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Mimi S. Kim, MD

Associate Professor Of Clinical Pediatrics

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Overview

Research Overview

We are interested in understanding obesity and adiposity in children and adolescents with Congenital Adrenal Hyperplasia (CAH), as these youth have an increased prevalence of obesity beyond normative pediatric populations. We are also interested in various stages of development in CAH youth, from infancy through puberty. We hope to inform prevention efforts and treatment of complications through a better understanding of pathophysiology of CAH and obesity.

We seek to apply novel imaging technology to answer important questions in childhood metabolism and obesity.

Awards

  • USC: James H. Zumberge Research and Innovation Fund Individual Research Award, 2015-2016
  • The Saban Research Institute: The Saban Research Institute Innovative Pilot Project Award, 2012-2013
  • USC: SC-CTSI KL2 Mentored Research Career Development Award, 2011-2014
  • Endocrine Society: Endocrine Society Summer Research Fellowship Award for Mentoring, 2010
  • Children’s Hospital Los Angeles CTSI: Clinical Research and Career Development Award, 2009-2011
  • Endocrine Society: Women in Endocrinology Young Investigator’s Award, 2009
  • Pediatric Endocrine Society: Lawson Wilkins Pediatric Endocrinology Society Presidential Poster Session Award, 2007
  • Brown University Medical School: Dean’s Teaching Excellence Award, 2007
  • Pediatric Academic Societies: Pediatric Academic Societies’ Young Investigator’s Travel Award, 2007

Publications

  • Neural Correlates of Obesity and Inflammation in Children and Adolescents with Congenital Adrenal Hyperplasia Horm Res Paediatr. 2024 Feb 19. . View in PubMed
  • Congenital Adrenal Hyperplasia Pediatr Rev. 2024 Feb 01; 45(2):74-84. . View in PubMed
  • Cushing Syndrome in Childhood Pediatr Rev. 2024 Jan 01; 45(1):14-25. . View in PubMed
  • Differences in Hyperandrogenism Related to Early Detection of Non-Classical Congenital Adrenal Hyperplasia on Second Newborn Screen Int J Neonatal Screen. 2023 Sep 01; 9(3). . View in PubMed
  • Electrolyte abnormalities and stress dosing predict illness-related hospitalizations among infants and toddlers with congenital adrenal hyperplasia Clin Endocrinol (Oxf). 2023 04; 98(4):536-542. . View in PubMed
  • Weight Loss During Topiramate Treatment in a Severely Obese Adolescent with Congenital Adrenal Hyperplasia and Migraine J Clin Res Pediatr Endocrinol 2023 02 27; 15(1):81-85. . View in PubMed
  • Patient and Parent Perspectives on Testicular Adrenal Rest Tumors in Congenital Adrenal Hyperplasia Horm Res Paediatr. 2023; 96(5):518-522. . View in PubMed
  • Infants with Congenital Adrenal Hyperplasia Exhibit Thalamic Discrepancies in Early Brain Structure Horm Res Paediatr. 2023; 96(5):509-517. . View in PubMed
  • Altered Emotion Perception Linked to Structural Brain Differences in Youth With Congenital Adrenal Hyperplasia J Clin Endocrinol Metab. 2023 09 18; 108(10):e1134-e1146. . View in PubMed
  • Congenital Adrenal Hyperplasia and Brain Health: A Systematic Review of Structural, Functional, and Diffusion Magnetic Resonance Imaging (MRI) Investigations J Child Neurol. 2022 08; 37(8-9):758-783. . View in PubMed
  • Components of Metabolic Syndrome in Youth With Classical Congenital Adrenal Hyperplasia Front Endocrinol (Lausanne). 2022; 13:848274. . View in PubMed
  • A Unique Case of Aggressive Central Giant Cell Granuloma in a 10-Year-Old Boy With 16p1311 Microdeletion Syndrome. J Investig Med High Impact Case Rep. 2022 Jan-Dec; 10:23247096221123146. . View in PubMed
  • A Case of Prenatally Diagnosed Congenital Adrenal Hyperplasia With Brain Morphometric Differences J Investig Med High Impact Case Rep. 2022 Jan-Dec; 10:23247096221105245. . View in PubMed
  • Low Adrenomedullary Function Predicts Acute Illness in Infants With Classical Congenital Adrenal Hyperplasia J Clin Endocrinol Metab. 2022 01 01; 107(1):e264-e271. . View in PubMed
  • Hyponatremia, Metabolic Acidosis, and Abnormal Newborn Screen in a Preterm Neonate Neoreviews. 2021 11; 22(11):e767-e769. . View in PubMed
  • No evidence for a difference in 2D:4D ratio between youth with elevated prenatal androgen exposure due to congenital adrenal hyperplasia and controls Horm Behav. 2021 02; 128:104908. . View in PubMed
  • White Matter Microstructural Differences in Youth With Classical Congenital Adrenal Hyperplasia J Clin Endocrinol Metab. 2021 10 21; 106(11):3196-3212. . View in PubMed
  • Developmental Changes in Food Perception and Preference Front Psychol. 2021; 12:654200. . View in PubMed
  • Digit ratio (2D:4D) and congenital adrenal hyperplasia (CAH): Systematic literature review and meta-analysis Horm Behav. 2020 11; 126:104867. . View in PubMed
  • Patient and Caregiver Attitudes toward Disorders of Sex Development Nomenclature J Urol. 2020 10; 204(4):835-842. . View in PubMed
  • Assessment of Facial Morphologic Features in Patients With Congenital Adrenal Hyperplasia Using Deep Learning JAMA Netw Open. 2020 11 02; 3(11):e2022199. . View in PubMed
  • Early Adiposity Rebound Predicts Obesity and Adiposity in Youth with Congenital Adrenal Hyperplasia Horm Res Paediatr. 2020; 93(11-12):609-615. . View in PubMed
  • Prefrontal Cortex and Amygdala Subregion Morphology Are Associated With Obesity and Dietary Self-control in Children and Adolescents Front Hum Neurosci. 2020; 14:563415. . View in PubMed
  • Brain Differences in the Prefrontal Cortex, Amygdala, and Hippocampus in Youth with Congenital Adrenal Hyperplasia J Clin Endocrinol Metab. 2020 04 01; 105(4). . View in PubMed
  • Absence of Testicular Adrenal Rest Tumors in Newborns, Infants, and Toddlers with Classical Congenital Adrenal Hyperplasia Horm Res Paediatr. 2019; 92(3):157-161. . View in PubMed
  • Improved medical-alert ID ownership and utilization in youth with congenital adrenal hyperplasia following a parent educational intervention J Pediatr Endocrinol Metab. 2018 Jan 26; 31(2):213-219. . View in PubMed
  • Testicular Adrenal Rest Tumors in Boys and Young Adults with Congenital Adrenal Hyperplasia J Urol. 2017 03; 197(3 Pt 2):931-936. . View in PubMed
  • Carotid Intima-Media Thickness Is Associated with Increased Androgens in Adolescents and Young Adults with Classical Congenital Adrenal Hyperplasia Horm Res Paediatr. 2016; 85(4):242-9. . View in PubMed
  • Increased Abdominal Adiposity in Adolescents and Young Adults With Classical Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency J Clin Endocrinol Metab. 2015 Aug; 100(8):E1153-9. . View in PubMed
  • Presence of brown adipose tissue in an adolescent with severe primary hypothyroidism J Clin Endocrinol Metab. 2014 Sep; 99(9):E1686-90. . View in PubMed
  • Decreased adrenomedullary function in infants with classical congenital adrenal hyperplasia J Clin Endocrinol Metab. 2014 Aug; 99(8):E1597-601. . View in PubMed
  • MRI detection of brown adipose tissue with low fat content in newborns with hypothermia Magn Reson Imaging. 2014 Feb; 32(2):107-17. . View in PubMed
  • Management of congenital adrenal hyperplasia in childhood Curr Opin Endocrinol Diabetes Obes. 2012 Dec; 19(6):483-8. . View in PubMed
  • Changes in brown adipose tissue in boys and girls during childhood and pubertyJ Pediatr. 2012 Apr; 160(4):604-609. e1. . View in PubMed
  • J Clin Endocrinol Metab Clinical Characteristics of a Cohort of 244 Patients with Congenital Adrenal Hyperplasia. 2012. . View in PubMed
  • Meeting highlights: Endocrine Society, San Diego, California, June 19-22, 2010 Pediatr Endocrinol Rev. 2010 Dec; 8(2):114-22. . View in PubMed
  • A pharmacokinetic and pharmacodynamic study of delayed- and extended-release hydrocortisone (Chronocort) vsconventional hydrocortisone (Cortef) in the treatment of congenital adrenal hyperplasia. Clin Endocrinol (Oxf). 2010 Apr; 72(4):441-7. . View in PubMed
  • The phenotypic spectrum of contiguous deletion of CYP21A2 and tenascin XB: quadricuspid aortic valve and other midline defects Am J Med Genet A. 2009 Dec; 149A(12):2803-8. . View in PubMed
  • 2009 Annual Meeting of the Endocrine Society Washington DC, United States (June 10-13, 2009)–selected highlights Pediatr Endocrinol Rev. 2009 Dec; 7(2):50-8. . View in PubMed
  • Cardiovascular disease risk in adult women with congenital adrenal hyperplasia due to 21-hydroxylase deficiency Semin Reprod Med. 2009 Jul; 27(4):316-21. . View in PubMed
  • Ischemic stroke and rhabdomyolysis in a 15-year-old girl with paraganglioma due to an SDHB exon 6 (Q214X) mutation J Pediatr Endocrinol Metab. 2009 Jun; 22(6):565-71. . View in PubMed
  • Leucine restriction inhibits chondrocyte proliferation and differentiation through mechanisms both dependent and independent of mTOR signaling Am J Physiol Endocrinol Metab. 2009 Jun; 296(6):E1374-82. . View in PubMed
  • Mauriac syndrome: growth failure and type 1 diabetes mellitus Pediatr Endocrinol Rev. 2008 Aug; 5 Suppl 4:989-93. . View in PubMed
  • Immunogenetics of type 1 diabetes Horm Res. 2005; 64(4):180-8. . View in PubMed
  • Decreased whole blood factor IX activity following hemodilution with hemoglobin A-zero in-vitro Artif Cells Blood Substit Immobil Biotechnol. 1997 May; 25(3):289-95. . View in PubMed

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