{"id":339,"date":"2015-07-08T09:38:35","date_gmt":"2015-07-08T16:38:35","guid":{"rendered":"https:\/\/keck.usc.edu\/news\/usc-postdocs-win-doerr-stem-cell-challenge-grants\/"},"modified":"2023-11-26T08:16:26","modified_gmt":"2023-11-26T16:16:26","slug":"usc-postdocs-win-doerr-stem-cell-challenge-grants","status":"publish","type":"post","link":"https:\/\/keck.usc.edu\/news\/usc-postdocs-win-doerr-stem-cell-challenge-grants\/","title":{"rendered":"USC postdocs win Doerr Stem Cell Challenge Grants"},"content":{"rendered":"\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--article-hero \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--article-hero\"\n    \n      >\n\n    \n  <div class=\"text-container\">\n              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <span>Press Release<\/span>\n\n\n\n<\/div>\n    \n              \n<div class=\"f--field f--page-title\">\n\n    \n      <h1>USC postdocs win Doerr Stem Cell Challenge Grants<\/h1>\n\n\n<\/div>\n    \n    \n          <div class=\"meta\">\n        \n                  <span class=\"date\">July 08, 2015<\/span>\n              <\/div>\n    \n              \n<div class=\"f--field f--embed\">\n\n    \n  <div class=\"heateor_sss_sharing_container heateor_sss_horizontal_sharing\" data-heateor-ss-offset=\"0\" data-heateor-sss-href='https:\/\/keck.usc.edu\/news\/usc-postdocs-win-doerr-stem-cell-challenge-grants\/'><div class=\"heateor_sss_sharing_ul\"><a aria-label=\"Facebook\" class=\"heateor_sss_facebook\" href=\"https:\/\/www.facebook.com\/sharer\/sharer.php?u=https%3A%2F%2Fkeck.usc.edu%2Fnews%2Fusc-postdocs-win-doerr-stem-cell-challenge-grants%2F\" title=\"Facebook\" rel=\"nofollow noopener\" target=\"_blank\" style=\"font-size:32px!important;box-shadow:none;display:inline-block;vertical-align:middle\"><span class=\"heateor_sss_svg\" 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2.004.382 2.75 1.146l2.777 2.79c.75.747 1.12 1.66 1.12 2.737 0 1.105-.392 2.045-1.183 2.817l1.186 1.186c.774-.79 1.708-1.186 2.805-1.186 1.078 0 1.995.377 2.75 1.132l2.804 2.804c.754.755 1.13 1.672 1.13 2.75z\"\/><\/svg><\/span><\/a><\/div><div class=\"heateorSssClear\"><\/div><\/div>\n\n\n<\/div>\n        \n  <\/div>\n\n          \n<div class=\"f--field f--image\">\n\n    \n    \n    \n        <figure>\n    \n    \n    \n              \n      <img\n                            data-src=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/Doerr-600x432.jpg\"\n                    data-sizes=\"(min-width:1200px) 75vw, (min-width:768px) 83vw, 100vw\"          class=\"lazyload\"\n        \n        alt=\"Doerr\"\n        \n                                      \/>\n\n    \n          <figcaption>From left, Lindsey Mork, Michaela Patterson, Ang Li and Yuwei Li (Photos by Cristy Lytal)<\/figcaption>\n    <\/figure>\n    \n  \n  \n\n<\/div>\n  \n\n  <\/div><\/div>\n\r\n\r\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>Just as there are times when two heads are better than one, there are times when two labs are better than one. Thanks to the new Doerr Stem Cell Challenge Grants, teams of postdoctoral researchers from different USC labs have each received up to $10,000 in funding to pursue interdisciplinary one-year projects.<br \/>\n\u201cThe goal of the program is to stimulate new interdisciplinary stem cell research projects initiated and proposed by students and postdocs,\u201d said Andy McMahon,PhD, provost professor and the inaugural holder of the W. M. Keck Professorship of Stem Cell Biology and Regenerative Medicine and director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC. \u201cThis will enhance their creativity and independence, as well as their ability to compete for future grants supported by agencies such as the NIH.\u201d<br \/>\nOne winning team brings together two postdocs that work miles apart. Ang Li studies feather development in Keck School Professor of pathology Cheng-Ming Chuong\u2019s lab on the Health Sciences Campus, and Yuwei Li researches imaging techniques in Scott E. Fraser\u2019s lab on the University Park Campus.<br \/>\nTogether, they will use pioneering imaging tools to study cell behavior during feather development. Specifically, they will monitor how cells move and organize in response to bioelectric cues, or the electric currents that occur within all living organisms.<br \/>\n\u201cWhen stem cells form an organ, there are two major issues, to differentiate into the right cell types and to be organized spatially,\u201d said Chuong, principal investigator with USC Stem Cell. \u201cThe issue of organization has not been studied as extensively as differentiation. This work, when accomplished, will be a major paper.\u201d<\/p>\n<div class=\"video-embed\"><iframe loading=\"lazy\" src=\"https:\/\/www.youtube.com\/embed\/LRV4jG9sJCw\" width=\"100%\" height=\"380\" style=\"border:0;\" title=\"Doerr Stem Cell Challenge Grants: Heart regeneration and cell migration\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/div>\n<p>The other award went to a team of two postdocs in the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC \u2014 Lindsey Mork from Gage Crump\u2019s lab and Michaela Patterson from Henry Sucov\u2019s lab. Together, they will use zebrafish to investigate the role of a gene, known as Tnni3k, in heart regeneration. When activated, this gene appears to lower the number of cells called mononuclear diploid cardiomyocytes, which form new cardiac muscle following an injury such as a heart attack.<br \/>\nThe project combines the Sucov lab\u2019s expertise in heart generation with the Crump lab\u2019s knowledge of zebrafish, which have a remarkable ability to heal from severe cardiac injuries.<br \/>\n\u201cIn this project, Lindsey and Michaela directly address a fundamental question in regenerative biology: namely, the cellular basis for the profound differences in regenerative capacity between mammals and non-mammalian vertebrates such as the zebrafish,\u201d said Crump, associate professor of stem cell biology and regenerative medicine.<br \/>\nSucov \u2014 a professor of stem cell biology and regenerative medicine, cell and neurobiology, and biochemistry and molecular biology \u2014 added: \u201cI have no doubts that they will uncover important new mechanisms fundamental to heart regeneration through this project, and their success could lead to a long-standing collaboration between the two labs.\u201d<br \/>\nBy Cristy Lytal<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":168,"featured_media":341,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[637,436],"class_list":["post-339","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-release","tag-department-of-pathology","tag-usc-stem-cell"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>USC postdocs win Doerr Stem Cell Challenge 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