{"id":3027,"date":"2020-01-21T00:14:55","date_gmt":"2020-01-21T08:14:55","guid":{"rendered":"https:\/\/keck.usc.edu\/news\/from-the-conversation-a-long-sought-dream-for-sleep-apnea-patients-may-be-in-closer-reach\/"},"modified":"2025-10-23T13:32:47","modified_gmt":"2025-10-23T20:32:47","slug":"from-the-conversation-a-long-sought-dream-for-sleep-apnea-patients-may-be-in-closer-reach","status":"publish","type":"post","link":"https:\/\/keck.usc.edu\/news\/from-the-conversation-a-long-sought-dream-for-sleep-apnea-patients-may-be-in-closer-reach\/","title":{"rendered":"From The Conversation: A long-sought dream for sleep apnea patients may be in closer reach"},"content":{"rendered":"\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--article-hero \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--article-hero\"\n    \n      >\n\n    \n  <div class=\"text-container\">\n              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <span>Press Release<\/span>\n\n\n\n<\/div>\n    \n              \n<div class=\"f--field f--page-title\">\n\n    \n  <h1>From The Conversation: A long-sought dream for sleep apnea patients may be in closer reach<\/h1>\n\n\n<\/div>\n    \n    \n          <div class=\"meta\">\n        \n                  <span class=\"date\">January 21, 2020<\/span>\n              <\/div>\n    \n              \n<div class=\"f--field f--embed\">\n\n    \n  <div class=\"heateor_sss_sharing_container heateor_sss_horizontal_sharing\" data-heateor-ss-offset=\"0\" data-heateor-sss-href='https:\/\/keck.usc.edu\/news\/from-the-conversation-a-long-sought-dream-for-sleep-apnea-patients-may-be-in-closer-reach\/'><div class=\"heateor_sss_sharing_ul\"><a aria-label=\"Facebook\" class=\"heateor_sss_facebook\" href=\"https:\/\/www.facebook.com\/sharer\/sharer.php?u=https%3A%2F%2Fkeck.usc.edu%2Fnews%2Ffrom-the-conversation-a-long-sought-dream-for-sleep-apnea-patients-may-be-in-closer-reach%2F\" title=\"Facebook\" rel=\"nofollow 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data-srcset=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/Apnea-Feature-768x432.jpg 768w\"          data-sizes=\"(min-width:1200px) 75vw, (min-width:768px) 83vw, 100vw\"          class=\"lazyload\"\n        \n        alt=\"sleep apnea man\"\n        \n                                      \/>\n\n    \n          <figcaption>Sleep loss caused by apnea is a major cause of health problems \u2013 and misery. (Photo\/Shutterstock)<\/figcaption>\n    <\/figure>\n    \n  \n  \n\n<\/div>\n  \n\n  <\/div><\/div>\n\r\n\r\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>For millions of people who suffer from sleep apnea, getting a good night\u2019s sleep is an elusive dream. Patients with\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23910433\" target=\"_blank\" rel=\"noopener noreferrer\">obstructive sleep apnea<\/a>\u00a0have blockages of breathing while they sleep, leading to snoring, disruption of sleep and the drowsiness or fatigue that often occur. The ailment also can lead to\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23910433\" target=\"_blank\" rel=\"noopener noreferrer\">serious health problems<\/a>\u00a0such as high blood pressure and a risk of heart attack or stroke.<\/p>\n<div id=\"attachment_10053\" class=\"wp-caption alignright\">\n<figure id=\"attachment_120026\" aria-describedby=\"caption-attachment-120026\" style=\"width: 378px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-120026 size-full\" src=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/Kezirian-Eric_.jpg\" alt=\"\" width=\"378\" height=\"450\" \/><figcaption id=\"caption-attachment-120026\" class=\"wp-caption-text\">Article author Eric Kezirian, MD, MPH. (Photo\/Ricardo Carrasco III)<\/figcaption><\/figure>\n<\/div>\n<p>Sleep apnea affects about\u00a0<a href=\"https:\/\/www.sleepfoundation.org\/sleep-apnea\" target=\"_blank\" rel=\"noopener noreferrer\">18 million adults<\/a>\u00a0in the U.S.<br \/>\nand an estimated\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31300334\" target=\"_blank\" rel=\"noopener noreferrer\">1 billion people<\/a>\u00a0worldwide. Many are treated successfully with\u00a0<a href=\"https:\/\/www.sleep.org\/articles\/what-is-cpap-machine\/\" target=\"_blank\" rel=\"noopener noreferrer\">continuous positive airway pressure (CPAP)<\/a>\u00a0machines that allow them to breathe by keeping their airways open.<\/p>\n<p>But about one-third of patients who do not tolerate continuous positive airway pressure machines must look for other options, including surgery or oral appliances. There is a wide range of surgical procedures that open the space for breathing in the throat by removing or repositioning structures such as the soft palate (back of the roof of the mouth) or tongue. Although many patients do well with surgery, the results are far from perfect.<\/p>\n<p>As a sleep surgeon and professor of\u00a0<a href=\"https:\/\/www.webmd.com\/cold-and-flu\/ear-infection\/qa\/what-is-an-otolaryngologist\" target=\"_blank\" rel=\"noopener noreferrer\">otolaryngology<\/a>\u00a0and head and neck surgery, I have focused on evaluation and surgery for obstructive sleep apnea and snoring. My\u00a0<a href=\"https:\/\/www.researchgate.net\/scientific-contributions\/39965557_Eric_J_Kezirian\" target=\"_blank\" rel=\"noopener noreferrer\">research<\/a>\u00a0has examined why some patients do well and others do not with surgical procedures, and if someone who doesn\u2019t fare well with surgery will also not tolerate other treatments.<\/p>\n<p><strong>A robber of breath, and of health<\/strong><\/p>\n<p>The dangers of apnea go beyond loss of sleep, although that is so important for those who have sleep apnea and seldom feel rested.<\/p>\n<p>While continuous positive airway pressure machines help thousands of people, many thousands more are not helped by them. Surgery and oral appliances are options in some cases.<\/p>\n<div id=\"attachment_10054\" class=\"wp-caption alignright\">\n<figure id=\"attachment_120025\" aria-describedby=\"caption-attachment-120025\" style=\"width: 450px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-120025 size-full\" src=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/Apnea-image-1.jpg\" alt=\"\" width=\"450\" height=\"300\" \/><figcaption id=\"caption-attachment-120025\" class=\"wp-caption-text\">Some patients find relief with the use of a CPAP machine, but it isn\u2019t the best option for everyone. (Photo\/Shutterstock)<\/figcaption><\/figure>\n<\/div>\n<p>Oral appliances, mouthpieces that typically open the space for breathing by holding the lower jaw forward,\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24533007\" target=\"_blank\" rel=\"noopener noreferrer\">can work well<\/a>. But, they do not work at all if a patient is not comfortable sleeping with it. And many are not.<\/p>\n<p>Surgery is an option in this group, but even surgery, which traditionally moves or repositions tissue, has not always helped.<\/p>\n<p>A device that can be surgically implanted to stimulate the tongue has been showing promise since 2011.<\/p>\n<p>The Food and Drug Administration, based on a study showing that the procedure\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24401051\" target=\"_blank\" rel=\"noopener noreferrer\">provides a major improvement in sleep apnea in about two-thirds of patients<\/a>, approved the device in 2014.<\/p>\n<p>Keck Medicine of USC is part of a group of centers collecting data from sleep apnea patients treated with this product, called Upper Airway Stimulation, in a study paid for by the company. The Upper Airway Stimulation system is placed inside the body during a surgery. The system works by stimulating the nerve that controls tongue movement to move the tongue forward to open the space for breathing in the throat.<\/p>\n<p><strong>An implanted device showing promise<\/strong><\/p>\n<p>Recently, we\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31234734\" target=\"_blank\" rel=\"noopener noreferrer\">examined data from nearly 300 patients<\/a>, including 80 with previous unsuccessful surgery. The typical measure of success for obstructive sleep apnea surgery has two parts: reducing by at least one-half the degree of sleep apnea and also leaving a patient with no or mild sleep apnea. We measure this by something called the apnea-hypopnea index, or the number of times per hour that breathing is blocked.<\/p>\n<div id=\"attachment_10055\" class=\"wp-caption alignright\">\n<figure id=\"attachment_120024\" aria-describedby=\"caption-attachment-120024\" style=\"width: 450px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-120024 size-full\" src=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/Apnea-image-2.jpg\" alt=\"\" width=\"450\" height=\"300\" \/><figcaption id=\"caption-attachment-120024\" class=\"wp-caption-text\">With the right treatment, many apnea sufferers can start to enjoy the benefits of a good night\u2019s sleep. (Photo\/Shutterstock)<\/figcaption><\/figure>\n<\/div>\n<p>Our study showed that there was no clear difference in results for patients\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31234734\" target=\"_blank\" rel=\"noopener noreferrer\">with and without previous surgery for obstructive sleep apnea<\/a>. While physicians have often assumed that patients who do not see good results after one surgery will not do well with other procedures, our study showed that this was not true for the group as a whole.<\/p>\n<p>We also looked at specific types of patients to see if they were doing better or worse than others. We saw a possible decreased chance of success in those who were not obese (body mass index below 29.1 kg\/m2). This appeared to be related to the fact that those without previous surgery had such a high likelihood of success (80%-90%), whereas those with previous unsuccessful surgery had the same likelihood as the rest of the patients. Future studies will examine this question with even more patients to check on whether these findings are clearer.<\/p>\n<p>As someone who treats patients with obstructive sleep apnea, I see many patients who have had surgery but still suffer from obstructive sleep apnea and are looking for more options. Our study showed that new treatments that improve patient care for sleep apnea can be worth exploring.<\/p>\n<p><em>This article was updated with the full name of Keck Medicine of USC.<\/em><\/p>\n<p><a href=\"https:\/\/keck.usc.edu\/faculty-search\/eric-james-kezirian\/\" target=\"_blank\" rel=\"noopener noreferrer\">Eric Kezirian<\/a>, Professor of Otolaryngology,\u00a0<em><a href=\"https:\/\/www.keckmedicine.org\/\" target=\"_blank\" rel=\"noopener noreferrer\">Keck Medicine of USC<\/a><\/em><\/p>\n<p>This article is republished from\u00a0<a href=\"http:\/\/theconversation.com\/\" target=\"_blank\" rel=\"noopener noreferrer\">The Conversation<\/a>\u00a0under a Creative Commons license. Read the\u00a0<a href=\"https:\/\/theconversation.com\/a-good-nights-sleep-a-long-sought-dream-for-sleep-apnea-patients-may-be-in-closer-reach-122026\" target=\"_blank\" rel=\"noopener noreferrer\">original article<\/a>.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":168,"featured_media":3028,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[56,59,16],"class_list":["post-3027","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-release","tag-featured","tag-featured-people","tag-otolaryngology"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - 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