{"id":4444,"date":"2021-11-22T08:06:05","date_gmt":"2021-11-22T16:06:05","guid":{"rendered":"https:\/\/keck.usc.edu\/news\/keck-school-researchers-hit-fda-clearance-milestone-for-ct-software\/"},"modified":"2023-11-19T12:50:04","modified_gmt":"2023-11-19T20:50:04","slug":"keck-school-researchers-hit-fda-clearance-milestone-for-ct-software","status":"publish","type":"post","link":"https:\/\/keck.usc.edu\/news\/keck-school-researchers-hit-fda-clearance-milestone-for-ct-software\/","title":{"rendered":"Keck School researchers hit FDA clearance milestone for CT software"},"content":{"rendered":"\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--article-hero \"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--article-hero\"\n    \n      >\n\n    \n  <div class=\"text-container\">\n              \n<div class=\"f--field f--eyebrow\">\n\n    \n  <span>Press Release<\/span>\n\n\n\n<\/div>\n    \n              \n<div class=\"f--field f--page-title\">\n\n    \n  <h1>Keck School researchers hit FDA clearance milestone for CT software<\/h1>\n\n\n<\/div>\n    \n    \n          <div class=\"meta\">\n                  <span class=\"author\">Sidney Taiko Sheehan<\/span>\n        \n                  <span class=\"date\">November 22, 2021<\/span>\n              <\/div>\n    \n              \n<div class=\"f--field f--embed\">\n\n    \n  <div class=\"heateor_sss_sharing_container heateor_sss_horizontal_sharing\" data-heateor-ss-offset=\"0\" data-heateor-sss-href='https:\/\/keck.usc.edu\/news\/keck-school-researchers-hit-fda-clearance-milestone-for-ct-software\/'><div class=\"heateor_sss_sharing_ul\"><a aria-label=\"Facebook\" class=\"heateor_sss_facebook\" href=\"https:\/\/www.facebook.com\/sharer\/sharer.php?u=https%3A%2F%2Fkeck.usc.edu%2Fnews%2Fkeck-school-researchers-hit-fda-clearance-milestone-for-ct-software%2F\" title=\"Facebook\" rel=\"nofollow noopener\" target=\"_blank\" 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11.903 5 10.826c0-1.08.382-1.993 1.146-2.738L8.128 6.12C8.873 5.372 9.785 5 10.864 5c1.087 0 2.004.382 2.75 1.146l2.777 2.79c.75.747 1.12 1.66 1.12 2.737 0 1.105-.392 2.045-1.183 2.817l1.186 1.186c.774-.79 1.708-1.186 2.805-1.186 1.078 0 1.995.377 2.75 1.132l2.804 2.804c.754.755 1.13 1.672 1.13 2.75z\"\/><\/svg><\/span><\/a><\/div><div class=\"heateorSssClear\"><\/div><\/div>\n\n\n<\/div>\n        \n  <\/div>\n\n          \n<div class=\"f--field f--image\">\n\n    \n    \n    \n        <figure>\n    \n    \n    \n              \n      <img\n                            data-src=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/iStock-CT-scan-724x432.jpg\"\n                    data-sizes=\"(min-width:1200px) 75vw, (min-width:768px) 83vw, 100vw\"          class=\"lazyload\"\n        \n        \n        \n                                      \/>\n\n    \n          <figcaption>Compared to existing low-dose CT technologies, the research team\u2019s KWIA technique has the advantages of fast computation speed and excellent retention of the texture and resolution of CT images. (Photo\/Courtesy of Danny JJ Wang)<\/figcaption>\n    <\/figure>\n    \n  \n  \n\n<\/div>\n  \n\n  <\/div><\/div>\n\r\n\r\n\n\n  \n    \n\n\n\n\n\n\n<div\n  class=\"cc--component-container cc--rich-text white\"\n\n  \n  \n  \n  \n  \n  \n  >\n  <div class=\"c--component c--rich-text\"\n    \n      >\n\n    \n  <div class=\"inner-wrapper\">\n        \n<div class=\"f--field f--wysiwyg\">\n\n    \n  <p>Just last year, <a href=\"https:\/\/profiles.sc-ctsi.org\/danny.wang\">Danny JJ Wang, PhD<\/a>, director of imaging technology innovation at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (<a href=\"https:\/\/ini.usc.edu\/\">USC INI<\/a>) and his team at the start-up company <a href=\"http:\/\/www.huraimaging.com\/\">Hura Imaging, Inc.<\/a>, received a two-year, $1.6 million grant from the National Institutes of Health\u2019s <a href=\"https:\/\/www.sbir.gov\/\">Small Business Innovation Research<\/a> (SBIR). The SBIR program supports the translation of technologies from the lab to commercial use through small business innovation and commercialization.<\/p>\n<p>Wang and his team are addressing the growing concern that radiation involved in computed tomography (CT) scans can be unnecessarily harmful to patients. CT scans can certainly save lives by catching abnormalities, but there is a strong desire for methods that can lower the risk of cancer with reduced use of radiation. However, low dose CT scans result in low contrast or noisy images.<\/p>\n<p>\u201cOur technology reduces the image noise of CT perfusion and improves image contrast by about 50-75% without compromising imaging speed,\u201d says Wang. \u201cCompared to existing low-dose CT technologies, our technique has the advantages of fast computation speed and excellent retention of the texture and resolution of CT images. We are delighted to report that we have now received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for our CT perfusion software (Hura CTP<sup>TM<\/sup>).\u201d<\/p>\n<figure id=\"attachment_124739\" aria-describedby=\"caption-attachment-124739\" style=\"width: 187px\" class=\"wp-caption alignright\"><a href=\"https:\/\/keck.usc.edu\/wp-content\/uploads\/2021\/11\/Danny-Wang.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-124739 \" src=\"https:\/\/keck.usc.edu\/news\/wp-content\/uploads\/sites\/68\/2023\/11\/Danny-Wang-210x300.png\" alt=\"\" width=\"187\" height=\"267\" \/><\/a><figcaption id=\"caption-attachment-124739\" class=\"wp-caption-text\"><em>Danny JJ Wang<\/em><\/figcaption><\/figure>\n<p>\u201cDr. Wang\u2019s technique dramatically improves the quality and signal-to-noise ratio of CT perfusion images, with minimal additional computation time,\u201d says\u00a0<a href=\"https:\/\/keck.usc.edu\/faculty-search\/vinay-anant-duddalwar\/\">Vinay Duddalwar, MD<\/a>, professor of clinical radiology at the Keck School of Medicine of USC. \u201cThe technology may impact the safety and clinical practice of CT perfusion.\u201d Dr. Duddalwar is the lead investigator of the SBIR study at the Keck School.<\/p>\n<p>FDA <a href=\"https:\/\/www.fda.gov\/medical-devices\/premarket-submissions\/premarket-notification-510k\">510(k) clearance<\/a> is a critical and necessary step when preparing a \u201cdevice\u201d for market in the U.S. \u201cDr. Wang set out with the goal of leading the INI\u2019s efforts to use our computational resources and expertise in clinical imaging to make CT scans safer while improving image quality,\u201d says\u00a0<a href=\"https:\/\/keck.usc.edu\/faculty-search\/arthur-w-toga\/\">Arthur W. Toga, PhD<\/a>, provost professor of ophthalmology, neurology, psychiatry and the behavioral sciences, radiology and engineering, the Ghada Irani chair in neuroscience at the Keck School, and director of the INI. \u201cDr. Wang is now one step closer to commercializing this work so that it can be widely used in clinical practice to help keep patients safe while improving the quality of clinical care.\u201d<\/p>\n<p>The INI is collaborating with USC\u2019s radiology department and Hura Imaging. The INI provides the facilities and computational resources through its Laboratory of Neuro Imaging (<a href=\"https:\/\/loni.usc.edu\/\">LONI<\/a>) and Hura Imaging is handling commercialization of the technology. \u201cI\u2019m grateful for the opportunity to impact translational research and to celebrate this milestone with my colleagues,\u201d says Wang.<\/p>\n\n\n\n<\/div>\n  <\/div>\n\n\n  <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Wang and his team are addressing the growing concern that radiation involved in computed tomography (CT) scans can be unnecessarily harmful to patients.<\/p>\n","protected":false},"author":156,"featured_media":4447,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[20],"class_list":["post-4444","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-release","tag-research"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Keck School researchers hit FDA clearance milestone for CT software<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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