Rema Raman

Rema Raman

Professor of Neurology;Director, Biostatistics Core
ATR 9860 Mesa Rim Road Health Sciences Campus San Diego

Plasma Aß42/Aß40 and phospho-tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer's disease Alzheimers Dement. 2023 Nov 06. . View in PubMed

Eligibility rates among racially and ethnically diverse US participants in Phase 2 and Phase 3 placebo-controlled, double-blind, randomized trials of lecanemab and elenbecestat in early Alzheimer's disease Ann Neurol. 2023 Oct 13. . View in PubMed

Study design and methods: US. study to protect brain health through lifestyle intervention to reduce risk (U. S. POINTER). Alzheimers Dement. 2023 Sep 30. . View in PubMed

Ascertainment and Statistical Issues for Randomized Trials of Cardiovascular Interventions for Cognitive Impairment and Dementia: Dementia Series Hypertension. 2023 Sep 21. . View in PubMed

Trial of Solanezumab in Preclinical Alzheimer's Disease N Engl J Med. 2023 Sep 21; 389(12):1096-1107. . View in PubMed

Natural cubic splines for the analysis of Alzheimer's clinical trials Pharm Stat. 2023 May-Jun; 22(3):508-519. . View in PubMed

Safety and tolerability of lumbar puncture for the evaluation of Alzheimer's disease Alzheimers Dement (Amst). 2023 Apr-Jun; 15(2):e12431. . View in PubMed

The Nairobi Declaration-Reducing the burden of dementia in low- and middle-income countries (LMICs): Declaration of the 2022 Symposium on Dementia and Brain Aging in LMICs Alzheimers Dement. 2023 Mar 11. . View in PubMed

The AHEAD 3-45 Study: Design of a prevention trial for Alzheimer's disease Alzheimers Dement. 2023 04; 19(4):1227-1233. . View in PubMed

Improving generalizability and study design of Alzheimer's disease cohort studies in the United States by including under-represented populations Alzheimers Dement. 2023 04; 19(4):1549-1557. . View in PubMed

Evaluation of Blood-Based Plasma Biomarkers as Potential Markers of Amyloid Burden in Preclinical Alzheimer's Disease J Alzheimers Dis. 2023; 92(1):95-107. . View in PubMed

Evaluation of Neighborhood-Level Disadvantage and Cognition in Mexican American and Non-Hispanic White Adults 50 Years and Older in the US JAMA Netw Open. 2023 08 01; 6(8):e2325325. . View in PubMed

Protective effects of sleep duration and physical activity on cognitive performance are influenced by ß-amyloid and brain volume but not tau burden among cognitively unimpaired older adults Neuroimage Clin. 2023; 39:103460. . View in PubMed

Centralizing prescreening data collection to inform data-driven approaches to clinical trial recruitment Alzheimers Res Ther. 2023 05 02; 15(1):88. . View in PubMed

What Should the Goals Be for Diverse Recruitment in Alzheimer Clinical Trials? JAMA Neurol. 2022 Nov 01; 79(11):1097-1098.. View in PubMed

Screening and enrollment of underrepresented ethnocultural and educational populations in the Alzheimer's Disease Neuroimaging Initiative (ADNI) Alzheimers Dement. 2022 Feb 25. . View in PubMed

Alzheimer's disease research progress in the Mediterranean region: The Alzheimer's Association International Conference Satellite Symposium Alzheimers Dement. 2022 10; 18(10):1957-1968. . View in PubMed

Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos & Alzheimer's Symposium Alzheimers Dement. 2022 09; 18(9):1677-1686. . View in PubMed

Early-stage Alzheimer disease: getting trial-ready Nat Rev Neurol. 2022 07; 18(7):389-399. . View in PubMed

Attitudes about involvement in hypothetical clinical trial protocols in Mexican and Mexican-American at risk for autosomal dominant Alzheimer's disease Alzheimers Res Ther. 2022 11 15; 14(1):173. . View in PubMed

Intranasal insulin modulates cerebrospinal fluid markers of neuroinflammation in mild cognitive impairment and Alzheimer's disease: a randomized trial Sci Rep. 2022 01 25; 12(1):1346. . View in PubMed

Enhanced Association of Tau Pathology and Cognitive Impairment in Mild Cognitive Impairment Subjects with Behavior Symptoms J Alzheimers Dis. 2022; 87(2):557-568. . View in PubMed

Tackling a Major Deficiency of Diversity in Alzheimer's Disease Therapeutic Trials: An CTAD Task Force Report J Prev Alzheimers Dis. 2022; 9(3):388-392. . View in PubMed

Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease: A Truncated Randomized Phase 2b/3 Clinical Trial JAMA Neurol. 2021 03 01; 78(3):293-301. . View in PubMed

The Impact of Amyloid Burden and APOE on Rates of Cognitive Impairment in Late Life Depression J Alzheimers Dis. 2021; 80(3):991-1002. . View in PubMed

Late-Life Depression Is Associated With Reduced Cortical Amyloid Burden: Findings From the Alzheimer's Disease Neuroimaging Initiative Depression Project Biol Psychiatry. 2021 04 15; 89(8):757-765. . View in PubMed

The Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT-AD): A Novel Clinical Trials Training Program J Prev Alzheimers Dis. 2021; 8(3):286-291. . View in PubMed

Disparities by Race and Ethnicity Among Adults Recruited for a Preclinical Alzheimer Disease Trial JAMA Netw Open. 2021 07 01; 4(7):e2114364. . View in PubMed

Impact of the COVID-19 pandemic on statistical design and analysis plans for multidomain intervention clinical trials: Experience from World-Wide FINGERS Alzheimers Dement (N Y). 2021; 7(1):e12143. . View in PubMed

Predicting amyloid risk by machine learning algorithms based on the A4 screen data: Application to the Japanese Trial-Ready Cohort study Alzheimers Dement (N Y). 2021; 7(1):e12135. . View in PubMed

Brain amyloid burden, sleep, and 24-hour rest/activity rhythms: screening findings from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration Studies Sleep Adv. 2021; 2(1):zpab015. . View in PubMed

Tobacco use and E-cigarette regulation: Perspectives of University Students in the Asia-Pacific Addict Behav. 2020 08; 107:106420. . View in PubMed

World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia Alzheimers Dement. 2020 07; 16(7):1078-1094. . View in PubMed

Levetiracetam Versus Phenobarbital for Neonatal Seizures: A Randomized Controlled Trial Pediatrics. 2020 06; 145(6). . View in PubMed

TRC-PAD: Accelerating Recruitment of AD Clinical Trials through Innovative Information Technology J Prev Alzheimers Dis. 2020; 7(4):226-233. . View in PubMed

The Trial-Ready Cohort for Preclinical/Prodromal Alzheimer's Disease (TRC-PAD) Project: An Overview J Prev Alzheimers Dis. 2020; 7(4):208-212. . View in PubMed

Statistical methods in handling placebo effect Int Rev Neurobiol. 2020; 153:103-120. . View in PubMed

Instrumental activities of daily living, amyloid, and cognition in cognitively normal older adults screening for the A4 Study Alzheimers Dement (Amst). 2020; 12(1):e12118. . View in PubMed

Predicting Amyloid Burden to Accelerate Recruitment of Secondary Prevention Clinical Trials J Prev Alzheimers Dis. 2020; 7(4):213-218. . View in PubMed

Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals JAMA Neurol. 2020 06 01; 77(6):735-745. . View in PubMed

Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia: A Randomized Clinical Trial JAMA Neurol. 2020 09 01; 77(9):1099-1109. . View in PubMed

Short-term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment JAMA Neurol. 2020 12 01; 77(12):1504-1513. . View in PubMed

Viewpoint: Futility Analyses in Alzheimer's Disease (AD) Clinical Trials: A Risky Business J Prev Alzheimers Dis. 2020; 7(3):195-196. . View in PubMed

Authors response to D Umbricht, letter to the editor referring Futility Analyses in Alzheimer's Disease (AD) Clinical Trials: A Risky BusinessThe Journal of Prevention of Alzheimer's Disease, 2020. J Prev Alzheimers Dis. 2020; 7(4):300. . View in PubMed

The Trial-Ready Cohort for Preclinical and Prodromal Alzheimer's Disease (TRC-PAD): Experience from the First 3 Years J Prev Alzheimers Dis. 2020; 7(4):234-241. . View in PubMed

Effect of AZD0530 on Cerebral Metabolic Decline in Alzheimer Disease: A Randomized Clinical Trial JAMA Neurol. 2019 Oct 01; 76(10):1219-1229. . View in PubMed

A mixed-methods study of cultural beliefs about dementia and genetic testing among Mexicans and Mexican-Americans at-risk for autosomal dominant Alzheimer's disease J Genet Couns. 2019 10; 28(5):921-932. . View in PubMed

Preliminary Results of a Trial of Atabecestat in Preclinical Alzheimer's Disease N Engl J Med. 2019 04 11; 380(15):1483-1485. . View in PubMed

International chicken trade and increased risk for introducing or reintroducing highly pathogenic avian influenza A (H5N1) to uninfected countries Infect Dis Model. 2017 Nov; 2(4):412-418. . View in PubMed

A randomized controlled trial of ganaxolone in posttraumatic stress disorder Psychopharmacology (Berl). 2017 Aug; 234(15):2245-2257. . View in PubMed

Randomized controlled trial of acceptance and commitment therapy for distress and impairment in OEF/OIF/OND veterans Psychol Trauma. 2017 Aug; 9(Suppl 1):74-84. . View in PubMed

A phase 3 trial of IV immunoglobulin for Alzheimer disease Neurology. 2017 May 02; 88(18):1768-1775. . View in PubMed

Telephone Problem Solving for Service Members with Mild Traumatic Brain Injury: A Randomized, Clinical Trial J Neurotrauma. 2017 01 15; 34(2):313-321. . View in PubMed

EU/US/CTAD Task Force: Lessons Learned from Recent and Current Alzheimer's Prevention Trials J Prev Alzheimers Dis. 2017; 4(2):116-124. . View in PubMed

Cross-validation of optimized composites for preclinical Alzheimer's disease Alzheimers Dement (N Y). 2017 Jan; 3(1):123-129. . View in PubMed

Accuracy of Stroke Diagnosis in Telestroke-Guided Tissue Plasminogen Activator Patients J Stroke Cerebrovasc Dis. 2016 Dec; 25(12):2942-2946. . View in PubMed

Visual Determination of Conjugate Eye Deviation on Computed Tomography Scan Predicts Diagnosis of Stroke Code Patients J Stroke Cerebrovasc Dis. 2016 Dec; 25(12):2809-2813. . View in PubMed

Neurocognitive Models of Medical Decision-Making Capacity in Traumatic Brain Injury Across Injury Severity J Head Trauma Rehabil. 2016 May-Jun; 31(3):E49-59. . View in PubMed

Randomized Placebo-Controlled Trial of Methylphenidate or Galantamine for Persistent Emotional and Cognitive Symptoms Associated with PTSD and/or Traumatic Brain Injury Neuropsychopharmacology. 2016 Apr; 41(5):1191-8. . View in PubMed

Results of the ICTuS 2 Trial (Intravascular Cooling in the Treatment of Stroke 2) Stroke. 2016 12; 47(12):2888-2895. . View in PubMed

Changes in Neuropsychiatric Inventory Associated with Semagacestat Treatment of Alzheimer's Disease J Alzheimers Dis. 2016 08 10; 54(1):373-81. . View in PubMed

Feasibility and Safety of Using External Counterpulsation to Augment Cerebral Blood Flow in Acute Ischemic Stroke-The Counterpulsation to Upgrade Forward Flow in Stroke (CUFFS) Trial J Stroke Cerebrovasc Dis. 2015 Nov; 24(11):2596-604. . View in PubMed

Accuracy of First Recorded "Last Known Normal" Times of Stroke Code Patients J Stroke Cerebrovasc Dis. 2015 Nov; 24(11):2467-73. . View in PubMed

A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease Neurology. 2015 Oct 20; 85(16):1383-91. . View in PubMed

Mental Disorders, Comorbidity, and Pre-enlistment Suicidal Behavior Among New Soldiers in the US. Army: Results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS). Suicide Life Threat Behav. 2015 Oct; 45(5):588-599. . View in PubMed

Defining mild stroke: outcomes analysis of treated and untreated mild stroke patients J Stroke Cerebrovasc Dis. 2015 Jun; 24(6):1276-81. . View in PubMed

The "DeyeCOM Sign": Predictive Value in Acute Stroke Code Evaluations J Stroke Cerebrovasc Dis. 2015 Jun; 24(6):1299-304. . View in PubMed

Comparing recruitment, retention, and safety reporting among geographic regions in multinational Alzheimer's disease clinical trials Alzheimers Res Ther. 2015; 7(1):39. . View in PubMed

Alzheimers Res Ther. 2015; 7(1):36. . View in PubMed

Prevalence and correlates of suicidal behavior among new soldiers in the US. Army: results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS). Depress Anxiety. 2015 Jan; 32(1):3-12. . View in PubMed

Concussion treatment after combat trauma: development of a telephone based, problem solving intervention for service members Contemp Clin Trials. 2015 Jan; 40:54-62. . View in PubMed

Association of Hispanic ethnicity with acute ischemic stroke care processes and outcomes Ethn Dis. 2015; 25(1):19-23. . View in PubMed

Alzheimer's disease progression by geographical region in a clinical trial setting Alzheimers Res Ther. 2015; 7(1):43. . View in PubMed

Estimating long-term multivariate progression from short-term data Alzheimers Dement. 2014 Oct; 10(5 Suppl):S400-10. . View in PubMed

Dramatic decline of respiratory illness among US military recruits after the renewed use of adenovirus vaccines Clin Infect Dis. 2014 Oct; 59(7):962-8. . View in PubMed

The Alzheimer's disease cooperative study prevention instrument project: longitudinal outcome of behavioral measures as predictors of cognitive decline Dement Geriatr Cogn Dis Extra. 2014 Sep-Dec; 4(3):509-16. . View in PubMed

Individuals with chronic traumatic brain injury improve walking speed and mobility with intensive mobility training Arch Phys Med Rehabil. 2014 Aug; 95(8):1454-60. . View in PubMed

The preclinical Alzheimer cognitive composite: measuring amyloid-related decline JAMA Neurol. 2014 Aug; 71(8):961-70. . View in PubMed

Self-reported smoking and musculoskeletal overuse injury among male and female US. Marine Corps recruits. Mil Med. 2014 Jul; 179(7):735-43. . View in PubMed

Imaging negative stroke: diagnoses and outcomes in intravenous tissue plasminogen activator-treated patients J Stroke Cerebrovasc Dis. 2014 May-Jun; 23(5):1046-50. . View in PubMed

A two-site pilot randomized 3 day trial of high dose left prefrontal repetitive transcranial magnetic stimulation (rTMS) for suicidal inpatients Brain Stimul. 2014 May-Jun; 7(3):421-31. . View in PubMed

Does symptom onset to primary stroke center time goals affect stroke outcome? J Stroke Cerebrovasc Dis. 2014 May-Jun; 23(5):993-1000.. View in PubMed

Pooled assessment of computed tomography interpretation by vascular neurologists in the STRokE DOC telestroke network J Stroke Cerebrovasc Dis. 2014 Mar; 23(3):511-5. . View in PubMed

Accounting for functional loss in Alzheimer's disease and dementia with Lewy bodies: beyond cognition Alzheimers Dement. 2014 Mar; 10(2):171-8. . View in PubMed

Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease N Engl J Med. 2014 Jan 23; 370(4):311-21. . View in PubMed

Effect of head impacts on diffusivity measures in a cohort of collegiate contact sport athletes Neurology. 2014 Jan 07; 82(1):63-9. . View in PubMed

Weight patterns before and after total joint arthroplasty and characteristics associated with weight change Perm J. 2014; 18(1):25-31. . View in PubMed

Endovascular therapeutic hypothermia for acute ischemic stroke: ICTuS 2/3 protocol Int J Stroke. 2014 Jan; 9(1):117-25. . View in PubMed

Epidemiology of pathogen-specific respiratory infections among three US populations PLoS One. 2014; 9(12):e114871. . View in PubMed

Parametric comparisons of intracranial mechanical responses from three validated finite element models of the human head Ann Biomed Eng. 2014 Jan; 42(1):11-24. . View in PubMed

Trends in antihypertensive drug prescription patterns among ambulatory stroke patients in the United States, 2000-2009 J Stroke Cerebrovasc Dis. 2013 Nov; 22(8):e568-75. . View in PubMed

Diffusion-weighted imaging-fluid attenuated inversion recovery mismatch in nocturnal stroke patients with unknown time of onset J Stroke Cerebrovasc Dis. 2013 Oct; 22(7):972-7. . View in PubMed

A phase 3 trial of semagacestat for treatment of Alzheimer's disease N Engl J Med. 2013 Jul 25; 369(4):341-50. . View in PubMed

Determinants of Pneumonia Risk During Endovascular Hypothermia Ther Hypothermia Temp Manag. 2013 Mar; 3(1):24-27. . View in PubMed

Effect of study partner on the conduct of Alzheimer disease clinical trials Neurology. 2013 Jan 15; 80(3):282-8. . View in PubMed

The association of self-reported measures with poor training outcomes among male and female US. Navy recruits. Mil Med. 2013 Jan; 178(1):43-9. . View in PubMed

Effects of varying duty cycle and pulse width on high-intensity focused ultrasound (HIFU)-induced transcranial thrombolysis J Ther Ultrasound. 2013; 1:18. . View in PubMed

Intravenous tissue plasminogen activator for patients with minor ischemic stroke J Stroke Cerebrovasc Dis. 2012 Nov; 21(8):732-6. . View in PubMed

CT interpretation in a telestroke network: agreement among a spoke radiologist, hub vascular neurologist, and hub neuroradiologist Stroke. 2012 Nov; 43(11):3095-7. . View in PubMed

Late night activity regarding stroke codes: LuNAR strokes Int J Stroke. 2012 Aug; 7(6):473-6. . View in PubMed

Age and rate of cognitive decline in Alzheimer disease: implications for clinical trials Arch Neurol. 2012 Jul; 69(7):901-5. . View in PubMed

Determinants of effective cooling during endovascular hypothermia Neurocrit Care. 2012 Jun; 16(3):413-20. . View in PubMed

Assessment of long-term outcomes for the STRokE DOC telemedicine trial J Stroke Cerebrovasc Dis. 2012 May; 21(4):259-64. . View in PubMed

Efficacy of telemedicine for stroke: pooled analysis of the Stroke Team Remote Evaluation Using a Digital Observation Camera (STRokE DOC) and STRokE DOC Arizona telestroke trials Telemed J E Health. 2012 Apr; 18(3):230-7. . View in PubMed

Incidence of new-onset seizures in mild to moderate Alzheimer disease Arch Neurol. 2012 Mar; 69(3):368-72. . View in PubMed

Evaluating transdiagnostic treatment for distress and impairment in veterans: a multi-site randomized controlled trial of Acceptance and Commitment Therapy Contemp Clin Trials. 2012 Jan; 33(1):116-23. . View in PubMed

Comprehensive stroke centers and the 'weekend effect': the SPOTRIAS experience Cerebrovasc Dis. 2012; 34(5-6):424-9. . View in PubMed

Two-hour improvement of patients in the National Institute of Neurological Disorders and Stroke trials and prediction of final outcome Stroke. 2011 Nov; 42(11):3163-7. . View in PubMed

Chronic divalproex sodium to attenuate agitation and clinical progression of Alzheimer disease Arch Gen Psychiatry. 2011 Aug; 68(8):853-61. . View in PubMed

Adding delayed recall to the Alzheimer Disease Assessment Scale is useful in studies of mild cognitive impairment but not Alzheimer disease Alzheimer Dis Assoc Disord. 2011 Apr-Jun; 25(2):122-7. . View in PubMed

Therapeutic hypothermia is associated with a decrease in urine output in acute stroke patients Resuscitation. 2010 Dec; 81(12):1642-7. . View in PubMed

Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial JAMA. 2010 Nov 03; 304(17):1903-11. . View in PubMed

Alberta Stroke Program Early CT Score (ASPECTS) in patients with wake-up stroke J Stroke Cerebrovasc Dis. 2010 Nov-Dec; 19(6):475-9. . View in PubMed

Intravenous thrombolysis plus hypothermia for acute treatment of ischemic stroke (ICTuS-L): final results Stroke. 2010 Oct; 41(10):2265-70. . View in PubMed

Influence of apolipoprotein E varepsilon4 on rates of cognitive and functional decline in mild cognitive impairment Alzheimers Dement. 2010 Sep; 6(5):412-9. . View in PubMed

Gender differences in acute stroke treatment: the University of California San Diego experience Stroke. 2010 Aug; 41(8):1755-7. . View in PubMed

Analysis of the National Institute of Neurological Disorders and Stroke tissue plasminogen activator studies following European Cooperative Acute Stroke Study III patient selection criteria J Stroke Cerebrovasc Dis. 2010 Jul-Aug; 19(4):290-3. . View in PubMed

Stroke team remote evaluation using a digital observation camera in Arizona: the initial mayo clinic experience trial Stroke. 2010 Jun; 41(6):1251-8. . View in PubMed

Clinical Core of the Alzheimer's Disease Neuroimaging Initiative: progress and plans Alzheimers Dement. 2010 May; 6(3):239-46. . View in PubMed

Prevalence and psychological correlates of traumatic brain injury in operation iraqi freedom J Head Trauma Rehabil. 2010 Jan-Feb; 25(1):1-8. . View in PubMed

MRI substudy participation in Alzheimer disease (AD) clinical trials: baseline comparability of a substudy sample to entire study population Alzheimer Dis Assoc Disord. 2009 Oct-Dec; 23(4):333-6. . View in PubMed

Injury-specific predictors of posttraumatic stress disorder Injury. 2009 Sep; 40(9):1004-10. . View in PubMed

Characteristics and performance of a modified version of the ADCS-CGIC CIBIC+ for mild cognitive impairment clinical trials Alzheimer Dis Assoc Disord. 2009 Jul-Sep; 23(3):260-7. . View in PubMed

National Institutes of Health Stroke Scale certification is reliable across multiple venues Stroke. 2009 Jul; 40(7):2507-11. . View in PubMed

Clinical interview assessment of financial capacity in older adults with mild cognitive impairment and Alzheimer's disease J Am Geriatr Soc. 2009 May; 57(5):806-14. . View in PubMed

Psychological correlates of battle and nonbattle injury among Operation Iraqi Freedom veterans Mil Med. 2009 Mar; 174(3):224-31. . View in PubMed

Can comprehensive stroke centers erase the 'weekend effect'? Cerebrovasc Dis. 2009; 27(2):107-13.. View in PubMed

In vitro sonothrombolysis with duplex ultrasound: first results using a simplified model Cerebrovasc Dis. 2009; 28(4):365-70. . View in PubMed

Plasma urate and progression of mild cognitive impairment Neurodegener Dis. 2009; 6(1-2):23-8. . View in PubMed

Efficacy of site-independent telemedicine in the STRokE DOC trial: a randomised, blinded, prospective study Lancet Neurol. 2008 Sep; 7(9):787-95. . View in PubMed

Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease Arch Neurol. 2008 Aug; 65(8):1031-8. . View in PubMed

Awareness of deficits in financial abilities in patients with mild cognitive impairment: going beyond self-informant discrepancy Am J Geriatr Psychiatry. 2008 Aug; 16(8):650-9. . View in PubMed

Reliability of site-independent telemedicine when assessed by telemedicine-naive stroke practitioners J Stroke Cerebrovasc Dis. 2008 Jul-Aug; 17(4):181-6. . View in PubMed

The first puff: forces in smoking initiation among Californians of Korean descent Nicotine Tob Res. 2007 Dec; 9(12):1277-86. . View in PubMed

Diffusion of cancer education information through a Latino community health advisor program Prev Med. 2007 Aug-Sep; 45(2-3):135-8. . View in PubMed

Quetiapine for agitation or psychosis in patients with dementia and parkinsonism Neurology. 2007 Apr 24; 68(17):1356-63. . View in PubMed

An expedited code stroke protocol is feasible and safe Stroke. 2006 Dec; 37(12):2935-9. . View in PubMed

ADCS Prevention Instrument Project: the Mail-In Cognitive Function Screening Instrument (MCFSI) Alzheimer Dis Assoc Disord. 2006 Oct-Dec; 20(4 Suppl 3):S170-8. . View in PubMed

ADCS Prevention Instrument Project: ADCS-clinicians' global impression of change scales (ADCS-CGIC), self-rated and study partner-rated versions Alzheimer Dis Assoc Disord. 2006 Oct-Dec; 20(4 Suppl 3):S124-38. . View in PubMed

ADCS Prevention Instrument Project: behavioral measures in primary prevention trials Alzheimer Dis Assoc Disord. 2006 Oct-Dec; 20(4 Suppl 3):S147-51. . View in PubMed

A mixed-effects regression model for three-level ordinal response data Stat Med. 2005 Nov 15; 24(21):3331-45. . View in PubMed

NIHSS training and certification using a new digital video disk is reliable Stroke. 2005 Nov; 36(11):2446-9. . View in PubMed

Divalproex sodium in nursing home residents with possible or probable Alzheimer Disease complicated by agitation: a randomized, controlled trial Am J Geriatr Psychiatry. 2005 Nov; 13(11):942-9. . View in PubMed

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease Science. 2005 Feb 25; 307(5713):1282-8. . View in PubMed

J Natl Med Assoc. 2003 Jun; 95(6):423-32. . View in PubMed

Heterotopia of the tonsil J Laryngol Otol. 1996 Jun; 110(6):611-2. . View in PubMed

Rema Raman is a Professor of Neurology at Keck School of Medicine of USC and the Director of Biostatistics at the USC Alzheimer’s Therapeutic Research Institute (ATRI). She is the lead of the Biostatistics Unit and the co-lead of the Recruitment Unit for the Alzheimer’s Clinical Trials Consortium (ACTC).
Dr. Raman has focused her academic career in the design, conduct and analysis of clinical trials in neurology. She has extensive experience as a collaborative biostatistician and clinical trialist, serving in the leadership team of several highly integrated and interdisciplinary research programs conducting clinical research in Alzheimer¹s disease, acute stroke, post-traumatic stress disorder, and traumatic brain injury. Her primary statistical research interests are in correlated and missing data issues, design and analysis of efficient clinical trials and cohort studies, centralized and adaptive statistical monitoring approaches, and effective safety monitoring.
Dr. Raman is deeply committed to the effective teaching of biostatistics and clinical trial methodology to medical students, graduate students, clinical fellows and other clinical researchers. She has taught clinical trials to graduate students and medical residents/fellows and Biostatistics to basic science and public health graduate students as well as medical students. She has trained physicians on biostatistics and clinical research methodology and provided the statistical mentorship to many research projects. She is co-director of the Institute of Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT-AD), a course that aims to educate and promote diversity among research professionals and future principal investigators in the field of Alzheimer’s Disease and Related Disorders research, and the co-Chair of the ACTC Inclusion, Diversity and Education in Alzheimer’s disease Clinical Trials (IDEA-CT) committee.
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