Faculty

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Hisham Abdel-Azim, MD
Associate Professor of Pediatrics (Clinical Scholar)
Pediatrics
CHL Mail Stop 62 Off Campus Los Angeles
+1 323 361 5664

Publications

Donor Experiences of Second Marrow or Peripheral Blood Stem Cell Collection Mirror the First, but CD34+ Yields are Less. Biol Blood Marrow Transplant. 2017 Sep 25. View in: PubMed

The PI3Kd Inhibitor Idelalisib Inhibits Homing in an in Vitro and in Vivo Model of B ALL. Cancers (Basel). 2017 Sep 10; 9(9). View in: PubMed

Outcomes following autologous hematopoietic stem cell transplant for patients with relapsed Wilms' tumor: a CIBMTR retrospective analysis. Bone Marrow Transplant. 2017 Sep 04. View in: PubMed

Humoral Immune Reconstitution Kinetics after Allogeneic Hematopoietic Stem Cell Transplantation in Children: A Maturation Block of IgM Memory B Cells May Lead to Impaired Antibody Immune Reconstitution. Biol Blood Marrow Transplant. 2017 Sep; 23(9):1437-1446. View in: PubMed

Personalized Prognostic Risk Score for Long-Term Survival for Children with Acute Leukemia after Allogeneic Transplantation. Biol Blood Marrow Transplant. 2017 Sep; 23(9):1523-1530. View in: PubMed

Clinical risks and healthcare utilization of haematopoietic cell transplantation for sickle cell disease in the U. S. using merged databases. Haematologica. 2017 Aug 17. View in: PubMed

Hematopoietic Stem Cell Transplantation Activity in Pediatric Cancer between 2008 and 2014 in the United States: A Center for International Blood and Marrow Transplant Research Report. Biol Blood Marrow Transplant. 2017 Aug; 23(8):1342-1349. View in: PubMed

Phase I Study of Clofarabine and 2-Gy Total Body Irradiation as a Nonmyeloablative Preparative Regimen for Hematopoietic Stem Cell Transplantation in Pediatric Patients with Hematologic Malignancies: A Therapeutic Advances in Childhood Leukemia Consortium Study. Biol Blood Marrow Transplant. 2017 Jul; 23(7):1134-1141. View in: PubMed

Role of aß T Cell Depletion in Prevention of Graft versus Host Disease. Biomedicines. 2017 Jun 26; 5(3). View in: PubMed

Outcomes after Umbilical Cord Blood Transplantation for Myelodysplastic Syndromes. Biol Blood Marrow Transplant. 2017 Jun; 23(6):971-979. View in: PubMed

Phase I Study of Clofarabine and 2-Gy Total Body Irradiation as a Non-Myeloablative Preparative Regimen for Hematopoietic Stem Cell Transplantation (HSCT) in Pediatric Patients with Hematologic Malignancies: a Therapeutic Advances in Childhood Leukemia (TACL) Consortium Study. Biol Blood Marrow Transplant. 2017 Apr 07. View in: PubMed

Outcomes after Umbilical Cord Blood Transplantation for Myelodysplastic Syndromes. Biol Blood Marrow Transplant. 2017 Mar 10. View in: PubMed

GvHD after umbilical cord blood transplantation for acute leukemia: an analysis of risk factors and effect on outcomes. Bone Marrow Transplant. 2017 Mar; 52(3):400-408. View in: PubMed

Am80-GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia-associated infection and mortality. EMBO Mol Med. 2016 Oct 13. View in: PubMed

Human leukocyte antigen supertype matching after myeloablative hematopoietic cell transplantation with 7/8 matched unrelated donor allografts: a report from the Center for International Blood and Marrow Transplant Research. Haematologica. 2016 Oct; 101(10):1267-1274. View in: PubMed

Infection Rates among Acute Leukemia Patients Receiving Alternative Donor Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2016 Sep; 22(9):1636-45. View in: PubMed

Infection Rates among Acute Leukemia Patients Receiving Alternative Donor Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2016 Sep; 22(9):1636-1645. View in: PubMed

Outcomes of Allogeneic Hematopoietic Cell Transplantation in Children and Young Adults with Chronic Myeloid Leukemia: A CIBMTR Cohort Analysis. Biol Blood Marrow Transplant. 2016 Jun; 22(6):1056-64. View in: PubMed

Reply: T-Cell Acute Lymphoblastic Leukemia, Minimal Residual Disease, and Lymphocyte Recovery. Pediatr Blood Cancer. 2016 May; 63(5):945. View in: PubMed

The incidence, mortality and timing of Pneumocystis jiroveci pneumonia after hematopoietic cell transplantation: a CIBMTR analysis. Bone Marrow Transplant. 2016 Apr; 51(4):573-80. View in: PubMed

Transcriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacetylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B-cell Acute Lymphoblastic Leukemia. J Biol Chem. 2016 Feb 19; 291(8):4004-18. View in: PubMed

Am80-GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia-associated infection and mortality. EMBO Mol Med. 2016 11; 8(11):1340-1359. View in: PubMed

A prognostic model predicting autologous transplantation outcomes in children, adolescents and young adults with Hodgkin lymphoma. Bone Marrow Transplant. 2015 Nov; 50(11):1416-23. View in: PubMed

Unrelated donor hematopoietic stem cell transplantation for the treatment of non-malignant genetic diseases: An alemtuzumab based regimen is associated with cure of clinical disease; earlier clearance of alemtuzumab may be associated with graft rejection. Am J Hematol. 2015 Nov; 90(11):1021-6. View in: PubMed

End of induction minimal residual disease alone is not a useful determinant for risk stratified therapy in pediatric T-cell acute lymphoblastic leukemia. Pediatr Blood Cancer. 2015 Nov; 62(11):2040-3. View in: PubMed

Analysis of the Effect of Race, Socioeconomic Status, and Center Size on Unrelated National Marrow Donor Program Donor Outcomes: Donor Toxicities Are More Common at Low-Volume Bone Marrow Collection Centers. Biol Blood Marrow Transplant. 2015 Oct; 21(10):1830-8. View in: PubMed

Second Allogeneic Hematopoietic Cell Transplantation for Patients with Fanconi Anemia and Bone Marrow Failure. Biol Blood Marrow Transplant. 2015 Oct; 21(10):1790-5. View in: PubMed

Graft versus tumor effect in the brain of a child with recurrent metastatic medulloblastoma. Pediatr Blood Cancer. 2015 Sep; 62(9):1667-9. View in: PubMed

Improved outcomes associated with hematopoietic stem cell transplantation for patients with juvenile myelomonocytic leukemia. Blood. 2015 Jul 23; 126(4):561-2. View in: PubMed

Transplantation Outcomes for Children with Hypodiploid Acute Lymphoblastic Leukemia. Biol Blood Marrow Transplant. 2015 Jul; 21(7):1273-7. View in: PubMed

Low-dose total-body irradiation and alemtuzumab-based reduced-intensity conditioning regimen results in durable engraftment and correction of clinical disease among children with chronic granulomatous disease. Pediatr Transplant. 2015 Jun; 19(4):408-12. View in: PubMed

B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3. Oncotarget. 2015 May 10; 6(13):11378-94. View in: PubMed

Successful bone marrow transplantation of an adolescent young adult female with pregnancy-associated aplastic anemia. J Pediatr Hematol Oncol. 2015 May; 37(4):319-21. View in: PubMed

Cytotoxicity of CD56-positive lymphocytes against autologous B-cell precursor acute lymphoblastic leukemia cells. Leukemia. 2015 Apr; 29(4):788-97. View in: PubMed

A survey of infectious disease clinical practices among pediatric blood and marrow transplant programs in the United States. Pediatr Blood Cancer. 2015 Apr; 62(4):731-5. View in: PubMed

A reduced-toxicity regimen is associated with durable engraftment and clinical cure of nonmalignant genetic diseases among children undergoing blood and marrow transplantation with an HLA-matched related donor. Biol Blood Marrow Transplant. 2015 Mar; 21(3):440-4. View in: PubMed

Potential of autologous NK cell therapy to eradicate leukemia: "Education is [not] the best provision for old age" -Aristotle. Oncoimmunology. 2015 Feb; 4(2):e984549. View in: PubMed

Phosphoflow-Based Evaluation of Mek Inhibitors as Small-Molecule Therapeutics for B-Cell Precursor Acute Lymphoblastic Leukemia. PLoS One. 2015; 10(9):e0137917. View in: PubMed

Obesity is associated with residual leukemia following induction therapy for childhood B-precursor acute lymphoblastic leukemia. Blood. 2014 Dec 18; 124(26):3932-8. View in: PubMed

Bortezomib for effective treatment of a child with refractory autoimmune hemolytic anemia post allogeneic hematopoietic stem cell transplant. Pediatr Blood Cancer. 2014 Dec; 61(12):2324-5. View in: PubMed

Overcoming psychosocial and developmental barriers to blood and marrow transplantation (BMT) in an adolescent/young adult (AYA) transgender patient with chronic myelogenous leukemia. Pediatr Hematol Oncol. 2014 Nov; 31(8):765-7. View in: PubMed

Immunologic resolution of human chronic graft-versus-host disease. Biol Blood Marrow Transplant. 2014 Oct; 20(10):1508-15. View in: PubMed

Effector-mediated eradication of precursor B acute lymphoblastic leukemia with a novel Fc-engineered monoclonal antibody targeting the BAFF-R. Mol Cancer Ther. 2014 Jun; 13(6):1567-77. View in: PubMed

Human Lymphoid Development in the Absence of Common ?-Chain Receptor Signaling. J Immunol. 2014 Jun 1; 192(11):5050-8. View in: PubMed

Human lymphoid development in the absence of common ?-chain receptor signaling. J Immunol. 2014 Jun 01; 192(11):5050-8. View in: PubMed

Transplantation for children with acute myeloid leukemia: a comparison of outcomes with reduced intensity and myeloablative regimens. Blood. 2014 Mar 6; 123(10):1615-20. View in: PubMed

Transplantation for children with acute myeloid leukemia: a comparison of outcomes with reduced intensity and myeloablative regimens. Blood. 2014 Mar 06; 123(10):1615-20. View in: PubMed

Galectin-3 in pre-B acute lymphoblastic leukemia. Leukemia. 2013 Dec; 27(12):2385-8. View in: PubMed

ß-globin gene transfer to human bone marrow for sickle cell disease. J Clin Invest. 2013 Jul 1. View in: PubMed

ß-globin gene transfer to human bone marrow for sickle cell disease. J Clin Invest. 2013 Jul 01. View in: PubMed

Circulating hematopoietic and endothelial progenitor cells in newborn infants: effects of gestational age, postnatal age and clinical stress in the first 3 weeks of life. Early Hum Dev. 2013 Jun; 89(6):411-8. View in: PubMed

O-acetylated N-acetylneuraminic acid as a novel target for therapy in human pre-B acute lymphoblastic leukemia. J Exp Med. 2013 Apr 8; 210(4):805-19. View in: PubMed

O-acetylated N-acetylneuraminic acid as a novel target for therapy in human pre-B acute lymphoblastic leukemia. J Exp Med. 2013 Apr 08; 210(4):805-19. View in: PubMed

Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans. Blood. 2012 Nov 01; 120(18):3635-46. View in: PubMed

Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans. Blood. 2012 Nov 1; 120(18):3635-46. View in: PubMed

Clinical and genetic heterogeneity in Omenn syndrome and severe combined immune deficiency. Pediatr Transplant. 2009 Mar; 13(2):244-50. View in: PubMed

Pre- and post-natal treatment of hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2009 Jan; 52(1):139-42. View in: PubMed

Expansion of multipotent and lymphoid-committed human progenitors through intracellular dimerization of Mpl. Blood. 2008 Apr 15; 111(8):4064-74. View in: PubMed

Congenital bilateral upper eyelid coloboma. J Perinatol. 2003 Mar; 23(2):166-7. View in: PubMed

Risk factors in intermediate and high-grade non-Hodgkin's lymphomas of adults: a need for a new staging system. Anticancer Drugs. 1991 Aug; 2(4):383-8. View in: PubMed

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