Aarti Jain

Clinical Assistant Professor of Emergency Medicine (Clinician Educator)

Assistant Program Director

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Publications

  • Broad antibody and T cell responses to Ebola, Sudan, and Bundibugyo ebolaviruses using mono- and multi-valent adjuvanted glycoprotein vaccines Antiviral Res. 2024 Mar 06; 105851. . View in PubMed
  • Impact of sex on humoral immunity with live influenza B virus vaccines in mice NPJ Vaccines. 2024 Feb 26; 9(1):45. . View in PubMed
  • Profiling the antibody response of humans protected by immunization with Plasmodium vivax radiation-attenuated sporozoites Sci Rep. 2024 02 02; 14(1):2790. . View in PubMed
  • Risk factors for SARS-CoV-2 seropositivity in a health care worker population during the early pandemic BMC Infect Dis. 2023 May 16; 23(1):330. . View in PubMed
  • Protein Nanoparticle-Mediated Delivery of Recombinant Influenza Hemagglutinin Enhances Immunogenicity and Breadth of the Antibody Response ACS Infect Dis. 2023 02 10; 9(2):239-252. . View in PubMed
  • Multivalent vaccines demonstrate immunogenicity and protect against Coxiella burnetii aerosol challenge Front Immunol. 2023; 14:1192821. . View in PubMed
  • Engineering Protein Nanoparticles Functionalized with an Immunodominant Coxiella burnetii Antigen to Generate a Q Fever Vaccine Bioconjug Chem. 2023 09 20; 34(9):1653-1666. . View in PubMed
  • Influenza vaccine format mediates distinct cellular and antibody responses in human immune organoidsImmunity. 2023 08 08; 56(8):1910-1926. e7. . View in PubMed
  • Analysis and comparison of SARS-CoV-2 variant antibodies and neutralizing activity for 6 months after a booster mRNA vaccine in a healthcare worker population Res Sq. 2022 Dec 14. . View in PubMed
  • The antibody landscapes following AS03 and MF59 adjuvanted H5N1 vaccination NPJ Vaccines. 2022 Aug 30; 7(1):103. . View in PubMed
  • Cognitive load during training for out-of-department emergency responses AEM Educ Train. 2022 Jun; 6(3):e10742. . View in PubMed
  • “Everybody in this room can understand”: A qualitative exploration of peer support during residency training AEM Educ Train. 2022 Apr; 6(2):e10728. . View in PubMed
  • Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity had no antiviral effects but moderately reduced lung inflammation PLoS Pathog. 2022 04; 18(4):e1009925. . View in PubMed
  • Magnitude and breadth of antibody cross-reactivity induced by recombinant influenza hemagglutinin trimer vaccine is enhanced by combination adjuvants Sci Rep. 2022 06 02; 12(1):9198. . View in PubMed
  • Virtual Open House: Incorporating Support Persons into the Residency Community West J Emerg Med. 2022 12 21; 24(1):79-82. . View in PubMed
  • Protein Microarrays as a Tool to Analyze Antibody Responses to Variant Surface Antigens Expressed on the Surface of Plasmodium falciparum-Infected Erythrocytes Methods Mol Biol. 2022; 2470:343-358. . View in PubMed
  • Centrifugal disc liquid reciprocation flow considerations for antibody binding to COVID antigen array during microfluidic integration Lab Chip. 2022 07 12; 22(14):2695-2706. . View in PubMed
  • Persistence of SARS-CoV-2 Antibodies in Vaccinated Health Care Workers Analyzed by Coronavirus Antigen Microarray Front Immunol. 2022; 13:817345. . View in PubMed
  • Distinct SARS-CoV-2 antibody reactivity patterns elicited by natural infection and mRNA vaccination NPJ Vaccines. 2021 Nov 04; 6(1):132. . View in PubMed
  • Antibody signatures of asymptomatic Plasmodium falciparum malaria infections measured from dried blood spots Malar J. 2021 Sep 23; 20(1):378. . View in PubMed
  • Immunoprofiles associated with controlled human malaria infection and naturally acquired immunity identify a shared IgA pre-erythrocytic immunoproteome NPJ Vaccines. 2021 Sep 13; 6(1):115. . View in PubMed
  • Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity reduces lung inflammation bioRxiv. 2021 Sep 01. . View in PubMed
  • FluB-RAM and FluB-RANS: Genome Rearrangement as Safe and Efficacious Live Attenuated Influenza B Virus Vaccines Vaccines (Basel). 2021 Aug 12; 9(8). . View in PubMed
  • “I Have Nothing Else to Give”: A Qualitative Exploration of Emergency Medicine Residents’ Perceptions of Burnout Teach Learn Med. 2021 Aug-Sep; 33(4):407-415. . View in PubMed
  • Development of a Novel Live Attenuated Influenza A Virus Vaccine Encoding the IgA-Inducing Protein Vaccines (Basel). 2021 Jun 27; 9(7). . View in PubMed
  • Predicting COVID-19 Severity with a Specific Nucleocapsid Antibody plus Disease Risk Factor Score bioRxiv. 2021 Mar 08. . View in PubMed
  • Modeling human adaptive immune responses with tonsil organoids Nat Med. 2021 01; 27(1):125-135. . View in PubMed
  • Administration of Multivalent Influenza Virus Recombinant Hemagglutinin Vaccine in Combination-Adjuvant Elicits Broad Reactivity Beyond the Vaccine Components Front Immunol. 2021; 12:692151. . View in PubMed
  • Infection prevention strategies are highly protective in COVID-19 units while main risks to healthcare professionals come from coworkers and the community Antimicrob Resist Infect Control. 2021 11 22; 10(1):163. . View in PubMed
  • Predicting COVID-19 Severity with a Specific Nucleocapsid Antibody plus Disease Risk Factor Score mSphere. 2021 04 28; 6(2). . View in PubMed
  • Distinct SARS-CoV-2 antibody reactivity patterns in coronavirus convalescent plasma revealed by a coronavirus antigen microarray Sci Rep. 2021 04 06; 11(1):7554. . View in PubMed
  • Analysis of SARS-CoV-2 antibodies in COVID-19 convalescent blood using a coronavirus antigen microarray Nat Commun. 2021 01 04; 12(1):6. . View in PubMed
  • Protein Arrays for the Identification of Seroreactive Protein Markers for Infectious Diseases Methods Mol Biol. 2021; 2344:139-150. . View in PubMed
  • A Modular Microarray Imaging System for Highly Specific COVID-19 Antibody Testing bioRxiv. 2020 May 23. . View in PubMed
  • Analysis of SARS-CoV-2 Antibodies in COVID-19 Convalescent Blood using a Coronavirus Antigen Microarray bioRxiv. 2020 May 08. . View in PubMed
  • Analysis of Serologic Cross-Reactivity Between Common Human Coronaviruses and SARS-CoV-2 Using Coronavirus Antigen Microarray bioRxiv. 2020 Mar 25. . View in PubMed
  • Tuning Subunit Vaccines with Novel TLR Triagonist Adjuvants to Generate Protective Immune Responses against Coxiella burnetii J Immunol. 2020 02 01; 204(3):611-621. . View in PubMed
  • A modular microarray imaging system for highly specific COVID-19 antibody testing Lab Chip. 2020 09 21; 20(18):3302-3309. . View in PubMed
  • Which Emergency Medicine Milestone Sub-competencies are Identified Through Narrative Assessments? West J Emerg Med. 2019 Dec 20; 21(1):173-179.. View in PubMed
  • Linked Toll-Like Receptor Triagonists Stimulate Distinct, Combination-Dependent Innate Immune Responses ACS Cent Sci. 2019 Jul 24; 5(7):1137-1145. . View in PubMed
  • Hospital-derived antibody profiles of malaria patients in Southwest India Malar J. 2019 Apr 17; 18(1):138. . View in PubMed
  • Distinct Antibody Signatures Associated with Different Malaria Transmission Intensities in Zambia and Zimbabwe mSphere. 2019 03 27; 4(2). . View in PubMed
  • Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes J Vis Exp. 2019 07 26; (149). . View in PubMed
  • Antibody Biomarkers Associated with Sterile Protection Induced by Controlled Human Malaria Infection under Chloroquine Prophylaxis mSphere. 2019 02 20; 4(1). . View in PubMed
  • Discovery of new Toxoplasma gondii antigenic proteins using a high throughput protein microarray approach screening sera of murine model infected orally with oocysts and tissue cysts Parasit Vectors. 2018 Jul 04; 11(1):393. . View in PubMed
  • Antibody Profiling by Proteome Microarray with Multiplex Isotype Detection Reveals Overlap between Human and Aotus nancymaae Controlled Malaria Infections Proteomics. 2018 07; 18(13):e1870115. . View in PubMed
  • Protein-Specific Features Associated with Variability in Human Antibody Responses to Plasmodium falciparum Malaria Antigens Am J Trop Med Hyg. 2018 01; 98(1):57-66. . View in PubMed
  • Antibody Profiling by Proteome Microarray with Multiplex Isotype Detection Reveals Overlap between Human and Aotus nancymaae Controlled Malaria Infections Proteomics. 2018 01; 18(2). . View in PubMed
  • Protein Microarray Analysis of the Specificity and Cross-Reactivity of Influenza Virus Hemagglutinin-Specific Antibodies mSphere. 2018 12 12; 3(6). . View in PubMed
  • Development of ELISAs for diagnosis of acute typhoid fever in Nigerian children PLoS Negl Trop Dis. 2017 Jun; 11(6):e0005679. . View in PubMed
  • Saved by the Bougie Ann Emerg Med. 2017 10; 70(4):479-482. . View in PubMed
  • Characterizing Antibody Responses to Plasmodium vivax and Plasmodium falciparum Antigens in India Using Genome-Scale Protein Microarrays PLoS Negl Trop Dis. 2017 01; 11(1):e0005323. . View in PubMed
  • Treatment of Chronic Asymptomatic Plasmodium falciparum Infection Does Not Increase the Risk of Clinical Malaria Upon Reinfection Clin Infect Dis. 2017 03 01; 64(5):645-653. . View in PubMed
  • Evaluation of quantum dot immunofluorescence and a digital CMOS imaging system as an alternative to conventional organic fluorescence dyes and laser scanning for quantifying protein microarrays Proteomics. 2016 Apr; 16(8):1271-9. . View in PubMed
  • Antibody Profiling in Naïve and Semi-immune Individuals Experimentally Challenged with Plasmodium vivax Sporozoites PLoS Negl Trop Dis. 2016 Mar; 10(3):e0004563. . View in PubMed
  • Common asymptomatic and submicroscopic malaria infections in Western Thailand revealed in longitudinal molecular and serological studies: a challenge to malaria elimination Malar J. 2016 06 22; 15:333. . View in PubMed
  • Serodiagnosis of Acute Typhoid Fever in Nigerian Pediatric Cases by Detection of Serum IgA and IgG Against Hemolysin E and Lipopolysaccharide Am J Trop Med Hyg. 2016 08 03; 95(2):431-9. . View in PubMed
  • Circulating Th1-Cell-type Tfh Cells that Exhibit Impaired B Cell Help Are Preferentially Activated during Acute Malaria in Children Cell Rep. 2015 Oct 13; 13(2):425-39. . View in PubMed
  • Genetic Resistance to Malaria Is Associated With Greater Enhancement of Immunoglobulin (Ig)M Than IgG Responses to a Broad Array of Plasmodium falciparum Antigens Open Forum Infect Dis. 2015 Sep; 2(3):ofv118. . View in PubMed
  • Biosignatures of Exposure/Transmission and Immunity Am J Trop Med Hyg. 2015 Sep; 93(3 Suppl):16-27. . View in PubMed
  • Identification of Toxoplasma gondii antigens associated with different types of infection by serum antibody profiling Parasitology. 2015 May; 142(6):827-38. . View in PubMed
  • Submicroscopic and asymptomatic Plasmodium falciparum and Plasmodium vivax infections are common in western Thailand – molecular and serological evidence Malar J. 2015 Feb 25; 14:95. . View in PubMed
  • T cell antigen discovery using soluble vaccinia proteome reveals recognition of antigens with both virion and nonvirion association J Immunol. 2014 Aug 15; 193(4):1812-27. . View in PubMed
  • Pre-erythrocytic antibody profiles induced by controlled human malaria infections in healthy volunteers under chloroquine prophylaxis Sci Rep. 2013 Dec 19; 3:3549. . View in PubMed
  • Profiling the humoral immune response of acute and chronic Q fever by protein microarrayMol Cell Proteomics. 2011 Oct; 10(10):M110. 006304. . View in PubMed
  • Identification of the feline humoral immune response to Bartonella henselae infection by protein microarray PLoS One. 2010 Jul 06; 5(7):e11447. . View in PubMed