{"id":19,"date":"2023-09-03T16:38:02","date_gmt":"2023-09-03T16:38:02","guid":{"rendered":"https:\/\/keck.usc.edu\/medicine\/?page_id=19"},"modified":"2025-08-27T17:46:25","modified_gmt":"2025-08-27T17:46:25","slug":"research","status":"publish","type":"page","link":"https:\/\/keck.usc.edu\/medicine\/research\/","title":{"rendered":"Research"},"content":{"rendered":"\n\n\n\n\n  \n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--hero-primary horizontal-navigation\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--hero-primary\"\n    \n      >\n\n    \n  \n  <div class=\"inner-wrapper has-horizontal-nav\">\n\n          <div class=\"title-wrapper\">\n\n                  <div class=\"eyebrow-container\">\n                              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <a href=\"https:\/\/keck.usc.edu\/medicine\/\"  aria-label=\"Read more about Department of Medicine\">Department of Medicine<\/a>\n\n\n\n<\/div>\n                      <\/div>\n        \n                      \n<div class=\"f--field f--page-title has-stripe\">\n\n    \n      <h1>Research<\/h1>\n\n\n<\/div>\n        \n              <\/div>\n    \n              \n<div class=\"f--field f--link eyebrow-link\">\n\n    \n    \n  \n<a\n  class=\"link \"\n  href=\"https:\/\/www.keckmedicine.org\/conditions-and-treatments\/\"\n  target=\"_blank\"  aria-label=\"Read&#x20;more&#x20;about&#x20;Are&#x20;you&#x20;a&#x20;patient&#x3F;\">\n        Are you a patient?\n    <\/a>\n\n\n<\/div>\n    \n    \n      \n              <div class=\"horizontal-nav\">\n                      <div class=\"horizontal-menu-container\">\n              <button class=\"expand-menu\">\n                                  In This Section\n                                <svg class=\"menu\" version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" x=\"0px\"\n                  y=\"0px\" viewBox=\"0 0 35 35\" enable-background=\"new 0 0 35 35\" 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class=\"c--component c--featured-block\"\n    \n      >\n\n    \n  <div class=\"text-image-container\">\n    <div class=\"text-container\">\n\n      \n                  \n<div class=\"f--field f--section-title has-stripe\">\n\n    \n  <h2>\n          About Our Research Programs\n      <\/h2>\n\n\n<\/div>\n      \n                  \n<div class=\"f--field f--description description-medium\">\n\n    \n  <p>More than 111 Department of Medicine faculty are currently engaged in basic and\/or clinical (translational) research activities, 90 of them as principal investigators (PI). These medical research programs are supported by expenditures now exceeding $50 million annually, of which 53 percent are federally sponsored (primarily by the National Institutes of Health).<\/p>\n\n\n\n<\/div>\n      \n      \n    <\/div>\n\n          <div class=\"image-container\">\n            \n<div class=\"f--field f--image\">\n\n    \n    \n    \n    \n    \n    \n              \n      <img\n                            data-src=\"https:\/\/keck.usc.edu\/medicine\/wp-content\/uploads\/sites\/65\/2023\/09\/Home-Research-768x768.jpg\"\n          data-srcset=\"https:\/\/keck.usc.edu\/medicine\/wp-content\/uploads\/sites\/65\/2023\/09\/Home-Research-768x768.jpg 768w\"          data-sizes=\"(min-width:1024px) 50vw, (min-width:768px) 100vw, 100vw\"          class=\"lazyload\"\n        \n        alt=\"Physician looks at scan\"\n        \n                                      \/>\n\n    \n    \n  \n  \n\n<\/div>\n      <\/div>\n    \n  <\/div>\n\n\n  <\/div><\/div>\n\n\n\n\n\n\n    \n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--accordions \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--accordions\"\n    \n      >\n\n    \n      <div class=\"header-container\">\n\n                  \n<div class=\"f--field f--section-title\">\n\n    \n  <h2>\n          Prominent examples of such programmatic efforts include:\n      <\/h2>\n\n\n<\/div>\n      \n      \n    <\/div>\n  \n      <ul>\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-1-Dip5Up92fy\" aria-controls=\"section-1-1-Dip5Up92fy\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Basic\/Translational Science<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-1-Dip5Up92fy\" role=\"region\" aria-labelledby=\"heading-1-1-Dip5Up92fy\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <ul>\n<li>Center for Molecular Pathways and Drug Discovery (Lenz)<\/li>\n<li>Circulating Tumor Cell Research Core Center (Goldkorn)<\/li>\n<li>Diabetes and Obesity Research Center (Buchanan)<\/li>\n<li><a href=\"https:\/\/gehrcenter.usc.edu\/\" target=\"_blank\" rel=\"noopener\">Gehr Family Center for Implementation Science (Kaplan)<\/a><\/li>\n<li>Gehr Family Center for Rare Blood Disorders (O\u2019Connell)<\/li>\n<li><a href=\"https:\/\/hastingscenter.usc.edu\/\" target=\"_blank\" rel=\"noopener\">Hastings Center for Pulmonary Research<\/a><\/li>\n<li>Lupus Center (Stohl)<\/li>\n<li>Research Center for Cell Therapy (Chaudhary)<\/li>\n<li><a href=\"\/liver-diseases-research-center\/\" target=\"_blank\" rel=\"noopener\">Research Center for Liver Diseases <\/a><\/li>\n<li><a href=\"https:\/\/cbc.ict.usc.edu\/\" target=\"_blank\" rel=\"noopener\">USC Center for Body Computing (Saxon)<\/a><\/li>\n<li><a href=\"\/usc-ukro-kidney-research-center\/\" target=\"_blank\" rel=\"noopener\">USC\/UKRO Kidney Research Center (Hallows)<\/a><\/li>\n<\/ul>\n<div id=\"gtx-trans\" style=\"position: absolute; left: 423px; top: 358px;\">\n<div class=\"gtx-trans-icon\"><\/div>\n<\/div>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-2-Dip5Up92fy\" aria-controls=\"section-1-2-Dip5Up92fy\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Large-Scale Clinical Trials<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-2-Dip5Up92fy\" role=\"region\" aria-labelledby=\"heading-1-2-Dip5Up92fy\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <ul>\n<li><a href=\"https:\/\/aru.usc.edu\/about-aru\/\" target=\"_blank\" rel=\"noopener\">Atherosclerosis Research Unit (Hodis)<\/a><\/li>\n<li>Keck Diabetes Prevention Initiative and NIH LookAHEAD Study (Peters)<\/li>\n<li>SC CTSI and Clinical Trials Unit (Buchanan)<\/li>\n<li>USC Gestational Diabetes Study Group (Page)<\/li>\n<\/ul>\n<div id=\"gtx-trans\" style=\"position: absolute; left: 405px; top: 262px;\">\n<div class=\"gtx-trans-icon\"><\/div>\n<\/div>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n          <\/ul>\n  \n\n  <\/div><\/div>\n\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--featured-block image-left white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--featured-block\"\n    \n      >\n\n    \n  <div class=\"text-image-container\">\n    <div class=\"text-container\">\n\n      \n                  \n<div class=\"f--field f--section-title has-stripe\">\n\n    \n  <h2>\n          Clinical Research\n      <\/h2>\n\n\n<\/div>\n      \n                  \n<div class=\"f--field f--description description-medium\">\n\n    \n  <p>The Department of Medicine faculty members are principal investigators on 110 new and 344 continuing research grants in the last year.<\/p>\n<p>Many of these programs have taken advantage of the unique and diverse patient populations served by our teaching hospitals and clinics, as well as the leadership talents of our faculty.<\/p>\n\n\n\n<\/div>\n      \n      \n    <\/div>\n\n          <div class=\"image-container\">\n            \n<div class=\"f--field f--image\">\n\n    \n    \n    \n    \n    \n    \n              \n      <img\n                            data-src=\"https:\/\/keck.usc.edu\/medicine\/wp-content\/uploads\/sites\/65\/2023\/09\/Research-Clinical-768x768.jpg\"\n          data-srcset=\"https:\/\/keck.usc.edu\/medicine\/wp-content\/uploads\/sites\/65\/2023\/09\/Research-Clinical-768x768.jpg 768w\"          data-sizes=\"(min-width:1024px) 50vw, (min-width:768px) 100vw, 100vw\"          class=\"lazyload\"\n        \n        alt=\"Two doctors review research\"\n        \n                                      \/>\n\n    \n    \n  \n  \n\n<\/div>\n      <\/div>\n    \n  <\/div>\n\n\n  <\/div><\/div>\n\n\n\n\n\n\n          \n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--accordions \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--accordions\"\n    \n      >\n\n    \n      <div class=\"header-container\">\n\n                  \n<div class=\"f--field f--section-title\">\n\n    \n  <h2>\n          Large-Scale Clinical Trial Centers\n      <\/h2>\n\n\n<\/div>\n      \n      \n    <\/div>\n  \n      <ul>\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-1-qEbNpbxhJU\" aria-controls=\"section-1-1-qEbNpbxhJU\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Atherosclerosis Research Unit<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-1-qEbNpbxhJU\" role=\"region\" aria-labelledby=\"heading-1-1-qEbNpbxhJU\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>Under the leadership of Howard N. Hodis, MD, the Atherosclerosis Research Unit focuses on in vivo assessment of atherosclerosis. Using cutting-edge noninvasive technology to assess changes in intimal thickness in major arterial vessels, this Unit is conducting studies designed to assess the benefits of a wide variety of therapeutic interventions for prevention and reversal of atherosclerosis.<\/p>\n<p><a class=\"read-more\" href=\"http:\/\/aru.usc.edu\" aria-label=\"Learn More About Atherosclerosis Research Unit\">Learn more<\/a><\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-2-qEbNpbxhJU\" aria-controls=\"section-1-2-qEbNpbxhJU\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">AIDS Clinical Trials Group<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-2-qEbNpbxhJU\" role=\"region\" aria-labelledby=\"heading-1-2-qEbNpbxhJU\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>Under the direction of Fred R. Sattler, MD, the adult AIDS Clinical Trials Group (ACTG) has become one of the nation\u2019s leading centers in carrying out NIH-sponsored AIDS clinical trials in adult populations.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-3-qEbNpbxhJU\" aria-controls=\"section-1-3-qEbNpbxhJU\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Keck Diabetes Prevention Initiative<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-3-qEbNpbxhJU\" role=\"region\" aria-labelledby=\"heading-1-3-qEbNpbxhJU\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The Keck Diabetes Prevention Initiative, directed by Anne Peters, MD, is a program designed to develop treatment programs for the epidemic of obesity and type II diabetes occurring in the medically underserved populations of Los Angeles. As part of this program, the NIH-sponsored LookAHEAD Study focuses on the benefits of weight loss and exercise in reducing the risk of cardiovascular disease in a select type 2 diabetes population located in East Los Angeles.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-4-qEbNpbxhJU\" aria-controls=\"section-1-4-qEbNpbxhJU\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Southern California Clinical and Translational Science Institute (SC CTSI)<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-4-qEbNpbxhJU\" role=\"region\" aria-labelledby=\"heading-1-4-qEbNpbxhJU\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>In recognition of the importance of translational research to the improvement of medical care and health, the National Institutes of Health (NIH) established the Clinical and Translational Science Awards (CTSA) program, which provides grants to leading universities to provide resources to support clinical and translational research and training. Dr. Thomas Buchanan led a team of Keck School of Medicine of USC faculty members who competed successfully for a CTSA in 2010 and renewed funding in 2016, for a total of $98 million. The funds support the Southern California Clinical and Translational Science Institute (SC CTSI), based at the Keck School and Children\u2019s Hospital Los Angeles, which has partnerde with the Los Angeles County Department of Health Services and more than 60 health-oriented community organizations. The SC CTSI provides a broad range of services and support to promote clinical and community trials, develop new methods to enhance the efficiency and effectiveness of clinical research, provide training in clinical and translational research, and disseminate research findings to improve clinical care and community health.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-5-qEbNpbxhJU\" aria-controls=\"section-1-5-qEbNpbxhJU\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">USC Gestational Diabetes (USC GDM) Study Group<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-5-qEbNpbxhJU\" role=\"region\" aria-labelledby=\"heading-1-5-qEbNpbxhJU\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The USC Gestational Diabetes (USC GDM) Study Group, which has been operating for nearly 30 years, has been the home of one of the world\u2019s leading programs on the causes, treatment and prevention of gestational diabetes mellitus and type 2 diabetes mellitus in Hispanic Americans. In a series of four large studies involving more than 1,500 individuals who were diagnosed with gestational diabetes during pregnancy, the USC GDM Study Group worked out the risk factors and mechanisms for development of gestational and type 2 diabetes, as well as effective approaches to diabetes prevention. In related studies, the group identified a novel approach to the clinical care of women with gestational diabetes, using measurements of fetal growth by ultrasound to complement and in many cases supplant difficult and labor-intensive glucose self-monitoring as the primary approach to guide treatment. Today, the work of the USC GDM Study Group forms the basis for many components of clinical care of women with gestational diabetes.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n          <\/ul>\n  \n\n  <\/div><\/div>\n\n\n\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--featured-block white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--featured-block\"\n    \n      >\n\n    \n  <div class=\"text-image-container\">\n    <div class=\"text-container\">\n\n      \n                  \n<div class=\"f--field f--section-title has-stripe\">\n\n    \n  <h2>\n          Basic Science Research\n      <\/h2>\n\n\n<\/div>\n      \n                  \n<div class=\"f--field f--description description-medium\">\n\n    \n  <p>Basic sciences researchers represent multiple divisions and illustrate our missions of building an outstanding research workforce for the future.<\/p>\n<p>Department of Medicine faculty members have continued to garner outstanding NIH grant support at a time of intense competition for extramural funding.<\/p>\n\n\n\n<\/div>\n      \n      \n    <\/div>\n\n          <div class=\"image-container\">\n            \n<div class=\"f--field f--image\">\n\n    \n    \n    \n    \n    \n    \n              \n      <img\n                            data-src=\"https:\/\/keck.usc.edu\/medicine\/wp-content\/uploads\/sites\/65\/2023\/09\/Research-BasicSci-768x768.jpg\"\n          data-srcset=\"https:\/\/keck.usc.edu\/medicine\/wp-content\/uploads\/sites\/65\/2023\/09\/Research-BasicSci-768x768.jpg 768w\"          data-sizes=\"(min-width:1024px) 50vw, (min-width:768px) 100vw, 100vw\"          class=\"lazyload\"\n        \n        alt=\"Researcher looks through microscope\"\n        \n                                      \/>\n\n    \n    \n  \n  \n\n<\/div>\n      <\/div>\n    \n  <\/div>\n\n\n  <\/div><\/div>\n\n\n\n\n\n\n                        \n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--accordions \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--accordions\"\n    \n      >\n\n    \n      <div class=\"header-container\">\n\n                  \n<div class=\"f--field f--section-title\">\n\n    \n  <h2>\n          Research Areas\n      <\/h2>\n\n\n<\/div>\n      \n      \n    <\/div>\n  \n      <ul>\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-1-d90hTlyNl7\" aria-controls=\"section-1-1-d90hTlyNl7\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Cardiovascular Devices Program<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-1-d90hTlyNl7\" role=\"region\" aria-labelledby=\"heading-1-1-d90hTlyNl7\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The Cardiovascular Devices Program, led by Leslie Saxon, MD, is dedicated to the development of innovative uses of new implantable device technologies. Such new technologies will allow the introduction of major preventive and\/or critical therapeutic measures at the earliest stages of disease development.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-2-d90hTlyNl7\" aria-controls=\"section-1-2-d90hTlyNl7\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Center for Molecular Pathways and Drug Discovery<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-2-d90hTlyNl7\" role=\"region\" aria-labelledby=\"heading-1-2-d90hTlyNl7\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The Center for Molecular Pathways and Drug Discovery, focuses on accelerating the pace of drug discovery and the development of less toxic and more effective therapies for the treatment of cancer and other diseases. Heinz-Josef Lenz, MD, co-directs the center with Michael Kahn, PhD from the USC School of Pharmacy.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-3-d90hTlyNl7\" aria-controls=\"section-1-3-d90hTlyNl7\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Circulating Tumor Cell Research Center<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-3-d90hTlyNl7\" role=\"region\" aria-labelledby=\"heading-1-3-d90hTlyNl7\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The Circulating Tumor Cell Research Center, founded by Amir Goldkorn, MD, is a state-of-the-art, multi-platform facility for the capture and analysis of peripheral blood circulating tumor cells.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-4-d90hTlyNl7\" aria-controls=\"section-1-4-d90hTlyNl7\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">The Diabetes and Obesity Research Center<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-4-d90hTlyNl7\" role=\"region\" aria-labelledby=\"heading-1-4-d90hTlyNl7\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The Diabetes and Obesity Research Center was established to investigate the origin, prevention and treatment of diabetes and associated conditions (including obesity, hyperlipidemia, hypertension and atherosclerosis). Thomas A. Buchanan, MD, shares the leadership role in developing this important multidisciplinary research program with Michael Goran, PhD, from the Department of Population and Public Health Sciences.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-5-d90hTlyNl7\" aria-controls=\"section-1-5-d90hTlyNl7\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">The Gehr Family Center for Implementation Health Systems Science<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-5-d90hTlyNl7\" role=\"region\" aria-labelledby=\"heading-1-5-d90hTlyNl7\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The Gehr Family Center for Implementation Science, established by David Goldstein, MD, and led by Michael Hochman, MD, creates innovative collaborations to develop and promote sustainable, efficient, clinical quality improvement strategies. Working with partners such as Los Angeles General Medical Center, the Center identities and integrates best practices into routine health care for patients.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-6-d90hTlyNl7\" aria-controls=\"section-1-6-d90hTlyNl7\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">The Gehr Family Center for Rare Blood Disorders<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-6-d90hTlyNl7\" role=\"region\" aria-labelledby=\"heading-1-6-d90hTlyNl7\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The Gehr Family Center for Rare Blood Disorders, led by Casey O\u2019Connell, MD, conducts translational research into blood diseases such as myelodysplastic syndromes, which can lead to leukemia and AML, the most common adult acute leukemia.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-7-d90hTlyNl7\" aria-controls=\"section-1-7-d90hTlyNl7\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Hastings Center for Pulmonary Research (HCPR)<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-7-d90hTlyNl7\" role=\"region\" aria-labelledby=\"heading-1-7-d90hTlyNl7\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The Hastings Center for Pulmonary Research (HCPR), under the direction of Zea Borok, MD, strives to be a leader in lung biology and disease research. HCPR scientists interact with clinicians to translate their research findings into clinical applications.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-8-d90hTlyNl7\" aria-controls=\"section-1-8-d90hTlyNl7\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">The Lupus Center<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-8-d90hTlyNl7\" role=\"region\" aria-labelledby=\"heading-1-8-d90hTlyNl7\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The Lupus Center, led by William Stohl, PhD, MD, uses information gained by laboratory bench research to serve as the basis for the development of prototype treatment strategies for a wide variety of autoimmune diseases.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-9-d90hTlyNl7\" aria-controls=\"section-1-9-d90hTlyNl7\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Research Center for Cell Therapy<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-9-d90hTlyNl7\" role=\"region\" aria-labelledby=\"heading-1-9-d90hTlyNl7\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The Research Center for Cell Therapy, led by Preet Chaudhary, MD, PhD, will strengthen and expand the existing capabilities of cell based therapies by bringing together basic, translational and clinical investigators working on developing novel cell based therapies for the treatment of hard-to-treat diseases, such as immunodeficiency disorders, autoimmune disorders, genetic diseases and in-born errors of metabolism.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-10-d90hTlyNl7\" aria-controls=\"section-1-10-d90hTlyNl7\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">Research Center for Liver Diseases<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-10-d90hTlyNl7\" role=\"region\" aria-labelledby=\"heading-1-10-d90hTlyNl7\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The NIH-sponsored Research Center for Liver Diseases and core laboratories (Molecular Biology, Cell Culture and Organelle), led by Neil K. Kaplowitz, MD, is one of only four such programs in the nation. In addition to basic and translational research programs in liver disease, this center provides a major institutional resource for multidisciplinary and interdepartmental investigations, educational seminars and start-up grant funding opportunities.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-11-d90hTlyNl7\" aria-controls=\"section-1-11-d90hTlyNl7\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">USC Center for Body Computing<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-11-d90hTlyNl7\" role=\"region\" aria-labelledby=\"heading-1-11-d90hTlyNl7\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The USC Center for Body Computing, led by Leslie Saxon, MD, is dedicated to the development of innovative uses of new implantable device technologies. Such new technologies will allow the introduction of major preventive and\/or critical therapeutic measures at the earliest stages of disease development.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n              <li>\n          <button type=\"button\" class=\"accordion-trigger \" id=\"heading-1-12-d90hTlyNl7\" aria-controls=\"section-1-12-d90hTlyNl7\" aria-expanded=\"false\" aria-disabled=\"false\">\n                          <span class=\"item-title\">USC\/UKRO Kidney Research Center<\/span>\n            \n                      <\/button>\n\n          <div id=\"section-1-12-d90hTlyNl7\" role=\"region\" aria-labelledby=\"heading-1-12-d90hTlyNl7\" class=\"accordion-panel\">\n\n                            \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>The USC\/UKRO Kidney Research Center, founded by Vito Campese, MD, and led by Kenneth Hallows, MD, PhD, is dedicated to the belief that collaboration among scientists is key to understanding and eliminating chronic kidney disease (CKD). The center focuses on the research of the mechanisms of hypertension, acute kidney injury, acid regulation and its role in CKD, polycystic kidney disease and metabolomics biomarkers, and kidney cancer.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n            \n                      <\/div>\n        <\/li>\n\n          <\/ul>\n  \n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":true,"footnotes":""},"class_list":["post-19","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Research - Department of Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/keck.usc.edu\/medicine\/research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research\" \/>\n<meta property=\"og:url\" content=\"https:\/\/keck.usc.edu\/medicine\/research\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Medicine\" \/>\n<meta property=\"article:modified_time\" content=\"2025-08-27T17:46:25+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/keck.usc.edu\\\/medicine\\\/research\\\/\",\"url\":\"https:\\\/\\\/keck.usc.edu\\\/medicine\\\/research\\\/\",\"name\":\"Research - 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