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Gene Yong Sung, MD

Assistant Professor of Clinical Neurology

Director of Neuro Critical Care

LAC+USC Medical Center Inpatient Chief

Image of Gene Yong Sung, MD
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Phone +1 323 409 8552
Email gsung@usc.edu
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Overview

Dr. Sung is Assistant Professor of Clinical Neurology and the Director of Neurocritical Care at LAC+USC. He is a recognized leader in both fields of stroke and neurocritical care. He was a founding member of both the international Neurocritical Care Society (and its current vice-President) and the Western States Stroke Consortium (and its current President). He is also a founder of the journal Neurocritical Care and its current associate editor. Furthermore, he has had leadership roles in many national organizations, including the American Academy of Neurology, American Stroke Association and the National Stroke Association and has published and reviewed articles for many journals and has been an invited lecturer in conference throughout the world.

Dr. Sung’s research interests include stroke outcomes, critical care management of stroke, intracranial pressure, cerebral reperfusion, and hypothermia. He is the principal investigator for several investigator-initiated and industry-sponsored translation research projects and he recently received funding to examine outcomes in telemedicine delivery of stroke care.

Publications

  • Association Between Body Mass Index and Functional Outcomes in Patients With Intracerebral Hemorrhage Neurology. 2024 Jan 23; 102(2):e208014. . View in PubMed
  • Immunonutrition with Omega-3 Fatty Acid Supplementation in Severe TBI: Retrospective Analysis of Patient Characteristics and Outcomes Res Sq. 2023 Nov 07. . View in PubMed
  • Can J Anaesth. 2023 04; 70(4):651-658. . View in PubMed
  • Brain Death/Death by Neurological Criteria: International Standardization and the World Brain Death Project Crit Care Clin. 2023 Jan; 39(1):215-219. . View in PubMed
  • Barriers to the Use of Neurologic Criteria to Declare Death in Africa Am J Hosp Palliat Care. 2022 Feb; 39(2):243-249. . View in PubMed
  • Risk Factors Associated With Mortality and Neurologic Disability After Intracerebral Hemorrhage in a Racially and Ethnically Diverse Cohort JAMA Netw Open. 2022 03 01; 5(3):e221103. . View in PubMed
  • Ancillary Testing for Determination of Death by Neurologic Criteria Around the World Neurocrit Care. 2021 04; 34(2):473-484. . View in PubMed
  • Author Response: Determination of Death by Neurologic Criteria Around the World Neurology. 2021 04 27; 96(17):826. . View in PubMed
  • Determination of Brain Death-Reply JAMA. 2021 02 02; 325(5):494. . View in PubMed
  • Author Response: Determination of Death by Neurologic Criteria Around the World Neurology. 2021 04 27; 96(17):827. . View in PubMed
  • Ethnic and Racial Variation in Intracerebral Hemorrhage Risk Factors and Risk Factor Burden JAMA Netw Open. 2021 08 02; 4(8):e2121921. . View in PubMed
  • Determination of Brain Death/Death by Neurologic Criteria: The World Brain Death Project JAMA. 2020 Sep 15; 324(11):1078-1097. . View in PubMed
  • Determination of Brain Death/Death by Neurologic Criteria in Countries in Asia and the Pacific J Clin Neurol. 2020 Jul; 16(3):480-490. . View in PubMed
  • Determination of death by neurologic criteria in Latin American and Caribbean countries Clin Neurol Neurosurg. 2020 10; 197:105953. . View in PubMed
  • Neurocritical Care Resource Utilization in Pandemics: A Statement by the Neurocritical Care Society Neurocrit Care. 2020 08; 33(1):13-19. . View in PubMed
  • Global Survey of Outcomes of Neurocritical Care Patients: Analysis of the PRINCE Study Part 2 Neurocrit Care. 2020 02; 32(1):88-103. . View in PubMed
  • Worldwide Organization of Neurocritical Care: Results from the PRINCE Study Part 1 Neurocrit Care. 2020 02; 32(1):172-179. . View in PubMed
  • Implementation of Targeted Temperature Management After Out-of-Hospital Cardiac Arrest: Observations From the Los Angeles County Regional System J Am Heart Assoc. 2020 12 15; 9(24):e016652. . View in PubMed
  • Determination of death by neurologic criteria around the world Neurology. 2020 07 21; 95(3):e299-e309. . View in PubMed
  • Targeted Temperature Management and Multimodality Monitoring of Comatose Patients After Cardiac Arrest Front Neurol. 2018; 9:768. . View in PubMed
  • Corrigendum: Targeted Temperature Management and Multimodality Monitoring of Comatose Patients After Cardiac Arrest Front Neurol. 2018; 9:877. . View in PubMed
  • Outcomes of ST Elevation Myocardial Infarction Complicated by Out-of-Hospital Cardiac Arrest (from the Los Angeles County Regional System) Am J Cardiol. 2017 Sep 01; 120(5):729-733. . View in PubMed
  • Status Epilepticus and Beyond: A Clinical Review of Status Epilepticus and an Update on Current Management Strategies in Super-refractory Status Epilepticus Korean J Crit Care Med. 2017 May; 32(2):89-105. . View in PubMed
  • AEDs after ICH: Preventing the prophylaxis Neurology. 2017 01 03; 88(1):15-16. . View in PubMed
  • Incontinence and gait disturbance after intraventricular extension of intracerebral hemorrhage Neurology. 2016 Mar 08; 86(10):905-11. . View in PubMed
  • Therapeutic Hypothermia After Resuscitation From a Non-Shockable Rhythm Improves Outcomes in a Regionalized System of Cardiac Arrest Care Neurocrit Care. 2016 Feb; 24(1):90-6. . View in PubMed
  • Emergency Neurological Life Support: Acute Ischemic Stroke Neurocrit Care. 2015 Dec; 23 Suppl 2:S94-102. . View in PubMed
  • Prophylactic Antiepileptic Drug Use and Outcome in the Ethnic/Racial Variations of Intracerebral Hemorrhage Study Stroke. 2015 Dec; 46(12):3532-5. . View in PubMed
  • A Consensus-Based Interpretation of the Benchmark Evidence from South American Trials: Treatment of Intracranial Pressure Trial J Neurotrauma. 2015 Nov 15; 32(22):1722-4. . View in PubMed
  • Emergent operation for isolated severe traumatic brain injury: Does time matter? J Trauma Acute Care Surg. 2015 Nov; 79(5):838-42.. View in PubMed
  • Alternative clinical trial design in neurocritical care Neurocrit Care. 2015 Jun; 22(3):378-84. . View in PubMed
  • Prehospital use of magnesium sulfate as neuroprotection in acute stroke N Engl J Med. 2015 Feb 05; 372(6):528-36. . View in PubMed
  • Treatment and outcomes of ST segment elevation myocardial infarction and out-of-hospital cardiac arrest in a regionalized system of care based on presence or absence of initial shockable cardiac arrest rhythm Am J Cardiol. 2014 Oct 01; 114(7):968-71. . View in PubMed
  • Survival and neurologic outcome after out-of-hospital cardiac arrest: results one year after regionalization of post-cardiac arrest care in a large metropolitan area Prehosp Emerg Care. 2014 Apr-Jun; 18(2):217-23. . View in PubMed
  • Methodology of the Field Administration of Stroke Therapy – Magnesium (FAST-MAG) phase 3 trial: Part 1 – rationale and general methods Int J Stroke. 2014 Feb; 9(2):215-9. . View in PubMed
  • Methodology of the Field Administration of Stroke Therapy – Magnesium (FAST-MAG) phase 3 trial: Part 2 – prehospital study methods Int J Stroke. 2014 Feb; 9(2):220-5. . View in PubMed
  • The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study protocol Stroke. 2013 Oct; 44(10):e120-5. . View in PubMed
  • Emergency neurological life support: acute ischemic stroke Neurocrit Care. 2012 Sep; 17 Suppl 1:S29-36. . View in PubMed
  • Impact of systems of care and blood pressure management on stroke outcomes Popul Health Manag. 2011 Dec; 14(6):267-75. . View in PubMed
  • Effect of time to reperfusion on clinical outcome of anterior circulation strokes treated with thrombectomy: pooled analysis of the MERCI and Multi MERCI trials Stroke. 2011 Nov; 42(11):3144-9. . View in PubMed
  • Clinical practices, complications, and mortality in neurological patients with acute severe hypertension: the Studying the Treatment of Acute hyperTension registry Crit Care Med. 2011 Oct; 39(10):2330-6. . View in PubMed
  • Local brain temperature reduction through intranasal cooling with the RhinoChill device: preliminary safety data in brain-injured patients Stroke. 2011 Aug; 42(8):2164-9. . View in PubMed
  • Therapeutic hypothermia in acute ischemic stroke Neurosurg Focus. 2011 Jun; 30(6):E17. . View in PubMed
  • Metrics for measuring quality of care in comprehensive stroke centers: detailed follow-up to Brain Attack Coalition comprehensive stroke center recommendations: a statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke. 2011 Mar; 42(3):849-77. . View in PubMed
  • The case for simplifying brain death criteria Neurology. 2011 Jan 11; 76(2):113-4. . View in PubMed
  • Predictors of 90-day readmission among patients with acute severe hypertensionThe cross-sectional observational Studying the Treatment of Acute hyperTension (STAT) study. Am Heart J. 2010 Sep; 160(3):521-527. e1. . View in PubMed
  • Predictors of good clinical outcomes, mortality, and successful revascularization in patients with acute ischemic stroke undergoing thrombectomy: pooled analysis of the Mechanical Embolus Removal in Cerebral Ischemia (MERCI) and Multi MERCI Trials Stroke. 2009 Dec; 40(12):3777-83. . View in PubMed
  • Practice patterns, outcomes, and end-organ dysfunction for patients with acute severe hypertension: the Studying the Treatment of Acute hyperTension (STAT) registryAm Heart J. 2009 Oct; 158(4):599-606. e1. . View in PubMed
  • A review of selective hypothermia in the management of traumatic brain injury Neurosurg Focus. 2008 Oct; 25(4):E9. . View in PubMed
  • Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial Stroke. 2008 Apr; 39(4):1205-12. . View in PubMed
  • Core curriculum and competencies for advanced training in neurological intensive care: United Council for Neurologic Subspecialties guidelines Neurocrit Care. 2006; 5(2):159-65. . View in PubMed
  • Program requirements for fellowship training in neurological intensive care: United Council for Neurologic Subspecialties guidelines Neurocrit Care. 2006; 5(2):166-71. . View in PubMed
  • Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial Stroke. 2005 Jul; 36(7):1432-8. . View in PubMed
  • A 70-year-old woman with poor grade subarachnoid hemorrhage complicated by carotid stenosis, cerebral vasospasm, and cerebral rebleed Neurocrit Care. 2005; 3(2):183-8. . View in PubMed
  • The acute cerebrovascular event: surgical and other interventional therapies Emerg Med Clin North Am. 2003 Nov; 21(4):847-72. . View in PubMed
  • Central retinal artery occlusion associated with intranasal methamphetamine use J Stroke Cerebrovasc Dis. 2003 Jul-Aug; 12(4):207-8. . View in PubMed
  • Acute Treatment of Cerebral Venous Thrombosis Curr Treat Options Neurol. 2002 Jul; 4(4):319-322. . View in PubMed
  • Prognostic significance of hypernatremia and hyponatremia among patients with aneurysmal subarachnoid hemorrhage Neurosurgery. 2002 Apr; 50(4):749-55; discussion 755-6. . View in PubMed
  • Early false-negative diffusion-weighted imaging in brainstem infarction J Stroke Cerebrovasc Dis. 2002 Jan-Feb; 11(1):51-3. . View in PubMed
  • Outcomes of neurocritical care Curr Neurol Neurosci Rep. 2001 Nov; 1(6):593-8. . View in PubMed
  • Vertebrobasilar dolichoectasia associated with Marfan syndrome J Stroke Cerebrovasc Dis. 2000 Jul-Aug; 9(4):196-8. . View in PubMed
  • Early identification of patients at risk for symptomatic vasospasm after aneurysmal subarachnoid hemorrhage Crit Care Med. 2000 Apr; 28(4):984-90. . View in PubMed
  • Factors associated with aneurysm size in patients with subarachnoid hemorrhage: effect of smoking and aneurysm location Neurosurgery. 2000 Jan; 46(1):44-50. . View in PubMed
  • Prognostic value and determinants of ultraearly angiographic vasospasm after aneurysmal subarachnoid hemorrhage Neurosurgery. 1999 May; 44(5):967-73; discussion 973-4. . View in PubMed
  • Complex partial status epilepticus accompanied by serious morbidity and mortality Neurology. 1995 Aug; 45(8):1499-504. . View in PubMed

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