Kinji Asahina

Kinji Asahina

Associate Professor of Research Pathology
MMR402 1333 San Pablo Street Health Sciences Campus Los Angeles

Cholesterol-binding translocator protein TSPO regulates steatosis and bile acid synthesis in nonalcoholic fatty liver disease iScience. 2021 May 21; 24(5):102457. . View in PubMed

Inhibition of Stearoyl-CoA Desaturase Induces the Unfolded Protein Response in Pancreatic Tumors and Suppresses Their Growth Pancreas. 2021 Feb 01; 50(2):219-226. . View in PubMed

Urea-based amino sugar agent clears murine liver and preserves protein fluorescence and lipophilic dyes Biotechniques. 2021 Jan 20. . View in PubMed

Prominin-1-expressing hepatic progenitor cells induce fibrogenesis in murine cholestatic liver injury Physiol Rep. 2020 07; 8(14):e14508. . View in PubMed

Development of Capsular Fibrosis Beneath the Liver Surface in Humans and Mice Hepatology. 2020 01; 71(1):291-305. . View in PubMed

Moderate alcohol intake promotes pancreatic ductal adenocarcinoma development in mice expressing oncogenic Kras Am J Physiol Gastrointest Liver Physiol. 2020 02 01; 318(2):G265-G276. . View in PubMed

Isolation of a unique hepatic stellate cell population expressing integrin a8 from embryonic mouse livers Dev Dyn. 2018 Jun; 247(6):867-881. . View in PubMed

Hepatic Prominin-1 expression is associated with biliary fibrosis Surgery. 2017 05; 161(5):1266-1272. . View in PubMed

Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers J Hepatol. 2016 May; 64(5):1137-1146. . View in PubMed

The Role of Mesothelial Cells in Liver Development, Injury, and Regeneration Gut Liver. 2016 Mar; 10(2):166-76. . View in PubMed

Role of TGF-ß signaling in differentiation of mesothelial cells to vitamin A-poor hepatic stellate cells in liver fibrosis Am J Physiol Gastrointest Liver Physiol. 2016 Feb 15; 310(4):G262-72. . View in PubMed

Activation of hepatic stellate cell in Pten null liver injury model Fibrogenesis Tissue Repair. 2016; 9:8. . View in PubMed

Myofibroblastic Conversion and Regeneration of Mesothelial Cells in Peritoneal and Liver Fibrosis Am J Pathol. 2015 Dec; 185(12):3258-73. . View in PubMed

MACS Isolation and Culture of Mouse Liver Mesothelial Cells Bio Protoc. 2015 Jul 05; 3(13). . View in PubMed

Expansion of prominin-1-expressing cells in association with fibrosis of biliary atresia Hepatology. 2014 Sep; 60(3):941-53. . View in PubMed

TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis J Clin Invest. 2014 Aug; 124(8):3566-78. . View in PubMed

Mesodermal mesenchymal cells give rise to myofibroblasts, but not epithelial cells, in mouse liver injury Hepatology. 2014 Jul; 60(1):311-22. . View in PubMed

Hepatic stellate cells in liver development, regeneration, and cancer J Clin Invest. 2013 May; 123(5):1902-10. . View in PubMed

Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver injury Proc Natl Acad Sci U S A. 2013 Feb 05; 110(6):2324-9. . View in PubMed

Hepatology. 2012 Apr; 55(4):1271-81. . View in PubMed

Hepatic stellate cell-derived delta-like homolog 1 (DLK1) protein in liver regeneration J Biol Chem. 2012 Mar 23; 287(13):10355-10367. . View in PubMed

Hepatic stellate cells mediate differentiation of dendritic cells from monocytes J Med Dent Sci. 2012 Mar 13; 59(1):43-52. . View in PubMed

Hepatic stellate cell progenitor cells J Gastroenterol Hepatol. 2012 Mar; 27 Suppl 2:80-4. . View in PubMed

Morphogens and hepatic stellate cell fate regulation in chronic liver disease J Gastroenterol Hepatol. 2012 Mar; 27 Suppl 2:94-8. . View in PubMed

Epigenetic cell fate regulation of hepatic stellate cells Hepatol Res. 2011 Jul; 41(7):675-82. . View in PubMed

15th International Symposium on Cells of the Hepatic Sinusoid, 2010 Liver Int. 2011 Jul; 31(6):762-72. . View in PubMed

Septum transversum-derived mesothelium gives rise to hepatic stellate cells and perivascular mesenchymal cells in developing mouse liver Hepatology. 2011 Mar; 53(3):983-95. . View in PubMed

A novel method of mouse ex utero transplantation of hepatic progenitor cells into the fetal liver Biochem Biophys Res Commun. 2009 Apr 03; 381(2):276-82. . View in PubMed

Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development Hepatology. 2009 Mar; 49(3):998-1011. . View in PubMed

Effect of poly(N-vinyl-pyrrolidone)-block-poly(D,L-lactide) as coating agent on the opsonization, phagocytosis, and pharmacokinetics of biodegradable nanoparticles Biomacromolecules. 2009 Feb 09; 10(2):408-16. . View in PubMed

Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog Proc Natl Acad Sci U S A. 2009 Feb 03; 106(5):1548-53. . View in PubMed

Vascular endothelial growth factor promotes proliferation and function of hepatocyte-like cells in embryoid bodies formed from mouse embryonic stem cells J Hepatol. 2008 Jun; 48(6):962-73. . View in PubMed

Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis Am J Physiol Gastrointest Liver Physiol. 2008 Jan; 294(1):G39-49. . View in PubMed

Involvement of CCAAT/enhancer binding protein-beta (C/EBPbeta) in epigenetic regulation of mouse methionine adenosyltransferase 1A gene expression Int J Biochem Cell Biol. 2008; 40(9):1956-69. . View in PubMed

Hepatic progenitor cells in the mouse extrahepatic bile duct after a bile duct ligation Stem Cells Dev. 2007 Dec; 16(6):979-87. . View in PubMed

Developmental pluripotency-associated 4 (DPPA4) localized in active chromatin inhibits mouse embryonic stem cell differentiation into a primitive ectoderm lineage J Biol Chem. 2007 Nov 09; 282(45):33034-42. . View in PubMed

Characterization of vitamin A-storing cells in mouse fibrous kidneys using Cygb/STAP as a marker of activated stellate cells Arch Histol Cytol. 2007 Jul; 70(2):95-106. . View in PubMed

Twist relates to tubular epithelial-mesenchymal transition and interstitial fibrogenesis in the obstructed kidney J Histochem Cytochem. 2007 Jul; 55(7):661-73. . View in PubMed

Identification of vitamin A-free cells in a stellate cell-enriched fraction of normal rat liver as myofibroblasts Histochem Cell Biol. 2007 Feb; 127(2):161-74. . View in PubMed

Human cord blood cells transplanted into chronically damaged liver exhibit similar characteristics to functional hepatocytes Transplant Proc. 2007 Jan-Feb; 39(1):240-3. . View in PubMed

Embryonic stem cells: hepatic differentiation and regenerative medicine for the treatment of liver disease Curr Stem Cell Res Ther. 2006 May; 1(2):139-56. . View in PubMed

Multiplicative mononuclear small hepatocytes in adult rat liver: their isolation as a homogeneous population and localization to periportal zone Biochem Biophys Res Commun. 2006 Apr 21; 342(4):1160-7. . View in PubMed

Differential involvement of phosphatidylinositol 3-kinase-related protein kinases in hyperphosphorylation of replication protein A2 in response to replication-mediated DNA double-strand breaks Genes Cells. 2006 Mar; 11(3):237-46. . View in PubMed

Generation of hybrid hepatocytes by cell fusion from monkey embryoid body cells in the injured mouse liver Histochem Cell Biol. 2006 Mar; 125(3):247-57. . View in PubMed

Phosphorylation of histone H2AX at M phase in human cells without DNA damage response Biochem Biophys Res Commun. 2005 Oct 28; 336(3):807-12. . View in PubMed

Efficient in vivo xenogeneic retroviral vector-mediated gene transduction into human hepatocytes Hum Gene Ther. 2005 Oct; 16(10):1168-74. . View in PubMed

Enrichment of hepatocytes differentiated from mouse embryonic stem cells as a transplantable source Transplantation. 2005 Mar 15; 79(5):550-7. . View in PubMed

Teratoma formation and hepatocyte differentiation in mouse liver transplanted with mouse embryonic stem cell-derived embryoid bodies Transplant Proc. 2005 Jan-Feb; 37(1):285-6. . View in PubMed

Isolation of hepatocyte-like cells from mouse embryoid body cells Transplant Proc. 2005 Jan-Feb; 37(1):299-300. . View in PubMed

Hepatocyte differentiation from embryonic stem cells and umbilical cord blood cells J Hepatobiliary Pancreat Surg. 2005; 12(3):196-202. . View in PubMed

Expression of the liver-specific gene Cyp7a1 reveals hepatic differentiation in embryoid bodies derived from mouse embryonic stem cells Genes Cells. 2004 Dec; 9(12):1297-308. . View in PubMed

Near completely humanized liver in mice shows human-type metabolic responses to drugs Am J Pathol. 2004 Sep; 165(3):901-12. . View in PubMed

Characterization of human stellate cell activation-associated protein and its expression in human liver Biochim Biophys Acta. 2002 Sep 27; 1577(3):471-5. . View in PubMed

Pleiotrophin/heparin-binding growth-associated molecule as a mitogen of rat hepatocytes and its role in regeneration and development of liver Am J Pathol. 2002 Jun; 160(6):2191-205. . View in PubMed

Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells J Biol Chem. 2001 Jul 06; 276(27):25318-23. . View in PubMed

Developmentally and regionally regulated participation of epidermal cells in the formation of collagen lamella of anuran tadpole skin Dev Growth Differ. 2000 Dec; 42(6):571-80. . View in PubMed

Kdap, a novel gene associated with the stratification of the epithelium Gene. 2000 Oct 03; 256(1-2):19-27. . View in PubMed

Expression of genes of type I and type II collagen in the formation and development of the blastema of regenerating newt limb Dev Dyn. 1999 Sep; 216(1):59-71. . View in PubMed

Cell-type specific and thyroid hormone-dependent expression of genes of alpha1(I) and alpha2(I) collagen in intestine during amphibian metamorphosis Matrix Biol. 1999 Feb; 18(1):89-103. . View in PubMed

Cloning and characterization of the full length cDNA encoding alpha2 type I collagen of bullfrog Rana catesbeiana Gene. 1997 Jul 31; 194(2):283-9. . View in PubMed

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