{"id":451,"date":"2015-09-15T16:41:58","date_gmt":"2015-09-15T23:41:58","guid":{"rendered":"https:\/\/keck.usc.edu\/news\/kast-lab-wins-top-prize-in-rare-disease-science-challenge\/"},"modified":"2023-11-26T08:16:41","modified_gmt":"2023-11-26T16:16:41","slug":"kast-lab-wins-top-prize-in-rare-disease-science-challenge","status":"publish","type":"post","link":"https:\/\/keck.usc.edu\/news\/kast-lab-wins-top-prize-in-rare-disease-science-challenge\/","title":{"rendered":"Kast Lab wins top prize in rare disease science challenge"},"content":{"rendered":"\n \n \n\n\n\n\n\n\n\n
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\n\n \n Press Release<\/span>\n\n\n\n<\/div>\n \n \n
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Kast Lab wins top prize in rare disease science challenge<\/h1>\n\n\n<\/div>\n \n \n
\n \n September 15, 2015<\/span>\n <\/div>\n \n \n
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Martin Kast, PhD, of the USC Norris Comprehensive Cancer Center meets with one of the Indonesian "Treemen," who suffer from an uncontrolled infection and proliferation of warts caused by the human papillomavirus.<\/figcaption>\n <\/figure>\n \n \n \n\n<\/div>\n \n\n <\/div><\/div>\n\r\n\r\n\n\n \n \n\n\n\n\n\n\n\n
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\nMartin Kast<\/a>, PhD, of the USC Norris Comprehensive Cancer Center and his students Joseph Skeate and Andrew Woodham, PhD, earned top prize in the 2015\u00a0BeHEARD Rare Disease Science Challenge<\/a>\u00a0from the Rare Genomics Institute.
\nThe prize, provided by Cypher Genomics and valued at $100,000, will allow the\u00a0Kast Lab<\/a>\u00a0to push forward in its research into genetic variations that result in uncontrolled infection and proliferation of warts caused by the human papillomavirus within Indonesian \u201cTreemen.\u201d
\nIn 2009, Kast first met individuals with the illness, which handicaps them with massive tree bark-like outgrowths. Kast believes that the Treemen have a genetic variation that prevents their immune systems from mounting a proper attack against HPV infections.
\nWith only a few reported cases worldwide, funding for study has been scarce. The prize will allow the Kast Lab to sequence the genomes of the three Treemen and compare them to other healthy Indonesians from the region, potentially solving the mystery of why their immune systems cannot eliminate the virus.\n<\/div>\n
<\/div>\n\n\n\n<\/div>\n <\/div>\n\n\n <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":168,"featured_media":452,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[10,596,20],"class_list":["post-451","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-release","tag-cancer","tag-department-of-immunology-and-immune-therapeutics","tag-research"],"acf":[],"yoast_head":"\nKast Lab wins top prize in rare disease science challenge<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/keck.usc.edu\/news\/kast-lab-wins-top-prize-in-rare-disease-science-challenge\/\" \/>\n<meta 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