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Introducing Laurie DeLeve, MD. , Ph. D. , Our 2022 AASLD President. Hepatology. 2022 03; 75(3):514-517. . View in PubMed

Modulation of hepatic amyloid precursor protein and lipoprotein receptor-related protein 1 by chronic alcohol intake: Potential link between liver steatosis and amyloid-ß Front Physiol. 2022; 13:930402. . View in PubMed

The gut microbial metabolite, 3,4-dihydroxyphenylpropionic acid, alleviates hepatic ischemia/reperfusion injury via mitigation of macrophage pro-inflammatory activity in mice Acta Pharm Sin B. 2022 Jan; 12(1):182-196. . View in PubMed

Hepatic Mitochondrial SAB Deletion or Knockdown Alleviates Diet-Induced Metabolic Syndrome, Steatohepatitis, and Hepatic Fibrosis Hepatology. 2021 12; 74(6):3127-3145. . View in PubMed

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IgG:IgM Ratios of Liver Plasma Cells Reveal Similar Phenotypes of Primary Biliary Cholangitis With and Without Features of Autoimmune Hepatitis Clin Gastroenterol Hepatol. 2021 02; 19(2):397-399. . View in PubMed

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Markedly Elevated Serum Aspartate Aminotransferase to Alanine Aminotransferase Ratio: A Clue to Hepatic Neoplasia Hepatol Commun. 2020 Jul; 4(7):1099-1101. . View in PubMed

Acetaminophen Hepatotoxicity: Strong Offense and Weakened Defense Hepatology. 2020 05; 71(5):1530-1532. . View in PubMed

Intestinal Epithelial Chemokine (C-C Motif) Ligand 7 Overexpression Enhances Acetaminophen-Induced Hepatotoxicity in Mice Am J Pathol. 2020 01; 190(1):57-67. . View in PubMed

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Endoplasmic Reticulum Stress-Induced Upregulation of STARD1 Promotes Acetaminophen-Induced Acute Liver Failure Gastroenterology. 2019 08; 157(2):552-568. . View in PubMed

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Expression of mitochondrial membrane-linked SAB determines severity of sex-dependent acute liver injury J Clin Invest. 2019 12 02; 129(12):5278-5293. . View in PubMed

The Regulation of JNK Signaling Pathways in Cell Death through the Interplay with Mitochondrial SAB and Upstream Post-Translational Effects Int J Mol Sci. 2018 Nov 20; 19(11). . View in PubMed

Niacin-Induced Anicteric Microvesicular Steatotic Acute Liver Failure Hepatol Commun. 2018 Nov; 2(11):1293-1298. . View in PubMed

Herb-Induced Liver Injury: A Global Concern Chin J Integr Med. 2018 Sep; 24(9):643-644. . View in PubMed

Glycycoumarin protects mice against acetaminophen-induced liver injury predominantly via activating sustained autophagy Br J Pharmacol. 2018 10; 175(19):3747-3757. . View in PubMed

Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in mice J Hepatol. 2018 07; 69(1):51-59. . View in PubMed

New insights into the role and mechanism of c-Jun-N-terminal kinase signaling in the pathobiology of liver diseases Hepatology. 2018 05; 67(5):2013-2024. . View in PubMed

The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading Redox Biol. 2018 04; 14:164-177. . View in PubMed

Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or Necrosis Int J Mol Sci. 2017 May 09; 18(5). . View in PubMed

Prediction of histologic alcoholic hepatitis based on clinical presentation limits the need for liver biopsy Hepatol Commun. 2017 12; 1(10):1070-1084. . View in PubMed

Heparan sulfate promotes recovery from acute liver injury: Inhibition of progressive cell death or enhanced regeneration? Hepatology. 2017 11; 66(5):1381-1383.. View in PubMed

Death and liver transplantation within 2 years of onset of drug-induced liver injury Hepatology. 2017 10; 66(4):1275-1285. . View in PubMed

Protective role of p53 in acetaminophen hepatotoxicity Free Radic Biol Med. 2017 05; 106:111-117. . View in PubMed

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The role of MAP2 kinases and p38 kinase in acute murine liver injury models Cell Death Dis. 2017 06 29; 8(6):e2903. . View in PubMed

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Antcin H Protects Against Acute Liver Injury Through Disruption of the Interaction of c-Jun-N-Terminal Kinase with Mitochondria Antioxid Redox Signal. 2017 02 10; 26(5):207-220. . View in PubMed

HLA-B*57:01 Confers Susceptibility to Pazopanib-Associated Liver Injury in Patients with Cancer Clin Cancer Res. 2016 Mar 15; 22(6):1371-7. . View in PubMed

Mechanisms of adaptation and progression in idiosyncratic drug induced liver injury, clinical implications Liver Int. 2016 Feb; 36(2):158-65. . View in PubMed

Competing Mechanistic Hypotheses of Acetaminophen-Induced Hepatotoxicity Challenged by Virtual Experiments PLoS Comput Biol. 2016 12; 12(12):e1005253. . View in PubMed

The many faces of RIPK3: What about NASH? Hepatology. 2016 11; 64(5):1411-1413.. View in PubMed

Definition and risk factors for chronicity following acute idiosyncratic drug-induced liver injury J Hepatol. 2016 09; 65(3):532-42. . View in PubMed

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c-Jun N-terminal kinase mediates mouse liver injury through a novel Sab (SH3BP5)-dependent pathway leading to inactivation of intramitochondrial Src Hepatology. 2016 06; 63(6):1987-2003. . View in PubMed

Is Sensitivity the Key Measure to Predict Acute Liver Failure in Drug-Induced Liver Injury Patients? Clin Gastroenterol Hepatol. 2016 06; 14(6):918.. View in PubMed

Knockdown of RIPK1 Markedly Exacerbates Murine Immune-Mediated Liver Injury through Massive Apoptosis of Hepatocytes, Independent of Necroptosis and Inhibition of NF-? B. J Immunol. 2016 10 15; 197(8):3120-3129.. View in PubMed

A murder mystery in the liver: who done it and how? J Clin Invest. 2016 11 01; 126(11):4068-4071.. View in PubMed

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Lysosomal Cholesterol Accumulation Sensitizes To Acetaminophen Hepatotoxicity by Impairing Mitophagy Sci Rep. 2015 Dec 11; 5:18017. . View in PubMed

Alcoholic foamy degeneration and alcoholic fatty liver with jaundice: Often overlooked causes of jaundice and hepatic decompensation that can mimic alcoholic hepatitis Clin Liver Dis (Hoboken). 2015 Dec; 6(6):145-148. . View in PubMed

Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis Hepatology. 2015 Dec; 62(6):1847-57. . View in PubMed

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Inhibition of immune tolerance unmasks drug-induced allergic hepatitis Hepatology. 2015 Aug; 62(2):346-8. . View in PubMed

Targeting signal transduction pathways which regulate necrosis in acetaminophen hepatotoxicity J Hepatol. 2015 Jul; 63(1):5-7. . View in PubMed

Characterisation of liver chemistry abnormalities associated with pazopanib monotherapy: a systematic review and meta-analysis of clinical trials in advanced cancer patients Eur J Cancer. 2015 Jul; 51(10):1293-302. . View in PubMed

Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity J Hepatol. 2015 Jun; 62(6):1367-74. . View in PubMed

Reply: To PMID 24704526 Gastroenterology. 2015 Feb; 148(2):452-3. . View in PubMed

Acid sphingomyelinase-ceramide system in steatohepatitis: a novel target regulating multiple pathways J Hepatol. 2015 Jan; 62(1):219-33. . View in PubMed

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In vitro assays of mitochondrial function/dysfunction Clin Pharmacol Ther. 2014 Dec; 96(6):665-8. . View in PubMed

The clinical liver safety assessment best practices workshop: rationale, goals, accomplishments and the future Drug Saf. 2014 Nov; 37 Suppl 1:S1-7. . View in PubMed

ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis J Hepatol. 2014 Nov; 61(5):1126-34. . View in PubMed

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Cell death and cell death responses in liver disease: mechanisms and clinical relevanceGastroenterology. 2014 Oct; 147(4):765-783. e4. . View in PubMed

Use of Hy's law and a new composite algorithm to predict acute liver failure in patients with drug-induced liver injuryGastroenterology. 2014 Jul; 147(1):109-118. e5. . View in PubMed

Respiratory substrates regulate S-nitrosylation of mitochondrial proteins through a thiol-dependent pathway Chem Res Toxicol. 2014 May 19; 27(5):794-804. . View in PubMed

Protein kinase C (PKC) participates in acetaminophen hepatotoxicity through c-jun-N-terminal kinase (JNK)-dependent and -independent signaling pathways Hepatology. 2014 Apr; 59(4):1543-1554. . View in PubMed

JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death Cell Death Dis. 2014 Jan 09; 5:e989. . View in PubMed

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ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading J Hepatol. 2013 Oct; 59(4):805-13. . View in PubMed

Role of Mitochondria in Alcoholic Liver Disease Curr Pathobiol Rep. 2013 Sep 01; 1(3):159-168. . View in PubMed

Avoiding idiosyncratic DILI: two is better than one Hepatology. 2013 Jul; 58(1):15-7. . View in PubMed

Mitochondrial glutathione: features, regulation and role in disease Biochim Biophys Acta. 2013 May; 1830(5):3317-28. . View in PubMed

Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria Trends Pharmacol Sci. 2013 Apr; 34(4):243-53. . View in PubMed

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Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis J Hepatol. 2012 Oct; 57(4):852-9. . View in PubMed

Interstrain differences in liver injury and one-carbon metabolism in alcohol-fed mice Hepatology. 2012 Jul; 56(1):130-9. . View in PubMed

Dealing with stress Hepatology. 2012 Jan; 55(1):3-13. . View in PubMed

c-Jun N-terminal kinase (JNK)-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice J Biol Chem. 2011 Oct 07; 286(40):35071-8. . View in PubMed

Recurrent drug-induced liver injury (DILI) with different drugs in the Spanish Registry: the dilemma of the relationship to autoimmune hepatitis J Hepatol. 2011 Oct; 55(4):820-7. . View in PubMed

Differential effect of gender on hepatic fat Pediatr Radiol. 2011 Sep; 41(9):1146-53. . View in PubMed

Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice Hepatology. 2011 Jul; 54(1):229-39. . View in PubMed

Genetic variation in UGT1A1 typical of Gilbert syndrome is associated with unconjugated hyperbilirubinemia in patients receiving tocilizumab Pharmacogenet Genomics. 2011 Jul; 21(7):365-74. . View in PubMed

Role of cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 3 (CRTC3) in the initiation of mitochondrial biogenesis and stress response in liver cells J Biol Chem. 2011 Jun 24; 286(25):22047-54. . View in PubMed

Case definition and phenotype standardization in drug-induced liver injury Clin Pharmacol Ther. 2011 Jun; 89(6):806-15. . View in PubMed

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Metabonomic investigation of liver profiles of nonpolar metabolites obtained from alcohol-dosed rats and mice using high mass accuracy MSn analysis J Proteome Res. 2011 Feb 04; 10(2):705-13. . View in PubMed

Regulation of mitochondrial glutathione redox status and protein glutathionylation by respiratory substrates J Biol Chem. 2010 Dec 17; 285(51):39646-54. . View in PubMed

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Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1 J Biol Chem. 2010 Mar 12; 285(11):8244-55. . View in PubMed

Differences in betaine-homocysteine methyltransferase expression, endoplasmic reticulum stress response, and liver injury between alcohol-fed mice and rats Hepatology. 2010 Mar; 51(3):796-805. . View in PubMed

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Redox regulation of tumor necrosis factor signaling Antioxid Redox Signal. 2009 Sep; 11(9):2245-63. . View in PubMed

Phenotypic characterization of idiosyncratic drug-induced liver injury: the influence of age and sex Hepatology. 2009 Jun; 49(6):2001-9. . View in PubMed

Genetic risk factors for portopulmonary hypertension in patients with advanced liver disease Am J Respir Crit Care Med. 2009 May 01; 179(9):835-42. . View in PubMed

Glutathione in liver diseases and hepatotoxicity Mol Aspects Med. 2009 Feb-Apr; 30(1-2):29-41. . View in PubMed

How to protect against acetaminophen: don't ask for JUNK Gastroenterology. 2008 Oct; 135(4):1047-51. . View in PubMed

Impact of hepatopulmonary syndrome on quality of life and survival in liver transplant candidates Gastroenterology. 2008 Oct; 135(4):1168-75. . View in PubMed

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Regulation of H(2)O(2)-induced necrosis by PKC and AMP-activated kinase signaling in primary cultured hepatocytes Am J Physiol Cell Physiol. 2008 Jul; 295(1):C50-63. . View in PubMed

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Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes Hepatology. 2007 Nov; 46(5):1586-96. . View in PubMed

Glutathione depletion down-regulates tumor necrosis factor alpha-induced NF-kappaB activity via IkappaB kinase-dependent and -independent mechanisms J Biol Chem. 2007 Oct 05; 282(40):29470-81. . View in PubMed

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Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium Am J Clin Nutr. 2007 Jul; 86(1):14-24. . View in PubMed

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Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model J Hepatol. 2006 Nov; 45(5):717-24. . View in PubMed

Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum J Gastroenterol Hepatol. 2006 Oct; 21 Suppl 3:S7-9. . View in PubMed

Hydrogen peroxide and redox modulation sensitize primary mouse hepatocytes to TNF-induced apoptosis Free Radic Biol Med. 2006 Aug 15; 41(4):627-39. . View in PubMed

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Neutrophil depletion protects against murine acetaminophen hepatotoxicity Hepatology. 2006 Jun; 43(6):1220-30. . View in PubMed

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Role of CHOP in hepatic apoptosis in the murine model of intragastric ethanol feeding Alcohol Clin Exp Res. 2005 Aug; 29(8):1496-503. . View in PubMed

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Severe hepatotoxicity associated with the use of weight loss diet supplements containing ma huang or usnic acid J Hepatol. 2004 Dec; 41(6):1062-4. . View in PubMed

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The thiol sensitivity of glutathione transport in sidedness-sorted basolateral liver plasma membrane and in Oatp1-expressing HeLa cell membrane Mol Pharmacol. 2002 Feb; 61(2):425-35. . View in PubMed

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Bidirectional membrane transport of intact glutathione in Hep G2 cells Am J Physiol. 1993 Dec; 265(6 Pt 1):G1128-34. . View in PubMed

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Identification and purification of a human liver cytosolic tocopherol binding protein Protein Expr Purif. 1993 Oct; 4(5):382-9. . View in PubMed

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Selective induction by phenobarbital of the electrogenic transport of glutathione and organic anions in rat liver canalicular membrane vesicles J Biol Chem. 1993 May 25; 268(15):10836-41. . View in PubMed

Expression of rat liver reduced glutathione transport in Xenopus laevis oocytes J Biol Chem. 1993 Feb 05; 268(4):2324-8. . View in PubMed

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Insulin and glucocorticoid dependence of hepatic gamma-glutamylcysteine synthetase and glutathione synthesis in the ratStudies in cultured hepatocytes and in vivo. J Clin Invest. 1992 Aug; 90(2):524-32. . View in PubMed

The relationship between biliary secretion of bilirubin and glutathione in the rat Gastroenterol Jpn. 1992 Jun; 27(3):369-73. . View in PubMed

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Canalicular transport of reduced glutathione in normal and mutant Eisai hyperbilirubinemic rats J Biol Chem. 1992 Jan 25; 267(3):1667-73. . View in PubMed

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Glutathione metabolism and its role in hepatotoxicity Pharmacol Ther. 1991 Dec; 52(3):287-305. . View in PubMed

Effect of indomethacin on the uptake, metabolism and excretion of 3-oxocholic acid: studies in isolated hepatocytes and perfused rat liver Biochim Biophys Acta. 1991 Jul 30; 1084(3):247-50. . View in PubMed

Hormone-mediated down-regulation of hepatic glutathione synthesis in the rat J Clin Invest. 1991 Jul; 88(1):260-9. . View in PubMed

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The use of monochlorobimane to determine hepatic GSH levels and synthesis Anal Biochem. 1990 Nov 01; 190(2):212-9. . View in PubMed

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Hormonal regulation of glutathione efflux J Biol Chem. 1990 Sep 25; 265(27):16088-95. . View in PubMed

Evidence for carrier-mediated transport of glutathione across the blood-brain barrier in the rat J Clin Invest. 1990 Jun; 85(6):2009-13. . View in PubMed

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Oxidation and reduction of bile acid precursors by rat hepatic 3 alpha-hydroxysteroid dehydrogenase and inhibition by bile acids and indomethacin Biochim Biophys Acta. 1990 Apr 02; 1043(2):153-6. . View in PubMed

Relationship between the newly identified bile acid binder and bile acid oxidoreductases in human liver J Biol Chem. 1990 Feb 05; 265(4):2132-6. . View in PubMed

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Effects of chronic ethanol feeding on rat hepatocytic glutathioneRelationship of cytosolic glutathione to efflux and mitochondrial sequestration. J Clin Invest. 1989 Apr; 83(4):1247-52. . View in PubMed

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Effect of membrane potential and cellular ATP on glutathione efflux from isolated rat hepatocytes Am J Physiol. 1988 Oct; 255(4 Pt 1):G403-8. . View in PubMed

Inhibition of glutathione efflux in the perfused rat liver and isolated hepatocytes by organic anions and bilirubinKinetics, sidedness, and molecular forms. J Clin Invest. 1988 Aug; 82(2):608-16. . View in PubMed

Comparison of the effects of bile acids and GSH on the fluorescence of bound 1-anilino-8-naphthalene sulfonate and the enzymatic activity of cationic and neutral human hepatic GSH S-transferases Biochim Biophys Acta. 1988 Apr 28; 954(1):37-43. . View in PubMed

Comparison of the binding sites of GSH S-transferases of the Ya- and Yb-subunit classes: effect of glutathione on the binding of bile acids J Lipid Res. 1988 Mar; 29(3):279-86. . View in PubMed

Effect of age on the sinusoidal release of hepatic glutathione from the perfused rat liver Biochem Pharmacol. 1987 Nov 15; 36(22):4015-7. . View in PubMed

Cyclical oxidation-reduction of the C3 position on bile acids catalyzed by 3 alpha-hydroxysteroid dehydrogenaseII. Studies in the prograde and retrograde single-pass, perfused rat liver and inhibition by indomethacin. J Clin Invest. 1987 Sep; 80(3):861-6. . View in PubMed

Cyclical oxidation-reduction of the C3 position on bile acids catalyzed by rat hepatic 3 alpha-hydroxysteroid dehydrogenaseI. Studies with the purified enzyme, isolated rat hepatocytes, and inhibition by indomethacin. J Clin Invest. 1987 Sep; 80(3):852-60. . View in PubMed

Effect of chronic ethanol feeding on rat hepatocytic glutathioneCompartmentation, efflux, and response to incubation with ethanol. J Clin Invest. 1987 Jul; 80(1):57-62. . View in PubMed

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Trans-stimulation and driving forces for GSH transport in sinusoidal membrane vesicles from rat liver Biochem Biophys Res Commun. 1987 Feb 27; 143(1):377-82. . View in PubMed

3 alpha-hydroxysteroid dehydrogenase activity of the Y' bile acid binders in rat liver cytosolIdentification, kinetics, and physiologic significance. J Clin Invest. 1987 Feb; 79(2):427-34. . View in PubMed

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Binding of bile acids, oleic acid, and organic anions by rat and human hepatic Z protein Arch Biochem Biophys. 1986 Nov 15; 251(1):385-92. . View in PubMed

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Mechanism of inhibition of glutathione efflux by methionine from isolated rat hepatocytes Am J Physiol. 1986 Sep; 251(3 Pt 1):G354-61. . View in PubMed

Comparison of the affinities of newly identified human bile acid binder and cationic glutathione S-transferase for bile acids J Lipid Res. 1986 Jun; 27(6):652-7. . View in PubMed

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Organic anion-binding by human hepatic GSH S-transferases Biochem Pharmacol. 1986 Jan 15; 35(2):354-6. . View in PubMed

Gamma-glutamylcysteine: a substrate for glutathione S-transferases Biochem Pharmacol. 1985 Oct 15; 34(20):3643-7. . View in PubMed

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Identification and partial purification of a unique phenolic steroid sulphotransferase in rat liver cytosol Biochem J. 1984 Dec 15; 224(3):947-53. . View in PubMed

Identification and purification of a 36 kDa bile acid binder in human hepatic cytosol FEBS Lett. 1984 Nov 05; 177(1):31-5. . View in PubMed

Comparison of the binding affinities of five forms of rat glutathione S-transferases for bilirubin, sulfobromophthalein and hematin Biochem Pharmacol. 1984 Nov 01; 33(21):3511-3. . View in PubMed

Evidence for a common high affinity binding site on glutathione S-transferase B for lithocholic acid and bilirubin J Lipid Res. 1984 Nov; 25(11):1177-83. . View in PubMed

Comparison of binding of thyroid hormone analogues to hepatic organic anion binding proteins Biochim Biophys Acta. 1984 Sep 28; 801(2):184-8. . View in PubMed

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Inhibition of glutathione efflux from isolated rat hepatocytes by methionine J Biol Chem. 1984 Aug 10; 259(15):9355-8. . View in PubMed

Quantitation and characterization of a newly described organic anion binder by radioimmunoassay Biochim Biophys Acta. 1984 Jul 30; 800(2):171-7. . View in PubMed

Binding of glutathione by rat liver cytosol Pharmacology. 1984; 28(2):61-6. . View in PubMed

Newly identified bile acid binders in rat liver cytosolPurification and comparison with glutathione S-transferases. J Biol Chem. 1983 Mar 25; 258(6):3602-7. . View in PubMed

Factors influencing the efflux of hepatic glutathione into bile in rats J Pharmacol Exp Ther. 1983 Jan; 224(1):141-7. . View in PubMed

Newly identified organic anion-binding proteins in rat liver cytosol Biochim Biophys Acta. 1982 Dec 20; 709(2):342-52. . View in PubMed

Propylthiouracil treatment for alcoholic hepatitis: should it and does it work? Gastroenterology. 1982 Jun; 82(6):1468-71.. View in PubMed

Identification of hepatic Z-protein in a marine elasmobranch, Platyrhinoides triseriata Biochem J. 1982 May 01; 203(2):377-81. . View in PubMed

Glutathione S-transferases in elasmobranch liverMolecular heterogeneity, catalytic and binding properties, and purification. Biochem J. 1981 Dec 01; 199(3):749-56. . View in PubMed

The importance and regulation of hepatic glutathione Yale J Biol Med. 1981 Nov-Dec; 54(6):497-502. . View in PubMed

Inhibition of rat hepatic thyroxine 5'-monodeiodinase by propylthiouracil: relation to site of interaction of thyroxine and glutathione J Endocrinol Invest. 1981 Oct-Dec; 4(4):379-87. . View in PubMed

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Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis Hepatology. 1981 Sep-Oct; 1(5):431-5. . View in PubMed

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Rapid oxidation in vitro of endogenous and exogenous glutathione in bile of rats J Biol Chem. 1981 Mar 10; 256(5):2115-7. . View in PubMed

Direct protection against acetaminophen hepatotoxicity by propylthiouracilIn vivo and in vitro studies in rats and mice. J Clin Invest. 1981 Mar; 67(3):688-95. . View in PubMed

Glutathione-dependent thyroxine 5'-monodeiodination modulates growth hormone production by cultured nonthyrotropic rat pituitary cells Endocrinology. 1981 Mar; 108(3):970-6. . View in PubMed

Extrahepatic obstruction in chronic alcoholic pancreatitis Alcohol Clin Exp Res. 1981 Jan; 5(1):110-8. . View in PubMed

Liver histopathology in chronic common bile duct stenosis due to chronic alcoholic pancreatitis Hepatology. 1981 Jan-Feb; 1(1):65-72. . View in PubMed

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Effect of pyridoxine deficiency on serum and liver transaminases in experimental liver injury in the rat Gastroenterology. 1980 Sep; 79(3):545-9. . View in PubMed

Estimation of glutathione in rat liver by reversed-phase high-performance liquid chromatography: separation from cysteine and gamma-glutamylcysteine J Chromatogr. 1980 Jun 27; 194(3):424-8. . View in PubMed

Bile acid tolerance tests: rationale Gastroenterology. 1980 Jun; 78(6):1654-5. . View in PubMed

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PropylthiouracilA substrate for the glutathione S-transferases that competes with glutathione. J Biol Chem. 1980 Apr 25; 255(8):3508-13. . View in PubMed

Binding of ethacrynic acid to hepatic glutathione S-transferases in vivo in the rat Biochem Pharmacol. 1980 Apr 15; 29(8):1205-8. . View in PubMed

Effect of salicylates and phenobarbital on hepatic glutathione in the rat J Pharmacol Exp Ther. 1980 Feb; 212(2):240-5. . View in PubMed

Common bile duct stenosis from chronic pancreatitis: a clinical and pathologic spectrum Medicine (Baltimore). 1979 Nov; 58(6):385-412. . View in PubMed

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Aplastic anemia associated with type B viral hepatitis Arch Intern Med. 1978 Oct; 138(10):1557-8. . View in PubMed

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Obstructive jaundice caused by hepatocellular carcinomaReport of three cases. Am J Dig Dis. 1978 Jul; 23(7):609-17. . View in PubMed

The effect of phenobarbital, probenecid and diethyl maleate on the pharmaco-kinetics and biliary excretion of ethacrynic acid in the rat J Pharmacol Exp Ther. 1978 May; 205(2):471-9. . View in PubMed

Glutathione S-transferase in human lymphoid cell lines and fractionated peripheral leucocytes Biochem J. 1978 Mar 01; 169(3):465-70. . View in PubMed

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Effect of dietary phenobarbital, 3,4-benzo(alpha)pyrene and 3-methylcholanthrene on hepatic, intestinal and renal glutathione s-transferase activities in the rat Biochem Pharmacol. 1978; 27(8):1284-7. . View in PubMed

Endocrine and metabolic alterations with food and water deprivation Am J Clin Nutr. 1977 Dec; 30(12):1953-62. . View in PubMed

Interaction of azathioprine and glutathione in the liver of the rat J Pharmacol Exp Ther. 1977 Mar; 200(3):479-86. . View in PubMed

The glutathione S-transferases of the small intestine in the rat Cancer Res. 1977 Mar; 37(3):788-91. . View in PubMed

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Comparison of renal and hepatic glutathione S-transferases in the rat Biochem J. 1976 Aug 15; 158(2):243-8. . View in PubMed

Drug induction and sex differences of renal glutathione S-transferases in the rat Biochem J. 1975 Aug; 150(2):259-62. . View in PubMed

Hepatic glutathione S-transferases: identification by gel filtration and in vitro inhibition by organic anions Proc Soc Exp Biol Med. 1975 May; 149(1):234-7. . View in PubMed

Drug induction of hepatic glutathione S-transferases in male and female rats* Biochem J. 1975 Feb; 146(2):351-6. . View in PubMed

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Role of hepatic anion-binding protein in bromsulphthalein conjugation J Exp Med. 1973 Aug 01; 138(2):483-7. . View in PubMed

Postprandial serum bile acid for the detection of hepatobiliary disease JAMA. 1973 Jul 16; 225(3):292-3. . View in PubMed

Hepatobiliary diseases associated with serum antimitochondrial antibody (AMA) Am J Med. 1973 Jun; 54(6):725-30. . View in PubMed

Quantitative analysis of unconjugated and conjugated bile acids in duodenal fluid by densitometry after paper electrophoresis J Lipid Res. 1973 Mar; 14(2):224-8. . View in PubMed

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