{"id":3008,"date":"2019-12-20T02:51:18","date_gmt":"2019-12-20T10:51:18","guid":{"rendered":"https:\/\/keck.usc.edu\/news\/usc-stem-cell-scientist-rong-lu-named-leukemia-lymphoma-society-scholar\/"},"modified":"2023-11-26T08:29:29","modified_gmt":"2023-11-26T16:29:29","slug":"usc-stem-cell-scientist-rong-lu-named-leukemia-lymphoma-society-scholar","status":"publish","type":"post","link":"https:\/\/keck.usc.edu\/news\/usc-stem-cell-scientist-rong-lu-named-leukemia-lymphoma-society-scholar\/","title":{"rendered":"USC Stem Cell scientist Rong Lu named Leukemia & Lymphoma Society Scholar"},"content":{"rendered":"\n \n \n\n\n\n\n\n\n\n
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\n\n \n Press Release<\/span>\n\n\n\n<\/div>\n \n \n
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USC Stem Cell scientist Rong Lu named Leukemia & Lymphoma Society Scholar<\/h1>\n\n\n<\/div>\n \n \n
\n \n December 20, 2019<\/span>\n <\/div>\n \n \n
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\u201cIt\u2019s a new research effort in the lab and also a new research area for myself, because I\u2019m trained as a stem cell biologist,\u201d said Lu, who is now a Leukemia & Lymphoma Society Scholar. \u201cWe will use a tool that we developed for studying stem cells to study leukemia cells from patients with acute lymphoblastic leukemia.\u201d<\/p>\n

The tool is a system for labeling individual cells with unique \u201cbarcodes,\u201d composed of short sequences of genetic information.<\/p>\n

The Lu Lab is using their barcode tool to label leukemia cells and then transplanting these malignant cells into mice undergoing cancer treatment regimens. The lab is tracking the individual barcoded leukemia cells in order to learn about their regulatory mechanisms\u2014including mutations and other changes that enable the most aggressive leukemia cells to initiate cancer, proliferate, migrate, and resist treatment.<\/p>\n

\u201cWe expect to identify the key cellular and molecular events that drive leukemia onset and relapse, with the goal of improving both diagnosis and treatment for patients,\u201d said Lu.<\/p>\n

In order to create this clinically relevant model of leukemia, Lu is collaborating with two physician-scientists: Akil A. Merchant at Cedars-Sinai Medical Center; and Markus M\u00fcschen at City of Hope.<\/p>\n

\u201cI\u2019ve gained insights into how difficult clinical decisions are made,\u201d said Lu, who is also a Richard N. Merkin Assistant Professor of Stem Cell Biology and Regenerative Medicine, Biomedical Engineering, Medicine and Gerontology at USC. \u201cThere are so many questions that physicians have in their minds, and they love to talk with someone who can solve these problems. I\u2019m quite excited about the conversation with them, and I\u2019ve learned a lot during the process.\u201d<\/p>\n

According to Lee Greenberger, chief scientific officer at the Leukemia & Lymphoma Society, \u201cBringing the state-of-the-art expertise of Dr. Lu to understand the evolution of mutant cells that drive leukemia is a critical step toward improving treatments for this deadly disease. Beyond this, scientists supported by our Career Development Program over the past 70 years have consistently demonstrated that these grants are foundational for advancing careers and pay back many times over in the years ahead. We are delighted to support the work of Dr. Lu.\u201d<\/p>\n<\/div>\n\n\n\n<\/div>\n <\/div>\n\n\n <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"

Why do some leukemia patients have more aggressive disease, and why do some of their cancer cells resist treatment? USC Stem Cell scientist Rong Lu is tackling these critical questions with $550,000 of support from the Leukemia & Lymphoma Society\u2019s Career Development Program.<\/p>\n","protected":false},"author":168,"featured_media":3009,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[78],"class_list":["post-3008","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-release","tag-uncategorized"],"acf":[],"yoast_head":"\nUSC Stem Cell scientist Rong Lu named Leukemia & Lymphoma Society Scholar<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/keck.usc.edu\/news\/usc-stem-cell-scientist-rong-lu-named-leukemia-lymphoma-society-scholar\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"USC Stem Cell scientist Rong Lu named Leukemia & Lymphoma Society Scholar\" \/>\n<meta property=\"og:description\" content=\"Why do some leukemia patients have more aggressive disease, and why do some of their cancer cells resist treatment? 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