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Nitin Pandey, PhD

Assistant Professor of Research Physiology and Neuroscience

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Email npandey@usc.edu
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Publications

  • Fluorescent protein tagging promotes phase separation and alters the aggregation pathway of huntingtin exon-1 J Biol Chem. 2024 Jan; 300(1):105585. . View in PubMed
  • Amplification of neurotoxic HTTex1 assemblies in human neurons Neurobiol Dis. 2021 11; 159:105517. . View in PubMed
  • Huntingtin fibrils with different toxicity, structure, and seeding potential can be interconverted Nat Commun. 2021 07 13; 12(1):4272. . View in PubMed
  • Discovery of Small Molecule Inhibitors of Huntingtin Exon 1 Aggregation by FRET-Based High-Throughput Screening in Living Cells ACS Chem Neurosci. 2020 08 05; 11(15):2286-2295. . View in PubMed
  • Lipid-modulation of membrane insertion and refolding of the apoptotic inhibitor Bcl-xL Biochim Biophys Acta Proteins Proteom. 2019 Jul – Aug; 1867(7-8):691-700. . View in PubMed
  • Structure of Membrane-Bound Huntingtin Exon 1 Reveals Membrane Interaction and Aggregation MechanismsStructure. 2019 10 01; 27(10):1570-1580. e4. . View in PubMed
  • The 17-residue-long N terminus in huntingtin controls stepwise aggregation in solution and on membranes via different mechanisms J Biol Chem. 2018 02 16; 293(7):2597-2605. . View in PubMed
  • Identification of distinct conformations associated with monomers and fibril assemblies of mutant huntingtin Hum Mol Genet. 2018 07 01; 27(13):2330-2343. . View in PubMed
  • The folding equilibrium of huntingtin exon 1 monomer depends on its polyglutamine tract J Biol Chem. 2018 12 21; 293(51):19613-19623. . View in PubMed
  • Formation and Structure of Wild Type Huntingtin Exon-1 Fibrils Biochemistry. 2017 07 18; 56(28):3579-3586. . View in PubMed
  • Effects of urea, metal ions and surfactants on the binding of baicalein with bovine serum albumin J Pharm Anal. 2016 Aug; 6(4):256-267. . View in PubMed
  • Evidence of two oxidation states of copper during aggregation of hen egg white lysozyme (HEWL) Int J Biol Macromol. 2015 May; 76:1-9. . View in PubMed
  • Copper(II) directs formation of toxic amorphous aggregates resulting in inhibition of hen egg white lysozyme fibrillation under alkaline salt-mediated conditions J Biomol Struct Dyn. 2015; 33(5):991-1007. . View in PubMed
  • Effect of temperature and solvent on fibrillation of human serum albumin Protein Pept Lett. 2015; 22(2):112-8. . View in PubMed
  • An insight into the ribonucleolytic and antiangiogenic activity of buffalo lactoferrin J Biomol Struct Dyn. 2015; 33(1):184-95. . View in PubMed
  • Crowded milieu prevents fibrillation of hen egg white lysozyme with retention of enzymatic activity J Photochem Photobiol B. 2014 Sep 05; 138:8-16. . View in PubMed
  • Effect of (-)-epigallocatechin gallate on the fibrillation of human serum albumin Int J Biol Macromol. 2014 Sep; 70:312-9. . View in PubMed
  • Fibrillation of human serum albumin shows nonspecific coordination on stoichiometric increment of Copper(II) J Biomol Struct Dyn. 2014; 32(9):1366-78. . View in PubMed
  • Disruption of human serum albumin fibrils by a static electric field Journal of Physics D: Applied Physics. 2014; 47:305401. . View in PubMed
  • J Phys Chem B. 2013 Nov 14; 117(45):13993-4000. . View in PubMed
  • Binding of hen egg white lysozyme fibrils with nucleic acids J Photochem Photobiol B. 2013 Oct 05; 127:52-60. . View in PubMed
  • Fructose restrains fibrillogenesis in human serum albumin Int J Biol Macromol. 2013 Oct; 61:424-32. . View in PubMed
  • Effect of surfactants on preformed fibrils of human serum albumin Int J Biol Macromol. 2013 Aug; 59:39-45. . View in PubMed
  • Preferential binding of fisetin to the native state of bovine serum albumin: spectroscopic and docking studies Mol Biol Rep. 2013 Apr; 40(4):3239-53. . View in PubMed
  • (-)-Epicatechin gallate prevents alkali-salt mediated fibrillogenesis of hen egg white lysozyme Int J Biol Macromol. 2013 Mar; 54:90-8. . View in PubMed
  • Prolonged glycation of hen egg white lysozyme generates non amyloidal structures PLoS One. 2013; 8(9):e74336. . View in PubMed
  • Fibrillation of hen egg white lysozyme triggers reduction of copper(II) Int J Biol Macromol. 2012 Jul-Aug; 51(1-2):1-6. . View in PubMed
  • Fibrillation in human serum albumin is enhanced in the presence of copper(II) J Phys Chem B. 2010 Aug 12; 114(31):10228-33. . View in PubMed

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