{"id":3462,"date":"2020-07-10T16:00:09","date_gmt":"2020-07-10T23:00:09","guid":{"rendered":"https:\/\/keck.usc.edu\/news\/the-baxter-foundation-supports-usc-research-on-epilepsy-and-lung-injury\/"},"modified":"2025-08-27T15:39:44","modified_gmt":"2025-08-27T22:39:44","slug":"the-baxter-foundation-supports-usc-research-on-epilepsy-and-lung-injury","status":"publish","type":"post","link":"https:\/\/keck.usc.edu\/news\/the-baxter-foundation-supports-usc-research-on-epilepsy-and-lung-injury\/","title":{"rendered":"The Baxter Foundation supports USC research on epilepsy and lung injury"},"content":{"rendered":"\n \n \n\n\n\n\n\n\n\n
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\n\n \n Press Release<\/span>\n\n\n\n<\/div>\n \n \n
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The Baxter Foundation supports USC research on epilepsy and lung injury<\/h1>\n\n\n<\/div>\n \n \n
\n \n July 10, 2020<\/span>\n <\/div>\n \n \n
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Ya-Wen Chen and Vishal Patel<\/figcaption>\n <\/figure>\n \n \n \n\n<\/div>\n \n\n <\/div><\/div>\n\n\n\n\n \n \n\n\n\n\n\n\n\n
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The Donald E. and Delia B. Baxter Foundation is supporting innovative biomedical research at the Keck School of Medicine of USC by granting $100,000 awards to two assistant professors:\u00a0Vishal Patel, MD, PhD, in the\u00a0USC Mark and Mary Stevens Neuroimaging and Informatics Institute<\/a>\u00a0(INI) and\u00a0Ya-Wen Chen, PhD<\/a>, in the\u00a0USC Hastings Center for Pulmonary Research<\/a>\u00a0and the\u00a0Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC<\/a>. In addition, the foundation has given $100,000 in support of the Medical Student Summer Research Fellowship program at the Keck School.<\/p>\n

Patel will use his award to study regions of abnormal brain tissue that cause seizures in epilepsy patients using\u00a0ultra-high field 7 Tesla magnetic resonance imaging (MRI)<\/a>. The INI\u2019s Siemens Magnetom Terra is the most powerful MRI scanner that is FDA-approved for clinical use, and one of only two such systems currently operating in the United States. This unique instrument will allow Patel to generate extremely high\u00a0resolution, tailored images of patients\u2019 brains to pinpoint irregularities.<\/p>\n

\u201cWe hope that this approach will allow us to identify abnormal brain tissue in more individuals compared to standard MRI,\u201d Patel said, \u201cand thus offer the\u00a0potential for a surgical cure to more of our patients who suffer from\u00a0drug-resistant epilepsy.\u201d<\/p>\n

Chen will use her $100,000 Baxter award to determine how stem cells repair lung injuries in human patients.<\/p>\n

To study this process, Chen and her team will collect adult skin or blood cells, reprogram them into induced pluripotent stem cells, and direct them to generate a specific type of lung stem cell. The scientists will then direct these lung stem cells to develop into simplified lung structures known as organoids.<\/p>\n

\u201cWe\u2019re using lung organoids to take a close look at two key molecular signals\u2014called hypoxic and Wnt\u2014that determine whether lungs repair themselves well or badly,\u201d said Chen, who is an assistant professor of medicine, and stem cell biology and regenerative medicine. \u201cThis could offer important clues about how we can avoid bad repair, such as fibrosis, in patients with serious lung injuries due to acute respiratory distress syndrome.\u201d<\/p>\n

Since 1959, the Baxter Foundation has supported USC\u2019s early-career investigators and medical students as they perform research to develop new treatments for patients. USC is one of several California educational and scientific institutions that have benefitted from the foundation\u2019s longstanding commitment to advancing research and medical innovations.<\/p>\n

\u201cWe are so pleased to be able to continue our support of USC with these new awards to Drs. Chen and Patel, and with the research fellowships for medical students,\u201d said Jane Haake Russell, president of the Baxter Foundation. \u201cBy supporting these gifted researchers at the beginning of their careers, we are able to fulfill the foundation\u2019s important mission of advancing medical research to develop new approaches for alleviating pain and prolonging human life.\u201d<\/p>\n

\u2014 By Zara Greenbaum and Cristy Lytal<\/em><\/p>\n\n\n\n<\/div>\n <\/div>\n\n\n <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":168,"featured_media":3464,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":true,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[426,78],"class_list":["post-3462","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-release","tag-hastings-center-for-pulmonary-research","tag-uncategorized"],"acf":[],"yoast_head":"\nThe Baxter Foundation supports USC research on epilepsy and lung injury<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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