Division of Gastrointestinal and Liver Diseases

Research

Are you a patient?

The Division of Gastrointestinal and Liver Diseases published 52 peer-reviewed research papers during the period of January 1 through December 31, 2015, and nine more are in press. This body of work represents a broad range of clinical and basic research activities from nearly all of the division’s members.

Faculty Research Areas

  • Clinical and Endoscopic Management of Pancreatitis
    Gastrointestinal Malignancy
    Complex Biliary Disease
    Development of Biomarkers for Pancreatic and Gastric Cancer

  • Autoimmune and Rare Liver Diseases
    Immune mediated liver injury from checkpoint inhibitors and immunotherapy
    Drug and herbal supplement induced liver injury and hepatotoxicity
    Autoimmune hepatitis
    Primary biliary cholangitis
    Primary sclerosing cholangitis
    Cell death pathways in liver disease

  • Role of Liver Sinusoidal Endothelial Cell in Liver Injury Recovery and Liver Fibrosis
    Drug-Induced Liver Injury

  • Viral Hepatitis
    Liver Transplantation
    Complications of End Stage Liver Disease

  • Endoplasmic Reticulum (ER) Stress and Liver Disease
    Hyperhomocysteinemia
    Hepatotoxicity of HIV Drugs and Alcohol
    Tackling Alcohol Intoxication with Nanotechnology

  • Liver Transplantation
    Hepatocellular Carcinoma
    Acute Liver Failure
    Portal Hypertension

  • Drug Toxicity
    Signal Transduction
    Oxidative Stress
    Glutathione Metabolism
    Pathogenesis of Alcoholic Liver Disease
    Endoplasmic Reticulum (ER) Stress
    Mitochondrial Biogenesis

  • Hepatitis C Treatment
    Liver Transplantation
    Cirrhotic Cardiomyopathy

  • Liver Transplantation
    Acute Liver Failure
    Complications of Portal Hypertension

  • Diagnosis and Endoscopic Management of Complex Biliary and Pancreatic Disorders
    Endoscopic Ultrasound for Evaluation of Pancreatic Cysts and Malignancies
    Endoscopic Mucosal Resection and Large Colonic Polyps

  • Liver Bioengineering
    Hepatocyte Cell Biology
    Molecular Biology of Liver Diseases (Viral Hepatitis, Metabolic Liver Diseases, Cholestatic Liver Diseases)
    Molecular Virology of HBV, HCV, and HDV
    Innate Immunity
    Cytokine Biology
    Macrophage Biology and Immunobiology

    Lab site: https://sites.usc.edu/saito-lab/

  • Epithelial-Stromal Interactions in GI Tract Injury, Repair and Carcinogenesis

  • Health Maintenance in Inflammatory Bowel Disease
    Pregnancy in Inflammatory Bowel Disease
    Management of Variceal and Tumor Bleeding

  • Motility Disorders of the GI Tract

  • Gene Regulation by Oxidant Stress
    Dysregulation of Androgen Metabolism in Prostate Cancer
    Drug-Induced Liver Injury/Alcoholic Hepatitis and NAFLD

  • Mitochondrial Biogenesis in Liver Diseases
    Signal Transduction across Mitochondrial Membrane

  • Diagnosis and Treatment of Pancreatic, Esophageal, Gastric and Colorectal Cancers
    Advanced Endoscopic Management of Pancreatic Cysts, Large Common Bile Duct Stones, Complex Biliary Strictures and Large Colonic Polyps

  • Signal Transduction in Drug-Induced Hepatotoxicity, Non-Alcoholic Steatohepatitis and Alcoholic Hepatitis
    Identification of Therapeutic Target to Prevent Drug-Induced Hepatotoxicity
    Mitochondrial Biogenesis
    Oxidative Stress

    Students’ research program

  • Liver Transplantation
    Complications of Cirrhosis
    Drug-Induced Liver Injury
    Autoimmune Hepatitis
    Non-Alcoholic Steatohepatitis
    Alcoholic Liver Diseases