{"id":419,"date":"2015-08-07T16:35:52","date_gmt":"2015-08-07T23:35:52","guid":{"rendered":"https:\/\/keck.usc.edu\/news\/usc-kidney-researcher-janos-peti-peterdi-wins-young-investigator-award\/"},"modified":"2023-11-19T12:06:28","modified_gmt":"2023-11-19T20:06:28","slug":"usc-kidney-researcher-janos-peti-peterdi-wins-young-investigator-award","status":"publish","type":"post","link":"https:\/\/keck.usc.edu\/news\/usc-kidney-researcher-janos-peti-peterdi-wins-young-investigator-award\/","title":{"rendered":"USC kidney researcher Janos Peti-Peterdi wins Young Investigator Award"},"content":{"rendered":"\n \n \n\n\n\n\n\n\n\n
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\n\n \n Press Release<\/span>\n\n\n\n<\/div>\n \n \n
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USC kidney researcher Janos Peti-Peterdi wins Young Investigator Award<\/h1>\n\n\n<\/div>\n \n \n
\n Cristy Lytal<\/span>\n \n August 07, 2015<\/span>\n <\/div>\n \n \n
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Janos Peti-Peterdi with his mother and son in 2004 (Photo by Reka Peti-Peterdi)<\/figcaption>\n <\/figure>\n \n \n \n\n<\/div>\n \n\n <\/div><\/div>\n\r\n\r\n\n\n \n \n\n\n\n\n\n\n\n
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\"Janos
Janos Peti-Peterdi with his mother and son in 2004 (Photo by Reka Peti-Peterdi)<\/figcaption><\/figure>
\nUSC kidney researcher Janos Peti-Peterdi has been selected as the 2015 recipient of the ASN-AHA Young Investigator Award. Co-sponsored by the American Society of Nephrology (ASN) and the Council on the Kidney of the American Heart Association (AHA), the annual award recognizes a kidney researcher age 45 or younger with an outstanding record of achievement and creativity.
\nPeti-Peterdi embarked early on the path to becoming a kidney researcher.
\n\u201cMy destiny was already determined before I was born,\u201d said Peti-Peterdi, professor at the Zilkha Neurogenetic Institute (ZNI) and in the Department of Physiology and Biophysics, and\u00a0principal investigator with USC Stem Cell . \u201cWhen I was born, my mother was already very ill, suffering from kidney disease. So the only way to save her was, of course, to make medicine more perfect.\u201d
\nWith this goal in mind, Peti-Peterdi earned his MD and PhD degrees at Semmelweis University and assisted in a kidney transplant clinic in Budapest, near his hometown in Hungary. In this same clinic, his mother received her own transplant nearly 20 years ago to treat her chronic kidney disease (CKD) originating from a streptococcal infection.
\nIn 1997, Peti-Peterdi moved to the United States, where he completed a postdoctoral fellowship and eventually became an assistant professor at the University of Alabama at Birmingham (UAB). At UAB, Peti-Peterdi joined an active community of nearly 40 Hungarian scholars. He played regular soccer games, and fell in love with a fellow Hungarian, Reka, who became his wife and the mother of his three children.
\nDespite this strong Hungarian presence, Alabama was challenging for him. \u201cI\u2019ll never forget the first time I went to a burger place,\u201d he said. \u201cI wanted to order a burger and French fries, and I got a cup of ice cream. So something must have been very terrible with my English. But I\u2019ve kept my Hung-lish accent.\u201d
\nAlthough he didn\u2019t pick up a Southern drawl, he did pick up research interests that persist to this day. His laboratory uses a high-resolution imaging approach, called multiphoton fluorescence microscopy, to observe how the living kidney controls blood pressure and body fluid balance under normal and disease conditions.
\nHe recently made an advance in quantitatively visualizing the function of the living kidney\u2019s filter, called the glomerulus, at the cellular and molecular level. He has now tracked individual cells of the glomerulus, shedding light on the mechanisms of both injury and regeneration.
\nWith two new grants from the National Institutes of Health (NIH), he continues to study important glomerular cell types \u2014 including podocytes, which form part of the kidney\u2019s filtration barrier, and macula densa (MD) cells, which sense and communicate subtle changes in salt concentration, fluid flow and other metabolic factors. Amgen is collaborating to target podocytes to treat kidney disease, and the AHA is funding further research into the role of MD cells in high blood pressure-related kidney injury and disease.
\n\u201cI\u2019ve always been interested in visual approaches to seeing things in the intact kidney, because it\u2019s a very complex organ,\u201d said Peti-Peterdi, who established the NIH-funded Multi-Photon Microscopy Core at USC.
\nPeti-Peterdi is also studying kidney stem cells. With a grant from the American Diabetes Association, he is investigating tissue remodeling in the diabetic kidney in hopes of finding new treatments and therapies for patients. In collaboration with the laboratory of ZNI Director Berislav Zlokovic, Peti-Peterdi is comparing the regenerative capabilities of the blood-brain barrier and the kidney\u2019s filtration barrier.
\n\u201cWe in the USC kidney research community are very fortunate to have a scientist of his caliber and collegiality,\u201d said fellow kidney researcher Andy McMahon, chair of the executive committee of USC Stem Cell.
\nIn recognition of Peti-Peterdi\u2019s growing body of research, he will accept the ASN-AHA Young Investigator Award plaque and $5,000 grant, and deliver a 35-minute address during ASN Kidney Week\u2019s plenary session on November 8 in San Diego. Recently, he was also elected to the American Society for Clinical Investigation and the European Academy of Sciences and Arts.
\n\u201cI\u2019m very optimistic about finding the ultimate cure for kidney disease, which is my lifetime goal,\u201d said Peti-Peterdi. \u201cI still, almost every day, get up and say, \u2018What can I do today to save my mother and the millions of other CKD patients from this devastating disease?\u2019 \u201d<\/p>\n\n\n\n<\/div>\n <\/div>\n\n\n <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":84,"featured_media":307,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[603,20,436,632],"class_list":["post-419","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-release","tag-department-of-physiology-and-neuroscience","tag-research","tag-usc-stem-cell","tag-usc-zilkha-neurogenetic-institute"],"acf":[],"yoast_head":"\nUSC kidney researcher Janos Peti-Peterdi wins Young Investigator Award<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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