John M. Ringman

John M. Ringman

Professor of Clinical Neurology
CHP 210 1540 Alcazar St. Health Sciences Campus Los Angeles


Retinotopic degeneration of the retina and optic tracts in autosomal dominant Alzheimer's disease Alzheimers Dement. 2023 Apr 27. . View in PubMed

Vessel Density Mapping of Cerebral Small Vessels on 3D High Resolution Black Blood MRI bioRxiv. 2023 Mar 21. . View in PubMed

Decreased functional connectivity is associated with increased levels of Cerebral Spinal Fluid soluble-PDGFRß, a marker of blood brain barrier breakdown, in older adults Res Sq. 2023 Mar 07. . View in PubMed

First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer's disease: the Dominantly Inherited Alzheimer's Network Study J Neurol Neurosurg Psychiatry. 2023 05; 94(5):403-405. . View in PubMed

Retinal pathological features and proteome signatures of Alzheimer's disease Acta Neuropathol. 2023 04; 145(4):409-438. . View in PubMed

Pattern and implications of neurological examination findings in autosomal dominant Alzheimer disease Alzheimers Dement. 2023 02; 19(2):632-645. . View in PubMed

Characterization of spastic paraplegia in a family with a novel PSEN1 mutation Brain Commun. 2023; 5(2):fcad030. . View in PubMed

The association between white matter hyperintensities and amyloid and tau deposition Neuroimage Clin. 2023; 38:103383. . View in PubMed

Amyloid-Related Imaging Abnormalities in the DIAN-TU-001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease Ann Neurol. 2022 11; 92(5):729-744. . View in PubMed

Different rates of cognitive decline in autosomal dominant and late-onset Alzheimer disease Alzheimers Dement. 2022 10; 18(10):1754-1764. . View in PubMed

Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer's disease Neurobiol Aging. 2022 04; 112:39-54. . View in PubMed

Front Aging Neurosci. 2022; 14:883131. . View in PubMed

Enhanced Association of Tau Pathology and Cognitive Impairment in Mild Cognitive Impairment Subjects with Behavior Symptoms J Alzheimers Dis. 2022; 87(2):557-568. . View in PubMed

Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology Brain. 2022 10 21; 145(10):3594-3607. . View in PubMed

Attitudes about involvement in hypothetical clinical trial protocols in Mexican and Mexican-American at risk for autosomal dominant Alzheimer's disease Alzheimers Res Ther. 2022 11 15; 14(1):173. . View in PubMed

Cerebral Amyloid Angiopathy-related Inflammation Presenting With a Cystic Lesion in Young-onset Alzheimer Disease Alzheimer Dis Assoc Disord. 2021 Jul-Sep 01; 35(3):265-268. . View in PubMed

Comparing amyloid-ß plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease Acta Neuropathol. 2021 10; 142(4):689-706. . View in PubMed

Comparison of CSF biomarkers in Down syndrome and autosomal dominant Alzheimer's disease: a cross-sectional study Lancet Neurol. 2021 08; 20(8):615-626. . View in PubMed

Past, present and future role of retinal imaging in neurodegenerative disease Prog Retin Eye Res. 2021 07; 83:100938. . View in PubMed

"My backpack is so heavy": Experiences of Latino caregivers of family with early-onset Alzheimer's J Am Geriatr Soc. 2021 06; 69(6):1539-1547. . View in PubMed

MarkVCID cerebral small vessel consortium: IEnrollment, clinical, fluid protocols. Alzheimers Dement. 2021 04; 17(4):704-715. . View in PubMed

Volumetric distribution of perivascular space in relation to mild cognitive impairment Neurobiol Aging. 2021 03; 99:28-43. . View in PubMed

Cerebroarterial pulsatility and resistivity indices are associated with cognitive impairment and white matter hyperintensity in elderly subjects: A phase-contrast MRI study J Cereb Blood Flow Metab. 2021 03; 41(3):670-683. . View in PubMed

Reaction time and response inhibition in autosomal dominant Alzheimer's disease Brain Cogn. 2021 02; 147:105656. . View in PubMed

Abnormal retinal capillary blood flow in autosomal dominant Alzheimer's disease Alzheimers Dement (Amst). 2021; 13(1):e12162. . View in PubMed

Evaluation of Cerebral Blood Flow Measured by 3D PCASL as Biomarker of Vascular Cognitive Impairment and Dementia (VCID) in a Cohort of Elderly Latinx Subjects at Risk of Small Vessel Disease Front Neurosci. 2021; 15:627627. . View in PubMed

Pattern and degree of individual brain atrophy predicts dementia onset in dominantly inherited Alzheimer's disease Alzheimers Dement (Amst). 2021; 13(1):e12197. . View in PubMed

Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease Neurology. 2021 03 23; 96(12):e1632-e1645. . View in PubMed

A probabilistic atlas of locus coeruleus pathways to transentorhinal cortex for connectome imaging in Alzheimer's disease Neuroimage. 2020 12; 223:117301. . View in PubMed

Autosomal dominant early onset Alzheimer's disease in the Mexican state of Jalisco: High frequency of the mutation PSEN1 c1292C>A and phenotypic profile of patients. Am J Med Genet C Semin Med Genet. 2020 12; 184(4):1023-1029. . View in PubMed

Emotional detachment, gait ataxia, and cerebellar dysconnectivity associated with compound heterozygous mutations in the SPG7 gene Neurocase. 2020 10; 26(5):299-304. . View in PubMed

A novel sensitive assay for detection of a biomarker of pericyte injury in cerebrospinal fluid Alzheimers Dement. 2020 06; 16(6):821-830. . View in PubMed

APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline Nature. 2020 05; 581(7806):71-76. . View in PubMed

Lower retinal capillary density in minimal cognitive impairment among older Latinx adults Alzheimers Dement (Amst). 2020; 12(1):e12071. . View in PubMed

Comparison Between Blood-Brain Barrier Water Exchange Rate and Permeability to Gadolinium-Based Contrast Agent in an Elderly Cohort Front Neurosci. 2020; 14:571480. . View in PubMed

Probing Estrogen Sulfotransferase-Mediated Inflammation with [11C]-PiB in the Living Human Brain J Alzheimers Dis. 2020; 73(3):1023-1033. . View in PubMed

Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies Alzheimers Dement (Amst). 2019 Dec; 11:180-190. . View in PubMed

Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders Alzheimer Dis Assoc Disord. 2019 Oct-Dec; 33(4):327-330. . View in PubMed

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing Nat Genet. 2019 Sep; 51(9):1423-1424. . View in PubMed

1H MRS spectroscopy in preclinical autosomal dominant Alzheimer disease Brain Imaging Behav. 2019 Aug; 13(4):925-932. . View in PubMed

Treatment Options for Agitation in Dementia Curr Treat Options Neurol. 2019 Jun 24; 21(7):30. . View in PubMed

A mixed-methods study of cultural beliefs about dementia and genetic testing among Mexicans and Mexican-Americans at-risk for autosomal dominant Alzheimer's disease J Genet Couns. 2019 10; 28(5):921-932. . View in PubMed

Historical Migration revealed through a Case of Autosomal Dominant Alzheimer's Disease P R Health Sci J. 2019 09; 38(3):144-147. . View in PubMed

Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease Alzheimers Dement. 2019 05; 15(5):655-665. . View in PubMed

Mapping water exchange across the blood-brain barrier using 3D diffusion-prepared arterial spin labeled perfusion MRI Magn Reson Med. 2019 05; 81(5):3065-3079. . View in PubMed

Seizures as an early symptom of autosomal dominant Alzheimer's disease Neurobiol Aging. 2019 04; 76:18-23. . View in PubMed

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing Nat Genet. 2019 03; 51(3):414-430. . View in PubMed

Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction Nat Med. 2019 02; 25(2):270-276. . View in PubMed

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease Nat Med. 2019 02; 25(2):277-283. . View in PubMed

Cognitive symptoms of Alzheimer's disease: clinical management and prevention BMJ. 2019 12 06; 367:l6217. . View in PubMed

Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease Brain. 2019 05 01; 142(5):1429-1440. . View in PubMed

Homozygosity for the A431E mutation in PSEN1 presenting with a relatively aggressive phenotype Neurosci Lett. 2019 04 23; 699:195-198. . View in PubMed

CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline EMBO Mol Med. 2018 12; 10(12). . View in PubMed

Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease Alzheimers Dement. 2018 11; 14(11):1427-1437. . View in PubMed

Impairment of memory generalization in preclinical autosomal dominant Alzheimer's disease mutation carriers Neurobiol Aging. 2018 05; 65:149-157. . View in PubMed

Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial magnetic resonance imaging study Alzheimers Dement. 2018 01; 14(1):43-53. . View in PubMed

Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing Brain. 2018 05 01; 141(5):1486-1500. . View in PubMed

A probabilistic atlas of human brainstem pathways based on connectome imaging data Neuroimage. 2018 04 01; 169:227-239. . View in PubMed

Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease Neurology. 2018 10 02; 91(14):e1295-e1306. . View in PubMed

Utility of perfusion PET measures to assess neuronal injury in Alzheimer's disease Alzheimers Dement (Amst). 2018; 10:669-677. . View in PubMed

Regional association of pCASL-MRI with FDG-PET and PiB-PET in people at risk for autosomal dominant Alzheimer's disease Neuroimage Clin. 2018; 17:751-760. . View in PubMed

White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease PLoS One. 2018; 13(5):e0195838. . View in PubMed

Attitudes toward clinical trials across the Alzheimer's disease spectrum Alzheimers Res Ther. 2017 Oct 04; 9(1):81. . View in PubMed

A novel PSEN1 (S230N) mutation causing early-onset Alzheimer's Disease associated with prosopagnosia, hoarding, and Parkinsonism Neurosci Lett. 2017 Sep 14; 657:11-15. . View in PubMed

Patient and caregiver reactions to clinical amyloid imaging Alzheimers Dement. 2017 Aug; 13(8):924-932. . View in PubMed

Update on Alzheimer's and the Dementias: Introduction Neurol Clin. 2017 May; 35(2):171-174. . View in PubMed

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease Nat Genet. 2017 09; 49(9):1373-1384. . View in PubMed

Alzheimer and the Dementias Neurol Clin. 2017 05; 35(2):ix-x. . View in PubMed

Two Novel Mutations in the First Transmembrane Domain of Presenilin1 Cause Young-Onset Alzheimer's Disease J Alzheimers Dis. 2017; 58(4):1035-1041. . View in PubMed

A comparison of theoretical and statistically derived indices for predicting cognitive decline Alzheimers Dement (Amst). 2017; 6:171-181. . View in PubMed

Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease Sci Rep. 2017 04 27; 7(1):1225. . View in PubMed

Neuropsychological Profiles Differentiate Alzheimer Disease from Subcortical Ischemic Vascular Dementia in an Autopsy-Defined Cohort Dement Geriatr Cogn Disord. 2017; 44(1-2):1-11. . View in PubMed

Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS) Lancet Neurol. 2016 Dec; 15(13):1317-1325. . View in PubMed

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network Ann Neurol. 2016 Jun; 79(6):929-39. . View in PubMed

Improvement of Dream Enactment Behavior Associated With Levetiracetam Treatment in Dementia With Lewy Bodies Alzheimer Dis Assoc Disord. 2016 Apr-Jun; 30(2):175-7. . View in PubMed

Neuropathology of Autosomal Dominant Alzheimer Disease in the National Alzheimer Coordinating Center Database J Neuropathol Exp Neurol. 2016 Mar; 75(3):284-90. . View in PubMed

Widespread white matter and conduction defects in PSEN1-related spastic paraparesis Neurobiol Aging. 2016 11; 47:201-209. . View in PubMed

BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease Brain. 2016 10; 139(Pt 10):2766-2777. . View in PubMed

Are Late-Onset Autosomal Dominant and Sporadic Alzheimer Disease "Separate but Equal"? JAMA Neurol. 2016 09 01; 73(9):1060-1.. View in PubMed

Assessing intracranial vascular compliance using dynamic arterial spin labeling Neuroimage. 2016 Jan 01; 124(Pt A):433-441. . View in PubMed

Critical review of the Appropriate Use Criteria for amyloid imaging: Effect on diagnosis and patient care Alzheimers Dement (Amst). 2016; 5:15-22. . View in PubMed

Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group PLoS One. 2016; 11(9):e0163669. . View in PubMed

Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group PLoS One. 2016; 11(3):e0152082. . View in PubMed

Impairments in the Face-Processing Network in Developmental Prosopagnosia and Semantic Dementia Cogn Behav Neurol. 2015 Dec; 28(4):188-97. . View in PubMed

Daily Activity Abilities in MCI, Alzheimer's Disease, and Healthy Controls GeroPsych (Bern). 2015 Dec; 28(4):191-200. . View in PubMed

Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease Neurology. 2015 Sep 01; 85(9):790-8. . View in PubMed

Donepezil treatment in ethnically diverse patients with Alzheimer disease Am J Geriatr Psychiatry. 2015 Apr; 23(4):384-390. . View in PubMed

Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network Brain. 2015 Apr; 138(Pt 4):1036-45. . View in PubMed

A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy JAMA Neurol. 2015 Apr; 72(4):414-22. . View in PubMed

Factors associated with the onset and persistence of post-lumbar puncture headache JAMA Neurol. 2015 Mar; 72(3):325-32. . View in PubMed

Rarity of the Alzheimer disease-protective APP A673T variant in the United States JAMA Neurol. 2015 Feb; 72(2):209-16. . View in PubMed

A survey of attitudes toward clinical trials and genetic disclosure in autosomal dominant Alzheimer's disease Alzheimers Res Ther. 2015; 7(1):50. . View in PubMed

Use of the MoCA in Detecting Early Alzheimer's Disease in a Spanish-Speaking Population with Varied Levels of Education Dement Geriatr Cogn Dis Extra. 2015 Jan-Apr; 5(1):85-95. . View in PubMed

Conceptualization and assessment of vulnerability in a complex international Alzheimer's research study Am J Bioeth. 2015; 15(4):87-9. . View in PubMed

JAMA Neurol. 2014 Dec; 71(12):1481-9. . View in PubMed

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study JAMA Neurol. 2014 Nov; 71(11):1394-404. . View in PubMed

Genetic heterogeneity in Alzheimer disease and implications for treatment strategies Curr Neurol Neurosci Rep. 2014 Nov; 14(11):499. . View in PubMed

Functional connectivity in autosomal dominant and late-onset Alzheimer disease JAMA Neurol. 2014 Sep; 71(9):1111-22. . View in PubMed

Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis Neurology. 2014 Jul 15; 83(3):253-60. . View in PubMed

Clinical predictors of severe cerebral amyloid angiopathy and influence of APOE genotype in persons with pathologically verified Alzheimer disease JAMA Neurol. 2014 Jul 01; 71(7):878-83. . View in PubMed

Younger age of dementia diagnosis in a Hispanic population in southern California Int J Geriatr Psychiatry. 2014 Jun; 29(6):586-93. . View in PubMed

Age effects on cortical thickness in cognitively normal elderly individuals Dement Geriatr Cogn Dis Extra. 2014 May; 4(2):221-7. . View in PubMed

Reliability of two-dimensional and three-dimensional pseudo-continuous arterial spin labeling perfusion MRI in elderly populations: comparison with 15O-water positron emission tomography J Magn Reson Imaging. 2014 Apr; 39(4):931-9. . View in PubMed

The "Alzheimer's type" profile of semantic clustering in amnestic mild cognitive impairment J Int Neuropsychol Soc. 2014 Apr; 20(4):402-12. . View in PubMed

Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease Sci Transl Med. 2014 Mar 05; 6(226):226ra30. . View in PubMed

A novel PSEN1 mutation (I238M) associated with early-onset Alzheimer's disease in an African-American woman J Alzheimers Dis. 2014; 40(2):271-5. . View in PubMed

Neuropathologic correlates of trial-related instruments for Alzheimer's disease Am J Neurodegener Dis. 2014; 3(1):45-9. . View in PubMed

Memory performance and fMRI signal in presymptomatic familial Alzheimer's disease Hum Brain Mapp. 2013 Dec; 34(12):3308-19. . View in PubMed

Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):E4502-9. . View in PubMed

Relation between variants in the neurotrophin receptor gene, NTRK3, and white matter integrity in healthy young adults Neuroimage. 2013 Nov 15; 82:146-53. . View in PubMed

The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study Neurology. 2013 Oct 15; 81(16):1425-33. . View in PubMed

The impact of the availability of prevention studies on the desire to undergo predictive testing in persons at risk for autosomal dominant Alzheimer's disease Contemp Clin Trials. 2013 Sep; 36(1):256-62. . View in PubMed

Impaired default network functional connectivity in autosomal dominant Alzheimer disease Neurology. 2013 Aug 20; 81(8):736-44. . View in PubMed

Similar verbal fluency patterns in amnestic mild cognitive impairment and Alzheimer's disease Arch Clin Neuropsychol. 2013 Aug; 28(5):400-10. . View in PubMed

Complexity and synchronicity of resting state blood oxygenation level-dependent (BOLD) functional MRI in normal aging and cognitive decline J Magn Reson Imaging. 2013 Jul; 38(1):36-45. . View in PubMed

New genes and new insights from old genes: update on Alzheimer disease Continuum (Minneap Minn). 2013 Apr; 19(2 Dementia):358-71. . View in PubMed

Effects of intensive cognitive-behavioral therapy on cingulate neurochemistry in obsessive-compulsive disorder J Psychiatr Res. 2013 Apr; 47(4):494-504. . View in PubMed

Regional brain volume differences in symptomatic and presymptomatic carriers of familial Alzheimer's disease mutations J Neurol Neurosurg Psychiatry. 2013 Feb; 84(2):154-62. . View in PubMed

Estimating sample sizes for predementia Alzheimer's trials based on the Alzheimer's Disease Neuroimaging Initiative Neurobiol Aging. 2013 Jan; 34(1):62-72. . View in PubMed

1a,25-dihydroxyvitamin D3 and resolvin D1 retune the balance between amyloid-ß phagocytosis and inflammation in Alzheimer's disease patients J Alzheimers Dis. 2013; 34(1):155-70. . View in PubMed

Agitation and psychosis associated with dementia with lewy bodies exacerbated by modafinil use Am J Alzheimers Dis Other Demen. 2012 Nov; 27(7):468-73. . View in PubMed

Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network Clin Investig (Lond). 2012 Oct 01; 2(10):975-984. . View in PubMed

Clinical and biomarker changes in dominantly inherited Alzheimer's disease N Engl J Med. 2012 Aug 30; 367(9):795-804. . View in PubMed

Evidence for a role of the rare pA152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet. 2012 Aug 01; 21(15):3500-12. . View in PubMed

Novel late-onset Alzheimer disease loci variants associate with brain gene expression Neurology. 2012 Jul 17; 79(3):221-8. . View in PubMed

The exception makes the rule: not all Aß plaques are created equal Neurology. 2012 Jul 17; 79(3):206-7. . View in PubMed

Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures Arch Neurol. 2012 Jul; 69(7):836-41. . View in PubMed

Plasma signaling proteins in persons at genetic risk for Alzheimer disease: influence of APOE genotype Arch Neurol. 2012 Jun; 69(6):757-64. . View in PubMed

Relationship of a variant in the NTRK1 gene to white matter microstructure in young adults J Neurosci. 2012 Apr 25; 32(17):5964-72. . View in PubMed

Increased fMRI signal with age in familial Alzheimer's disease mutation carriersNeurobiol Aging. 2012 Feb; 33(2):424. e11-21. . View in PubMed

Comparison of clinical characteristics between familial and non-familial early onset Alzheimer's disease J Neurol. 2012 10; 259(10):2182-8. . View in PubMed

Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study Alzheimers Res Ther. 2012; 4(5):43. . View in PubMed

Plasma methionine sulfoxide in persons with familial Alzheimer's disease mutations Dement Geriatr Cogn Disord. 2012; 33(4):219-25. . View in PubMed

Proteomic changes in cerebrospinal fluid of presymptomatic and affected persons carrying familial Alzheimer disease mutations Arch Neurol. 2012 Jan; 69(1):96-104. . View in PubMed

Cerebrospinal fluid biomarkers and proximity to diagnosis in preclinical familial Alzheimer's disease Dement Geriatr Cogn Disord. 2012; 33(1):1-5. . View in PubMed

Conformation-dependent oligomers in cerebrospinal fluid of presymptomatic familial Alzheimer's disease mutation carriers Dement Geriatr Cogn Dis Extra. 2012 Jan; 2(1):652-7. . View in PubMed

Should persons with autosomal dominant AD be included in clinical trials? Alzheimers Res Ther. 2011 May 23; 3(3):18.. View in PubMed

Common Alzheimer's disease risk variant within the CLU gene affects white matter microstructure in young adults J Neurosci. 2011 May 04; 31(18):6764-70. . View in PubMed

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease Nat Genet. 2011 May; 43(5):436-41. . View in PubMed

Effects of risk genes on BOLD activation in presymptomatic carriers of familial Alzheimer's disease mutations during a novelty encoding task Cereb Cortex. 2011 Apr; 21(4):877-83. . View in PubMed

Neuroimaging measures as endophenotypes in Alzheimer's disease Int J Alzheimers Dis. 2011 Mar 31; 2011:490140. . View in PubMed

Setting the stage for prevention of familial Alzheimer's disease Lancet Neurol. 2011 Mar; 10(3):200-1. . View in PubMed

Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer's disease due to a novel PSEN1 mutation Neurosci Lett. 2011 Jan 10; 487(3):287-92. . View in PubMed

Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease Alzheimers Res Ther. 2011 Jan 06; 3(1):1. . View in PubMed

Cortical and hippocampal atrophy in patients with autosomal dominant familial Alzheimer's disease Dement Geriatr Cogn Disord. 2011; 32(2):118-25. . View in PubMed

An update on the diagnosis and management of dementing conditions Rev Neurol Dis. 2011; 8(3-4):e68-87. . View in PubMed

Propositional density and apolipoprotein E genotype among persons at risk for familial Alzheimer's disease Dement Geriatr Cogn Disord. 2011; 32(3):188-92. . View in PubMed

The use of profanity during letter fluency tasks in frontotemporal dementia and Alzheimer disease Cogn Behav Neurol. 2010 Sep; 23(3):159-64. . View in PubMed

Insensitivity of visual assessment of hippocampal atrophy in familial Alzheimer's disease J Neurol. 2010 May; 257(5):839-42. . View in PubMed

Distinct cerebrospinal fluid amyloid beta peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease Mol Neurodegener. 2010 Jan 14; 5:2. . View in PubMed

Mary SEaston Center of Alzheimer's Disease Research at UCLA: advancing the therapeutic imperative. J Alzheimers Dis. 2010; 19(2):375-88. . View in PubMed

Current concepts of mild cognitive impairment and their applicability to persons at-risk for familial Alzheimer's disease Curr Alzheimer Res. 2009 Aug; 6(4):341-6. . View in PubMed

Reduction of SorLA/LR11, a sorting protein limiting beta-amyloid production, in Alzheimer disease cerebrospinal fluid Arch Neurol. 2009 Apr; 66(4):448-57. . View in PubMed

Commentary on "a roadmap for the prevention of dementia II: Leon Thal Symposium 2008" Prevention trials in persons at risk for dominantly inherited Alzheimer's disease: opportunities and challenges. Alzheimers Dement. 2009 Mar; 5(2):166-71. . View in PubMed

Diagnosing depression in Alzheimer disease with the national institute of mental health provisional criteria Am J Geriatr Psychiatry. 2008 Jun; 16(6):469-77. . View in PubMed

Myopathy associated with chronic orlistat consumption: a case report Neuromuscul Disord. 2008 May; 18(5):410-2. . View in PubMed

Mosaicism for trisomy 21 in a patient with young-onset dementia: a case report and brief literature review Arch Neurol. 2008 Mar; 65(3):412-5. . View in PubMed

Increased prevalence of significant recurrent headache in preclinical familial Alzheimer's disease mutation carriers Dement Geriatr Cogn Disord. 2008; 25(4):380-4. . View in PubMed

Children of persons with Alzheimer disease: what does the future hold? Alzheimer Dis Assoc Disord. 2008 Jan-Mar; 22(1):6-20.. View in PubMed

The Huntington disease of woody guthrie: another man done gone Cogn Behav Neurol. 2007 Dec; 20(4):238-43. . View in PubMed

Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin Proc Natl Acad Sci U S A. 2007 Jul 31; 104(31):12849-54. . View in PubMed

Diffusion tensor imaging in preclinical and presymptomatic carriers of familial Alzheimer's disease mutations Brain. 2007 Jul; 130(Pt 7):1767-76. . View in PubMed

An experimental approach to detecting dementia in Down syndrome: a paradigm for Alzheimer's disease Brain Cogn. 2007 Jun; 64(1):92-103. . View in PubMed

Performance on MMSE sub-items and education level in presenilin-1 mutation carriers without dementia Int Psychogeriatr. 2007 Apr; 19(2):323-32. . View in PubMed

Serendipitous improvement in the Yips associated with memantine use Mov Disord. 2007 Mar 15; 22(4):598-9. . View in PubMed

Visualizing language deterioration in progressive aphasias Neurology. 2006 Nov 28; 67(10):1738-9. . View in PubMed

Donepezil improves cognitive function and reduces decline in activities of daily living in people with severe Alzheimer's disease Evid Based Ment Health. 2006 Nov; 9(4):104. . View in PubMed

The A431E mutation in PSEN1 causing familial Alzheimer's disease originating in Jalisco State, Mexico: an additional fifteen families Neurogenetics. 2006 Nov; 7(4):277-9. . View in PubMed

The Thr354Ile substitution in PSEN1:: disease-causing mutation or polymorphism? Neurology. 2006 Jun 27; 66(12):1955-6.. View in PubMed

Family history of dementia in early-onset versus very late-onset Alzheimer's disease Int J Geriatr Psychiatry. 2006 Jun; 21(6):597-8. . View in PubMed

Current and emerging pharmacological treatment options for dementia Behav Neurol. 2006; 17(1):5-16. . View in PubMed

What the study of persons at risk for familial Alzheimer's disease can tell us about the earliest stages of the disorder: a review J Geriatr Psychiatry Neurol. 2005 Dec; 18(4):228-33. . View in PubMed

Earlier Alzheimer onset in Latino persons: ethnic difference vs selection bias Arch Neurol. 2005 Nov; 62(11):1786-7. . View in PubMed

Carbonic anhydrase inhibitors and amobarbital resistance Epilepsia. 2005 Aug; 46(8):1333. . View in PubMed

Ineffective phagocytosis of amyloid-beta by macrophages of Alzheimer's disease patients J Alzheimers Dis. 2005 Jun; 7(3):221-32; discussion 255-62. . View in PubMed

A potential role of the curry spice curcumin in Alzheimer's disease Curr Alzheimer Res. 2005 Apr; 2(2):131-6. . View in PubMed

Mitochondrial encephalomyopathy with lactic acidosis and stroke (MELAS) Rev Neurol Dis. 2005; 2(1):30-4. . View in PubMed

Spasmodic dysphonia in a patient with the A to G transition at nucleotide 8344 in mitochondrial DNA Mov Disord. 2003 Jun; 18(6):716-8. . View in PubMed

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