and safety of topical recombinant human thrombin and bovine thrombin in surgical hemostasis J Am Coll Surg. 2007 Aug; 205(2):256-65. . View in PubMed

Living related donor nephrectomy in transfusion refusing donors Transpl Int. 2007 Jun; 20(6):490-6. . View in PubMed

Gallbladder mass with a carbohydrate antigen 19-9 level in the thousands: malignant or benign pathology? Report of a case. Surg Today. 2007; 37(4):342-4.. View in PubMed

Utility versus utilization of DCD liver allografts Am J Transplant. 2007 Jan; 7(1):263. . View in PubMed

Extended pancreatectomy with resection of the celiac axis: the modified Appleby operation Am J Surg. 2006 Sep; 192(3):330-5. . View in PubMed

Impact of a transfusion-free program on non-Jehovah's Witness patients undergoing liver transplantation Arch Surg. 2006 Sep; 141(9):913-7. . View in PubMed

Expanding the donor kidney pool: utility of renal allografts procured in a setting of uncontrolled cardiac death Am J Transplant. 2006 Jul; 6(7):1682-8. . View in PubMed

Gallstone-induced inflammatory fibrosis: a relentless clinical course of retained gallstones after laparoscopic cholecystectomy Am Surg. 2006 Apr; 72(4):303-6. . View in PubMed

Risk factors for graft survival after liver transplantation from donation after cardiac death donors: an analysis of OPTN/UNOS data Am J Transplant. 2006 Apr; 6(4):791-6. . View in PubMed

A comparison of sirolimus vscalcineurin inhibitor-based immunosuppressive therapies in liver transplantation. Aliment Pharmacol Ther. 2006 Feb 15; 23(4):513-20. . View in PubMed

Caval preservation with reconstruction of the hepatic veins using caval-common iliac bifurcation graft for domino liver transplantation Liver Transpl. 2006 Feb; 12(2):324-5. . View in PubMed

Iatrogenic pseudoaneurysms of the extrahepatic arterial vasculature: management and outcome HPB (Oxford). 2006; 8(6):458-64. . View in PubMed

Pancreaticoduodenectomy in adults with congenital intestinal rotation disorders Pancreas. 2005 Nov; 31(4):413-5. . View in PubMed

Transfusion free surgery: single institution experience of 27 consecutive liver transplants in Jehovah's Witnesses J Am Coll Surg. 2005 Sep; 201(3):412-7. . View in PubMed

To do or not to do living donor hepatectomy in Jehovah's Witnesses: single institution experience of the first 13 resections Am J Transplant. 2005 May; 5(5):1141-5. . View in PubMed

Transfusion-free techniques in pediatric live donor liver transplantation J Pediatr Gastroenterol Nutr. 2005 Apr; 40(4):521-3. . View in PubMed

Major hepatobiliary surgery during pregnancy: safety and timing Am Surg. 2005 Apr; 71(4):354-8. . View in PubMed

Optimal cytoreduction after combined resection and radiofrequency ablation of hepatic metastases from recurrent malignant ovarian tumors Gynecol Oncol. 2005 Apr; 97(1):266-70. . View in PubMed

Recombinant human coagulation factor VIIa in Jehovah's Witness patients undergoing liver transplantation Am Surg. 2005 Feb; 71(2):175-9. . View in PubMed

Live donor liver transplantation without blood products: strategies developed for Jehovah's Witnesses offer broad application Ann Surg. 2004 Aug; 240(2):350-7. . View in PubMed

Unusual cases of jaundice secondary to non-neoplastic bile duct obstruction Am Surg. 2004 Jul; 70(7):620-4. . View in PubMed

Gastroduodenal artery pseudoaneurysm secondary to pancreatic head biopsy J Ultrasound Med. 2004 Jul; 23(7):997-1001. . View in PubMed

Management of an abdominal aortic aneurysm in a patient with end-stage liver disease Am J Transplant. 2004 Apr; 4(4):666-8. . View in PubMed

Rapid intravenous desensitization to antithymocyte globulin in a patient with aplastic anemia Transplantation. 2004 Jan 27; 77(2):321-3. . View in PubMed

Live donor liver transplantation: staging hepatectomy in a Jehovah's Witness recipient J Hepatobiliary Pancreat Surg. 2004; 11(3):211-4. . View in PubMed

Left portahepatic shunt: a novel technique to decrease excessive portal venous inflow during live donor liver transplantation J Am Coll Surg. 2003 Dec; 197(6):1056-7. . View in PubMed

Characteristics and management of splenic artery aneurysm in liver transplant candidates and recipients Am Surg. 2003 Nov; 69(11):933-40. . View in PubMed

Comparison of outcomes in noncomplicated and in higher-risk donors after standard versus hand-assisted laparoscopic nephrectomy Am Surg. 2003 Sep; 69(9):771-8. . View in PubMed

Restricting fresh frozen plasma in hepatic resections J Am Coll Surg. 2003 Aug; 197(2):339-40. . View in PubMed

Liver transplantation in cystic fibrosis Curr Opin Pulm Med. 2001 Nov; 7(6):441-7. . View in PubMed

Live-donor liver transplantation: the USC experience Acta Chir Belg. 2001 Sep-Oct; 101(5):220-3. . View in PubMed

Organs for transplantation N Engl J Med. 2000 Dec 07; 343(23):1731; author reply 1732. . View in PubMed

Treatment of tacrolimus-related adverse effects by conversion to cyclosporine in liver transplant recipients Transpl Int. 2000; 13(1):73-8. . View in PubMed

Successful transplantation of pediatric en bloc kidneys with bilateral double ureters Transpl Int. 1999; 12(4):281-2. . View in PubMed

Conversion to tacrolimus to ameliorate cyclosporine toxicity in kidney recipients Transplant Proc. 1998 Aug; 30(5):2030-2. . View in PubMed

Should pediatric donors younger than 2 years of age be used in kidney transplantation? Transplant Proc. 1997 Dec; 29(8):3276-7.. View in PubMed

Kidney transplantation utilizing donors from both age extremes Transplant Proc. 1997 Dec; 29(8):3655-6. . View in PubMed

Development of an in situ isolated porcine liver perfusion model for tightly controlled physiologic and pharmacologic studies J Invest Surg. 1996 Mar-Apr; 9(2):131-47. . View in PubMed

Hepatic artery pseudoaneurysm and hemobilia following laser laparoscopic cholecystectomyA case report. Surg Endosc. 1994 Mar; 8(3):201-4. . View in PubMed

A new rat model for studies of the ischemic injury after transplantation of fatty livers: improvement after postoperative administration of prostaglandin Transplantation. 1994 Feb; 57(3):457-8. . View in PubMed

New technique of combined liver and kidney transplantation Transplant Proc. 1989 Feb; 21(1 Pt 2):2381-2. . View in PubMed

Dr. Genyk a professor of clinical surgery at the USC School of Medicine and the Division of Hepatobiliary/Pancreatic and Abdominal Organ Transplant Surgery. Additionally, he is an attending surgeon at Children’s Hospital of Los Angeles (CHLA). Dr. Genyk graduated with honors from Ivano-Frankivk’s Medical Institute in Ukraine. He received his postgraduate medical and research training at Baylor University Medical Center in Dallas, Texas, University of Alabama at Birmingham Medical Center and Mount Sinai Medical Center in New York City. He is an expert in living-related donor liver transplantation, adult and pediatric liver transplantation, laparoscopic donor nephrectomy for kidney transplantation, pancreas transplantation as well as non-transplant hepatobiliary and pancreatic surgery. Shortly after Dr. Genyk joined the USC faculty, the USC Liver Transplant Team pioneered living-related donor liver transplantation at CHLA and Keck Hospital of USC. Dr. Genyk is board certified in general surgery and ASTS certified in transplantation surgery. He is associate director of Abdominal Organ Transplant and surgical director of Living Donor Liver Transplant Program at USCUH, as well as surgical director of Pediatric Liver/Intestinal Transplant Program at CHLA. His research interests include innovations in live donor liver transplantation, new approaches to surgical treatment of extensive tumors of liver and pancreas, minimally invasive surgery for hepatobiliary and pancreatic diseases, liver regeneration and immunological tolerance in transplantation.
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