Faculty

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Deepa Bhojwani, MBBS, DCH
Associate Professor of Clinical Pediatrics
Pediatrics
CHLA 4650 W. Sunset Blvd. Off Campus Los Angeles

Publications

A neoplasm with FIP1L1-PDGFRA fusion presenting as pediatric T-cell lymphoblastic leukemia/lymphoma without eosinophilia. Cancer Genet. 2017 Oct; 216-217:91-99. View in: PubMed

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The PI3Kd Inhibitor Idelalisib Inhibits Homing in an in Vitro and in Vivo Model of B ALL. Cancers (Basel). 2017 Sep 10; 9(9). View in: PubMed

Association of clinical trial enrollment and survival using contemporary therapy for pediatric acute lymphoblastic leukemia. Pediatr Blood Cancer. 2017 Sep 06. View in: PubMed

Phase I Study of the anti-CD22 immunotoxin moxetumomab pasudotox for childhood acute lymphoblastic leukemia. Blood. 2017 Aug 09. View in: PubMed

Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP. Genome Res. 2017 Feb; 27(2):185-195. View in: PubMed

Phase I/Phase II Study of Blinatumomab in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia. J Clin Oncol. 2016 Dec 20; 34(36):4381-4389. View in: PubMed

Intravitreal dexamethasone implant for recurrent cystoid macular edema due to Irvine-Gass syndrome: a prospective case series. Eye (Lond). 2016 Dec; 30(12):1549-1557. View in: PubMed

Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP. Genome Res. 2016 Nov 30. View in: PubMed

Leukoencephalopathy and long-term neurobehavioural, neurocognitive, and brain imaging outcomes in survivors of childhood acute lymphoblastic leukaemia treated with chemotherapy: a longitudinal analysis. Lancet Haematol. 2016 Oct; 3(10):e456-e466. View in: PubMed

The Role of Leukapheresis in the Current Management of Hyperleukocytosis in Newly Diagnosed Childhood Acute Lymphoblastic Leukemia. Pediatr Blood Cancer. 2016 Sep; 63(9):1546-51. View in: PubMed

Wyburn Mason Syndrome: A Rare Phacomatosis. Ophthalmology. 2016 Aug; 123(8):1787. View in: PubMed

NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity. Nat Genet. 2016 Apr; 48(4):367-73. View in: PubMed

Idiopathic bilateral uveal effusion syndrome (UES) in a middle-aged woman. Indian J Med Res. 2015 Nov; 142(5):623-4. View in: PubMed

In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs. Mayo Clin Proc. 2015 Aug; 90(8):996-1000. View in: PubMed

Giant nevus of Ota. Indian J Ophthalmol. 2015 Jun; 63(6):532-3. View in: PubMed

NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells. Nat Genet. 2015 Jun; 47(6):607-14. View in: PubMed

Clinical utility of sequential minimal residual disease measurements in the context of risk-based therapy in childhood acute lymphoblastic leukaemia: a prospective study. Lancet Oncol. 2015 Apr; 16(4):465-74. View in: PubMed

Bietti crystalline dystrophy in a young woman. JAMA Ophthalmol. 2015 Mar 12; 133(3):e143514. View in: PubMed

Bietti crystalline dystrophy in a young woman. JAMA Ophthalmol. 2015 Mar; 133(3):e143514. View in: PubMed

The role of FDG-PET/CT in the evaluation of residual disease in paediatric non-Hodgkin lymphoma. Br J Haematol. 2015 Mar; 168(6):845-53. View in: PubMed

Utility of early screening magnetic resonance imaging for extensive hip osteonecrosis in pediatric patients treated with glucocorticoids. J Clin Oncol. 2015 Feb 20; 33(6):610-5. View in: PubMed

Biology of childhood acute lymphoblastic leukemia. Pediatr Clin North Am. 2015 Feb; 62(1):47-60. View in: PubMed

A revised definition for cure of childhood acute lymphoblastic leukemia. Leukemia. 2014 Dec; 28(12):2336-43. View in: PubMed

Severe hypertriglyceridaemia during therapy for childhood acute lymphoblastic leukaemia. Eur J Cancer. 2014 Oct; 50(15):2685-94. View in: PubMed

How accurate is the diagnosis of diabetic retinopathy on telescreening? The Indian scenario. Rural Remote Health. 2014 Oct-Dec; 14(4):2809. View in: PubMed

Unilateral Punctate inner choroidopathy with choroidal neovascular membrane in a young male. Indian J Ophthalmol. 2014 Sep; 62(9):949-50. View in: PubMed

Systemic lupus erythematosus retinopathy in a 32-year-old female: report of a case. Indian J Ophthalmol. 2014 Sep; 62(9):951-2. View in: PubMed

A phase I study of EZN-3042, a novel survivin messenger ribonucleic acid (mRNA) antagonist, administered in combination with chemotherapy in children with relapsed acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium. J Pediatr Hematol Oncol. 2014 Aug; 36(6):458-63. View in: PubMed

Voriconazole plasma concentrations in immunocompromised pediatric patients vary by CYP2C19 diplotypes. Pharmacogenomics. 2014 Jun; 15(8):1065-78. View in: PubMed

Impact of tyrosine kinase inhibitors on minimal residual disease and outcome in childhood Philadelphia chromosome-positive acute lymphoblastic leukemia. Cancer. 2014 May 15; 120(10):1514-9. View in: PubMed

Methotrexate-induced neurotoxicity and leukoencephalopathy in childhood acute lymphoblastic leukemia. J Clin Oncol. 2014 Mar 20; 32(9):949-59. View in: PubMed

How accurate is the diagnosis of diabetic retinopathy on telescreening? The Indian scenario. How accurate is the diagnosis of diabetic retinopathy on telescreening? The Indian scenario. Rural Remote Health. 2014; 14(4):2809. View in: PubMed

Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse. Nat Genet. 2013 Dec; 45(12):1494-8. View in: PubMed

HMGA1 overexpression correlates with relapse in childhood B-lineage acute lymphoblastic leukemia. Leuk Lymphoma. 2013 Nov; 54(11):2565-7. View in: PubMed

Results of treatment of advanced-stage lymphoblastic lymphoma at St Jude Children's Research Hospital from 1962 to 2002. Ann Oncol. 2013 Sep; 24(9):2425-9. View in: PubMed

Genetic mediators of neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia. J Clin Oncol. 2013 Jun 10; 31(17):2182-8. View in: PubMed

Prognostic impact of absolute lymphocyte counts at the end of remission induction in childhood acute lymphoblastic leukemia. Cancer. 2013 Jun 01; 119(11):2061-6. View in: PubMed

Prognostic impact of absolute lymphocyte counts at the end of remission induction in childhood acute lymphoblastic leukemia. Cancer. 2013 Jun 1; 119(11):2061-6. View in: PubMed

Novel susceptibility variants at 10p12. 31-12. 2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. J Natl Cancer Inst. 2013 May 15; 105(10):733-42. View in: PubMed

Relapsed childhood acute lymphoblastic leukaemia. Lancet Oncol. 2013 May; 14(6):e205-17. View in: PubMed

Thiopurine S-methyltransferase pharmacogenetics in childhood acute lymphoblastic leukemia. Methods Mol Biol. 2013; 999:273-84. View in: PubMed

ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy. Leukemia. 2012 Feb; 26(2):265-70. View in: PubMed

Endogenous knockdown of survivin improves chemotherapeutic response in ALL models. Leukemia. 2012 Feb; 26(2):271-9. View in: PubMed

Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling. Blood. 2012 Jan 19; 119(3):817-25. View in: PubMed

Combination chemotherapy with clofarabine, cyclophosphamide, and etoposide in children with refractory or relapsed haematological malignancies. Br J Haematol. 2012 Jan; 156(2):275-9. View in: PubMed

Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies. Blood. 2011 Nov 10; 118(19):5218-26. View in: PubMed

Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles. Leukemia. 2011 Oct; 25(10):1555-63. View in: PubMed

Spinal epidural lipomatosis in children with hematologic malignancies. Ann Hematol. 2011 Sep; 90(9):1067-74. View in: PubMed

Improved prognosis for older adolescents with acute lymphoblastic leukemia. J Clin Oncol. 2011 Feb 1; 29(4):386-91. View in: PubMed

Improved prognosis for older adolescents with acute lymphoblastic leukemia. J Clin Oncol. 2011 Feb 01; 29(4):386-91. View in: PubMed

Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome. Blood. 2010 Dec 2; 116(23):4874-84. View in: PubMed

Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome. Blood. 2010 Dec 02; 116(23):4874-84. View in: PubMed

Cytotoxicity of the anti-CD22 immunotoxin HA22 (CAT-8015) against paediatric acute lymphoblastic leukaemia. Br J Haematol. 2010 Aug; 150(3):352-8. View in: PubMed

Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia. Blood. 2010 Feb 18; 115(7):1394-405. View in: PubMed

Long-term results of St Jude Total Therapy Studies 11, 12, 13A, 13B, and 14 for childhood acute lymphoblastic leukemia. Leukemia. 2010 Feb; 24(2):371-82. View in: PubMed

Intravenous zanamivir for oseltamivir-resistant 2009 H1N1 influenza. N Engl J Med. 2010 Jan 7; 362(1):88-9. View in: PubMed

Intravenous zanamivir for oseltamivir-resistant 2009 H1N1 influenza. N Engl J Med. 2010 Jan 07; 362(1):88-9. View in: PubMed

High-risk childhood acute lymphoblastic leukemia. Clin Lymphoma Myeloma. 2009; 9 Suppl 3:S222-30. View in: PubMed

Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia. Blood. 2008 Nov 15; 112(10):4178-83. View in: PubMed

Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: A Children's Oncology Group Study [corrected]. J Clin Oncol. 2008 Sep 20; 26(27):4376-84. View in: PubMed

T-cell PTLD presenting as acalculous cholecystitis. Pediatr Transplant. 2008 Sep; 12(6):717-20. View in: PubMed

Intrathecal liposomal cytarabine: more friend than foe? Leuk Lymphoma. Intrathecal liposomal cytarabine: more friend than foe? Leuk Lymphoma. 2008 Aug; 49(8):1427-30. View in: PubMed

Potential of gene expression profiling in the management of childhood acute lymphoblastic leukemia. Paediatr Drugs. 2007; 9(3):149-56. View in: PubMed

Gene expression profiling reveals intrinsic differences between T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma. Pediatr Blood Cancer. 2006 Aug; 47(2):130-40. View in: PubMed

Biologic pathways associated with relapse in childhood acute lymphoblastic leukemia: a Children's Oncology Group study. Blood. 2006 Jul 15; 108(2):711-7. View in: PubMed

Childhood acute lymphoblastic leukemia in the age of genomics. Pediatr Blood Cancer. 2006 May 01; 46(5):570-8. View in: PubMed

Childhood acute lymphoblastic leukemia in the age of genomics. Pediatr Blood Cancer. 2006 May 1; 46(5):570-8. View in: PubMed

Thrombophilia in childhood. Curr Probl Pediatr Adolesc Health Care. 2004 May-Jun; 34(5):190-212. View in: PubMed

Pediatric acute lymphoblastic leukemia. Hematology Am Soc Hematol Educ Program. 2003; 102-31. View in: PubMed

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