Faculty

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Brett Thomas Lund, PhD
Assistant Professor of Research Neurology
Neurology
MCH 246 Health Sciences Campus Los Angeles
+1 323 442 3079

Overview

Dr. Lund received an honors degree in Biochemistry from the University of Dundee, Scotland in 1990 and a Ph.D. in Veterinary Immunology and Pathology from the Royal “Dick” Veterinary College at the University of Edinburgh, Scotland in 1994. He trained with world-renowned immunologists during his post-doctoral fellowship in viral immunology from 1994-1997 at the BBSRC Institute for Animal Health. Dr. Lund was recruited to the USC Department of Neurology as a senior research fellow in 1997 to the study efficacy of a novel vaccine for the treatment of multiple sclerosis. In 1999 Dr. Lund was appointed to the faculty in the Department of Neurology at USC as a visiting Assistant Professor and was subsequently appointed as Assistant Professor in 2004.

Dr. Lund’s research primarily focuses on the role of the immune system, not only in the pathogenesis and accrual of pathology in the central nervous system, but also in tissue repair and neuroplasticity. His work is conducted both in animal models of disease and in MS patients. Current research includes assessing the potential role of the renin-angiotensin system on disease progression in MS and animal models, and in collaboration with faculty in the school of pharmacy and the school of medicine assessing the capacity of therapeutic intervention by manipulating the protective arm of this critical biological system. Dr. Lund is also assessing the effect of exercise in disease prevention and recovery, testing the possibility that exercise alters immune status to be more neuroprotective and less damaging. Dr. Lund is also actively involved in numerous clinical trials and studies with colleagues at USC, assessing possible modes of action of new and approved MS therapies, and studying the effects of MS drugs on the immune system in MS patients.

The National Multiple Sclerosis Society, US Department of Defense, USC-CTSI, numerous pharmaceutical companies and private foundations have supported Dr. Lund’s research. He is a member of the British Society for Immunology, the Society for General Microbiology and the Federation of Clinical Immunology Societies and serves as a member of the University of Southern California, Radiation Safety Committee and the Institutional Animal Care and Use Committee.

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