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Ulf P Flodby, PhD
Associate Professor of Research Medicine
HMR 911 Health Sciences Campus Los Angeles
+1 323 442 1106


Dr. Flodby's research interests include development of transgenic mouse and rat models for lung research, lung injury and repair of alveolar epithelium, lung stem/progenitor cells, lung ion transport and alveolar epithelial tight junction regulation.

Dr. Flodby earned his medical degree from Karolinska Institute in Stockholm, then went on to complete a fellowship at the University of Utah, Department of Human Genetics.


Wenner-Gren Foundations: Repatriation Stipend, 1998-2000

Wenner-Gren Foundations: Postdoctoral Stipend Award, 1996-1998

Swedish Cancer Society: Graduate Student Grant Award, 1996


A fluid secretion pathway unmasked by acinar-specific Tmem16A gene ablation in the adult mouse salivary gland. Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7):2263-8. View in: PubMed

Dynamic involvement of ATG5 in cellular stress responses. Cell Death Dis. 2014 Oct 23; 5:e1478. View in: PubMed

Claudin 4 knockout mice: normal physiological phenotype with increased susceptibility to lung injury. Am J Physiol Lung Cell Mol Physiol. 2014 Oct 01; 307(7):L524-36. View in: PubMed

TRIM72 is required for effective repair of alveolar epithelial cell wounding. Am J Physiol Lung Cell Mol Physiol. 2014 Sep 15; 307(6):L449-59. View in: PubMed

Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis. Am J Respir Cell Mol Biol. 2014 Aug; 51(2):210-22. View in: PubMed

Deletion of ATG5 shows a role of autophagy in salivary homeostatic control. J Dent Res. 2013 Oct; 92(10):911-7. View in: PubMed

Interactions between ß-catenin and transforming growth factor-ß signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP). J Biol Chem. 2012 Mar 02; 287(10):7026-38. View in: PubMed

Ligand-independent transforming growth factor-ß type I receptor signalling mediates type I collagen-induced epithelial-mesenchymal transition. J Pathol. 2012 Mar; 226(4):633-44. View in: PubMed

Nuclear localization of de novo thymidylate biosynthesis pathway is required to prevent uracil accumulation in DNA. J Biol Chem. 2011 Dec 23; 286(51):44015-22. View in: PubMed

Directed expression of Cre in alveolar epithelial type 1 cells. Am J Respir Cell Mol Biol. 2010 Aug; 43(2):173-8. View in: PubMed

Current Topics in Membranes. In: Claudins, Editor: A. S. L. Yu). Chapter 8. Claudins and barrier function of the lung. 2010; Volume 65:177-194. View in: PubMed

Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice. J Biol Chem. 2008 Sep 19; 283(38):25846-53. View in: PubMed

Rat aquaporin-5 4. 3-kb 5'-flanking region differentially regulates expression in salivary gland and lung in vivo. Am J Physiol Cell Physiol. 2008 Jul; 295(1):C111-20. View in: PubMed

Conserved elements within first intron of aquaporin-5 (Aqp5) function as transcriptional enhancers. Biochem Biophys Res Commun. 2007 Apr 27; 356(1):26-31. View in: PubMed

Role for ELOVL3 and fatty acid chain length in development of hair and skin function. J Biol Chem. 2004 Feb 13; 279(7):5621-9. View in: PubMed

Inactivation of the nuclear receptor coactivator RAP250 in mice results in placental vascular dysfunction. Mol Cell Biol. 2003 Feb; 23(4):1260-8. View in: PubMed

Knockout mice and steroid receptor research. Methods Mol Biol. 2001; 176:201-26. View in: PubMed

Hoxb1 controls effectors of sonic hedgehog and Mash1 signaling pathways. Development. 2000 Dec; 127(24):5343-54. View in: PubMed

Increased hepatic cell proliferation and lung abnormalities in mice deficient in CCAAT/enhancer binding protein alpha. J Biol Chem. 1996 Oct 04; 271(40):24753-60. View in: PubMed

Expression of the liver-enriched transcription factors C/EBP alpha, C/EBP beta, HNF-1, and HNF-4 in preneoplastic nodules and hepatocellular carcinoma in rat liver. Mol Carcinog. 1995 Feb; 12(2):103-9. View in: PubMed

Analysis of antibody specificity against the third variable region of the envelope glycoprotein gp120 of HIV-1 in plasma from HIV-1-positive individuals residing in Brazil. Braz J Med Biol Res. 1994 May; 27(5):1225-36. View in: PubMed

Differential patterns of expression of three C/EBP isoforms, HNF-1, and HNF-4 after partial hepatectomy in rats. Exp Cell Res. 1993 Sep; 208(1):248-56. View in: PubMed

High level activity of the mouse CCAAT/enhancer binding protein (C/EBP alpha) gene promoter involves autoregulation and several ubiquitous transcription factors. Nucleic Acids Res. 1993 Apr 25; 21(8):1735-42. View in: PubMed

Effects of mutations in glycosylation sites and disulphide bonds on processing, CD4-binding and fusion activity of human immunodeficiency virus envelope glycoproteins. J Gen Virol. 1991 Jun; 72 ( Pt 6):1269-77. View in: PubMed

In vivo stabilization of a human recombinant CD4 derivative by fusion to a serum-albumin-binding receptor. In: Modern Approaches to Vaccine Development (eds. : R. M. Chanock, et al. ) - volume 91 of Vaccines. New York, NY: Cold Spring Harbor Laboratory Press, pp. 363-368. 1991. View in: PubMed

Production and characterization of a fragment containing the HIV-gp120 binding region of CD4 using a bovine papilloma virus (BPV) vector. Arch Virol. 1990; 113(3-4):209-19. View in: PubMed

Cystein 402 of HIV gp 120 is essential for CD4-binding and resistance of gp 120 to intracellular degradation. Arch Virol. 1989; 109(3-4):269-76. View in: PubMed

Coexpression of human immunodeficiency virus envelope proteins and tat from a single simian virus 40 late replacement vector. Proc Natl Acad Sci U S A. 1988 Jan; 85(2):334-8. View in: PubMed

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