Faculty

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Malcolm C Pike, PhD
Professor of Preventive Medicine
Preventive Medicine
200 Cabrini Boulevard Health Sciences Campus New York
+1 323 865 0405

Overview

Dr. Pike's main research interest is the chemoprevention of female cancers by a hormonal contraceptive approach. He also has a major interest in the effects of pregnancy on long-term prevention of breast, endometrial, and ovarian cancer.

Publications

Timing of births and oral contraceptive use influences ovarian cancer risk. Int J Cancer. 2017 Jul 27. View in: PubMed

Radiation-associated breast cancer and gonadal hormone exposure: a report from the Childhood Cancer Survivor Study. Br J Cancer. 2017 Jul 11; 117(2):290-299. View in: PubMed

Breastfeeding and Endometrial Cancer Risk: An Analysis From the Epidemiology of Endometrial Cancer Consortium. Obstet Gynecol. 2017 Jun; 129(6):1059-1067. View in: PubMed

Cigarette smoking is associated with adverse survival among women with ovarian cancer: Results from a pooled analysis of 19 studies. Int J Cancer. 2017 Jun 01; 140(11):2422-2435. View in: PubMed

Endogenous thrombin potential changes during the first cycle of oral contraceptive use. Contraception. 2017 May; 95(5):456-463. View in: PubMed

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. Nat Genet. 2017 May; 49(5):680-691. View in: PubMed

Use of common analgesic medications and ovarian cancer survival: results from a pooled analysis in the Ovarian Cancer Association Consortium. Br J Cancer. 2017 Apr 25; 116(9):1223-1228. View in: PubMed

Estimating systemic exposure to levonorgestrel from an oral contraceptive. Contraception. 2017 Apr; 95(4):398-404. View in: PubMed

Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci. Br J Cancer. 2017 Feb 14; 116(4):524-535. View in: PubMed

Dietary Factors Reduce Risk of Acute Pancreatitis in a Large Multiethnic Cohort. Clin Gastroenterol Hepatol. 2017 Feb; 15(2):257-265. e3. View in: PubMed

A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer. Int J Cancer. 2016 Dec 15; 139(12):2646-2654. View in: PubMed

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS. J Med Genet. 2016 Dec; 53(12):800-811. View in: PubMed

Uterine Cancer After Risk-Reducing Salpingo-oophorectomy Without Hysterectomy in Women With BRCA Mutations. JAMA Oncol. 2016 Nov 01; 2(11):1434-1440. View in: PubMed

Risk Prediction for Epithelial Ovarian Cancer in 11 United States-Based Case-Control Studies: Incorporation of Epidemiologic Risk Factors and 17 Confirmed Genetic Loci. Am J Epidemiol. 2016 Oct 15; 184(8):579-589. View in: PubMed

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types. Cancer Discov. 2016 Sep; 6(9):1052-67. View in: PubMed

Chronic Recreational Physical Inactivity and Epithelial Ovarian Cancer Risk: Evidence from the Ovarian Cancer Association Consortium. Cancer Epidemiol Biomarkers Prev. 2016 Jul; 25(7):1114-24. View in: PubMed

Recreational physical inactivity and mortality in women with invasive epithelial ovarian cancer: evidence from the Ovarian Cancer Association Consortium. Br J Cancer. 2016 Jun 28; 115(1):95-101. View in: PubMed

Risk-Reducing Surgery in Hereditary Breast and Ovarian Cancer. N Engl J Med. 2016 Jun 16; 374(24):2403-4. View in: PubMed

Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study. Int J Epidemiol. 2016 Jun; 45(3):884-95. View in: PubMed

Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk. Obstet Gynecol. 2016 May; 127(5):828-36. View in: PubMed

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer. Gynecol Oncol. 2016 May; 141(2):386-401. View in: PubMed

The association between socioeconomic status and tumour stage at diagnosis of ovarian cancer: A pooled analysis of 18 case-control studies. Cancer Epidemiol. 2016 Apr; 41:71-9. View in: PubMed

Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12. 2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry. Hum Mol Genet. 2016 Mar 15; 25(6):1203-14. View in: PubMed

Investigation of Exomic Variants Associated with Overall Survival in Ovarian Cancer. Cancer Epidemiol Biomarkers Prev. 2016 Mar; 25(3):446-54. View in: PubMed

A targeted genetic association study of epithelial ovarian cancer susceptibility. Oncotarget. 2016 Feb 16; 7(7):7381-9. View in: PubMed

Prospective Study of Alcohol Drinking, Smoking, and Pancreatitis: The Multiethnic Cohort. Pancreas. 2016 07; 45(6):819-25. View in: PubMed

Assessment of Multifactor Gene-Environment Interactions and Ovarian Cancer Risk: Candidate Genes, Obesity, and Hormone-Related Risk Factors. Cancer Epidemiol Biomarkers Prev. 2016 05; 25(5):780-90. View in: PubMed

Clotting factor changes during the first cycle of oral contraceptive use. Contraception. 2016 Jan; 93(1):70-6. View in: PubMed

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer. Oncotarget. 2016 10 25; 7(43):69097-69110. View in: PubMed

Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types. J Natl Cancer Inst. 2015 Dec; 107(12):djv279. View in: PubMed

Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk. Genet Epidemiol. 2015 Dec; 39(8):689-97. View in: PubMed

Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium. Clin Cancer Res. 2015 Dec 01; 21(23):5264-76. View in: PubMed

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer. Carcinogenesis. 2015 Nov; 36(11):1341-53. View in: PubMed

Gastric-type Endocervical Adenocarcinoma: An Aggressive Tumor With Unusual Metastatic Patterns and Poor Prognosis. Am J Surg Pathol. 2015 Nov; 39(11):1449-57. View in: PubMed

Brian E. Henderson: In Memoriam (1937-2015). Cancer Epidemiol Biomarkers Prev. 2015 Oct; 24(10):1437-8. View in: PubMed

Double-Blind Randomized 12-Month Soy Intervention Had No Effects on Breast MRI Fibroglandular Tissue Density or Mammographic Density. Cancer Prev Res (Phila). 2015 Oct; 8(10):942-51. View in: PubMed

Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk. Cancer Epidemiol Biomarkers Prev. 2015 Oct; 24(10):1574-84. View in: PubMed

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer. Nat Commun. 2015 Sep 22; 6:8234. View in: PubMed

African Americans and Hispanics Remain at Lower Risk of Ovarian Cancer Than Non-Hispanic Whites after Considering Nongenetic Risk Factors and Oophorectomy Rates. Cancer Epidemiol Biomarkers Prev. 2015 Jul; 24(7):1094-100. View in: PubMed

Enhanced GAB2 Expression Is Associated with Improved Survival in High-Grade Serous Ovarian Cancer and Sensitivity to PI3K Inhibition. Mol Cancer Ther. 2015 Jun; 14(6):1495-503. View in: PubMed

Estimating systemic exposure to ethinyl estradiol from an oral contraceptive. Am J Obstet Gynecol. 2015 May; 212(5):614. e1-7. View in: PubMed

Population distribution of lifetime risk of ovarian cancer in the United States. Cancer Epidemiol Biomarkers Prev. 2015 Apr; 24(4):671-676. View in: PubMed

Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study. Gynecol Oncol. 2015 Mar; 136(3):542-8. View in: PubMed

The role of systemic chemotherapy in the management of granulosa cell tumors. Gynecol Oncol. 2015 Mar; 136(3):505-11. View in: PubMed

Identification of six new susceptibility loci for invasive epithelial ovarian cancer. Nat Genet. 2015 Feb; 47(2):164-71. View in: PubMed

Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC). J Genet Genome Res. 2015; 2(2). View in: PubMed

Treatment of Endometriosis with the GnRHa Deslorelin and Add-Back Estradiol and Supplementary Testosterone. Biomed Res Int. 2015; 2015:934164. View in: PubMed

Brca1 Mutations Enhance Mouse Reproductive Functions by Increasing Responsiveness to Male-Derived Scent. PLoS One. 2015; 10(10):e0139013. View in: PubMed

Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk. PLoS One. 2015; 10(6):e0128106. View in: PubMed

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15. 33. Hum Mol Genet. 2014 Dec 15; 23(24):6616-33. View in: PubMed

The 19q12 bladder cancer GWAS signal: association with cyclin E function and aggressive disease. Cancer Res. 2014 Oct 15; 74(20):5808-18. View in: PubMed

Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk. Mol Nutr Food Res. 2014 Oct; 58(10):2023-35. View in: PubMed

Genome-wide interaction study of smoking and bladder cancer risk. Carcinogenesis. 2014 Aug; 35(8):1737-44. View in: PubMed

Comprehensive analyses of DNA repair pathways, smoking and bladder cancer risk in Los Angeles and Shanghai. Int J Cancer. 2014 Jul 15; 135(2):335-47. View in: PubMed

Variation in NF-?B signaling pathways and survival in invasive epithelial ovarian cancer. Cancer Epidemiol Biomarkers Prev. 2014 Jul; 23(7):1421-7. View in: PubMed

Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA. Hum Genet. 2014 May; 133(5):481-97. View in: PubMed

Large-scale evaluation of common variation in regulatory T cell-related genes and ovarian cancer outcome. Cancer Immunol Res. 2014 Apr; 2(4):332-40. View in: PubMed

Anthropometric and hormonal risk factors for male breast cancer: male breast cancer pooling project results. J Natl Cancer Inst. 2014 Mar; 106(3):djt465. View in: PubMed

Genome-wide association study identifies multiple loci associated with bladder cancer risk. Hum Mol Genet. 2014 Mar 01; 23(5):1387-98. View in: PubMed

Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium. J Natl Cancer Inst. 2014 Feb; 106(2):djt431. View in: PubMed

Risk of ovarian cancer and the NF-?B pathway: genetic association with IL1A and TNFSF10. Cancer Res. 2014 Feb 01; 74(3):852-61. View in: PubMed

Dietary sources of N-nitroso compounds and bladder cancer risk: findings from the Los Angeles bladder cancer study. Int J Cancer. 2014 Jan 01; 134(1):125-35. View in: PubMed

Effect of finasteride on serum levels of androstenedione, testosterone and their 5a-reduced metabolites in men at risk for prostate cancer. J Steroid Biochem Mol Biol. 2013 Nov; 138:10-6. View in: PubMed

Comparison of 3-point Dixon imaging and fuzzy C-means clustering methods for breast density measurement. J Magn Reson Imaging. 2013 Aug; 38(2):474-81. View in: PubMed

Genital powder use and risk of ovarian cancer: a pooled analysis of 8,525 cases and 9,859 controls. Cancer Prev Res (Phila). 2013 Aug; 6(8):811-21. View in: PubMed

Type I and II endometrial cancers: have they different risk factors? J Clin Oncol. Type I and II endometrial cancers: have they different risk factors? J Clin Oncol. 2013 Jul 10; 31(20):2607-18. View in: PubMed

Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics. Cell Stem Cell. 2013 Jul 03; 13(1):117-30. View in: PubMed

Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23. Hum Mol Genet. 2013 Jul 01; 22(13):2748-53. View in: PubMed

Analysis of over 10,000 Cases finds no association between previously reported candidate polymorphisms and ovarian cancer outcome. Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):987-92. View in: PubMed

Cigarette smoking and risk of ovarian cancer: a pooled analysis of 21 case-control studies. Cancer Causes Control. 2013 May; 24(5):989-1004. View in: PubMed

Elevated 4-aminobiphenyl and 2,6-dimethylaniline hemoglobin adducts and increased risk of bladder cancer among lifelong nonsmokers--The Shanghai Bladder Cancer Study. Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):937-45. View in: PubMed

Combined and interactive effects of environmental and GWAS-identified risk factors in ovarian cancer. Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):880-90. View in: PubMed

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nat Genet. 2013 Apr; 45(4):362-70, 370e1-2. View in: PubMed

Obesity and risk of ovarian cancer subtypes: evidence from the Ovarian Cancer Association Consortium. Endocr Relat Cancer. 2013 Apr; 20(2):251-62. View in: PubMed

Tubal ligation and risk of ovarian cancer subtypes: a pooled analysis of case-control studies. Int J Epidemiol. 2013 Apr; 42(2):579-89. View in: PubMed

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet. 2013 Apr; 45(4):371-84, 384e1-2. View in: PubMed

Risk of asynchronous contralateral breast cancer in noncarriers of BRCA1 and BRCA2 mutations with a family history of breast cancer: a report from the Women's Environmental Cancer and Radiation Epidemiology Study. J Clin Oncol. 2013 Feb 01; 31(4):433-9. View in: PubMed

The effect of grapefruit intake on endogenous serum estrogen levels in postmenopausal women. Nutr Cancer. 2013; 65(5):644-52. View in: PubMed

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer. Nat Commun. 2013; 4:1628. View in: PubMed

Magnetic resonance imaging (MRI) of hormone-induced breast changes in young premenopausal women. Magn Reson Imaging. 2013 Jan; 31(1):1-9. View in: PubMed

Biological effects of green tea capsule supplementation in pre-surgery postmenopausal breast cancer patients. Front Oncol. 2013; 3:298. View in: PubMed

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21. 31. Nat Commun. 2013; 4:1627. View in: PubMed

Impact of menopausal status on background parenchymal enhancement and fibroglandular tissue on breast MRI. Eur Radiol. 2012 Dec; 22(12):2641-7. View in: PubMed

Impact of tamoxifen on amount of fibroglandular tissue, background parenchymal enhancement, and cysts on breast magnetic resonance imaging. Breast J. 2012 Nov-Dec; 18(6):527-34. View in: PubMed

Effect of aromatase inhibitors on background parenchymal enhancement and amount of fibroglandular tissue at breast MR imaging. Radiology. 2012 Sep; 264(3):670-8. View in: PubMed

Lowering oral contraceptive norethindrone dose increases estrogen and progesterone receptor levels with no reduction in proliferation of breast epithelium: a randomized trial. Contraception. 2012 Sep; 86(3):238-43. View in: PubMed

Age at last birth in relation to risk of endometrial cancer: pooled analysis in the epidemiology of endometrial cancer consortium. Am J Epidemiol. 2012 Aug 15; 176(4):269-78. View in: PubMed

Soy isoflavones for breast cancer risk reduction. Cancer Prev Res (Phila). 2012 Jul; 5(7):984-5; author reply 986-7. View in: PubMed

Alterations in Brca1 expression in mouse ovarian granulosa cells have short-term and long-term consequences on estrogen-responsive organs. Lab Invest. 2012 Jun; 92(6):802-11. View in: PubMed

Comment on "the predictive capacity of personal genome sequencing". Sci Transl Med. 2012 May 23; 4(135):135le3; author reply 135lr3. View in: PubMed

Predictors of noncompliance in an oral contraceptive clinical trial. Contraception. 2012 May; 85(5):465-9. View in: PubMed

Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies. Lancet Oncol. 2012 Apr; 13(4):385-94. View in: PubMed

Breast epithelial cell proliferation is markedly increased with short-term high levels of endogenous estrogen secondary to controlled ovarian hyperstimulation. Breast Cancer Res Treat. 2012 Apr; 132(2):653-60. View in: PubMed

Effect of 2-month controlled green tea intervention on lipoprotein cholesterol, glucose, and hormone levels in healthy postmenopausal women. Cancer Prev Res (Phila). 2012 Mar; 5(3):393-402. View in: PubMed

Shorter androgen receptor CAG repeat lengths associated with cryptorchidism risk among Hispanic white boys. J Clin Endocrinol Metab. 2012 Mar; 97(3):E393-9. View in: PubMed

Cigarette smoking and subtypes of bladder cancer. Int J Cancer. 2012 Feb 15; 130(4):896-901. View in: PubMed

Invasive breast cancer incidence trends by detailed race/ethnicity and age. Int J Cancer. 2012 Jan 15; 130(2):395-404. View in: PubMed

Re: Long-term outcomes of invasive ipsilateral breast tumor recurrences after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS. J Natl Cancer Inst. 2011 Nov 16; 103(22):1723. View in: PubMed

Heterogenous effect of androgen receptor CAG tract length on testicular germ cell tumor risk: shorter repeats associated with seminoma but not other histologic types. Carcinogenesis. 2011 Aug; 32(8):1238-43. View in: PubMed

Lower risk in parous women suggests that hormonal factors are important in bladder cancer etiology. Cancer Epidemiol Biomarkers Prev. 2011 Jun; 20(6):1156-70. View in: PubMed

The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing. Clin Cancer Res. 2011 Jun 01; 17(11):3742-50. View in: PubMed

Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer risk. Hum Mol Genet. 2011 Jun 01; 20(11):2263-72. View in: PubMed

Prostate cancer susceptibility polymorphism rs2660753 is not associated with invasive ovarian cancer. Cancer Epidemiol Biomarkers Prev. 2011 May; 20(5):1028-31. View in: PubMed

Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer. Int J Cancer. 2011 May 01; 128(9):2063-74. View in: PubMed

Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control study. Carcinogenesis. 2011 Feb; 32(2):197-202. View in: PubMed

Anthropometric, dietary, and hormonal correlates of serum adiponectin in Asian American women. Nutr Cancer. 2011; 63(4):549-57. View in: PubMed

Progesterone receptor gene polymorphisms and risk of endometriosis: results from an international collaborative effort. Fertil Steril. 2011 Jan; 95(1):40-5. View in: PubMed

Estrogen receptor beta rs1271572 polymorphism and invasive ovarian carcinoma risk: pooled analysis within the Ovarian Cancer Association Consortium. PLoS One. 2011; 6(6):e20703. View in: PubMed

Risk of urinary bladder cancer is associated with 8q24 variant rs9642880[T] in multiple racial/ethnic groups: results from the Los Angeles-Shanghai case-control study. Cancer Epidemiol Biomarkers Prev. 2010 Dec; 19(12):3150-6. View in: PubMed

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat Genet. 2010 Nov; 42(11):978-84. View in: PubMed

Hypertension, diuretics and antihypertensives in relation to bladder cancer. Carcinogenesis. 2010 Nov; 31(11):1964-71. View in: PubMed

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. Nat Genet. 2010 Oct; 42(10):874-9. View in: PubMed

Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". PLoS Genet. 2010 Jul 08; 6(7):e1001016. View in: PubMed

Pharmacokinetics of a combined oral contraceptive in obese and normal-weight women. Contraception. 2010 Jun; 81(6):474-80. View in: PubMed

Patterns of regular use of mammography--body weight and ethnicity: the Multiethnic Cohort. J Am Acad Nurse Pract. 2010 Mar; 22(3):162-9. View in: PubMed

National Institutes of Health State-of-the-Science Conference statement: Diagnosis and Management of Ductal Carcinoma In Situ September 22-24, 2009. J Natl Cancer Inst. 2010 Feb 03; 102(3):161-9. View in: PubMed

Long-term postmenopausal hormone therapy and endometrial cancer. Cancer Epidemiol Biomarkers Prev. 2010 Feb; 19(2):475-83. View in: PubMed

Polymorphism in the GALNT1 gene and epithelial ovarian cancer in non-Hispanic white women: the Ovarian Cancer Association Consortium. Cancer Epidemiol Biomarkers Prev. 2010 Feb; 19(2):600-4. View in: PubMed

Low level alcohol intake, cigarette smoking and risk of breast cancer in Asian-American women. Breast Cancer Res Treat. 2010 Feb; 120(1):203-10. View in: PubMed

Changes in the mouse estrus cycle in response to BRCA1 inactivation suggest a potential link between risk factors for familial and sporadic ovarian cancer. Cancer Res. 2010 Jan 01; 70(1):221-8. View in: PubMed

ESR1/SYNE1 polymorphism and invasive epithelial ovarian cancer risk: an Ovarian Cancer Association Consortium study. Cancer Epidemiol Biomarkers Prev. 2010 Jan; 19(1):245-50. View in: PubMed

Familial correlations in postmenopausal serum concentrations of sex steroid hormones and other mitogens: a twins and sisters study. J Clin Endocrinol Metab. 2009 Dec; 94(12):4793-800. View in: PubMed

Sequence variant on 3q28 and urinary bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control study. Cancer Epidemiol Biomarkers Prev. 2009 Nov; 18(11):3057-61. View in: PubMed

Progesterone and estrogen receptors in pregnant and premenopausal non-pregnant normal human breast. Breast Cancer Res Treat. 2009 Nov; 118(1):161-8. View in: PubMed

Breast cancer risk and hysterectomy status: the Multiethnic Cohort study. Cancer Causes Control. 2009 Jul; 20(5):539-47. View in: PubMed

Polymorphisms in the FGF2 gene and risk of serous ovarian cancer: results from the ovarian cancer association consortium. Twin Res Hum Genet. 2009 Jun; 12(3):269-75. View in: PubMed

Breast cancer risk factors defined by estrogen and progesterone receptor status: the multiethnic cohort study. Am J Epidemiol. 2009 May 15; 169(10):1251-9. View in: PubMed

Ethnic differences in the use of regular mammography: the multiethnic cohort. Breast Cancer Res Treat. 2009 May; 115(1):163-70. View in: PubMed

Dietary patterns and breast cancer risk in Asian American women. Am J Clin Nutr. 2009 Apr; 89(4):1145-54. View in: PubMed

Childhood soy intake and breast cancer risk in Asian American women. Cancer Epidemiol Biomarkers Prev. 2009 Apr; 18(4):1050-9. View in: PubMed

Markers of inflammation and risk of ovarian cancer in Los Angeles County. Int J Cancer. 2009 Mar 15; 124(6):1409-15. View in: PubMed

Increased ovarian cancer risk associated with menopausal estrogen therapy is reduced by adding a progestin. Cancer. 2009 Feb 01; 115(3):531-9. View in: PubMed

Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. Cancer Epidemiol Biomarkers Prev. 2008 Dec; 17(12):3567-72. View in: PubMed

Association of vegetable, fruit, and grain intakes with colorectal cancer: the Multiethnic Cohort Study. Am J Clin Nutr. 2008 Sep; 88(3):730-7. View in: PubMed

No association between the SRD5A2 gene A49T missense variant and prostate cancer risk: lessons learned. Hum Mol Genet. 2008 Aug 15; 17(16):2456-61. View in: PubMed

Consortium analysis of 7 candidate SNPs for ovarian cancer. Int J Cancer. 2008 Jul 15; 123(2):380-388. View in: PubMed

IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3). PLoS One. 2008 Jul 02; 3(7):e2578. View in: PubMed

Predictors of the timing of natural menopause in the Multiethnic Cohort Study. Am J Epidemiol. 2008 Jun 01; 167(11):1287-94. View in: PubMed

Interleukin-2, interleukin-12, and interferon-gamma levels and risk of young adult Hodgkin lymphoma. Blood. 2008 Apr 01; 111(7):3377-82. View in: PubMed

Does breast size modify the association between mammographic density and breast cancer risk? Cancer Epidemiol Biomarkers Prev. Does breast size modify the association between mammographic density and breast cancer risk? Cancer Epidemiol Biomarkers Prev. 2008 Mar; 17(3):621-7. View in: PubMed

Alcohol consumption and endometrial cancer risk: the multiethnic cohort. Int J Cancer. 2008 Feb 01; 122(3):634-8. View in: PubMed

Comprehensive evaluation of ESR2 variation and ovarian cancer risk. Cancer Epidemiol Biomarkers Prev. 2008 Feb; 17(2):393-6. View in: PubMed

Haplotypes of the estrogen receptor beta gene and breast cancer risk. Int J Cancer. 2008 Jan 15; 122(2):387-92. View in: PubMed

A comprehensive analysis of common genetic variation in prolactin (PRL) and PRL receptor (PRLR) genes in relation to plasma prolactin levels and breast cancer risk: the multiethnic cohort. BMC Med Genet. 2007 Dec 01; 8:72. View in: PubMed

Nonsteroidal antiinflammatory drugs and breast cancer risk: the multiethnic cohort. Am J Epidemiol. 2007 Nov 15; 166(10):1150-8. View in: PubMed

CYP17 genetic variation and risk of breast and prostate cancer from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3). Cancer Epidemiol Biomarkers Prev. 2007 Nov; 16(11):2237-46. View in: PubMed

Sequence variants of estrogen receptor beta and risk of prostate cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium. Cancer Epidemiol Biomarkers Prev. 2007 Oct; 16(10):1973-81. View in: PubMed

Dietary fiber and colorectal cancer risk: the multiethnic cohort study. Cancer Causes Control. 2007 Sep; 18(7):753-64. View in: PubMed

Tamoxifen, soy, and lifestyle factors in Asian American women with breast cancer. J Clin Oncol. 2007 Jul 20; 25(21):3024-30. View in: PubMed

Diabetes and risk of breast cancer in Asian-American women. Carcinogenesis. 2007 Jul; 28(7):1561-6. View in: PubMed

Multiple regions within 8q24 independently affect risk for prostate cancer. Nat Genet. 2007 May; 39(5):638-44. View in: PubMed

Established risk factors account for most of the racial differences in cardiovascular disease mortality. PLoS One. 2007 Apr 18; 2(4):e377. View in: PubMed

Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer. Cancer Res. 2007 Apr 01; 67(7):3027-35. View in: PubMed

A common 8q24 variant in prostate and breast cancer from a large nested case-control study. Cancer Res. 2007 Apr 01; 67(7):2951-6. View in: PubMed

Genetic variation at the CYP19A1 locus predicts circulating estrogen levels but not breast cancer risk in postmenopausal women. Cancer Res. 2007 Mar 01; 67(5):1893-7. View in: PubMed

Body size, hormone therapy and risk of breast cancer in Asian-American women. Int J Cancer. 2007 Feb 15; 120(4):844-52. View in: PubMed

Racial/ethnic differences in endometrial cancer risk: the multiethnic cohort study. Am J Epidemiol. 2007 Feb 01; 165(3):262-70. View in: PubMed

Reduced mammographic density with use of a gonadotropin-releasing hormone agonist-based chemoprevention regimen in BRCA1 carriers. Clin Cancer Res. 2007 Jan 15; 13(2 Pt 1):654-8. View in: PubMed

Estrogens, progestins, and risk of breast cancer. Ernst Schering Found Symp Proc. 2007; (1):127-50. View in: PubMed

Dietary fiber intake and endogenous serum hormone levels in naturally postmenopausal Mexican American women: the Multiethnic Cohort Study. Nutr Cancer. 2007; 58(2):127-35. View in: PubMed

A systematic assessment of common genetic variation in CYP11A and risk of breast cancer. Cancer Res. 2006 Dec 15; 66(24):12019-25. View in: PubMed

Prostate cancer incidence and intake of fruits, vegetables and related micronutrients: the multiethnic cohort study* (United States). Cancer Causes Control. 2006 Nov; 17(9):1193-207. View in: PubMed

Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort. Cancer Epidemiol Biomarkers Prev. 2006 Oct; 15(10):1993-7. View in: PubMed

BRCA1 and BRCA2 mutation carriers, oral contraceptive use, and breast cancer before age 50. Cancer Epidemiol Biomarkers Prev. 2006 Oct; 15(10):1863-70. View in: PubMed

Mammographic density, hormone therapy, and risk of breast cancer. Cancer Epidemiol Biomarkers Prev. 2006 Sep; 15(9):1750; author reply 1750. View in: PubMed

Postmenopausal hormone therapy and breast cancer risk: the Multiethnic Cohort. Int J Cancer. 2006 Mar 01; 118(5):1285-91. View in: PubMed

Haplotype analysis of the HSD17B1 gene and risk of breast cancer: a comprehensive approach to multicenter analyses of prospective cohort studies. Cancer Res. 2006 Feb 15; 66(4):2468-75. View in: PubMed

Ethnic and racial differences in the smoking-related risk of lung cancer. N Engl J Med. 2006 Jan 26; 354(4):333-42. View in: PubMed

Common genetic variation in IGF1 and prostate cancer risk in the Multiethnic Cohort. J Natl Cancer Inst. 2006 Jan 18; 98(2):123-34. View in: PubMed

A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3). Breast Cancer Res. 2006; 8(5):R54. View in: PubMed

Dense breast stromal tissue shows greatly increased concentration of breast epithelium but no increase in its proliferative activity. Breast Cancer Res. 2006; 8(2):R24. View in: PubMed

Reproductive factors and breast cancer risk according to joint estrogen and progesterone receptor status: a meta-analysis of epidemiological studies. Breast Cancer Res. 2006; 8(4):R43. View in: PubMed

The Y deletion gr/gr and susceptibility to testicular germ cell tumor. Am J Hum Genet. 2005 Dec; 77(6):1034-43. View in: PubMed

Role of lipid peroxidation in the epidemiology and prevention of breast cancer. Cancer Epidemiol Biomarkers Prev. 2005 Dec; 14(12):2829-39. View in: PubMed

Genetic variation in the HSD17B1 gene and risk of prostate cancer. PLoS Genet. 2005 Nov; 1(5):e68. View in: PubMed

The association of endogenous sex steroids and sex steroid binding proteins with mammographic density: results from the Postmenopausal Estrogen/Progestin Interventions Mammographic Density Study. Am J Epidemiol. 2005 Nov 01; 162(9):826-34. View in: PubMed

Is mammographic density, as currently measured, a robust surrogate marker for breast cancer? Gynecol Endocrinol. Is mammographic density, as currently measured, a robust surrogate marker for breast cancer? Gynecol Endocrinol. 2005 Jul; 21 Suppl 1:17-21. View in: PubMed

The role of mammographic density in evaluating changes in breast cancer risk. Gynecol Endocrinol. 2005 Jul; 21 Suppl 1:1-5. View in: PubMed

Comparison of prostate-specific antigen and hormone levels among men in Singapore and the United States. Cancer Epidemiol Biomarkers Prev. 2005 Jul; 14(7):1692-6. View in: PubMed

A controlled 2-mo dietary fat reduction and soy food supplementation study in postmenopausal women. Am J Clin Nutr. 2005 May; 81(5):1133-41. View in: PubMed

Ethnic differences in neuroendocrine cell expression in normal human prostatic tissue. Urology. 2005 May; 65(5):1008-12. View in: PubMed

Cell-nonautonomous induction of ovarian and uterine serous cystadenomas in mice lacking a functional Brca1 in ovarian granulosa cells. Curr Biol. 2005 Mar 29; 15(6):561-5. View in: PubMed

Clarifying the PROGINS allele association in ovarian and breast cancer risk: a haplotype-based analysis. J Natl Cancer Inst. 2005 Jan 05; 97(1):51-9. View in: PubMed

Polymorphisms in genes involved in estrogen and progesterone metabolism and mammographic density changes in women randomized to postmenopausal hormone therapy: results from a pilot study. Breast Cancer Res. 2005; 7(3):R336-44. View in: PubMed

Greatly increased occurrence of breast cancers in areas of mammographically dense tissue. Breast Cancer Res. 2005; 7(5):R605-8. View in: PubMed

Urinary estrogen metabolites and their ratio among Asian American women. Cancer Epidemiol Biomarkers Prev. 2005 Jan; 14(1):221-6. View in: PubMed

Prevention of cancers of the breast, endometrium and ovary. Oncogene. 2004 Aug 23; 23(38):6379-91. View in: PubMed

Post-treatment change in serum estrone predicts mammographic percent density changes in women who received combination estrogen and progestin in the Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. J Clin Oncol. 2004 Jul 15; 22(14):2842-8. View in: PubMed

Hormonal factors and the risk of invasive ovarian cancer: a population-based case-control study. Fertil Steril. 2004 Jul; 82(1):186-95. View in: PubMed

IL-6 levels and genotype are associated with risk of young adult Hodgkin lymphoma. Blood. 2004 Apr 15; 103(8):3216-21. View in: PubMed

Maternal risk factors for testicular cancer: a population-based case-control study (UK). Cancer Causes Control. 2004 Apr; 15(3):277-83. View in: PubMed

Does mammographic density reflect ethnic differences in breast cancer incidence rates? Am J Epidemiol. Does mammographic density reflect ethnic differences in breast cancer incidence rates? Am J Epidemiol. 2004 Jan 15; 159(2):140-7. View in: PubMed

A comprehensive haplotype analysis of CYP19 and breast cancer risk: the Multiethnic Cohort. Hum Mol Genet. 2003 Oct 15; 12(20):2679-92. View in: PubMed

Green tea and risk of breast cancer in Asian Americans. Int J Cancer. 2003 Sep 10; 106(4):574-9. View in: PubMed

Mammographic density and breast cancer in three ethnic groups. Cancer Epidemiol Biomarkers Prev. 2003 Apr; 12(4):332-8. View in: PubMed

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet. 2003 Feb; 33(2):177-82. View in: PubMed

Choosing haplotype-tagging SNPS based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the Multiethnic Cohort Study. Hum Hered. 2003; 55(1):27-36. View in: PubMed

Correlation of dietary intake and colorectal cancer incidence among Mexican-American migrants: the multiethnic cohort study. Nutr Cancer. 2003; 45(2):133-47. View in: PubMed

Postmenopausal hormone therapy and change in mammographic density. J Natl Cancer Inst. 2003 Jan 01; 95(1):30-7. View in: PubMed

Adolescent and adult soy intake and risk of breast cancer in Asian-Americans. Carcinogenesis. 2002 Sep; 23(9):1491-6. View in: PubMed

Breast cancer in a multiethnic cohort in Hawaii and Los Angeles: risk factor-adjusted incidence in Japanese equals and in Hawaiians exceeds that in whites. Cancer Epidemiol Biomarkers Prev. 2002 Sep; 11(9):795-800. View in: PubMed

Effect of reproductive hormones on ovarian epithelial tumors: I. Effect on cell cycle activity. Cancer Biol Ther. 2002 May-Jun; 1(3):300-6. View in: PubMed

Steroid 5-alpha reductase type II V89L substitution is not associated with risk of prostate cancer in a multiethnic population study. Cancer Epidemiol Biomarkers Prev. 2002 Apr; 11(4):417-8. View in: PubMed

Galactose-1-phosphate uridyl transferase (GALT) genotype and phenotype, galactose consumption, and the risk of borderline and invasive ovarian cancer (United States). Cancer Causes Control. 2002 Mar; 13(2):113-20. View in: PubMed

Urinary 2-hydroxyestrone/16alpha-hydroxyestrone ratio and family history of breast cancer in premenopausal women. Breast Cancer Res Treat. 2002 Mar; 72(2):139-43. View in: PubMed

Does menopausal hormone replacement therapy interact with known factors to increase risk of breast cancer? J Clin Oncol. Does menopausal hormone replacement therapy interact with known factors to increase risk of breast cancer? J Clin Oncol. 2002 Feb 01; 20(3):699-706. View in: PubMed

Estrogen-progestin replacement therapy: regulatory action needed. Breast Cancer Res. 2002; 4(6):222-3. View in: PubMed

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